MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits interleukin-1-induced matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation

Cellular Signalling

Volumn 19, Issue 12, 2007, Pages 2549-2557

  Ahmad, Rasheed ^a   Sylvester, Judith ^a   Zafarullah, Muhammad ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Cartilage; Gene regulation; Interleukin 1; IRAK1; Matrix metalloproteinase 13; MyD88; Rheumatoid arthritis; RNA interference; Signal transduction; TRAF6; Transcription factors

Indexed keywords

ADAPTOR PROTEIN; COLLAGENASE 3; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CELLS, CULTURED; CHONDROCYTES; DIMERIZATION; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 13; MITOGEN-ACTIVATED PROTEIN KINASES; MYELOID DIFFERENTIATION FACTOR 88; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDES; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-JUN; RNA INTERFERENCE; RNA, SMALL INTERFERING; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

EID: 34948850322     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2007.08.013     Document Type: Article

References (49)

1. Dayer J.M., and Bresnihan B. Arthritis Rheum. 46 (2002) 574
2. Tetlow L.C., Adlam D.J., and Woolley D.E. Arthritis Rheum. 44 (2001) 585
3. Gruber J., Vincent T.L., Hermansson M., Bolton M., Wait R., and Saklatvala J. Arthritis Rheum. 50 (2004) 2539
4. Martel-Pelletier J., McCollum R., DiBattista J., Faure M.P., Chin J.A., Fournier S., Sarfati M., and Pelletier J.P. Arthritis Rheum. 35 (1992) 530
5. Goldring M.B., Birkhead J.R., Suen L.F., Yamin R., Mizuno S., Glowacki J., Arbiser J.L., and Apperley J.F. J. Clin. Invest. 94 (1994) 2307
6. Liacini A., Sylvester J., Li W.Q., and Zafarullah M. Matrix Biol. 21 (2002) 251
7. Temple M.M., Xue Y., Chen M.Q., and Sah R.L. Arthritis Rheum. 54 (2006) 3267
8. Joosten L.A., Helsen M.M., Saxne T., van De Loo F.A., Heinegard D., and van Den Berg W.B. J. Immunol. 163 (1999) 5049
9. Evans C.H., Gouze J.N., Gouze E., Robbins P.D., and Ghivizzani S.C. Gene Ther. 11 (2004) 379
10. Neidhart M., Gay R.E., and Gay S. Arthritis Rheum. 43 (2000) 1719
11. Abramson S.B., and Amin A. Rheumatology (Oxford) 41 (2002) 972
12. Kobayashi M., Squires G.R., Mousa A., Tanzer M., Zukor D.J., Antoniou J., Feige U., and Poole A.R. Arthritis Rheum. 52 (2005) 128
13. Bau B., Gebhard P.M., Haag J., Knorr T., Bartnik E., and Aigner T. Arthritis Rheum. 46 (2002) 2648
14. Mitchell P.G., Magna H.A., Reeves L.M., Lopresti-Morrow L.L., Yocum S.A., Rosner P.J., Geoghegan K.F., and Hambor J.E. J. Clin. Invest. 97 (1996) 761
15. Fosang A.J., Last K., Knauper V., Murphy G., and Neame P.J. FEBS Lett. 380 (1996) 17
16. Heathfield T.F., Onnerfjord P., Dahlberg L., and Heinegard D. J. Biol. Chem. 279 (2004) 6286
17. Monfort J., Tardif G., Reboul P., Mineau F., Roughley P., Pelletier J.P., and Martel-Pelletier J. Arthritis Res. Ther. 8 (2006) R26
18. Yasuda T., Tchetina E., Ohsawa K., Roughley P.J., Wu W., Mousa A., Ionescu M., Pidoux I., and Poole A.R. Matrix Biol. 25 (2006) 419
19. Fichter M., Korner U., Schomburg J., Jennings L., Cole A.A., and Mollenhauer J. J. Orthop. Res. 24 (2006) 63
20. Wernicke D., Seyfert C., Gromnica-Ihle E., and Stiehl P. Autoimmunity 39 (2006) 307
21. Ma G.F., Ali A., Verzijl N., Hanemaaijer R., TeKoppele J., Konttinen Y.T., and Salo J. Arthritis Rheum. 54 (2006) 2928
22. Joronen K., Ala-aho R., Majuri M.L., Alenius H., Kahari V.M., and Vuorio E. Ann. Rheum. Dis. 63 (2004) 656
23. Neuhold L.A., Killar L., Zhao W., Sung M.L., Warner L., Kulik J., Turner J., Wu W., Billinghurst C., Meijers T., Poole A.R., Babij P., and DeGennaro L.J. J. Clin. Invest. 107 (2001) 35
24. Geng Y., Valbracht J., and Lotz M. J. Clin. Invest. 98 (1996) 2425
25. Firestein G.S., and Manning A.M. Arthritis Rheum. 42 (1999) 609
26. O'Neill L.A., and Greene C. J. Leukoc. Biol. 63 (1998) 650
27. Loiarro M., Sette C., Gallo G., Ciacci A., Fanto N., Mastroianni D., Carminati P., and Ruggiero V. J. Biol. Chem. 280 (2005) 15809
28. Shlopov B.V., Lie W.R., Mainardi C.L., Cole A.A., Chubinskaya S., and Hasty K.A. Arthritis Rheum. 40 (1997) 2065
29. Liacini A., Sylvester J., Li W.Q., Huang W., Dehnade F., Ahmad M., and Zafarullah M. Exp. Cell Res. 288 (2003) 208
30. Pendas A.M., Balbin M., Llano E., Jimenez M.G., and Lopez-Otin C. Genomics 40 (1997) 222
31. Mengshol J.A., Vincenti M.P., and Brinckerhoff C.E. Nucleic Acids Res. 29 (2001) 4361
32. Han Z., Boyle D.L., Chang L., Bennett B., Karin M., Yang L., Manning A.M., and Firestein G.S. J. Clin. Invest. 108 (2001) 73
33. Migita K., Miyashita T., Maeda Y., Aoyagi T., Kawabe Y., Nakamura M., Yatsuhashi H., Ishibashi H., and Eguchi K. Immunol. Lett. 98 (2005) 194
34. Joosten L.A., Koenders M.I., Smeets R.L., Heuvelmans-Jacobs M., Helsen M.M., Takeda K., Akira S., Lubberts E., van De Loo F.A., and van Den Berg W.B. J. Immunol. 171 (2003) 6145
35. Choe J.Y., Crain B., Wu S.R., and Corr M. J. Exp. Med. 197 (2003) 537
36. Kyo F., Futani H., Matsui K., Terada M., Adachi K., Nagata K., Sano H., Tateishi H., Tsutsui H., and Nakanishi K. Arthritis Rheum. 52 (2005) 2530
37. Chen C.J., Shi Y., Hearn A., Fitzgerald K., Golenbock D., Reed G., Akira S., and Rock K.L. J. Clin. Invest. 116 (2006) 2262
38. Liu-Bryan R., Scott P., Sydlaske A., Rose D.M., and Terkeltaub R. Arthritis Rheum. 52 (2005) 2936
39. Kanakaraj P., Schafer P.H., Cavender D.E., Wu Y., Ngo K., Grealish P.F., Wadsworth S.A., Peterson P.A., Siekierka J.J., Harris C.A., and Fung-Leung W.P. J. Exp. Med. 187 (1998) 2073
40. MacGillivray M.K., Cruz T.F., and McCulloch C.A. J. Biol. Chem. 275 (2000) 23509
41. Li X., Commane M., Jiang Z., and Stark G.R. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 4461
42. Suzuki N., Suzuki S., Duncan G.S., Millar D.G., Wada T., Mirtsos C., Takada H., Wakeham A., Itie A., Li S., Penninger J.M., Wesche H., Ohashi P.S., Mak T.W., and Yeh W.C. Nature 416 (2002) 750
43. Kawai T., and Akira S. Arthritis Res. Ther. 7 (2005) 12
44. Ospelt C., Kyburz D., Pierer M., Seibl R., Kurowska M., Distler O., Neidhart M., Muller-Ladner U., Pap T., Gay R.E., and Gay S. Ann. Rheum. Dis. 63 Suppl 2 (2004) ii90
45. Su S.L., Tsai C.D., Lee C.H., Salter D.M., and Lee H.S. Osteoarthr. Cartil. 13 (2005) 879
46. Kim H.A., Cho M.L., Choi H.Y., Yoon C.S., Jhun J.Y., Oh H.J., and Kim H.Y. Arthritis Rheum. 54 (2006) 2152
47. Seibl R., Birchler T., Loeliger S., Hossle J.P., Gay R.E., Saurenmann T., Michel B.A., Seger R.A., Gay S., and Lauener R.P. Am. J. Pathol. 162 (2003) 1221
48. Chang S.H., Park H., and Dong C. J. Biol. Chem. 281 (2006) 35603
49. Qian Y., Liu C., Hartupee J., Altuntas C.Z., Gulen M.F., Jane-Wit D., Xiao J., Lu Y., Giltiay N., Liu J., Kordula T., Zhang Q.W., Vallance B., Swaidani S., Aronica M., Tuohy V.K., Hamilton T., and Li X. Nat. Immunol. 8 (2007) 247