-
1
-
-
11844254414
-
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy
-
Jain R.K. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307 (2005) 58-62
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
3
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P., and Jain R.K. Angiogenesis in cancer and other diseases. Nature 407 (2000) 249-257
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
4
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: role of the HIF system
-
Pugh C.W., and Ratcliffe P.J. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat. Med. 9 (2003) 677-684
-
(2003)
Nat. Med.
, vol.9
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
5
-
-
0035160312
-
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
-
Lyden D., Hattori K., Dias S., Costa C., Blaikie P., Butros L., Chadburn A., Heissig B., Marks W., Witte L., Wu Y., Hicklin D., Zhu Z., Hackett N.R., Crystal R.G., Moore M.A., Hajjar K.A., Manova K., Benezra R., and Rafii S. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat. Med. 7 (2001) 1194-1201
-
(2001)
Nat. Med.
, vol.7
, pp. 1194-1201
-
-
Lyden, D.1
Hattori, K.2
Dias, S.3
Costa, C.4
Blaikie, P.5
Butros, L.6
Chadburn, A.7
Heissig, B.8
Marks, W.9
Witte, L.10
Wu, Y.11
Hicklin, D.12
Zhu, Z.13
Hackett, N.R.14
Crystal, R.G.15
Moore, M.A.16
Hajjar, K.A.17
Manova, K.18
Benezra, R.19
Rafii, S.20
more..
-
6
-
-
0034979159
-
Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis
-
Dor Y., Porat R., and Keshet E. Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis. Am. J. Physiol., Cell Physiol. 280 (2001) C1367-C1374
-
(2001)
Am. J. Physiol., Cell Physiol.
, vol.280
-
-
Dor, Y.1
Porat, R.2
Keshet, E.3
-
7
-
-
0036780251
-
Clinical translation of angiogenesis inhibitors
-
Kerbel R., and Folkman J. Clinical translation of angiogenesis inhibitors. Nat. Rev., Cancer 2 (2002) 727-739
-
(2002)
Nat. Rev., Cancer
, vol.2
, pp. 727-739
-
-
Kerbel, R.1
Folkman, J.2
-
8
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers G., and Benjamin L.E. Tumorigenesis and the angiogenic switch. Nat. Rev., Cancer 3 (2003) 401-410
-
(2003)
Nat. Rev., Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
9
-
-
0034161989
-
Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies
-
Eberhard A., Kahlert S., Goede V., Hemmerlein B., Plate K.H., and Augustin H.G. Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies. Cancer Res. 60 (2000) 1388-1393
-
(2000)
Cancer Res.
, vol.60
, pp. 1388-1393
-
-
Eberhard, A.1
Kahlert, S.2
Goede, V.3
Hemmerlein, B.4
Plate, K.H.5
Augustin, H.G.6
-
10
-
-
0032952010
-
Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
-
Benjamin L.E., Golijanin D., Itin A., Pode D., and Keshet E. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J. Clin. Invest. 103 (1999) 159-165
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 159-165
-
-
Benjamin, L.E.1
Golijanin, D.2
Itin, A.3
Pode, D.4
Keshet, E.5
-
11
-
-
0036124520
-
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
-
Morikawa S., Baluk P., Kaidoh T., Haskell A., Jain R.K., and McDonald D.M. Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 160 (2002) 985-1000
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 985-1000
-
-
Morikawa, S.1
Baluk, P.2
Kaidoh, T.3
Haskell, A.4
Jain, R.K.5
McDonald, D.M.6
-
12
-
-
0035700693
-
Clinical relevance of intermittent tumour blood flow
-
Dur R.E., and Aquino-Parsons C. Clinical relevance of intermittent tumour blood flow. Acta Oncol. 40 (2001) 929-936
-
(2001)
Acta Oncol.
, vol.40
, pp. 929-936
-
-
Dur, R.E.1
Aquino-Parsons, C.2
-
13
-
-
0035682917
-
Non-constant tumour blood flow-implications for therapy
-
Dur R.E., and Aquino-Parsons C. Non-constant tumour blood flow-implications for therapy. Acta Oncol. 40 (2001) 862-869
-
(2001)
Acta Oncol.
, vol.40
, pp. 862-869
-
-
Dur, R.E.1
Aquino-Parsons, C.2
-
14
-
-
4344707313
-
Quantifying transient hypoxia in human tumor xenografts by flow cytometry
-
Bennewith K.L., and Durand R.E. Quantifying transient hypoxia in human tumor xenografts by flow cytometry. Cancer Res. 64 (2004) 6183-6189
-
(2004)
Cancer Res.
, vol.64
, pp. 6183-6189
-
-
Bennewith, K.L.1
Durand, R.E.2
-
15
-
-
0034660890
-
Fractals and cancer
-
Baish J.W., and Jain R.K. Fractals and cancer. Cancer Res. 60 (2000) 3683-3688
-
(2000)
Cancer Res.
, vol.60
, pp. 3683-3688
-
-
Baish, J.W.1
Jain, R.K.2
-
16
-
-
1542320497
-
Pathology: cancer cells compress intratumour vessels
-
Padera T.P., Stoll B.R., Tooredman J.B., Capen D., di Tomaso E., and Jain R.K. Pathology: cancer cells compress intratumour vessels. Nature 427 (2004) 695
-
(2004)
Nature
, vol.427
, pp. 695
-
-
Padera, T.P.1
Stoll, B.R.2
Tooredman, J.B.3
Capen, D.4
di Tomaso, E.5
Jain, R.K.6
-
17
-
-
0036320934
-
Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression
-
Wenger R.H. Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression. FASEB J. 16 (2002) 1151-1162
-
(2002)
FASEB J.
, vol.16
, pp. 1151-1162
-
-
Wenger, R.H.1
-
18
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang G.L., Jiang B.H., Rue E.A., and Semenza G.L. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 5510-5514
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
19
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
Wang G.L., and Semenza G.L. Purification and characterization of hypoxia-inducible factor 1. J. Biol. Chem. 270 (1995) 1230-1237
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
20
-
-
0030961006
-
Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
-
Salceda S., and Caro J. Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J. Biol. Chem. 272 (1997) 22642-22647
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22642-22647
-
-
Salceda, S.1
Caro, J.2
-
21
-
-
0035812772
-
HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus
-
Semenza G.L. HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell 107 (2001) 1-3
-
(2001)
Cell
, vol.107
, pp. 1-3
-
-
Semenza, G.L.1
-
22
-
-
0035917313
-
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
-
Ivan M., Kondo K., Yang H., Kim W., Valiando J., Ohh M., Salic A., Asara J.M., Lane W.S., and Kaelin Jr. W.G. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 292 (2001) 464-468
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
23
-
-
0034682783
-
Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
-
Cockman M.E., Masson N., Mole D.R., Jaakkola P., Chang G.W., Clifford S.C., Maher E.R., Pugh C.W., Ratcliffe P.J., and Maxwell P.H. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. J. Biol. Chem. 275 (2000) 25733-25741
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25733-25741
-
-
Cockman, M.E.1
Masson, N.2
Mole, D.R.3
Jaakkola, P.4
Chang, G.W.5
Clifford, S.C.6
Maher, E.R.7
Pugh, C.W.8
Ratcliffe, P.J.9
Maxwell, P.H.10
-
24
-
-
0035917808
-
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
Jaakkola P., Mole D.R., Tian Y.M., Wilson M.I., Gielbert J., Gaskell S.J., Kriegsheim A., Hebestreit H.F., Mukherji M., Schofield C.J., Maxwell P.H., Pugh C.W., and Ratcliffe P.J. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292 (2001) 468-472
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
25
-
-
0035347260
-
Induction of HIF-1alpha in response to hypoxia is instantaneous
-
Jewell U.R., Kvietikova I., Scheid A., Bauer C., Wenger R.H., and Gassmann M. Induction of HIF-1alpha in response to hypoxia is instantaneous. FASEB J. 15 (2001) 1312-1314
-
(2001)
FASEB J.
, vol.15
, pp. 1312-1314
-
-
Jewell, U.R.1
Kvietikova, I.2
Scheid, A.3
Bauer, C.4
Wenger, R.H.5
Gassmann, M.6
-
26
-
-
0029944965
-
Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
-
Jiang B.H., Rue E., Wang G.L., Roe R., and Semenza G.L. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J. Biol. Chem. 271 (1996) 17771-17778
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17771-17778
-
-
Jiang, B.H.1
Rue, E.2
Wang, G.L.3
Roe, R.4
Semenza, G.L.5
-
27
-
-
0034107952
-
Mammalian oxygen sensing, signalling and gene regulation
-
Wenger R.H. Mammalian oxygen sensing, signalling and gene regulation. J. Exp. Biol. 203 (2000) 1253-1263
-
(2000)
J. Exp. Biol.
, vol.203
, pp. 1253-1263
-
-
Wenger, R.H.1
-
28
-
-
0035694958
-
Intermittent blood flow in solid tumours-An under-appreciated source of 'drug resistance'
-
Durand R.E. Intermittent blood flow in solid tumours-An under-appreciated source of 'drug resistance'. Cancer Metastasis Rev. 20 (2001) 57-61
-
(2001)
Cancer Metastasis Rev.
, vol.20
, pp. 57-61
-
-
Durand, R.E.1
-
29
-
-
0032756201
-
Inducible repair and the two forms of tumour hypoxia-time for a paradigm shift
-
Denekamp J., and Dasu A. Inducible repair and the two forms of tumour hypoxia-time for a paradigm shift. Acta Oncol. 38 (1999) 903-918
-
(1999)
Acta Oncol.
, vol.38
, pp. 903-918
-
-
Denekamp, J.1
Dasu, A.2
-
30
-
-
0029024240
-
Temporal heterogeneity in microregional erythrocyte flux in experimental solid tumours
-
Chaplin D.J., and Hill S.A. Temporal heterogeneity in microregional erythrocyte flux in experimental solid tumours. Br. J. Cancer 71 (1995) 1210-1213
-
(1995)
Br. J. Cancer
, vol.71
, pp. 1210-1213
-
-
Chaplin, D.J.1
Hill, S.A.2
-
32
-
-
8944246794
-
Microregional blood flow in murine and human tumours assessed using laser Doppler microprobes
-
Hill S.A., Pigott K.H., Saunders M.I., Powell M.E., Arnold S., Obeid A., Ward G., Leahy M., Hoskin P.J., and Chaplin D.J. Microregional blood flow in murine and human tumours assessed using laser Doppler microprobes. Br. J. Cancer., Suppl. 27 (1996) S260-S263
-
(1996)
Br. J. Cancer., Suppl.
, vol.27
-
-
Hill, S.A.1
Pigott, K.H.2
Saunders, M.I.3
Powell, M.E.4
Arnold, S.5
Obeid, A.6
Ward, G.7
Leahy, M.8
Hoskin, P.J.9
Chaplin, D.J.10
-
33
-
-
0030200651
-
Microregional fluctuations in perfusion within human tumours detected using laser Doppler flowmetry
-
Pigott K.H., Hill S.A., Chaplin D.J., and Saunders M.I. Microregional fluctuations in perfusion within human tumours detected using laser Doppler flowmetry. Radiother. Oncol. 40 (1996) 45-50
-
(1996)
Radiother. Oncol.
, vol.40
, pp. 45-50
-
-
Pigott, K.H.1
Hill, S.A.2
Chaplin, D.J.3
Saunders, M.I.4
-
34
-
-
33846204728
-
Preconditioning of the tumor vasculature and tumor cells by intermittent hypoxia: implications for anticancer therapies
-
Martinive P., Defresne F., Bouzin C., Saliez J., Lair F., Gregoire V., Michiels C., Dessy C., and Feron O. Preconditioning of the tumor vasculature and tumor cells by intermittent hypoxia: implications for anticancer therapies. Cancer Res. 66 (2006) 11736-11744
-
(2006)
Cancer Res.
, vol.66
, pp. 11736-11744
-
-
Martinive, P.1
Defresne, F.2
Bouzin, C.3
Saliez, J.4
Lair, F.5
Gregoire, V.6
Michiels, C.7
Dessy, C.8
Feron, O.9
-
35
-
-
0001637870
-
Permanent cell line expressing human factor VIII-related antigen established by hybridization
-
Edgell C.J., McDonald C.C., and Graham J.B. Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc. Natl. Acad. Sci. U. S. A. 80 (1983) 3734-3737
-
(1983)
Proc. Natl. Acad. Sci. U. S. A.
, vol.80
, pp. 3734-3737
-
-
Edgell, C.J.1
McDonald, C.C.2
Graham, J.B.3
-
36
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell P.H., Wiesener M.S., Chang G.W., Clifford S.C., Vaux E.C., Cockman M.E., Wykoff C.C., Pugh C.W., Maher E.R., and Ratcliffe P.J. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399 (1999) 271-275
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
37
-
-
0033981845
-
ERK activation upon hypoxia: involvement in HIF-1 activation
-
Minet E., Arnould T., Michel G., Roland I., Mottet D., Raes M., Remacle J., and Michiels C. ERK activation upon hypoxia: involvement in HIF-1 activation. FEBS Lett. 468 (2000) 53-58
-
(2000)
FEBS Lett.
, vol.468
, pp. 53-58
-
-
Minet, E.1
Arnould, T.2
Michel, G.3
Roland, I.4
Mottet, D.5
Raes, M.6
Remacle, J.7
Michiels, C.8
-
38
-
-
0043234256
-
Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells
-
Mottet D., Dumont V., Deccache Y., Demazy C., Ninane N., Raes M., and Michiels C. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells. J. Biol. Chem. 278 (2003) 31277-31285
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31277-31285
-
-
Mottet, D.1
Dumont, V.2
Deccache, Y.3
Demazy, C.4
Ninane, N.5
Raes, M.6
Michiels, C.7
-
39
-
-
17844364429
-
Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I
-
Treins C., Giorgetti-Peraldi S., Murdaca J., Monthouel-Kartmann M.N., and Van Obberghen E. Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I. Mol. Endocrinol. 19 (2005) 1304-1317
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 1304-1317
-
-
Treins, C.1
Giorgetti-Peraldi, S.2
Murdaca, J.3
Monthouel-Kartmann, M.N.4
Van Obberghen, E.5
-
40
-
-
0032725554
-
p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1
-
Richard D.E., Berra E., Gothie E., Roux D., and Pouyssegur J. p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. J. Biol. Chem. 274 (1999) 32631-32637
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32631-32637
-
-
Richard, D.E.1
Berra, E.2
Gothie, E.3
Roux, D.4
Pouyssegur, J.5
-
41
-
-
33845403070
-
Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha
-
Mylonis I., Chachami G., Samiotaki M., Panayotou G., Paraskeva E., Kalousi A., Georgatsou E., Bonanou S., and Simos G. Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha. J. Biol. Chem. 281 (2006) 33095-33106
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 33095-33106
-
-
Mylonis, I.1
Chachami, G.2
Samiotaki, M.3
Panayotou, G.4
Paraskeva, E.5
Kalousi, A.6
Georgatsou, E.7
Bonanou, S.8
Simos, G.9
-
42
-
-
1842691021
-
PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation
-
Zhou J., Schmid T., Frank R., and Brune B. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation. J. Biol. Chem. 279 (2004) 13506-13513
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13506-13513
-
-
Zhou, J.1
Schmid, T.2
Frank, R.3
Brune, B.4
-
43
-
-
0037177867
-
Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription
-
Arsham A.M., Plas D.R., Thompson C.B., and Simon M.C. Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription. J. Biol. Chem. 277 (2002) 15162-15170
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15162-15170
-
-
Arsham, A.M.1
Plas, D.R.2
Thompson, C.B.3
Simon, M.C.4
-
44
-
-
33646560932
-
Erythropoietin production: Molecular mechanisms of the antagonistic actions of cyclic adenosine monophosphate and interleukin-1
-
Batmunkh C., Krajewski J., Jelkmann W., and Hellwig-Burgel T. Erythropoietin production: Molecular mechanisms of the antagonistic actions of cyclic adenosine monophosphate and interleukin-1. FEBS Lett. 580 (2006) 3153-3160
-
(2006)
FEBS Lett.
, vol.580
, pp. 3153-3160
-
-
Batmunkh, C.1
Krajewski, J.2
Jelkmann, W.3
Hellwig-Burgel, T.4
-
45
-
-
0028891906
-
The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site
-
Kvietikova I., Wenger R.H., Marti H.H., and Gassmann M. The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site. Nucleic Acids Res. 23 (1995) 4542-4550
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4542-4550
-
-
Kvietikova, I.1
Wenger, R.H.2
Marti, H.H.3
Gassmann, M.4
-
46
-
-
0027959825
-
Hypoxia and cobalt stimulate lactate dehydrogenase (LDH) activity in vascular smooth muscle cells
-
Marti H.H., Jung H.H., Pfeilschifter J., and Bauer C. Hypoxia and cobalt stimulate lactate dehydrogenase (LDH) activity in vascular smooth muscle cells. Pflugers Arch. 429 (1994) 216-222
-
(1994)
Pflugers Arch.
, vol.429
, pp. 216-222
-
-
Marti, H.H.1
Jung, H.H.2
Pfeilschifter, J.3
Bauer, C.4
-
47
-
-
33644867986
-
Protein kinase A-mediated phosphorylation modulates cytochrome C oxidase function and augments hypoxia and myocardial ischemia related injury
-
Prabu S.K., Anandatheerthavarada H.K., Raza H., Srinivasan S., Spear J.F., and Avadhani N.G. Protein kinase A-mediated phosphorylation modulates cytochrome C oxidase function and augments hypoxia and myocardial ischemia related injury. J. Biol. Chem. 281 (2005) 2061-2070
-
(2005)
J. Biol. Chem.
, vol.281
, pp. 2061-2070
-
-
Prabu, S.K.1
Anandatheerthavarada, H.K.2
Raza, H.3
Srinivasan, S.4
Spear, J.F.5
Avadhani, N.G.6
-
48
-
-
29644440060
-
Enhanced phosphorylation of cyclic AMP response element binding protein in the brain of mice following repetitive hypoxic exposure
-
Gao Y., Gao G., Long C., Han S., Zu P., Fang L., and Li J. Enhanced phosphorylation of cyclic AMP response element binding protein in the brain of mice following repetitive hypoxic exposure. Biochem. Biophys. Res. Commun. 340 (2006) 661-667
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.340
, pp. 661-667
-
-
Gao, Y.1
Gao, G.2
Long, C.3
Han, S.4
Zu, P.5
Fang, L.6
Li, J.7
-
49
-
-
0029884640
-
Hypoxia regulates vascular endothelial growth factor receptor KDR/Flk gene expression through adenosine A2 receptors in retinal capillary endothelial cells
-
Takagi H., King G.L., Ferrara N., and Aiello L.P. Hypoxia regulates vascular endothelial growth factor receptor KDR/Flk gene expression through adenosine A2 receptors in retinal capillary endothelial cells. Investig. Ophthalmol. Vis. Sci. 37 (1996) 1311-1321
-
(1996)
Investig. Ophthalmol. Vis. Sci.
, vol.37
, pp. 1311-1321
-
-
Takagi, H.1
King, G.L.2
Ferrara, N.3
Aiello, L.P.4
-
50
-
-
0029840035
-
Adenosine mediates hypoxic induction of vascular endothelial growth factor in retinal pericytes and endothelial cells
-
Takagi H., King G.L., Robinson G.S., Ferrara N., and Aiello L.P. Adenosine mediates hypoxic induction of vascular endothelial growth factor in retinal pericytes and endothelial cells. Investig. Ophthalmol. Vis. Sci. 37 (1996) 2165-2176
-
(1996)
Investig. Ophthalmol. Vis. Sci.
, vol.37
, pp. 2165-2176
-
-
Takagi, H.1
King, G.L.2
Robinson, G.S.3
Ferrara, N.4
Aiello, L.P.5
-
51
-
-
0034128083
-
Adenosine and muscle vasodilatation in acute systemic hypoxia
-
Marshall J.M. Adenosine and muscle vasodilatation in acute systemic hypoxia. Acta Physiol. Scand. 168 (2000) 561-573
-
(2000)
Acta Physiol. Scand.
, vol.168
, pp. 561-573
-
-
Marshall, J.M.1
-
52
-
-
22144464451
-
Equilibrative nucleoside transporter 1 expression is downregulated by hypoxia in human umbilical vein endothelium
-
Casanello P., Torres A., Sanhueza F., Gonzalez M., Farias M., Gallardo V., Pastor-Anglada M., San Martin R., and Sobrevia L. Equilibrative nucleoside transporter 1 expression is downregulated by hypoxia in human umbilical vein endothelium. Circ. Res. 97 (2005) 16-24
-
(2005)
Circ. Res.
, vol.97
, pp. 16-24
-
-
Casanello, P.1
Torres, A.2
Sanhueza, F.3
Gonzalez, M.4
Farias, M.5
Gallardo, V.6
Pastor-Anglada, M.7
San Martin, R.8
Sobrevia, L.9
-
53
-
-
23044510839
-
Growth regulation of the vascular system: an emerging role for adenosine
-
Adair T.H. Growth regulation of the vascular system: an emerging role for adenosine. Am. J. Physiol., Regul. Integr. Comp. Physiol. 289 (2005) R283-R296
-
(2005)
Am. J. Physiol., Regul. Integr. Comp. Physiol.
, vol.289
-
-
Adair, T.H.1
-
54
-
-
0028183014
-
Nomenclature and classification of purinoceptors
-
Fredholm B.B., Abbracchio M.P., Burnstock G., Daly J.W., Harden T.K., Jacobson K.A., Leff P., and Williams M. Nomenclature and classification of purinoceptors. Pharmacol. Rev. 46 (1994) 143-156
-
(1994)
Pharmacol. Rev.
, vol.46
, pp. 143-156
-
-
Fredholm, B.B.1
Abbracchio, M.P.2
Burnstock, G.3
Daly, J.W.4
Harden, T.K.5
Jacobson, K.A.6
Leff, P.7
Williams, M.8
-
55
-
-
0029921939
-
Adenosine physiology and pharmacology: how about A2 receptors?
-
Daval J.L., Nicolas F., and Doriat J.F. Adenosine physiology and pharmacology: how about A2 receptors?. Pharmacol. Ther. 71 (1996) 325-335
-
(1996)
Pharmacol. Ther.
, vol.71
, pp. 325-335
-
-
Daval, J.L.1
Nicolas, F.2
Doriat, J.F.3
-
56
-
-
0027478599
-
Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia
-
Michiels C., Arnould T., Knott I., Dieu M., and Remacle J. Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia. Am. J. Physiol. 264 (1993) C866-C874
-
(1993)
Am. J. Physiol.
, vol.264
-
-
Michiels, C.1
Arnould, T.2
Knott, I.3
Dieu, M.4
Remacle, J.5
-
57
-
-
0037081745
-
Identification of the phospholipase A(2) isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: limits of phospholipase A(2) inhibitors
-
Michiels C., Renard P., Bouaziz N., Heck N., Eliaers F., Ninane N., Quarck R., Holvoet P., and Raes M. Identification of the phospholipase A(2) isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: limits of phospholipase A(2) inhibitors. Biochem. Pharmacol. 63 (2002) 321-332
-
(2002)
Biochem. Pharmacol.
, vol.63
, pp. 321-332
-
-
Michiels, C.1
Renard, P.2
Bouaziz, N.3
Heck, N.4
Eliaers, F.5
Ninane, N.6
Quarck, R.7
Holvoet, P.8
Raes, M.9
-
59
-
-
0036794517
-
Interactions of adenosine, prostaglandins and nitric oxide in hypoxia-induced vasodilatation: in vivo and in vitro studies
-
Ray C.J., Abbas M.R., Coney A.M., and Marshall J.M. Interactions of adenosine, prostaglandins and nitric oxide in hypoxia-induced vasodilatation: in vivo and in vitro studies. J. Physiol. 544 (2002) 195-209
-
(2002)
J. Physiol.
, vol.544
, pp. 195-209
-
-
Ray, C.J.1
Abbas, M.R.2
Coney, A.M.3
Marshall, J.M.4
-
60
-
-
33645990346
-
The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium
-
Ray C.J., and Marshall J.M. The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium. J. Physiol. 570 (2006) 85-96
-
(2006)
J. Physiol.
, vol.570
, pp. 85-96
-
-
Ray, C.J.1
Marshall, J.M.2
-
61
-
-
3242740249
-
Role of oxidative stress in intermittent hypoxia-induced immediate early gene activation in rat PC12 cells
-
Yuan G., Adhikary G., McCormick A.A., Holcroft J.J., Kumar G.K., and Prabhakar N.R. Role of oxidative stress in intermittent hypoxia-induced immediate early gene activation in rat PC12 cells. J. Physiol. 557 (2004) 773-783
-
(2004)
J. Physiol.
, vol.557
, pp. 773-783
-
-
Yuan, G.1
Adhikary, G.2
McCormick, A.A.3
Holcroft, J.J.4
Kumar, G.K.5
Prabhakar, N.R.6
-
62
-
-
33847267684
-
A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation
-
Ryan S., McNicholas W.T., and Taylor C.T. A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation. Biochem. Biophys. Res. Commun. 355 (2007) 728-733
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.355
, pp. 728-733
-
-
Ryan, S.1
McNicholas, W.T.2
Taylor, C.T.3
-
63
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics
-
Zhong H., Chiles K., Feldser D., Laughner E., Hanrahan C., Georgescu M.M., Simons J.W., and Semenza G.L. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res. 60 (2000) 1541-1545
-
(2000)
Cancer Res.
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
Laughner, E.4
Hanrahan, C.5
Georgescu, M.M.6
Simons, J.W.7
Semenza, G.L.8
-
64
-
-
18744375998
-
Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation
-
Jeong J.W., Bae M.K., Ahn M.Y., Kim S.H., Sohn T.K., Bae M.H., Yoo M.A., Song E.J., Lee K.J., and Kim K.W. Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell 111 (2002) 709-720
-
(2002)
Cell
, vol.111
, pp. 709-720
-
-
Jeong, J.W.1
Bae, M.K.2
Ahn, M.Y.3
Kim, S.H.4
Sohn, T.K.5
Bae, M.H.6
Yoo, M.A.7
Song, E.J.8
Lee, K.J.9
Kim, K.W.10
-
65
-
-
34047272690
-
Regulation of HIF-1alpha stability through S-nitrosylation
-
Li F., Sonveaux P., Rabbani Z.N., Liu S., Yan B., Huang Q., Vujaskovic Z., Dewhirst M.W., and Li C.Y. Regulation of HIF-1alpha stability through S-nitrosylation. Mol. Cell 26 (2007) 63-74
-
(2007)
Mol. Cell
, vol.26
, pp. 63-74
-
-
Li, F.1
Sonveaux, P.2
Rabbani, Z.N.3
Liu, S.4
Yan, B.5
Huang, Q.6
Vujaskovic, Z.7
Dewhirst, M.W.8
Li, C.Y.9
-
66
-
-
0037097861
-
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
-
Lando D., Peet D.J., Gorman J.J., Whelan D.A., Whitelaw M.L., and Bruick R.K. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev. 16 (2002) 1466-1471
-
(2002)
Genes Dev.
, vol.16
, pp. 1466-1471
-
-
Lando, D.1
Peet, D.J.2
Gorman, J.J.3
Whelan, D.A.4
Whitelaw, M.L.5
Bruick, R.K.6
-
67
-
-
0042564792
-
S-nitrosation of Cys-800 of HIF-1alpha protein activates its interaction with p300 and stimulates its transcriptional activity
-
Yasinska I.M., and Sumbayev V.V. S-nitrosation of Cys-800 of HIF-1alpha protein activates its interaction with p300 and stimulates its transcriptional activity. FEBS Lett. 549 (2003) 105-109
-
(2003)
FEBS Lett.
, vol.549
, pp. 105-109
-
-
Yasinska, I.M.1
Sumbayev, V.V.2
-
68
-
-
0035855668
-
Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia
-
Suzuki H., Tomida A., and Tsuruo T. Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia. Oncogene 20 (2001) 5779-5788
-
(2001)
Oncogene
, vol.20
, pp. 5779-5788
-
-
Suzuki, H.1
Tomida, A.2
Tsuruo, T.3
-
69
-
-
0022592496
-
Changes in intracellular pH induced by hyperthermia and hypoxia
-
Vexler A.M., and Litinskaya L.L. Changes in intracellular pH induced by hyperthermia and hypoxia. Int. J. Hypertherm. 2 (1986) 75-81
-
(1986)
Int. J. Hypertherm.
, vol.2
, pp. 75-81
-
-
Vexler, A.M.1
Litinskaya, L.L.2
-
70
-
-
33644873854
-
Antiangiogenic agent SU6668 suppresses the tumor growth of xenografted A-431 cells
-
Nakamura T., Ozawa S., Kitagawa Y., Ueda M., Kubota T., and Kitajima M. Antiangiogenic agent SU6668 suppresses the tumor growth of xenografted A-431 cells. Oncol. Rep. 15 (2006) 79-83
-
(2006)
Oncol. Rep.
, vol.15
, pp. 79-83
-
-
Nakamura, T.1
Ozawa, S.2
Kitagawa, Y.3
Ueda, M.4
Kubota, T.5
Kitajima, M.6
|