A mouse model of breast cancer metastasis to the choroid of the eye

Clinical and Experimental Metastasis

Volumn 22, Issue 8, 2005, Pages 685-690

  Kuhn, Misty ^a   Shah, Sarah ^a   Natasha, Tajneen ^a   Rittling, Susan R ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b FORSYTH INSTITUTE   (United States)

Author keywords

Brain metastasis; Breast cancer; Choroidal metastases; Mouse model; Uveal metastasis

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL CULTURE; CANCER MODEL; CHOROID CANCER; CONTROLLED STUDY; FEMALE; MALE; METASTASIS; MOUSE; MOUSE STRAIN; NONHUMAN; OPTIC NERVE; PIGMENT CELL; PIGMENTATION; UVEA;

ANIMALS; BREAST NEOPLASMS; CHOROID NEOPLASMS; DISEASE MODELS, ANIMAL; FEMALE; MALE; MICE; MICE, INBRED C57BL;

EID: 33747507303     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-006-9012-3     Document Type: Article

References (20)

1. American Cancer Society (2005) Cancer facts and figures 2005. American Cancer Society, Atlanta
2. Weigelt B, Peterse JL, van't Veer LJ (2005) Breast cancer metastasis: markers and models. Nat Rev Cancer 5(8):591-602
3. Shields CL, Shields JA, Gross NE, Schwartz GP, Lally SE (1997) Survey of 520 eyes with uveal metastases. Ophthalmology 104(8):1265-1276
4. Wiegel T, Kreusel KM, Bornfeld N, Bottke D, Stange M, Foerster MH et al (1998) Frequency of asymptomatic choroidal metastasis in patients with disseminated breast cancer: results of a prospective screening programme. Br J Ophthalmol 82(10):1159-1161
5. Chong JT, Mick A (2005) Choroidal metastasis: case reports and review of the literature. Optometry 76(5):293-301
6. Char DH, Miller T, Kroll S (1997) Orbital metastases: diagnosis and course. Br J Ophthalmol 81(5):386-390
7. Fenton S, Kemp EG, Harnett AN (2004) Screening for ophthalmic involvement in asymptomatic patients with metastatic breast carcinoma. Eye 18(1):38-40
8. Damato B (2004) Developments in the management of uveal melanoma. Clin Experiment Ophthalmol 32(6):639-647
9. Tsina EK, Lane AM, Zacks DN, Munzenrider JE, Collier JM, Gragoudas ES (2005) Treatment of metastatic tumors of the choroid with proton beam irradiation. Ophthalmology 112(2):337-343
10. Chen Y, Rittling SR (2003) Novel murine mammary epithelial cell lines that form osteolytic bone metastases: effect of strain background on tumor homing. Clin Exp Metastasis 20(2):111-120
11. Natasha T, Kuhn M, Kelly O, Rittling SR (2006) Override of the osteoclast defect in osteopontin-deficient mice by metastatic tumor growth in the bone. Am J Pathol 168(2):551-561
12. Nicolson GL (1993) Paracrine and autocrine growth mechanisms in tumor metastasis to specific sites with particular emphasis on brain and lung metastasis. Cancer Metastasis Rev 12(3-4):325-343
13. Hochman J, Assaf N, Deckert-Schluter M, Wiestler OD, Pe'er J (2001) Entry routes of malignant lymphoma into the brain and eyes in a mouse model. Cancer Res 61(13):5242-5247
14. Sutton R, Gordon-Thomson C, Cree IA, Mason RS, Moore GP (2002) Tyr-TGFalpha transgenic mice develop ocular melanocytic lesions. Melanoma Res 12(5):435-439
15. Tolleson WH, Doss JC, Latendresse J, Warbritton AR, Melchior WB Jr, Chin L et al (2005) Spontaneous uveal a-melanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/-mice. Arch Ophthalmol 123(8):1088-1094
16. Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME et al (2001) Involvement of chemokine receptors in breast cancer metastasis. Nature 410(6824):50-56
17. Taichman RS, Cooper C, Keller ET, Pienta KJ, Taichman NS, McCauley LK (2002) Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res 62(6):1832-1837
18. Chambers AF, Groom AC, MacDonald IC (2002) Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2(8):563-572
19. Bhutto IA, Amemiya T (2001) Microvascular architecture of the rat choroid: corrosion cast study. Anat Rec 264(1):63-71
20. Ruoslahti E (2004) Vascular zip codes in angiogenesis and metastasis. Biochem Soc Trans 32(Pt3):397-402