FK506 suppresses the stimulation of matrix metalloproteinase 13 synthesis by interleukin-1β in rheumatoid synovial fibroblasts

Immunology Letters

Volumn 98, Issue 2, 2005, Pages 194-199

  Migita, Kiyoshi ^a   Miyashita, Taichiro ^a   Maeda, Yumi ^a   Aoyagi, Takahiko ^b   Kawabe, Yojiro ^b   Nakamura, Minoru ^a   Yatsuhashi, Hiroshi ^a   Ishibashi, Hiromi ^a   Eguchi, Katsumi ^c  

^a NATIONAL HOSPITAL ORGANIZATION NAGASAKI MEDICAL CENTER   (Japan)

^b Ureshino Medical Center   (Japan)

^c NAGASAKI UNIVERSITY   (Japan)

Author keywords

FK506; Matrix metalloproteinases; Mitogen activated protein kinases; Rheumatoid arthritis

Indexed keywords

COLLAGENASE 3; ENZYME ANTIBODY; GELATINASE A; INTERLEUKIN 1BETA; STRESS ACTIVATED PROTEIN KINASE; TACROLIMUS; TRANSCRIPTION FACTOR AP 1;

ANTIBODY SPECIFICITY; ARTICLE; CELL LYSATE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SYNTHESIS; FIBROBLAST; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOASSAY; INCUBATION TIME; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIOCYTE; SYNOVIUM; TRANSCRIPTION INITIATION;

EID: 18044386560     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2004.11.014     Document Type: Article

References (26)

1. U. Muller-Ladner, R.E. Gay, and S. Gay Molecular biology of cartilage and bone destruction Curr Opin Rheumatol 10 1998 212 219
2. N.G. Singer, and W.J. McCune Update on immunosuppressive therapy Curr Opin Rheumatol 10 1998 169 173
3. R.B. Gremillion, J.O. Posever, N. Manek, J.P. West, and R.F. van Volen-Hoven Tacrolimus (FK506) in the treatment of severe, refractory rheumatoid arthritis: initial experience in 12 patients J Rheumatol 26 1999 2332 2336
4. D.E. Furst, K. Saag, M.R. Fleischmann, Y. Sherrer, J.A. Block, T. Schnitzer, J. Rutstein, A. Baldassare, J. Kaine, L. Calabrese, F. Dietz, M. Sack, R.G. Senter, C. Wiesenhutter, M. Schiff, C.M. Stein, Y. Satoi, A. Matsumoto, J. Caldwell, R.E. Harris, L.W. Moreland, E. Hurd, D. Yocum, and D.A. Stamler Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate Arthritis Rheum 46 2002 2020 2028
5. D.E. Yocum, D.E. Furst, J.L. Kaine, A.R. Baldassare, J.T. Stevenson, M.A. Borton, L.J. Mengle-Gaw, B.D. Schwartz, W. Wisemandle, Q.A. Mekki Tcrolimus Rheumatoid Arthritis Study Group Efficacy and safety of tacrolimus in patients with rheumatoid arthritis: a double-blind trial Arthritis Rheum 48 2003 3328 3337
6. J.M. Kremer, J.S. Habros, K.S. Kolba, J.L. Kaine, M.A. Borton, L.J. Mengle-Gaw, B.D. Schwartz, W. Wisemandle, Q.A. Mekki Tcrolimus Methotrexate Arthritis Study Group Tacrolimus in rheumatoid arthritis patients receiving concomitant methotrexate: a six-month, open-label study Arthritis Rheum 48 2003 2763 2768
7. H. Kondo, T. Abe, H. Hashimoto, S. Uchida, S. Irimajiri, M. Hara, and S. Sugawara Efficacy and safety of tacrolimus (FK506) in treatment of rheumatoid arthritis: a randomized, double blind, placebo controlled dose-finding study J Rheumatol 31 2004 243 251
8. J. Liu FK506 and cyclosporin, molecular probes for studying intracellular signal transduction Immunol Today 14 1993 290 295
9. A. Rao NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes Immunol Today 15 1994 274 281
10. D.A. Fox The role of T cells in the pathogenesis of rheumatoid arthritis Arthritis Rheum 40 1997 598 609
11. U. Muller-Ladner Molecular and cellular interactions in rheumatoid synovium Curr Opin Rheumatol 8 1996 210 220
12. T. Aoyama, S. Suehiro, H. Hirai, T. Shibata, M. Yoshiyama, T. Omura, S. Kim, and H. Kinoshita Effects of FK506 on acute allograft rejection in transplanted rat heart: the role of mitogen-activated protein kinases, AP-1 and NF-kappaB Osaka City Med J 49 2003 1 10
13. G.L. Johnson, and R. Lapadat Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases Science 298 2002 1911 1912
14. Z. Han, D.L. Boyle, L. Chang, B. Bennett, M. Karin, L. Yang, A.M. Manning, and G.S. Firestein c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis J Clin Invest 108 2001 73 81
15. A.W. Thomson, and T.E. Starzl New immunosuppressive drugs: mechanistic insights and potential therapeutic advances Immunol Rev 136 1993 71 98
16. D.E. Yocum Cyclosporin, FK506, rapamycin, and other immunomodulators Rheum Dis Clin North Am 22 1996 133 154
17. J. Clardy The chemistry of signal trnasduction Proc Nat Acad Sci USA 92 1995 56 61
18. A.L. Whitmarsh, and R.J. Davis Transcriptional factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways J Mol Med 74 1996 589 607
19. A. Minden, A. Lin, T. Smeal, B. Derijard, M. Cobb, R. Davie, and M. Karin c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated kinases Mol Cel Biol 14 1994 6683 6688
20. M. Bond, A.H. Baker, and A.C. Newby Nuclear factor kappaB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabbit dermal fibroblasts Biochem Biophys Res Commun 264 1999 561 567
21. M.L. Cho, C.S. Cho, S.Y. Min, S.H. Kim, S.S. Lee, W.U. Kim, D.J. Min, J.K. Min, J. Youn, S.Y. Hwang, S.H. Park, and H.Y. Kim Cyclosporine inhibition of vascular endothelial growth factor production in rheumatoid synovial fibroblasts Arthritis Rheum 46 2002 1202 1209
22. L.J. De Windt, H.W. Lim, S. Haq, T. Force, and J.D. Molkentin Calcineurin promotes protein kinase C and c-Jun NH2-terminal kinase activation in the heart Cross-talk between cardiac hypertrophic signaling pathways J Biol Chem 275 2000 13571 13579
23. Y. Okada, H. Nagase, and E.D. Harris Matrix metalloproteinases-1, -2, and -3 from rheumatoid synovial cells and sufficient to destroy joints J Rheumatol 14 1987 41 42
24. T. Sorsa, Y.T. Konttinen, O. Lindy, C. Ritchlin, H. Saari, K. Suomalainen, K.K. Eklund, and S. Santavirta Collagenase in synovitis of rheumatoid arthritis Semin Arthritis Rheum 22 1992 44 53
25. M.P. Vincenti, and C.E. Brinckerhoff Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcriptional factors Arhtritis Res 4 2002 157 164
26. J.A. Mengshol, M.P. Vincenti, C.I. Coon, A. Barchowsky, and C.E. Brinckerhoff Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase and nuclear factor kappa B: differential regulation of collagenase 1 and collagenase 3 Arthritis Rheum 43 2000 801 811