Discovery of osmosensitive transcriptional regulation of human cytochrome P450 3As by the tonicity-responsive enhancer binding protein (nuclear factor of activated T cells 5)

Molecular Pharmacology

Volumn 72, Issue 4, 2007, Pages 826-837

  Kosuge, Kazuhiro ^a   Chuang, Andrew I ^a   Uematsu, Satoko ^a   Kah, Poh Tan ^a   Ohashi, Kyoichi ^d   Ko, Ben C B ^b,c   Ito, Shinya ^a,e  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d OITA UNIVERSITY   (Japan)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; CYTOCHROME P450 3A7; HYPERTONIC SOLUTION; LUCIFERASE; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT5; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN HEPG2; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG ELIMINATION; DRUG EXCRETION; DRUG METABOLISM; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTESTINE CELL; INTRON; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; OSMOLALITY; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; STATISTICAL ANALYSIS; TRANSACTIVATION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

CELL LINE; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; NFATC TRANSCRIPTION FACTORS; OSMOLAR CONCENTRATION; TRANSCRIPTION, GENETIC;

EID: 34748816192     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.034504     Document Type: Article

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