The transmembrane segment S6 determines cation versus anion selectivity of TRPM2 and TRPM8

Journal of Biological Chemistry

Volumn 282, Issue 38, 2007, Pages 27598-27609

  Kühn, Frank J P ^a   Knop, Gabriel ^a,b   Lückhoff, Andreas ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF OLDENBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; DEPOLARIZATION; NEGATIVE IONS;

CATION CHANNELS; CHIMERA; HOMOLOGY; TRANSMEMBRANE SEGMENTS;

GENETIC ENGINEERING;

ANION CHANNEL; ANION TRANSPORT PROTEIN; CALCIUM; CATION CHANNEL; GLUTAMIC ACID; LYSINE; MEMBRANE PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL M;

ANIMAL CELL; ANION TRANSPORT; ARTICLE; CELL CULTURE; CHIMERA; CONTROLLED STUDY; ELECTROPHYSIOLOGY; GENETIC TRANSFECTION; ION PERMEABILITY; MOLECULAR CLONING; NONHUMAN; PH; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ADENOSINE DIPHOSPHATE RIBOSE; AMINO ACID SEQUENCE; ANIMALS; ANIONS; CATIONS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MEGLUMINE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; TRPM CATION CHANNELS;

EID: 34948865896     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702247200     Document Type: Article

References (46)

1. Long, S. B., Campbell, E. B., and McKinnon, R. (2005) Science 309, 903-908
2. Lu, Z., Klem, A. M., and Ramu, Y. (2005) J. Gen. Physiol. 120, 663-676
3. Peier, A. M., Moqrich, A., Hergarden, A. C., Reeve, A. J., Andersson, D. A., Story, G. M., Earley, T. J., Dragoni, I., McIntyre, P., Bevan, S., and Patapoutian, A. (2002) Cell 108, 705-715
4. Perraud, A. L., Fleig, A., Dunn, C. A., Bagley, L. A., Launay, P., Schmitz, C., Stokes, A. J., Zhu, Q., Bessman, M. J., Penner, R., Kinet, J. P., and Scharenberg, A. M. (2001) Nature 411, 595-599
5. Wehage, E., Eisfeld, J., Heiner, I., Jüngling, E., Zitt, C., and Lückhoff, A. (2002) J. Biol. Chem. 277, 23150-23156
6. Hara, Y., Wakamori, M., Ishii, M., Maeno, E., Nishida, M., Yoshida, T., Yamada, H., Shimizu, S., Mori, E., Kudoh, J., Shimizu, N., Kurose, H., Okada, Y., Imoto, K., and Mori, Y. (2002) Mol. Cell 9, 163-173
7. Zhang, W., Chu, X., Tong, Q., Cheung, J. Y., Conrad, K., Masker, K., and Miller, B. A. (2003) J. Biol. Chem. 278, 16222-16229
8. Zhang, W., Hirschler-Laszkiewicz, I., Tong, Q., Contrad, K., Sun, S. C., Penn, L., Barber, D. L., Stahl, R., Carey, D. J., Cheung, J. Y., and Miller, B. A. (2006) Am. J. Physiol. 290, C1146-C1159
9. Kraft, R., Grimm, C., Grosse, K., Hoffmann, A., Sauerbruch, S., Kettenmann, H., Schultz, G., and Harteneck, C. (2004) Am. J. Physiol. 286, 129-137
10. Fonfria, E., Marshall, I. C., Benham, C. D., Boyfield, I., Brown, J. D., Hill, K., Hughes, J. P., Skaper, S. D., and McNulty, S. (2004) Br. J. Pharmacol. 143, 186-192
11. Fonfria, E., Marshall, I. C., Boyfield, I., Skaper, S. D., Hughes, J. P., Owen, D. E., Zhang, W., Miller, B. A., Benham, C. D., and McNulty, S. (2005) J. Neurochem. 95, 715-723
12. Perraud, A. L., Takanishi, C. L., Shen, B., Kang, S., Smith, M. K., Schmitz, C., Knowles, H. M., Ferraris, D., Li, W., Zhang, J., Stoddard, B. L., and Scharenberg, A. M. (2005) J. Biol. Chem. 280, 6138-6148
13. Kaneko, S., Kawakami, S., Hara, Y., Wakamori, M., Itoh, E., Minami, T., Takada, Y., Kume, T., Katsuk, H., Mori, Y., and Akaike, A. (2006) J. Pharmacol. Sci. 101, 66-76
14. Grubisha, O., Rafty, A. L., Takanishi, C. L., Xu, X., Tong, L., Perraud, A. L., Scharenberg, A. M., and Denu, J. M. (2006) J. Biol. Chem. 281, 14057-14065
15. Reid, G., Babes, A., and Pluteanu, F. (2002) J. Physiol. 542, 595-614
16. McKemy, D. D., Neuhausser, W. M., and Julius, D. (2002) Nature 416, 52-58
17. Tsavaler, L., Shapero, M. H., Morkowski, S., and Laus, R. (2001) Cancer Res. 61, 3760-3769
18. Brauchi, S., Orio, P., and Latorre, R. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 15494-15499
19. Voets, T., Droogmans, G., Wissenbach, U., Janssens, A., Flockerzi, V., and Nilius, B. (2004) Nature 430, 748-754
20. Voets, T., Owsianik, G., Jannssens, A., Talavera, K., and Nilius, B. (2007) Nat. Chem. Biol. 3, 174-182
21. Rohacs, T., Lopes, C. M. B., Michailidis, I., and Logothetis, D. E. (2005) Nat. Neurosci. 8, 626-634
22. Vanden Abeele, F., Zholos, A., Bidaux, G., Shuba, Y., Thebault, S., Beck, B., Flourakis, M., Panchin, Y., Skryma, R., and Prevarskaya, N. (2006) J. Biol. Chem. 281, 40174-40182
23. Kühn, F. J. P., and Lückhoff, A. (2004) J. Biol. Chem. 279, 46431-46437
24. Garcia-Martinez, C., Morenilla-Palao, C., Planells-Cases, R., Merino, J. M., and Ferrer-Montiel, A. (2000) J. Biol. Chem. 275, 32552-32558
25. Nilius, B., Vennekens, R., Prenen, J., Hoenderop, J. G. J., Droogmans, G., and Bindels, R. J. M. (2001) J. Biol. Chem. 276, 1020-1025
26. Nilius, B., Prenen, J., Janssens, A., Owsianik, G., Wang, C., Zhu, M. X., and Voets, T. (2005) J. Biol. Chem. 280, 22899-22906
27. Nilius, B., Mahieu, F., Prenen, J., Janssens, A., Owsianik, G., Vennekens, R., and Voets, T. (2006) EMBO J. 25, 467-478
28. Voets, T., Prenen, J., Vriens, J., Watanabe, H., Janssens, A., Wissenbach, U., Bodding, M., Droogmans, G., and Nilius, B. (2002) J. Biol. Chem. 277, 33704-33710
29. Sano, Y., Inamura, K., Miyake, A., Mochizuki, S., Yokoi, H., Matsushime, H., and Furuichi, K. (2001) Science 293, 1327-1330
30. McHugh, D., Flemming, R., Xu, S. Z., Perraud, A. L., and Beech, D. J. (2003) J. Biol. Chem. 278, 11002-11006
31. Heiner, I., Eisfeld, J., Warnstedt, M., Radukina, N., Jüngling, E., and Lückhoff, A. (2006) Biochem. J. 371, 1045-1053
32. Kraft, R., Grimm, C., Frenzel, H., and Harteneck, C. (2006) Br. J. Pharmacol. 148, 264-273
33. Estacion, M., Sinkins, W. G., Jones, S. W., Applegate, M. A., and Schilling, W. P. (2006) J. Physiol. 15, 359-377
34. Owsianik, G., Talavera, K., Voets, T., and Nilius, B. (2006) Annu. Rev. Physiol. 68, 685-717
35. Sancho, J., Serrano, L., Fersht, A. R. (1992) Biochemistry 31, 2253-2258
36. Keramidas, A., Moorhouse, A. J., Schofield, P. R., and Barry, P. H. (2004) Prog. Biophys. Mol. Biol. 86, 161-204
37. Barry, P. H., and Lynch, J. W. (2005) Nanobioscience 4, 70-80
38. Gunthorpe, M. J., and Lummis, C. R. (2001) J. Biol. Chem. 276, 10977-10983
39. Keramidas, A., Moorhouse, A. J., Pierce, K. D., Schofield, P. R., and Barry, P. H. (2002) J. Gen. Physiol. 119, 393-410
40. MacKinnon, R. (1995) Neuron 14, 889-892
41. Qu, W., Moorhouse, A. J., Chandra, M., Pierce, K. D., Lewis, T. M., and Barry, P. H. (2006) J. Gen. Physiol. 127, 375-389
42. Zitt, C., Obukhov, A. G., Strübing, C., Zobel, A., Kalkbrenner, F., Lückhoff, A., and Schultz, G. (1997) J. Cell Biol. 138, 1333-1341
43. Flockerzi, V. (2006) in Transient Receptor Potential (TRP) Channels (Flockerzi, V., and Nilius, B., eds), pp. 1-49, Springer-Verlag, Heidelberg, Germany
44. Mei, Z. Z., Mao, H. J., and Jiang, L. H. (2006) Am. J. Physiol. 291, 1022-1028
45. Hille, B. (1992) Ion Channels of Excitable Membranes, 2nd Ed., pp. 337-361 Sinauer Associates, Sunderland, MA
46. Brauchi, S., Orta, G., Mascayano, C., Salazar, M., Raddatz, N., Urbina, H., Rosenmann, E., Gonzales-Nilo, F., and Latorre, R. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 10246-10251