Identification of the phospholipase A2 isoforms that contribute to arachidonic acid release in hypoxic endothelial cells: Limits of phospholipase A2 inhibitors

Biochemical Pharmacology

Volumn 63, Issue 2, 2002, Pages 321-332

  Michiels, Carine ^a   Renard, Patricia ^a   Bouaziz, Najat ^a   Heck, Nathalie ^a   Eliaers, François ^a   Ninane, Noëlle ^a   Quarck, Rozenn ^b   Holvoet, Paul ^b   Raes, Martine ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Endothelial cells; Hypoxia; Phospholipase A2; PLA2 inhibitors; Prostaglandins

Indexed keywords

ARACHIDONIC ACID; ARACHIDONYL TRIFLUOROMETHYL KETONE; BROMOENOL LACTONE; CYCLOHEXIMIDE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PROSTAGLANDIN;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; UMBILICAL VEIN;

ARACHIDONIC ACID; ARACHIDONIC ACIDS; CELL HYPOXIA; CELLS, CULTURED; DINOPROST; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HUMANS; ISOENZYMES; NAPHTHALENES; PHOSPHOLIPASES A; PHOSPHORYLCHOLINE; PYRONES;

EID: 0037081745     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00832-2     Document Type: Article

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