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Volumn 94, Issue 6, 1996, Pages 1412-1422

Enhanced thrombolytic and antithrombotic potency of a fibrin-targeted plasminogen activator in baboons

Author keywords

arteriosclerosis; plasminogen activators; thrombolysis; thrombosis

Indexed keywords

ALTEPLASE; FIBRIN ANTIBODY; HEPARIN; RECOMBINANT PLASMINOGEN ACTIVATOR; UROKINASE;

EID: 9544229716     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.94.6.1412     Document Type: Article
Times cited : (39)

References (39)
  • 2
    • 0023835206 scopus 로고
    • Effect of intravenous APSAC on mortality after acute myocardial infarction: Preliminary report of a placebo-controlled clinical trial
    • AIMS Trial Study Group. Effect of intravenous APSAC on mortality after acute myocardial infarction: preliminary report of a placebo-controlled clinical trial. Lancet. 1988;1:545-549.
    • (1988) Lancet , vol.1 , pp. 545-549
  • 3
    • 0022640774 scopus 로고
    • Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction
    • Letter
    • GISSI (Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico). Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet. 1986;1:397. Letter.
    • (1986) Lancet , vol.1 , pp. 397
  • 4
    • 84921620586 scopus 로고
    • Intravenous streptokinase given within 0-4 hours of onset of myocardial infarction reduced mortality in ISIS-2
    • Letter
    • ISIS Steering Committee. Intravenous streptokinase given within 0-4 hours of onset of myocardial infarction reduced mortality in ISIS-2. Lancet. 1987;1:502. Letter.
    • (1987) Lancet , vol.1 , pp. 502
  • 6
    • 0021916187 scopus 로고
    • The Thrombolysis in Myocardial Infarction (TIMI) trial: Phase I findings
    • TIMI Study Group. The Thrombolysis in Myocardial Infarction (TIMI) trial: phase I findings. N Engl J Med. 1985;312:932-936.
    • (1985) N Engl J Med , vol.312 , pp. 932-936
  • 10
    • 0025111362 scopus 로고
    • Thrombolytic activity of a novel plasminogen activator, LY210825, compared with recombinant tissue-type plasminogen activator in a canine model of coronary artery thrombosis
    • Jackson CV, Crowe VG, Craft TJ, Sundboom JL, Grinnell BW, Bobbitt JL, Burck PJ, Quay JF, Smith GF. Thrombolytic activity of a novel plasminogen activator, LY210825, compared with recombinant tissue-type plasminogen activator in a canine model of coronary artery thrombosis. Circulation. 1990;82:1062-1063.
    • (1990) Circulation , vol.82 , pp. 1062-1063
    • Jackson, C.V.1    Crowe, V.G.2    Craft, T.J.3    Sundboom, J.L.4    Grinnell, B.W.5    Bobbitt, J.L.6    Burck, P.J.7    Quay, J.F.8    Smith, G.F.9
  • 11
    • 0026038525 scopus 로고
    • Characterization of a chimeric plasminogen activator consisting of a single-chain Fv fragment derived from a fibrin fragment D-dimer-specific antibody and a truncated single-chain urokinase
    • Holvoet PY, Laroche Y, Lijnen HR, Van Cauwenberge R, Demarsin E, Brouwers E, Matthyssens G, Collen D. Characterization of a chimeric plasminogen activator consisting of a single-chain Fv fragment derived from a fibrin fragment D-dimer-specific antibody and a truncated single-chain urokinase. J Biol Chem. 1991;266:19717-19724.
    • (1991) J Biol Chem , vol.266 , pp. 19717-19724
    • Holvoet, P.Y.1    Laroche, Y.2    Lijnen, H.R.3    Van Cauwenberge, R.4    Demarsin, E.5    Brouwers, E.6    Matthyssens, G.7    Collen, D.8
  • 12
    • 0023830817 scopus 로고
    • Variants of human tissue-type plasminogen activator: Fibrin binding, fibrinolytic, and fibrinogenolytic characterization of genetic variants lacking the fibronectin finger-like and/or the epidermal growth factor domains
    • Larsen GR, Henson K, Blue Y. Variants of human tissue-type plasminogen activator: fibrin binding, fibrinolytic, and fibrinogenolytic characterization of genetic variants lacking the fibronectin finger-like and/or the epidermal growth factor domains. J Biol Chem. 1988;263:1023-1029.
    • (1988) J Biol Chem , vol.263 , pp. 1023-1029
    • Larsen, G.R.1    Henson, K.2    Blue, Y.3
  • 13
    • 0023903090 scopus 로고
    • Biochemical and thrombolytic properties of a low molecular weight form (comprising Leu144 through Leu411) of recombinant single-chain urokinase-type plasminogen activator
    • Lijnen HR, Nelles L, Holmes WE, Collen D. Biochemical and thrombolytic properties of a low molecular weight form (comprising Leu144 through Leu411) of recombinant single-chain urokinase-type plasminogen activator. J Biol Chem. 1988;263:5594-5598.
    • (1988) J Biol Chem , vol.263 , pp. 5594-5598
    • Lijnen, H.R.1    Nelles, L.2    Holmes, W.E.3    Collen, D.4
  • 14
    • 0025231777 scopus 로고
    • Biochemical and functional characterization of human tissue-type plasminogen activator variants obtained by deletion and/or duplication of structural/ functional domains
    • Lijnen HR, Nelles L, Van Hoef B, De Cock F, Collen D. Biochemical and functional characterization of human tissue-type plasminogen activator variants obtained by deletion and/or duplication of structural/ functional domains. J Biol Chem. 1990;265:5677-5683.
    • (1990) J Biol Chem , vol.265 , pp. 5677-5683
    • Lijnen, H.R.1    Nelles, L.2    Van Hoef, B.3    De Cock, F.4    Collen, D.5
  • 16
    • 0023664285 scopus 로고
    • Characterization of recombinant human single chain urokinase-type plasminogen activator mutants produced by site-specific mutagenesis of lysine 158
    • Nelles L, Lijnen HR, Collen D, Holmes WE. Characterization of recombinant human single chain urokinase-type plasminogen activator mutants produced by site-specific mutagenesis of lysine 158. J Biol Chem. 1987;262:5682-5689.
    • (1987) J Biol Chem , vol.262 , pp. 5682-5689
    • Nelles, L.1    Lijnen, H.R.2    Collen, D.3    Holmes, W.E.4
  • 17
    • 0023278835 scopus 로고
    • Characterization of a fusion protein consisting of amino acids 1 to 263 of tissue-type plasminogen activator and amino acids 144 to 411 of urokinase-type plasminogen activator
    • Nelles L, Lijnen HR, Collen D, Holmes WE. Characterization of a fusion protein consisting of amino acids 1 to 263 of tissue-type plasminogen activator and amino acids 144 to 411 of urokinase-type plasminogen activator. J Biol Chem. 1987;262:10855-10862.
    • (1987) J Biol Chem , vol.262 , pp. 10855-10862
    • Nelles, L.1    Lijnen, H.R.2    Collen, D.3    Holmes, W.E.4
  • 18
    • 0023871972 scopus 로고
    • Conjugation to an antifibrin monoclonal antibody enhances the fibrinolytic potency of tissue plasminogen activator in vitro
    • Runge MS, Bode C, Matsueda GR, Haber E. Conjugation to an antifibrin monoclonal antibody enhances the fibrinolytic potency of tissue plasminogen activator in vitro. Biochemistry. 1988;27: 1153-1157.
    • (1988) Biochemistry , vol.27 , pp. 1153-1157
    • Runge, M.S.1    Bode, C.2    Matsueda, G.R.3    Haber, E.4
  • 21
    • 0024582671 scopus 로고
    • Effects of thrombin inhibition on the development of acute platelet-thrombus deposition during angioplasty in pigs: Heparin versus recombinant hirudin, a specific thrombin inhibitor
    • Heras M, Chesebro JH, Penny WJ, Bailey KR, Badimon L, Fuster V. Effects of thrombin inhibition on the development of acute platelet-thrombus deposition during angioplasty in pigs: heparin versus recombinant hirudin, a specific thrombin inhibitor. Circulation. 1989;79:657-665.
    • (1989) Circulation , vol.79 , pp. 657-665
    • Heras, M.1    Chesebro, J.H.2    Penny, W.J.3    Bailey, K.R.4    Badimon, L.5    Fuster, V.6
  • 22
    • 84910715167 scopus 로고
    • Acceleration of reperfusion by combination of rt-PA and a selective thrombin inhibitor, argatroban
    • Abstract
    • Jang I, Gold HK, Leinbach RC, McNary JE, Fallon JT, Collen D. Acceleration of reperfusion by combination of rt-PA and a selective thrombin inhibitor, argatroban. Circulation. 1989;80(suppl II):II-217. Abstract.
    • (1989) Circulation , vol.80 , Issue.2 SUPPL.
    • Jang, I.1    Gold, H.K.2    Leinbach, R.C.3    McNary, J.E.4    Fallon, J.T.5    Collen, D.6
  • 23
    • 0026303904 scopus 로고
    • Thrombus resistance to lysis and reocclusion after thrombolysis: The role of platelets
    • Parise P, Agnelli G. Thrombus resistance to lysis and reocclusion after thrombolysis: the role of platelets. Blood Coagul Fibrinol. 1991;2:749-758.
    • (1991) Blood Coagul Fibrinol , vol.2 , pp. 749-758
    • Parise, P.1    Agnelli, G.2
  • 24
    • 0026514409 scopus 로고
    • Effect of thrombin inhibition on the dynamics of thrombolysis and on platelet function during thrombolytic therapy
    • Rudd MA, George D, Johnstone MT, Moore RT, Collins L, Rabbani LE, Loscalzo J. Effect of thrombin inhibition on the dynamics of thrombolysis and on platelet function during thrombolytic therapy. Circ Res. 1992;70:829-834.
    • (1992) Circ Res , vol.70 , pp. 829-834
    • Rudd, M.A.1    George, D.2    Johnstone, M.T.3    Moore, R.T.4    Collins, L.5    Rabbani, L.E.6    Loscalzo, J.7
  • 25
    • 0026020072 scopus 로고
    • Kistrin, a polypeptide platelet GPIIb/IIIa receptor antagonist, enhances and sustains coronary arterial thrombolysis with recombinant tissue-type plasminogen activator in a canine preparation
    • Yasuda T, Gold HK, Leinbach RC, Yaoita H, Fallon JT, Guerrero L, Napier MA, Bunting S, Collen D. Kistrin, a polypeptide platelet GPIIb/IIIa receptor antagonist, enhances and sustains coronary arterial thrombolysis with recombinant tissue-type plasminogen activator in a canine preparation. Circulation. 1991;83:1038-1047.
    • (1991) Circulation , vol.83 , pp. 1038-1047
    • Yasuda, T.1    Gold, H.K.2    Leinbach, R.C.3    Yaoita, H.4    Fallon, J.T.5    Guerrero, L.6    Napier, M.A.7    Bunting, S.8    Collen, D.9
  • 27
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 29
    • 0018765402 scopus 로고
    • Experimental arterial thromboembolism in baboons: Mechanisms, quantitation and pharmacologic prevention
    • Harker LA, Hanson SR. Experimental arterial thromboembolism in baboons: mechanisms, quantitation and pharmacologic prevention. J Clin Invest. 1979;64:559-560.
    • (1979) J Clin Invest. , vol.64 , pp. 559-560
    • Harker, L.A.1    Hanson, S.R.2
  • 30
    • 0024468365 scopus 로고
    • Inhibition of platelet-dependent thrombosis by low molecular weight heparin (CY222): Comparison with standard heparin
    • Cadroy Y, Harker LA, Hanson SR. Inhibition of platelet-dependent thrombosis by low molecular weight heparin (CY222): comparison with standard heparin. J Lab Clin Med. 1989;114:349-357.
    • (1989) J Lab Clin Med , vol.114 , pp. 349-357
    • Cadroy, Y.1    Harker, L.A.2    Hanson, S.R.3
  • 31
    • 0022401020 scopus 로고
    • Platelet interactions with Dacron vascular grafts: A model of acute thrombosis in baboons
    • Hanson SR, Kotze HF, Savage B, Harker LA. Platelet interactions with Dacron vascular grafts: a model of acute thrombosis in baboons. Arteriosclerosis. 1985;5:595-603.
    • (1985) Arteriosclerosis , vol.5 , pp. 595-603
    • Hanson, S.R.1    Kotze, H.F.2    Savage, B.3    Harker, L.A.4
  • 32
    • 0025318727 scopus 로고
    • Confluent durable endothelialization of endarterectomized baboon aorta by early attachment of cultured endothelial cells
    • Schneider PA, Hanson SR, Price TM, Harker LA. Confluent durable endothelialization of endarterectomized baboon aorta by early attachment of cultured endothelial cells. J Vasc Surg. 1990;11:365-372.
    • (1990) J Vasc Surg , vol.11 , pp. 365-372
    • Schneider, P.A.1    Hanson, S.R.2    Price, T.M.3    Harker, L.A.4
  • 33
    • 0001484909 scopus 로고
    • Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone
    • Hanson S, Harker L. Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone. Proc Natl Acad Sci U S A. 1988;85:3184-3188.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 3184-3188
    • Hanson, S.1    Harker, L.2
  • 35
    • 0023445541 scopus 로고
    • Antibody-enhanced thrombolysis: Targeting of tissue plasminogen activator in vivo
    • Runge MS, Bode C, Matsueda GR, Haber E. Antibody-enhanced thrombolysis: targeting of tissue plasminogen activator in vivo. Proc Natl Acad Sci U S A. 1987;84:7659-7662.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 7659-7662
    • Runge, M.S.1    Bode, C.2    Matsueda, G.R.3    Haber, E.4
  • 36
    • 0026061573 scopus 로고
    • Selective inhibition by a synthetic hirudin peptide of fibrin-dependent thrombosis in baboons
    • Cadroy Y, Maraganore JM, Hanson SR, Harker LA, Selective inhibition by a synthetic hirudin peptide of fibrin-dependent thrombosis in baboons. Proc Natl Acad Sci U S A. 1991;88:1177-1181.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 1177-1181
    • Cadroy, Y.1    Maraganore, J.M.2    Hanson, S.R.3    Harker, L.A.4
  • 37
    • 0025030398 scopus 로고
    • Inhibition of thrombus formation by activated recombinant protein C in a primate model of arterial thrombosis
    • Gruber A, Hanson SR, Kelly AB, Yan BS, Bang N, Griffin JH, Harker LA. Inhibition of thrombus formation by activated recombinant protein C in a primate model of arterial thrombosis. Circulation. 1990;82:578-585.
    • (1990) Circulation , vol.82 , pp. 578-585
    • Gruber, A.1    Hanson, S.R.2    Kelly, A.B.3    Yan, B.S.4    Bang, N.5    Griffin, J.H.6    Harker, L.A.7
  • 38
    • 0027473646 scopus 로고
    • Pharmacokinetic and thrombolytic properties of chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody fused to single-chain urokinase
    • Holvoet P, Laroche Y, Stassen JM, Lijnen HR, Van Hoef B, De Cock F, Van Houtven A, Gansemans Y, Matthyssens G, Collen D. Pharmacokinetic and thrombolytic properties of chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody fused to single-chain urokinase. Blood. 1993;81:696-703.
    • (1993) Blood , vol.81 , pp. 696-703
    • Holvoet, P.1    Laroche, Y.2    Stassen, J.M.3    Lijnen, H.R.4    Van Hoef, B.5    De Cock, F.6    Van Houtven, A.7    Gansemans, Y.8    Matthyssens, G.9    Collen, D.10
  • 39
    • 0024456136 scopus 로고
    • Correlation between template bleeding times and spontaneous bleeding during treatment of acute myocardial infarction with recombinant tissue-type plasminogen activator
    • Gimple LW, Gold HK, Leinbach RC, Coller BS, Werner W, Yasuda T, Johns JA, Ziskind AA, Finkelstein D, Collen D. Correlation between template bleeding times and spontaneous bleeding during treatment of acute myocardial infarction with recombinant tissue-type plasminogen activator. Circulation. 1989; 80:581-588.
    • (1989) Circulation , vol.80 , pp. 581-588
    • Gimple, L.W.1    Gold, H.K.2    Leinbach, R.C.3    Coller, B.S.4    Werner, W.5    Yasuda, T.6    Johns, J.A.7    Ziskind, A.A.8    Finkelstein, D.9    Collen, D.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.