메뉴 건너뛰기




Volumn 313, Issue 17, 2007, Pages 3718-3728

Promoter-independent regulation of vimentin expression in mammary epithelial cells by val12 ras and TGFβ

Author keywords

EMT; Metastasis; Suppression; TGF ; Vimentin

Indexed keywords

AZACITIDINE; TRANSFORMING GROWTH FACTOR BETA; VIMENTIN;

EID: 34648847327     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.07.026     Document Type: Article
Times cited : (17)

References (60)
  • 1
    • 0036830524 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: a mesodermal cell strategy for evolutive innovation in Metazoans
    • Perez-Pomares J.M., and Munoz-Chapuli R. Epithelial-mesenchymal transitions: a mesodermal cell strategy for evolutive innovation in Metazoans. Anat. Rec. 268 (2002) 343-351
    • (2002) Anat. Rec. , vol.268 , pp. 343-351
    • Perez-Pomares, J.M.1    Munoz-Chapuli, R.2
  • 2
    • 3342934231 scopus 로고    scopus 로고
    • Transforming growth factor beta (TGFbeta) signalling in palatal growth, apoptosis and epithelial mesenchymal transformation (EMT)
    • Nawshad A., LaGamba D., and Hay E.D. Transforming growth factor beta (TGFbeta) signalling in palatal growth, apoptosis and epithelial mesenchymal transformation (EMT). Arch. Oral Biol. 49 (2004) 675-689
    • (2004) Arch. Oral Biol. , vol.49 , pp. 675-689
    • Nawshad, A.1    LaGamba, D.2    Hay, E.D.3
  • 4
    • 0034798707 scopus 로고    scopus 로고
    • Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition
    • Savagner P. Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition. BioEssays 23 (2001) 912-923
    • (2001) BioEssays , vol.23 , pp. 912-923
    • Savagner, P.1
  • 5
    • 0037699018 scopus 로고    scopus 로고
    • Overexpression of vimentin: role in the invasive phenotype in an androgen-independent model of prostate cancer
    • Singh S., Sadacharan S., Su S., Belldegrun A., Persad S., and Singh G. Overexpression of vimentin: role in the invasive phenotype in an androgen-independent model of prostate cancer. Cancer Res. 63 (2003) 2306-2311
    • (2003) Cancer Res. , vol.63 , pp. 2306-2311
    • Singh, S.1    Sadacharan, S.2    Su, S.3    Belldegrun, A.4    Persad, S.5    Singh, G.6
  • 8
    • 0035147248 scopus 로고    scopus 로고
    • Co-expression of tenascin-C and vimentin in human breast cancer cells indicates phenotypic transdifferentiation during tumour progression: correlation with histopathological parameters, hormone receptors, and oncoproteins
    • Dandachi N., Hauser-Kronberger C., More E., Wiesener B., Hacker G.W., Dietze O., and Wirl G. Co-expression of tenascin-C and vimentin in human breast cancer cells indicates phenotypic transdifferentiation during tumour progression: correlation with histopathological parameters, hormone receptors, and oncoproteins. J. Pathol. 193 (2001) 181-189
    • (2001) J. Pathol. , vol.193 , pp. 181-189
    • Dandachi, N.1    Hauser-Kronberger, C.2    More, E.3    Wiesener, B.4    Hacker, G.W.5    Dietze, O.6    Wirl, G.7
  • 9
    • 0035185853 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism
    • Bhowmick N.A., Ghiassi M., Bakin A., Aakre M., Lundquist C.A., Engel M.E., Arteaga C.L., and Moses H.L. Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol. Biol. Cell 12 (2001) 27-36
    • (2001) Mol. Biol. Cell , vol.12 , pp. 27-36
    • Bhowmick, N.A.1    Ghiassi, M.2    Bakin, A.3    Aakre, M.4    Lundquist, C.A.5    Engel, M.E.6    Arteaga, C.L.7    Moses, H.L.8
  • 10
    • 0029662049 scopus 로고    scopus 로고
    • TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
    • Oft M., Peli J., Rudaz C., Schwarz H., Beug H., and Reichmann E. TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev. 10 (1996) 2462-2477
    • (1996) Genes Dev. , vol.10 , pp. 2462-2477
    • Oft, M.1    Peli, J.2    Rudaz, C.3    Schwarz, H.4    Beug, H.5    Reichmann, E.6
  • 11
    • 0036304111 scopus 로고    scopus 로고
    • Metastasis is driven by sequential elevation of H-ras and Smad2 levels
    • Oft M., Akhurst R.J., and Balmain A. Metastasis is driven by sequential elevation of H-ras and Smad2 levels. Nat. Cell Biol. 4 (2002) 487-494
    • (2002) Nat. Cell Biol. , vol.4 , pp. 487-494
    • Oft, M.1    Akhurst, R.J.2    Balmain, A.3
  • 12
    • 0036084359 scopus 로고    scopus 로고
    • TGF-beta antagonists: why suppress a tumor suppressor?
    • Akhurst R.J. TGF-beta antagonists: why suppress a tumor suppressor?. J. Clin. Invest. 109 (2002) 1533-1536
    • (2002) J. Clin. Invest. , vol.109 , pp. 1533-1536
    • Akhurst, R.J.1
  • 13
    • 0033377548 scopus 로고    scopus 로고
    • TGF-beta and cancer
    • Reiss M. TGF-beta and cancer. Microbes Infect. 1 (1999) 1327-1347
    • (1999) Microbes Infect. , vol.1 , pp. 1327-1347
    • Reiss, M.1
  • 14
    • 33845524970 scopus 로고    scopus 로고
    • Transforming growth factor-beta in cancer and metastasis
    • Jakowlew S.B. Transforming growth factor-beta in cancer and metastasis. Cancer Metastasis Rev. 25 (2006) 435-457
    • (2006) Cancer Metastasis Rev. , vol.25 , pp. 435-457
    • Jakowlew, S.B.1
  • 15
    • 24644487312 scopus 로고    scopus 로고
    • TGF-beta and epithelial-to-mesenchymal transitions
    • Zavadil J., and Bottinger E.P. TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 24 (2005) 5764-5774
    • (2005) Oncogene , vol.24 , pp. 5764-5774
    • Zavadil, J.1    Bottinger, E.P.2
  • 16
    • 0043172396 scopus 로고    scopus 로고
    • Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
    • Grunert S., Jechlinger M., and Beug H. Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat. Rev., Mol. Cell Biol. 4 (2003) 657-665
    • (2003) Nat. Rev., Mol. Cell Biol. , vol.4 , pp. 657-665
    • Grunert, S.1    Jechlinger, M.2    Beug, H.3
  • 17
    • 0024571416 scopus 로고
    • AP-1/jun binding sites mediate serum inducibility of the human vimentin promoter
    • Rittling S.R., Coutinho L., Amram T., and Kolbe M. AP-1/jun binding sites mediate serum inducibility of the human vimentin promoter. Nucleic Acids Res. 17 (1989) 1619-1633
    • (1989) Nucleic Acids Res. , vol.17 , pp. 1619-1633
    • Rittling, S.R.1    Coutinho, L.2    Amram, T.3    Kolbe, M.4
  • 18
    • 0023449347 scopus 로고
    • Functional analysis and growth factor regulation of the human vimentin promoter
    • Rittling S.R., and Baserga R. Functional analysis and growth factor regulation of the human vimentin promoter. Mol. Cell. Biol. 7 (1987) 3908-3915
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3908-3915
    • Rittling, S.R.1    Baserga, R.2
  • 19
    • 0027955576 scopus 로고
    • Multiple silencer elements are involved in regulating the chicken vimentin gene
    • Garzon R.J., and Zehner Z.E. Multiple silencer elements are involved in regulating the chicken vimentin gene. Mol. Cell. Biol. 14 (1994) 934-943
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 934-943
    • Garzon, R.J.1    Zehner, Z.E.2
  • 20
    • 0027498310 scopus 로고
    • Identification of a negative element in the human vimentin promoter: modulation by the human T-cell leukemia virus type I Tax protein
    • Salvetti A., Lilienbaum A., Li Z., Paulin D., and Gazzolo L. Identification of a negative element in the human vimentin promoter: modulation by the human T-cell leukemia virus type I Tax protein. Mol. Cell. Biol. 13 (1993) 89-97
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 89-97
    • Salvetti, A.1    Lilienbaum, A.2    Li, Z.3    Paulin, D.4    Gazzolo, L.5
  • 22
    • 0037251307 scopus 로고    scopus 로고
    • Novel murine mammary epithelial cell lines that form osteolytic bone metastases: effect of strain background on tumor homing
    • Chen Y., and Rittling S.R. Novel murine mammary epithelial cell lines that form osteolytic bone metastases: effect of strain background on tumor homing. Clin. Exp. Metastasis 20 (2003) 111-120
    • (2003) Clin. Exp. Metastasis , vol.20 , pp. 111-120
    • Chen, Y.1    Rittling, S.R.2
  • 25
    • 0030840409 scopus 로고    scopus 로고
    • Osteopontin expression in mammary gland development and tumorigenesis
    • Rittling S.R., and Novick K.E. Osteopontin expression in mammary gland development and tumorigenesis. Cell Growth Differ. 8 (1997) 1061-1069
    • (1997) Cell Growth Differ. , vol.8 , pp. 1061-1069
    • Rittling, S.R.1    Novick, K.E.2
  • 26
    • 0026781976 scopus 로고
    • Loss of epithelial markers and acquisition of vimentin expression in adriamycin- and vinblastine-resistant human breast cancer cell lines
    • Sommers C.L., Heckford S.E., Skerker J.M., Worland P., Torri J.A., Thompson E.W., Byers S.W., and Gelmann E.P. Loss of epithelial markers and acquisition of vimentin expression in adriamycin- and vinblastine-resistant human breast cancer cell lines. Cancer Res. 52 (1992) 5190-5197
    • (1992) Cancer Res. , vol.52 , pp. 5190-5197
    • Sommers, C.L.1    Heckford, S.E.2    Skerker, J.M.3    Worland, P.4    Torri, J.A.5    Thompson, E.W.6    Byers, S.W.7    Gelmann, E.P.8
  • 27
    • 0032544465 scopus 로고    scopus 로고
    • Detection of mouse osteopontin by Western blotting
    • Rittling S.R., and Feng F. Detection of mouse osteopontin by Western blotting. Biochem. Biophys. Res. Commun. 250 (1998) 287-292
    • (1998) Biochem. Biophys. Res. Commun. , vol.250 , pp. 287-292
    • Rittling, S.R.1    Feng, F.2
  • 28
    • 0034568227 scopus 로고    scopus 로고
    • Smad protein expression and activation in transforming growth factor-beta refractory human squamous cell carcinoma cells
    • Yan W., Vellucci V.F., and Reiss M. Smad protein expression and activation in transforming growth factor-beta refractory human squamous cell carcinoma cells. Oncol. Res. 12 (2000) 157-167
    • (2000) Oncol. Res. , vol.12 , pp. 157-167
    • Yan, W.1    Vellucci, V.F.2    Reiss, M.3
  • 29
    • 33144458447 scopus 로고    scopus 로고
    • Override of the osteoclast defect in osteopontin-deficient mice by metastatic tumor growth in the bone
    • Natasha T., Kuhn M., Kelly O., and Rittling S.R. Override of the osteoclast defect in osteopontin-deficient mice by metastatic tumor growth in the bone. Am. J. Pathol. 168 (2006) 551-561
    • (2006) Am. J. Pathol. , vol.168 , pp. 551-561
    • Natasha, T.1    Kuhn, M.2    Kelly, O.3    Rittling, S.R.4
  • 30
    • 33747507303 scopus 로고    scopus 로고
    • A mouse model of breast cancer metastasis to the choroid of the eye
    • Kuhn M., Shah S., Natasha T., and Rittling S.R. A mouse model of breast cancer metastasis to the choroid of the eye. Clin. Exp. Metastasis 22 (2005) 685-690
    • (2005) Clin. Exp. Metastasis , vol.22 , pp. 685-690
    • Kuhn, M.1    Shah, S.2    Natasha, T.3    Rittling, S.R.4
  • 31
    • 0032144865 scopus 로고    scopus 로고
    • The mRNA expression of cytokines and their receptors in cultured iris pigment epithelial cells: a comparison with retinal pigment epithelial cells
    • Kociok N., Heppekausen H., Schraermeyer U., Esser P., Thumann G., Grisanti S., and Heimann K. The mRNA expression of cytokines and their receptors in cultured iris pigment epithelial cells: a comparison with retinal pigment epithelial cells. Exp. Eye Res. 67 (1998) 237-250
    • (1998) Exp. Eye Res. , vol.67 , pp. 237-250
    • Kociok, N.1    Heppekausen, H.2    Schraermeyer, U.3    Esser, P.4    Thumann, G.5    Grisanti, S.6    Heimann, K.7
  • 32
    • 0027176457 scopus 로고
    • Functional analysis of chicken vimentin distal promoter regions in cultured lens cells
    • Sax C.M., Stover D.M., Ilagan J.G., Zehner Z.E., and Piatigorsky J. Functional analysis of chicken vimentin distal promoter regions in cultured lens cells. Gene 130 (1993) 277-281
    • (1993) Gene , vol.130 , pp. 277-281
    • Sax, C.M.1    Stover, D.M.2    Ilagan, J.G.3    Zehner, Z.E.4    Piatigorsky, J.5
  • 33
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev., Genet. 3 (2002) 415-428
    • (2002) Nat. Rev., Genet. , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 34
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction?
    • Baylin S.B., and Ohm J.E. Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction?. Nat. Rev., Cancer 6 (2006) 107-116
    • (2006) Nat. Rev., Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 35
    • 33749013323 scopus 로고    scopus 로고
    • Silencing of the metastasis suppressor RECK by RAS oncogene is mediated by DNA methyltransferase 3b-induced promoter methylation
    • Chang H.C., Cho C.Y., and Hung W.C. Silencing of the metastasis suppressor RECK by RAS oncogene is mediated by DNA methyltransferase 3b-induced promoter methylation. Cancer Res. 66 (2006) 8413-8420
    • (2006) Cancer Res. , vol.66 , pp. 8413-8420
    • Chang, H.C.1    Cho, C.Y.2    Hung, W.C.3
  • 37
    • 16244364806 scopus 로고    scopus 로고
    • Methylation and inhibition of expression of uPA by the RAS oncogene: divergence of growth control and invasion in breast cancer cells
    • Pakneshan P., Szyf M., and Rabbani S.A. Methylation and inhibition of expression of uPA by the RAS oncogene: divergence of growth control and invasion in breast cancer cells. Carcinogenesis 26 (2005) 557-564
    • (2005) Carcinogenesis , vol.26 , pp. 557-564
    • Pakneshan, P.1    Szyf, M.2    Rabbani, S.A.3
  • 38
    • 16344378397 scopus 로고    scopus 로고
    • TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
    • Valcourt U., Kowanetz M., Niimi H., Heldin C.H., and Moustakas A. TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. Mol. Biol. Cell 16 (2005) 1987-2002
    • (2005) Mol. Biol. Cell , vol.16 , pp. 1987-2002
    • Valcourt, U.1    Kowanetz, M.2    Niimi, H.3    Heldin, C.H.4    Moustakas, A.5
  • 41
    • 0037148532 scopus 로고    scopus 로고
    • Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways
    • Janda E., Lehmann K., Killisch I., Jechlinger M., Herzig M., Downward J., Beug H., and Grunert S. Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J. Cell Biol. 156 (2002) 299-313
    • (2002) J. Cell Biol. , vol.156 , pp. 299-313
    • Janda, E.1    Lehmann, K.2    Killisch, I.3    Jechlinger, M.4    Herzig, M.5    Downward, J.6    Beug, H.7    Grunert, S.8
  • 42
  • 43
    • 0033119153 scopus 로고    scopus 로고
    • An antisilencer element is involved in the transcriptional regulation of the human vimentin gene
    • Izmailova E.S., and Zehner Z.E. An antisilencer element is involved in the transcriptional regulation of the human vimentin gene. Gene 230 (1999) 111-120
    • (1999) Gene , vol.230 , pp. 111-120
    • Izmailova, E.S.1    Zehner, Z.E.2
  • 44
    • 0034787967 scopus 로고    scopus 로고
    • MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits
    • Tester A.M., Ruangpanit N., Anderson R.L., and Thompson E.W. MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits. Clin. Exp. Metastasis 18 (2000) 553-560
    • (2000) Clin. Exp. Metastasis , vol.18 , pp. 553-560
    • Tester, A.M.1    Ruangpanit, N.2    Anderson, R.L.3    Thompson, E.W.4
  • 45
    • 0038756636 scopus 로고    scopus 로고
    • Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions
    • Peinado H., Quintanilla M., and Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J. Biol. Chem. 278 (2003) 21113-21123
    • (2003) J. Biol. Chem. , vol.278 , pp. 21113-21123
    • Peinado, H.1    Quintanilla, M.2    Cano, A.3
  • 47
    • 0028022784 scopus 로고
    • Immortalization of multiple cell types from transgenic mice using a transgene containing the vimentin promoter and a conditional oncogene
    • Vicart P., Schwartz B., Vandewalle A., Bens M., Delouis C., Panthier J.J., Pournin S., Babinet C., and Paulin D. Immortalization of multiple cell types from transgenic mice using a transgene containing the vimentin promoter and a conditional oncogene. Exp. Cell Res. 214 (1994) 35-45
    • (1994) Exp. Cell Res. , vol.214 , pp. 35-45
    • Vicart, P.1    Schwartz, B.2    Vandewalle, A.3    Bens, M.4    Delouis, C.5    Panthier, J.J.6    Pournin, S.7    Babinet, C.8    Paulin, D.9
  • 49
    • 0042972556 scopus 로고    scopus 로고
    • Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
    • Watnick R.S., Cheng Y.N., Rangarajan A., Ince T.A., and Weinberg R.A. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell 3 (2003) 219-231
    • (2003) Cancer Cell , vol.3 , pp. 219-231
    • Watnick, R.S.1    Cheng, Y.N.2    Rangarajan, A.3    Ince, T.A.4    Weinberg, R.A.5
  • 50
    • 2342457639 scopus 로고    scopus 로고
    • Transcription repression in oncogenic transformation: common targets of epigenetic repression in cells transformed by Fos, Ras or Dnmt1
    • Ordway J.M., Williams K., and Curran T. Transcription repression in oncogenic transformation: common targets of epigenetic repression in cells transformed by Fos, Ras or Dnmt1. Oncogene 23 (2004) 3737-3748
    • (2004) Oncogene , vol.23 , pp. 3737-3748
    • Ordway, J.M.1    Williams, K.2    Curran, T.3
  • 51
    • 0025371673 scopus 로고
    • A negative element involved in vimentin gene expression
    • Farrell F.X., Sax C.M., and Zehner Z.E. A negative element involved in vimentin gene expression. Mol. Cell. Biol. 10 (1990) 2349-2358
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 2349-2358
    • Farrell, F.X.1    Sax, C.M.2    Zehner, Z.E.3
  • 52
    • 0035936918 scopus 로고    scopus 로고
    • Involvement of histone H4 gene transcription factor 1 in downregulation of vimentin gene expression during skeletal muscle differentiation
    • Kryszke M.H., Moura-Neto V., Lilienbaum A., Paulin D., and Auclair C. Involvement of histone H4 gene transcription factor 1 in downregulation of vimentin gene expression during skeletal muscle differentiation. FEBS Lett. 491 (2001) 30-34
    • (2001) FEBS Lett. , vol.491 , pp. 30-34
    • Kryszke, M.H.1    Moura-Neto, V.2    Lilienbaum, A.3    Paulin, D.4    Auclair, C.5
  • 53
    • 33847039608 scopus 로고    scopus 로고
    • TGFbeta1 regulation of vimentin gene expression during differentiation of the C2C12 skeletal myogenic cell line requires Smads, AP-1 and Sp1 family members
    • Wu Y., Zhang X., Salmon M., Lin X., and Zehner Z.E. TGFbeta1 regulation of vimentin gene expression during differentiation of the C2C12 skeletal myogenic cell line requires Smads, AP-1 and Sp1 family members. Biochim. Biophys. Acta 1773 (2007) 427-439
    • (2007) Biochim. Biophys. Acta , vol.1773 , pp. 427-439
    • Wu, Y.1    Zhang, X.2    Salmon, M.3    Lin, X.4    Zehner, Z.E.5
  • 54
    • 22244432840 scopus 로고    scopus 로고
    • The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program
    • De Craene B., Gilbert B., Stove C., Bruyneel E., van Roy F., and Berx G. The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program. Cancer Res. 65 (2005) 6237-6244
    • (2005) Cancer Res. , vol.65 , pp. 6237-6244
    • De Craene, B.1    Gilbert, B.2    Stove, C.3    Bruyneel, E.4    van Roy, F.5    Berx, G.6
  • 55
    • 33646596637 scopus 로고    scopus 로고
    • Cooperation between snail and LEF-1 transcription factors is essential for TGF-beta1-induced epithelial-mesenchymal transition
    • Medici D., Hay E.D., and Goodenough D.A. Cooperation between snail and LEF-1 transcription factors is essential for TGF-beta1-induced epithelial-mesenchymal transition. Mol. Biol. Cell 17 (2006) 1871-1879
    • (2006) Mol. Biol. Cell , vol.17 , pp. 1871-1879
    • Medici, D.1    Hay, E.D.2    Goodenough, D.A.3
  • 56
    • 33747625686 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail
    • Grotegut S., von Schweinitz D., Christofori G., and Lehembre F. Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail. EMBO J. 25 (2006) 3534-3545
    • (2006) EMBO J. , vol.25 , pp. 3534-3545
    • Grotegut, S.1    von Schweinitz, D.2    Christofori, G.3    Lehembre, F.4
  • 59
    • 33645733588 scopus 로고    scopus 로고
    • N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1
    • Alexander N.R., Tran N.L., Rekapally H., Summers C.E., Glackin C., and Heimark R.L. N-cadherin gene expression in prostate carcinoma is modulated by integrin-dependent nuclear translocation of Twist1. Cancer Res. 66 (2006) 3365-3369
    • (2006) Cancer Res. , vol.66 , pp. 3365-3369
    • Alexander, N.R.1    Tran, N.L.2    Rekapally, H.3    Summers, C.E.4    Glackin, C.5    Heimark, R.L.6
  • 60
    • 0038282427 scopus 로고    scopus 로고
    • Analysis of regulatory elements of E-cadherin with reporter gene constructs in transgenic mouse embryos
    • Stemmler M.P., Hecht A., Kinzel B., and Kemler R. Analysis of regulatory elements of E-cadherin with reporter gene constructs in transgenic mouse embryos. Dev. Dyn. 227 (2003) 238-245
    • (2003) Dev. Dyn. , vol.227 , pp. 238-245
    • Stemmler, M.P.1    Hecht, A.2    Kinzel, B.3    Kemler, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.