Dietary salt increases first-pass elimination of oral quinidine

Clinical Pharmacology and Therapeutics

Volumn 61, Issue 3, 1997, Pages 292-300

  Darbar, Dawood ^a   Dell'Orto, Simonetta ^a   Mörike, Klaus ^a   Wilkinson, Grant R ^a   Roden, Dan M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; QUINIDINE; SODIUM CHLORIDE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIET; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; HOMEOSTASIS; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ADULT; ANTI-ARRHYTHMIA AGENTS; AREA UNDER CURVE; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; INTESTINES; MALE; OXIDOREDUCTASES, N-DEMETHYLATING; QUINIDINE; REFERENCE VALUES; SODIUM, DIETARY; TIME FACTORS;

EID: 0030973783     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9236(97)90161-2     Document Type: Article

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