Anthocyanin fraction from potato extracts is cytotoxic to prostate cancer cells through activation of caspase-dependent and caspase-independent pathways

Carcinogenesis

Volumn 28, Issue 10, 2007, Pages 2227-2235

  Reddivari, Lavanya ^a   Vanamala, Jairam ^a   Chintharlapalli, Sudhakar ^c   Safe, Stephen H ^b,c   Miller Jr , J Creighton ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANTHOCYANIN; ANTINEOPLASTIC AGENT; ANTIOXIDANT; APOPTOSIS INDUCING FACTOR; CARBOXYLIC ACID; CYCLIN DEPENDENT KINASE INHIBITOR 1B; ENDONUCLEASE G; MITOGEN ACTIVATED PROTEIN KINASE; PHENOL DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CULTIVAR; CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; MITOSIS INHIBITION; POTATO; PRIORITY JOURNAL; PROSTATE CANCER;

ANTHOCYANINS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CASPASES; CELL DIVISION; CELL LINE, TUMOR; FRUIT; HUMANS; MALE; PHENOL; PLANT EXTRACTS; PROSTATIC NEOPLASMS; SOLANUM TUBEROSUM; VEGETABLES;

EID: 35148834671     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm117     Document Type: Article

References (49)

1. American Cancer Society (2006) Overview: Prostate cancer.
2. Veluri,R. et al. (2006) Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells. Carcinogenesis, 27, 1445-1453.
3. Yi,W. et al. (2005) Phenolic compounds from blueberries can inhibit colon cancer cell proliferation and induce apoptosis. J. Agric. Food Chem., 53, 7320-7329.
4. Matito,C. et al. (2003) Antiproliferative effect of antioxidant polyphenols from grape in murine Hepa-1c1c7. Eur. J. Nutr., 42 43-49.
5. Davis-Searles,P.R. et al. (2005) Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells. Cancer Res., 65, 4448-4457.
6. Singh,R.P. et al. (2002) Flavonoid antioxidant silymarin and skin cancer. Antioxid. Redox Signal., 4, 655-663.
7. Ho,E. et al. (2004) Dietary influences on endocrine-inflammatory interactions in prostate cancer development. Arch. Biochem. Biophys. 428, 109-117.
8. Saddler,S.S. (2003) Potential mechanism of phytochemical induced apoptosis in human prostate cancer cells: Genistein and β-lapachone. Florida Atlantic University, MS Thesis Boca Raton, Florida.
9. Yang,C.S. et al. (2001) Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu. Rev. Nutr., 21, 381-406.
10. Nijveldt,R.J. et al. (2001) Flavonoids: A review of probable mechanisms of action and potential applications. Am. J. Clin. Nutr. 74, 418-425.
11. Guarini,L. et al. (1992) Growth inhibition and modulation of antigenic phenotype in human melanoma and glioblastoma multiforme cells by caffeic acid phenethyl ester (CAPE). Cell. Mol. Biol., 38 513-527.
12. Nichenametla,S.N. et al. (2006) A review of the effects and mechanisms of polyphenolics in cancer. Crit. Rev. Food Sci. Nutr., 46, 161-183.
13. Martin,S. et al. (2003) Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2. Biochem. Pharmacol., 65, 669-675.
14. Shih,P.H. et al. (2005) Effects of anthocyanidin on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells. Food Chem. Toxicol., 43, 1557-1566.
15. Yi,W. et al. (2005) Study of anticancer activities of muscadine grape phenolics in vitro. J. Agric. Food Chem., 53, 8804-8812.
16. Stoner,G.D. et al. (2006) Protection against esophageal cancer in rodents with lyophilized berries: Potential mechanisms. Nutr. Cancer 54, 33-46.
17. Al-Saikhan,M.S. et al. (1995) Antioxidant activity and total phenolics in different genotypes of potato (Solanum tuberosum, L). J. Food Sci., 60, 341-343.
18. Brown,C.R. (2005) Antioxidants in potato. Am. J. Potato Res., 82, 163-172.
19. Shakya,R. et al. (2006) Rapid screening of ascorbic acid, glycoalkaloids, and phenolics in potato using high-performance liquid chromatography. J. Agric. Food Chem., 54, 5253-5260.
20. Nara,K. et al. (2006) Antioxidative activity of bound-form phenolics in potato peel. Biosci. Biotechnol. Biochem., 70, 1489-1491.
21. Al-Saikhan,M.S. (2000) Antioxidants, proteins, and carotenoids in potato. (Solanum tuberosum, L). Ph.D. Department of Horticutural Sciences. Texas A&M University, College Station.
22. Kanatt,S.R. et al. (2005) Potato peel extract-a natural antioxidant for retarding lipid peroxidation in radiation processed lamb meat. J. Agric. Food Chem., 53, 1499-1504.
23. Giusti,M.M. et al. (1999) Electrospray and tandem mass spectroscopy as tools for anthocyanin characterization. J. Agric. Food Chem., 47, 4657-4664.
24. Giusti,M.M. et al. (1999) Molar absorptivity and color characteristics of acylated and non-acylated pelargonidin-based anthocyanins. J. Agric. Food Chem., 47, 4631-4637.
25. Brand-Williams,W. et al. (1995) Use of free radical method to evaluate antióxidant activity. Lebensm. Wiss. Technol., 28 25-30.
26. Singleton,V.L. et al. (1999) Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Meth. Enzymol., 299, 152-178.
27. Ory,B. et al. (2007) Zoledronic acid activates the DNA S phase checkpoint and induces osteosarcoma cell death characterized by AIF and EndoG translocation independently of p53 and Rb status. Mol. Pharmacol., 71, 333-343.
28. Hou,D.X et al. (2003) Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: Structure-activity relationship and mechanisms involved. Int. J. Oncol., 23, 705-712.
29. Hou,D.X. et al. (2005) Delphinidin 3-sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species-mediated mitochondrial pathway. Arch. Biochem. Biophys., 440, 101-109.
30. Lei,P. et al. (2006) 1,1-Bis(3′-indolyi)-1-(p-substituted phenyl)methanes inhibit ovarian cancer cell growth through peroxisome proliferator-activated receptor-dependent and independent pathways. Mol. Cancer Ther., 5, 2324-2336.
31. Nakano,T. et al. (2006) Endoplasmic reticulum Ca2+ depletion induces endothelial cell apoptosis independently of caspase-12. Cardiovasc. Res., 69, 908-915.
32. Sato,M. et al. (2001) Grape seed proanthocyanidin reduces cardiomyocyte apoptosis by inhibiting ischemia/reperfusion-induced activation of JNK-1 and C-JUN. Free Radic. Biol. Med., 31, 729-737.
33. Chae,H.J. et al. (2004) Ge-Jee-Bok-Ryung-Hwan induces apoptosis in human cervical carcinoma HeLa cells - an endoplasmic reticulum stress pathway. Life Sci., 75, 2997-3016.
34. Uramoto,H. et al. (2005) Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance. Lung Cancer, 41, 55-62.
35. Hung,H.C. et al. (2004) Fruit and vegetable intake and risk of major chronic disease, J. Natl Cancer Inst., 96, 1577-1584.
36. Cohen,J.H. et al. (2000) Fruit and vegetable intakes and prostate cancer risk. J. Natl Cancer Inst., 92, 61-68.
37. Kolonel,L.N. et al. (2000) Vegetables, fruits, legumes and prostate cancer: A multiethnic case-control study. Cancer Epidemiol. Biomarkers Prev., 9, 795-804.
38. Rashidkhani,B. et al. (2005) Fruits, vigetables and risk of renal cell carcinoma: A prospective study of Swedish women. Int. J. Cancer 113, 451-455.
39. Koehn,F.E. et al. (2005) The evolving role of natural products in drug discovery. Nat. Rev. Drug Discov., 4, 206-220.
40. Chang,Y.C. et al. (2005) Hibiscus anthocyanins rich extract-induced aptotic cell death in human promyelocytic leukemia cells. Toxicol. Appl. Pharmacol. 205, 201-212.
41. Chen,P.N. et al. (2005) Cyanidin 3-glucoside and peonidin 3-glucoside inhibit tumor cell growth and induce apoptosis in vitro and suppress tumor growth in vivo. Nutr. Cancer, 53, 232-243.
42. Fimognari,C. et al. (2005) In vitro antitumor activity of cyanidin-3-O-beta-glucopyranoside. Chemotherapy, 51, 332-335.
43. Guerra,M.C.,et al. (2005) Cyanidin-3-O-beta-glucopyraposide, a natural free-radical scavenger against aflatoxin B1-and ochratoxin A-induced cell damage in a human hepatoma cell line (Hep G2) and a human colonic adehocarcinoma cell line (CaCo-2). Br. J. Nutr., 94, 211-220.
44. Lazze,M.C. et al. (2004) Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines. Carcinoginesis, 25, 1427-1433.
45. Yeh,C.T. et al. (2005) Induction of apoptosis by the anthocyanidins through regulation of Bcl-2 gene and activation of c-Jun N-terminal kinase cascade in hepatoma cells. J. Agric. Food Chem., 53, 1740-1749.
46. Arnoult,D. et al. (2003) Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization. EMBO J., 22,4385-4399.
47. Cande,C. et al. (2002) Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death? J. Cell Sci. 115, 4727-4734.
48. Cande,C. et al. (2002) Apoptosis-inducing factor (AIF): A novel caspase-independent death effector released from mitochondria. Biochimie, 84, 215-222.
49. Kang,Y.H. et al. (2004) Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: Reactive oxygen species-mediates poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria. Cancer Res., 64, 8960-8967.