Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis

American Journal of Physiology - Cell Physiology

Volumn 280, Issue 6 49-6, 2001, Pages

  Dor, Y ^a   Porat, R ^a   Keshet, E ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Angiogenesis; Hyperoxia; Hypoxia; Vessel regression

Indexed keywords

MESSENGER RNA; OXYGEN; VASCULOTROPIN;

5' UNTRANSLATED REGION; ANGIOGENESIS; BLOOD VESSEL OCCLUSION; ENDOTHELIUM CELL; FEEDBACK SYSTEM; GENETIC TRANSCRIPTION; HOMEOSTASIS; HUMAN; HYPEROXIA; HYPOGLYCEMIA; HYPOXIA; MICROVASCULARIZATION; NEOVASCULARIZATION (PATHOLOGY); OXYGEN CONSUMPTION; PRIORITY JOURNAL; REVIEW; STRESS; TISSUE METABOLISM; TISSUE OXYGENATION; TISSUE PERFUSION;

EID: 0034979159     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2001.280.6.c1367     Document Type: Review

References (74)

1. Multilineage embryonic hematopoiesis requires hypoxic ARNT activity
2. VEGF acts as a survival factor for newly-formed retinal vessels: Implications for retinopathy of prematurity
3. Retinal vascularization in health and disease
4. Oxygen and the growth and development of retinal vessels
5. Vascular development: Cellular and molecular regulation
6. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
7. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
8. Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal
9. Complex experience promotes capillary formation in young rat visual cortex
10. The pathophysiology of collateral circulation
11. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
12. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
13. Role of tissue factor in embryonic blood vessel development
14. Abnormal development of the rat heart during prenatal hypoxic stress
15. Microvascular pericytes: A review of their morphological and functional characteristics
16. Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization
17. Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
18. Heterogeneity of angiogenesis and blood vessel maturation in human tumors: Implications for antiangiogenic tumor therapies
19. Postnatal remodeling of the leptomeningeal vascular network as assessed by intravital fluorescence video-microscopy in the rat
20. The role of vascular endothelial growth factor in angiogenesis
21. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
22. Vascular endothelial growth factor is essential for corpus luteum angiogenesis
23. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
24. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
25. Retinopathy of prematurity-induced blindness: Birth weight-specific survival and the new epidemic
26. Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis
27. Embryonic oxygen deficiency - A physiological approach to analysis of teratological mechanisms
28. Vascular endothelial growth factor-induced migration of vascular smooth muscle cells in vitro
29. Exercise-induced expression of angiogenesis-related transcription and growth factors in human skeletal muscle
30. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
31. Studies on inflammation and wound healing: Angiogenesis and collagen synthesis stimulated in vivo by resident and activated wound macrophages
32. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
33. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo
34. Oxygen tension regulates the expression of angiogenesis factor by macrophages
35. Regulation of wound-healing angiogenesis-effect of oxygen gradients and inspired oxygen concentration
36. Mice deficient for PDGF-B show renal, cardiovascular, and hematological abnormalities
37. Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel-Lindau protein
38. Post-transcriptional regulation of vascular endothelial growth factor by hypoxia
39. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
40. Gene therapy for myocardial angiogenesis
41. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
42. Prevalence of congenital cardiac anomalies at high altitude
43. The mode of development of the vascular system of the retina, with some observations on its significance for certain retinal diseases
44. Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells
45. Vascular endothelial growth factor is a potential turnout angiogenesis factor in human gliomas in vivo
46. The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells
47. Human VEGF gene expression in skeletal muscle: Effect of acute normoxic and hypoxic exercise
48. Exercise adaptation attenuates VEGF gene expression in human skeletal muscle
49. Vasculogenesis
50. Age-dependent deficit in VEGF expression is associated with reduced hypoxia-inducible factor 1 activity
51. HIF-1 alpha is required for solid tumor formation and embryonic vascularization
52. Hypoxia-inducible factor-1α is a positive factor in solid tumor growth
53. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
54. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factor-β1-like molecule by plasmin during co-culture
55. Arteriogenesis, the good and bad of it
56. Transcriptional regulation by hypoxia-inducible factor-1
57. Surviving ischemia: Adaptive responses mediated by hypoxia-inducible factor 1
58. Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability
59. Interindividual heterogeneity in the hypoxic regulation of VEGF: Significance for the development of the coronary artery collateral circulation
60. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
61. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
62. Food for starving hearts
63. Thyroid-stimulating hormone promotes the secretion of VEGF in thyroid cancer cell lines
64. Studies on diabetic retinopathy. III. Influence of diabetes on intramural pericytes
65. Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes
66. Translation of VEGF mRNA by internal ribosome entry: Implications for translation under hypoxia
67. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia
68. Arteriolar and capillary remodeling in hypertension
69. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
70. Time course of increased cellular proliferation in collateral arteries after administration of vascular endothelial growth factor in a rabbit model of lower limb vascular insufficiency
71. Vasa vasorum in atherosclerotic coronary arteries: Responses to vasoactive stimuli and regression of atherosclerosis
72. The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells
73. Adaptation to arterial wall hypoxia demonstrated in vivo with oxygen microcathodes
74. Oxygen sensing and signaling: Impact on the regulation of physiologically important genes