Evidence that both exosites on thrombin participate in its high affinity interaction with fibrin

Journal of Biological Chemistry

Volumn 278, Issue 24, 2003, Pages 21584-21591

  Pospisil, Caroline H ^b   Stafford, Alan R ^b   Fredenburgh, James C ^b   Weitz, Jeffrey I ^a  

^a HENDERSON RESEARCH CENTRE   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; MOLECULES; NITROGEN COMPOUNDS;

THROMBIN;

PROTEINS;

EXOSITE 1; EXOSITE 2; FIBRIN; LIGAND; PROTEIN; THROMBIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

BINDING SITES; BIOCHEMISTRY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBRIN; FIBRINOGEN; HUMANS; KINETICS; LIGANDS; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THROMBIN; TIME FACTORS;

EID: 0037821812     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300545200     Document Type: Article

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