Oncogenic HRAS suppresses clusterin expression through promoter hypermethylation

Oncogene

Volumn 25, Issue 35, 2006, Pages 4890-4903

  Lund, P ^a   Weisshaupt K ^a   Mikeska, T ^b   Jammas, D ^b   Chen, X ^a   Kuban, R J ^a   Ungethum U ^a   Krapfenbauer, U ^a   Herzel, H P ^c   Schafer R ^a   Walter, J ^b   Sers, C ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Clusterin; CpG methylation; Gene expression; HRAS(G12V); MEK ERK signalling; Mmp2

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 5 AZA 2' DEOXYCYTIDINE; C REACTIVE PROTEIN; CLUSTERIN; GELATINASE A; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; SYNDECAN 4; THROMBOSPONDIN 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; CPG ISLAND; DNA MICROARRAY; FIBROBLAST; GENE EXPRESSION; GENE IDENTIFICATION; GENE SEQUENCE; GENE SILENCING; METHYLATION; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; ONCOGENE H RAS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; AZACITIDINE; CELL LINE, TRANSFORMED; CLUSTERIN; DNA METHYLATION; GENES, RAS; GENES, SUPPRESSOR; HYDROXAMIC ACIDS; PROMOTER REGIONS (GENETICS); RATS; SIGNAL TRANSDUCTION;

EID: 33746910577     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209502     Document Type: Article

References (68)

1. Avner P, Heard E. (2001). Nat Rev Genet 2: 59-67.
2. Baker KM, Wei G, Schaffner AE, Ostrowski MC. (2003). J Biol Chem 278: 17876-17884.
3. Bakin AV, Curran T. (1999). Science 283: 387-390.
4. Behrens P, Jeske W, Wernert N, Wellmann A. (2001). Pathobiology 69: 19-23.
5. Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K et al. (2000). Nat Cell Biol 2: 737-744.
6. Bos JL. (1989). Cancer Res 49: 4682-4689.
7. Brazma A, Hingamp P, Quackenbush J, Sherlock G, Spellman P, Stoeckert C et al. (2001). Nat Genet 29: 365-371.
8. Brem R, Certa U, Neeb M, Nair AP, Moroni C. (2001). Oncogene 20: 2854-2858.
9. Brenner C, Deplus R, Didelot C, Loriot A, Vire E, De Smet C et al. (2005). EMBO J 24: 336-346.
10. Campbell SL, Khosravi-Far R, Rossman KL, Clark GJ, Der CJ. (1998). Oncogene 17: 1395-1413.
11. Cappabianca L, Farina AR, Tacconelli A, Mantovani R, Gulino A, Mackay AR. (2003). Exp Cell Res 286: 209-218.
12. Chen T, Turner J, McCarthy S, Scaltriti M, Bettuzzi S, Yeatman TJ. (2004). Cancer Res 64: 7412-7419.
13. Criswell TL, Beman M, Araki S, Leskov K, Cataldo E, Mayo LD et al. (2005). J Biol Chem 280: 14212-14221.
14. Deryugina EI, Luo GX, Reisfeld RA, Bourdon MA, Strongin A. (1997). Anticancer Res 17: 3201-3210.
15. Deryugina EI, Ratnikov B, Monosov E, Postnova TI, DiScipio R, Smith JW et al. (2001). Exp Cell Res 263: 209-223.
16. Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M et al. (2002). Science 295: 1079-1082.
17. Downward J. (1998). Curr Op Genet Dev 8: 49-54.
18. Esteller M. (2002). Oncogene 21: 5427-5440.
19. Esteller M. (2003). Lancet Oncol 4: 351-358.
20. Esteller M, Corn PG, Baylin SB, Herman JG. (2001). Cancer Res 61: 3225-3229.
21. Fensterer H, Giehl K, Buchholz M, Ellenrieder V, Buck A, Kestler HA et al. (2004). Genes Chromosomes Cancer 39: 224-235.
22. Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T. (2000). Nat Genet 24: 88-91.
23. Fuks F, Hurd PJ, Deplus R, Kouzarides T. (2003a). Nucleic Acids Res 31: 2305-2312.
24. Fuks F, Hurd PJ, Wolf D, Nan X, Bird AP, Kouzarides T. (2003b). J Biol Chem 278: 4035-4040.
25. Gadal F, Bozic C, Pillot-Brochet C, Malinge S, Wagner S, Le Cam A et al. (2003). Nucleic Acids Res 31: 5789-5804.
26. Griegel S, Traub O, Willecke K, Schäfer R. (1986). Int J Cancer 38: 697-705.
27. Hsieh CL. (1994). Mol Cell Biol 14: 5487-5494.
28. Issa JP, Vertino PM, Wu J, Sazawal S, Celano P, Nelkin BD et al. (1993). J Natl Cancer Inst 85: 1235-1240.
29. Itoh T, Tanioka M, Yoshida H, Yoshioka T, Nishimoto H, Itohara S. (1998). Cancer Res 58: 1048-1051.
30. Ivanova T, Vinokurova S, Petrenko A, Eshilev E, Solovyova N, Kisseljov F et al. (2004). Int J Cancer 108: 882-886.
31. Jones SE, Jomary C. (2002). Int J Biochem Cell Biol 34: 427-431.
32. Kautiainen TL, Jones PA. (1986). J Biol Chem 261: 1594-1598.
33. Klock G, Storch S, Rickert J, Gutacker C, Koch-Brandt C. (1998). J Cell Physiol 177: 593-605.
34. Kyprianou N, English HF, Davidson NE, Isaacs JT. (1991). Cancer Res 51: 162-166.
35. Lachner M, Jenuwein T. (2002). Curr Opin Cell Biol 14: 286-298.
36. Laduron S, Deplus R, Zhou S, Kholmanskikh O, Godelaine D, De Smet C et al. (2004). Nucleic Acids Res 32: 4340-4350.
37. Leskov KS, Klokov DY, Li J, Kinsella TJ, Boothman DA. (2003). J Biol Chem 278: 11590-11600.
38. Li LC, Dahiya R. (2002). Bioinformatics 18: 1427-1431.
39. Li Q, Ahuja N, Burger PC, Issa JP. (1999). Oncogene 18: 3284-3289.
40. Liu HS, Scrable H, Villaret DB, Lieberman MA, Stambrook PJ. (1992). Cancer Res 52: 983-989.
41. Lopes S, Lewis A, Hajkova P, Dean W, Oswald J, Forne T et al. (2003). Hum Mol Genet 12: 295-305.
42. Lymar ES, Clark AM, Reeves R, Griswold MD. (2000). Biol Reprod 63: 1341-1351.
43. Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K et al. (1994). Science 265: 966-970.
44. Olek A, Oswald J, Walter J. (1996). Nucleic Acids Res 24: 5064-5066.
45. Ordway JM, Williams K, Curran T. (2004). Oncogene 23: 3737-3748.
46. Pucci S, Bonanno E, Pichiorri F, Angeloni C, Spagnoli LG. (2004). Oncogene 23: 2298-2304.
47. Raudies O, Kuban RJ, Hamacher F, Klein-Hitpass L, Tchernitsa OI, Sers C et al. (2005). Adv Enzyme Regul 45: 63-84.
48. Reik W, Walter J. (2001). Nat Rev Genet 2: 21-32.
49. Reik W, Dean W, Walter J. (2001). Science 293: 1089-1093.
50. Rosemblit N, Chen CL. (1994). J Mol Endocrinol 13: 69-76.
51. Rouleau J, Macleod AR, Szyf M. (1995). J Biol Chem 270: 1595-1601.
52. Scaltriti M, Brausi M, Amorosi A, Caporali A, D'Arca D, Astancolle S et al. (2004a). Int J Cancer 108: 23-30.
53. Scaltriti M, Santamaria A, Paciucci R, Bettuzzi S. (2004b). Cancer Res 64: 6174-6182.
54. Schäfer R, Iyer J, Iten E, Nirkko AC. (1988). Proc Natl Acad Soc USA 85: 1590-1594.
55. Schneider-Stock R, Dias-Assef M, Rohrbeck A, Foltzer-Jourdainne C, Boltze C, Hartig R et al. (2005). J Pharmacol Exp Ther 312: 525-536.
56. Schwarte-Waldhoff I, Martin W, Willecke K, Schäfer R. (1994). Oncogene 9: 899-909.
57. Sers C, Tchernitsa OI, Zuber J, Diatchenko L, Zhumabayeva B, Desai S et al. (2002). Adv Enzyme Regul 42: 63-82.
58. Takai D, Jones PA. (2002). Proc Natl Acad Sci USA 99: 3740-3745.
59. Taraboletti G, Morbidelli L, Donnini S, Parenti A, Granger HJ, Giavazzi R et al. (2000). FASEB J 14: 1674-1676.
60. Tchernitsa OI, Sers C, Zuber J, Hinzmann B, Grips M, Schwendel A et al. (2004). Oncogene 23: 4536-4555.
61. Villar-Garea A, Esteller M. (2004). Int J Cancer 112: 171-178.
62. Wang Z, Juttermann R, Soloway PD. (2000). J Biol Chem 275: 26411-26415.
63. Watnick RS, Cheng YN, Rangarajan A, Ince TA, Weinberg RA. (2003). Cancer Cell 3: 219-231.
64. Wei G, Schaffner AE, Baker KM, Mansky KC, Ostrowski MC. (2003). Anticancer Res 23: 2173-2178.
65. Wolthuis RM, Bos JL. (1999). Curr Opin Genet Dev 9: 112-117.
66. Zhou X, Richon VM, Wang AH, Yang XJ, Rifkind RA, Marks PA. (2000). Proc Natl Acad Sci USA 97: 14329-14333.
67. Zohn IM, Campbell SL, Khosravi-Far R, Rossman KL, Der CJ. (1998). Oncogene 17: 1415-1438.
68. Zuber J, Tchernitsa OI, Hinzmann B, Schmitz AC, Grips M, Hellriegel M et al. (2000). Nat Genet 24: 144-152.