Thrombus formation in a living mouse

Pathophysiology of Haemostasis and Thrombosis

Volumn 35, Issue 1-2, 2006, Pages

  Furie, Bruce ^a,b   Furie, Barbara C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Artery; Atherothrobsis; Fibrin; Microcirculation; Murine; Platelets; Thrombus; Vessel; Wall

Indexed keywords

COLLAGEN RECEPTOR; GLYCOPROTEIN IB ALPHA; GLYCOPROTEIN VI; P SELECTIN GLYCOPROTEIN LIGAND 1; PADGEM PROTEIN; REGULATOR PROTEIN; THROMBIN RECEPTOR; VITAMIN K GROUP;

BLOOD CELL; BLOOD CLOTTING; BLOOD VESSEL INJURY; BLOOD VESSEL WALL; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CONFERENCE PAPER; CONFOCAL MICROSCOPY; CYTOLOGY; DIGITAL IMAGING; HEMOSTASIS; IN VITRO SELECTION; IN VIVO STUDY; LEUKOCYTE; MICROCIRCULATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE; THROMBOGENESIS; THROMBOSIS;

EID: 33748509099     PISSN: 14248832     EISSN: None     Source Type: Journal    
DOI: 10.1159/000093534     Document Type: Conference Paper

References (27)

1. Hsu-Lin, S., C.L. Herman, B.C. Furie, D. August, and B. Furie. 1984. A platelet membrane protein expressed during platelet activation and secretion. Studies using a monoclonal antibody specific for thrombin- activated platelets. J Biol Chem 259:9121-9126.
2. Larsen, E., A. Celi, G.E. Gilbert, B.C. Furie, J.K. Erban, R. Bonfanti, D.D. Wagner, and B. Furie. 1989. PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell 59:305-312.
3. Sako, D., X.J. Chang, K.M. Barone, G. Vachino, H.M. White, G. Shaw, G.M. Veldman, K.M. Bean, T.J. Ahem, B. Furie, and et al. 1993. Expression cloning of a functional glycoprotein ligand for P-selectin. Cell 75:1179-1186.
4. Yang, J., J. Galipeau, C.A. Kozak, B.C. Furie, and B. Furie. 1996. Mouse P-selectin glycoprotein ligand-1: molecular cloning, chromosomal localization, and expression of a functional P-selectin receptor. Blood 87:4176-4186.
5. Ley, K., D.C. Bullard, M.L. Arbones, R. Bosse, D. Vestweber, T.F. Tedder, and A.L. Beaudet. 1995. Sequential contribution of L- and P-selectin to leukocyte rolling in vivo. J Exp Med 181:669-675.
6. Falati, S., P. Gross, G. Merrill-Skoloff, B.C. Furie, and B. Furie. 2002. Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse. Nat Med 8:1175-1181.
7. Celi, A., G. Merrill-Skoloff, P. Gross, S. Falati, D.S. Sim, R. Flaumenhaft, B.C. Furie, and B. Furie. 2003. Thrombus formation: Direct real time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy. Journal of Thrombosis and Haemostasis 1:60-68.
8. Furie, B., and B.C. Furie. 2005. Thrombus formation in vivo. J Clin Invest 115:3355-3362.
9. Koyama, T., K. Nishida, S. Ohdama, M. Sawada, N. Murakami, S. Hirosawa, R. Kuriyama, K. Matsuzawa, R. Hasegawa, and N. Aoki. 1994. Determination of plasma tissue factor antigen and its clinical significance. Br J Haematol 87:343-347.
10. Fareed, J., D.D. Callas, D. Hoppensteads, and E.W. Bermes. 1995. Tissue factor antigen levels in various biological fluids. Blood Coagulation Fibrinolysis 6 [Suppl 1]:S32-36.
11. Zumbach, M., M. Hofmann, V. Borcea, T. Luther, M. Kotzsch, M. Muller, O. Hergesell, K. Andrassy, E. Ritz, R. Ziegler, P. Wahl, and P.P. Nawroth. 1997. Tissue factor antigen is elevated in patients with microvascular complications of diabetes mellitus. Experimental Clinical Endocrinology Diabetes 105:206-212.
12. Giesen, P.L., U. Rauch, B. Bohrmann, D. Kling, M. Roque, J.T. Fallon, J.J. Badimon, J. Himber, M.A. Riederer, and Y. Nemerson. 1999. Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci U S A 96:2311-2315.
13. Parry, G.C., J.H. Erlich, P. Carmeliet, T. Luther, and N. Mackman. 1998. Low levels of tissue factor are compatible with development and hemostasis in mice. J Clin Invest 101:560-569.
14. Toomey, J.R., K.E. Kratzer, N.M. Lasky, J.J. Stanton, and G.J. Broze, Jr. 1996. Targeted disruption of the murine tissue factor gene results in embryonic lethality. Blood 88:1583-1587.
15. Bugge, T.H., Q. Xiao, K.W. Kombrinck, M.J. Flick, K. Holmback, M.J. Danton, M.C. Colbert, D.P. Witte, K. Fujikawa, E.W. Davie, and J.L. Degen. 1996. Fatal embryonic bleeding events in mice lacking tissue factor, the cell- associated initiator of blood coagulation. Proc Natl Acad Sci U S A 93:6258-6263.
16. Carmeliet, P., V. Ferreira, G. Breier, S. Pollefeyt, L. Kieckens, M. Gertsenstein, M. Fahrig, A. Vandenhoeck, K. Harpal, C. Eberhardt, C. Declercq, J. Pawling, L. Moons, D. Collen, W. Risau, and A. Nagy. 1996. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380:435-439.
17. Chou, J., N. Mackman, G. Merrill-Skoloff, B. Pedersen, B.C. Furie, and B. Furie. 2004. Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation. Blood 104:3190-3197.
18. Falati, S., Q. Liu, P. Gross, G. Merrill-Skoloff, J. Chou, E. Vandendries, A. Celi, K. Croce, B.C. Furie, and B. Furie. 2003. Accumulation of Tissue Factor into Developing Thrombi In Vivo Is Dependent upon Microparticle P-Selectin Glycoprotein Ligand 1 and Platelet P-Selectin. J Exp Med 197:1585-1598.
19. Palabrica, T., R. Lobb, B.C. Furie, M. Aronovitz, C. Benjamin, Y.M. Hsu, S.A. Sajer, and B. Furie. 1992. Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets. Nature 359:848-851.
20. Gross, P.L., B.C. Furie, G. Merrill-Skoloff, J. Chou, and B. Furie. 2005. Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development. J Leukoc Biol 78:1318-1326.
21. Nieswandt, B., W. Bergmeier, V. Schulte, K. Rackebrandt, J.E. Gessner, and H. Zirngibl. 2000. Expression and function of the mouse collagen receptor glycoprotein VI is strictly dependent on its association with the FcRgamma chain. J Biol Chem 275:23998-24002.
22. Dubois, C., L. Panicot-Dubois, G. Merrill-Skoloff, B. Furie, and B.C. Furie. 2006. Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo. Blood.
23. Vandendries, E., J.R. Hamilton, S.R. Coughlin, B.C. Furie, and B. Furie. 2004. Protease-Activator Receptor 4 Is Required for Maximal Thrombus Growth, but Not for Fibrin Generation in Thrombi after Laser Injury. Blood 104:624.
24. Dubois, C., L. Panicot-Dubois, B.C. Furie, and B. Furie. 2004. Direct Real Time Visualization of Platelet Calclium Signaling In Vivo: Role of Platelet Activation and Thrombus Formation in a Living Mouse. Blood 104:325.
25. Arias-Salgado, E.G., H. Fawaz, C. Dubois, B.C. Furie, B. Furie, B.G. Neel, and S.J. Shattil. 2005. Protein tyrosine phosphatase PTP-1B is an essential positive regulator of platelet thrombus formation and outside-in IIb 3 signaling. J. Cell Biol. In press.
26. Berman, C.L., E. Yeo, J.D. Wencel-Drake, B.C. Furie, M.H. Ginsberg, and B. Furie. 1986. A platelet alpha granule membrane protein that is incorporated into the plasma membrane during activation. Characterization and subcellular localization of PADGEM protein. Journal of Clinical Investigation 78:130-137.
27. Sim, D.S., G. Merrill-Skoloff, B.C. Furie, B. Furie, and R. Flaumenhaft. 2004. Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels. Blood 103:2127-2134.