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Volumn 330, Issue 6, 2005, Pages 326-335

Nonalcoholic steatohepatitis and the metabolic syndrome

Author keywords

Alanine aminotransferase; Cirrhosis; Fatty liver; Insulin resistance; Liver biopsy

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CORTICOSTEROID; GLITAZONE DERIVATIVE; HEPATITIS A VACCINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METFORMIN; PIOGLITAZONE; ROSIGLITAZONE; TROGLITAZONE; URSODEOXYCHOLIC ACID;

EID: 29244444549     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000441-200512000-00011     Document Type: Conference Paper
Times cited : (169)

References (93)
  • 1
    • 0035083842 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Definition and pathology
    • Brunt EM. Nonalcoholic steatohepatitis: definition and pathology. Semin Liver Dis 2001;21:3-16.
    • (2001) Semin Liver Dis , vol.21 , pp. 3-16
    • Brunt, E.M.1
  • 2
    • 1942454793 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis
    • Brunt EM. Nonalcoholic steatohepatitis. Semin Liver Dis 2004;24:3-20.
    • (2004) Semin Liver Dis , vol.24 , pp. 3-20
    • Brunt, E.M.1
  • 3
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
    • Matteoni CA, Younossi ZM, Gramlich T, et al. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999;116:1413-9.
    • (1999) Gastroenterology , vol.116 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Gramlich, T.3
  • 4
    • 0035085853 scopus 로고    scopus 로고
    • Clinical features and natural history of nonalcoholic steatosis syndromes
    • Falck-Ytter Y, Younossi ZM, Marchesini G, et al. Clinical features and natural history of nonalcoholic steatosis syndromes. Semin Liver Dis 2001;21:17-26.
    • (2001) Semin Liver Dis , vol.21 , pp. 17-26
    • Falck-Ytter, Y.1    Younossi, Z.M.2    Marchesini, G.3
  • 5
    • 0037221394 scopus 로고    scopus 로고
    • Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States
    • Ruhl CE, Everhart JE. Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. Gastroenterology 2003;124:71-9.
    • (2003) Gastroenterology , vol.124 , pp. 71-79
    • Ruhl, C.E.1    Everhart, J.E.2
  • 6
    • 4344582117 scopus 로고    scopus 로고
    • Epidemiology of nonalcoholic fatty liver
    • Ruhl CE, Everhart JE. Epidemiology of nonalcoholic fatty liver. Clin Liver Dis 2004;8:501-19.
    • (2004) Clin Liver Dis , vol.8 , pp. 501-519
    • Ruhl, C.E.1    Everhart, J.E.2
  • 7
    • 0033767987 scopus 로고    scopus 로고
    • Characterization of pathogenic and prognostic factors of non-alcoholic steatohepatitis associated with obesity
    • García-Monzón C, Martín-Pérez E, Iacono OL, et al. Characterization of pathogenic and prognostic factors of non-alcoholic steatohepatitis associated with obesity. J Hepatol 2000;33:716-24.
    • (2000) J Hepatol , vol.33 , pp. 716-724
    • García-Monzón, C.1    Martín-Pérez, E.2    Iacono, O.L.3
  • 8
    • 4344662384 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease in the pediatric population
    • Lavine JE, Schwimmer JB. Nonalcoholic fatty liver disease in the pediatric population. Clin Liver Dis 2004;8:549-58.
    • (2004) Clin Liver Dis , vol.8 , pp. 549-558
    • Lavine, J.E.1    Schwimmer, J.B.2
  • 9
    • 0025260531 scopus 로고
    • Fatty liver hepatitis (steatohepatitis) and obesity: An autopsy study with analysis of risk factors
    • Wanless IR, Lentz JS. Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors. Hepatology 1990;12:1106-10.
    • (1990) Hepatology , vol.12 , pp. 1106-1110
    • Wanless, I.R.1    Lentz, J.S.2
  • 10
    • 0034068984 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: Association with obesity and insulin resistance, and influence of weight loss
    • Luyckx FH, Lefebvre PJ, Scheen AJ. Non-alcoholic steatohepatitis: association with obesity and insulin resistance, and influence of weight loss. Diabetes Metab 2000;26:98-106.
    • (2000) Diabetes Metab , vol.26 , pp. 98-106
    • Luyckx, F.H.1    Lefebvre, P.J.2    Scheen, A.J.3
  • 11
    • 0034799113 scopus 로고    scopus 로고
    • Ninety patients with nonalcoholic steatohepatitis: Insulin resistance, familial tendency, and severity of disease
    • Willner IR, Waters B, Patil SR, et al. Ninety patients with nonalcoholic steatohepatitis: insulin resistance, familial tendency, and severity of disease. Am J Gastroenterol 2001;96:2957-61.
    • (2001) Am J Gastroenterol , vol.96 , pp. 2957-2961
    • Willner, I.R.1    Waters, B.2    Patil, S.R.3
  • 12
    • 0034950652 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese
    • Dixon JB, Bhathal PS, O'Brien PE. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology 2001;121:91-100.
    • (2001) Gastroenterology , vol.121 , pp. 91-100
    • Dixon, J.B.1    Bhathal, P.S.2    O'Brien, P.E.3
  • 13
    • 0035084699 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
    • Sanyal AJ, Campbell-Sargent C, Mirshani F, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001;120:1183-92.
    • (2001) Gastroenterology , vol.120 , pp. 1183-1192
    • Sanyal, A.J.1    Campbell-Sargent, C.2    Mirshani, F.3
  • 14
    • 18244364864 scopus 로고    scopus 로고
    • NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome
    • Chitturi S, Abeygunasekera S, Farrell GC, et al. NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 2002;35:373-9.
    • (2002) Hepatology , vol.35 , pp. 373-379
    • Chitturi, S.1    Abeygunasekera, S.2    Farrell, G.C.3
  • 15
    • 18244385511 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association
    • Pagano G, Pacini G, Musso G, et al. Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: further evidence for an etiologic association. Hepatology 2002;35:367-72.
    • (2002) Hepatology , vol.35 , pp. 367-372
    • Pagano, G.1    Pacini, G.2    Musso, G.3
  • 16
    • 0041571837 scopus 로고    scopus 로고
    • Metabolic and anthropometric evaluation of insulin resistance in nondiabetic patients with nonalcoholic steatohepatitis
    • Chalasani N, Deeg MA, Persohn S, et al. Metabolic and anthropometric evaluation of insulin resistance in nondiabetic patients with nonalcoholic steatohepatitis. Am J Gastroenterol 2003;98:1849-55.
    • (2003) Am J Gastroenterol , vol.98 , pp. 1849-1855
    • Chalasani, N.1    Deeg, M.A.2    Persohn, S.3
  • 17
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
    • Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology 2003;37:1202-19.
    • (2003) Hepatology , vol.37 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 18
    • 0141890172 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver: A common manifestation of a metabolic disorder
    • Malnick SD, Beergabel M, Knobler H. Non-alcoholic fatty liver: a common manifestation of a metabolic disorder. QJM 2003;96:699-709.
    • (2003) QJM , vol.96 , pp. 699-709
    • Malnick, S.D.1    Beergabel, M.2    Knobler, H.3
  • 19
    • 0035136312 scopus 로고    scopus 로고
    • Metabolic correlates of eating behavior in severe obesity
    • Kral JG, Buckley MC, Kissileff HR, et al. Metabolic correlates of eating behavior in severe obesity. Int J Obesity 2001;25:258-64.
    • (2001) Int J Obesity , vol.25 , pp. 258-264
    • Kral, J.G.1    Buckley, M.C.2    Kissileff, H.R.3
  • 20
    • 1542510700 scopus 로고    scopus 로고
    • Acquired and inherited lipodystrophies
    • Garg A. Acquired and inherited lipodystrophies. N Engl J Med 2004;350:1220-34.
    • (2004) N Engl J Med , vol.350 , pp. 1220-1234
    • Garg, A.1
  • 21
    • 12244284662 scopus 로고    scopus 로고
    • Concurrence of histologic features of steatohepatitis with other forms of chronic liver disease
    • Brunt EM, Ramrakhiani S, Cordes BG, et al. Concurrence of histologic features of steatohepatitis with other forms of chronic liver disease. Mod Pathol 2003;16:49-56.
    • (2003) Mod Pathol , vol.16 , pp. 49-56
    • Brunt, E.M.1    Ramrakhiani, S.2    Cordes, B.G.3
  • 22
    • 0031913573 scopus 로고    scopus 로고
    • Liver abnormalities in severely obese subjects: Effect of drastic weight loss after gastroplasty
    • Luyckx FH, Desaive C, Thiry A, et al. Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty. Int J Obes Relat Metab Disord 1998;22:222-6.
    • (1998) Int J Obes Relat Metab Disord , vol.22 , pp. 222-226
    • Luyckx, F.H.1    Desaive, C.2    Thiry, A.3
  • 23
    • 85081150879 scopus 로고    scopus 로고
    • The elusiveness of "normal" ALT in fatty liver
    • Ratziu V, Imbert-Bismut F, Messous D, et al. The elusiveness of "normal" ALT in fatty liver. Hepatology 2004;39:1172-3.
    • (2004) Hepatology , vol.39 , pp. 1172-1173
    • Ratziu, V.1    Imbert-Bismut, F.2    Messous, D.3
  • 24
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 2003;98:960-7.
    • (2003) Am J Gastroenterol , vol.98 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 25
    • 0037008087 scopus 로고    scopus 로고
    • Updated definitions of healthy ranges for serum alanine aminotransferase levels
    • Prati D, Taioli E, Zanella A, et al. Updated definitions of healthy ranges for serum alanine aminotransferase levels. Ann Intern Med 2002;137:1-9.
    • (2002) Ann Intern Med , vol.137 , pp. 1-9
    • Prati, D.1    Taioli, E.2    Zanella, A.3
  • 26
    • 0037008076 scopus 로고    scopus 로고
    • Alanine aminotransferase levels: What's normal?
    • Kaplan MM. Alanine aminotransferase levels: what's normal? Ann Intern Med 2002;137:49-51.
    • (2002) Ann Intern Med , vol.137 , pp. 49-51
    • Kaplan, M.M.1
  • 27
    • 0024468142 scopus 로고
    • Is liver biopsy useful in the evaluation of patients with chronically elevated liver enzymes?
    • Van Ness MM, Diehl AM. Is liver biopsy useful in the evaluation of patients with chronically elevated liver enzymes? Ann Intern Med 1989;111:473-8.
    • (1989) Ann Intern Med , vol.111 , pp. 473-478
    • Van Ness, M.M.1    Diehl, A.M.2
  • 28
    • 0033119425 scopus 로고    scopus 로고
    • The ratio of aspartate aminotransferase to alanine aminotransferase: Potential value in differentiating nonalcoholic steatohepatitis from alcoholic liver disease
    • Sorbi D, Boynton J, Lindor KD. The ratio of aspartate aminotransferase to alanine aminotransferase: potential value in differentiating nonalcoholic steatohepatitis from alcoholic liver disease. Am J Gastroenterol 1999;94:1018-22.
    • (1999) Am J Gastroenterol , vol.94 , pp. 1018-1022
    • Sorbi, D.1    Boynton, J.2    Lindor, K.D.3
  • 29
    • 9144258000 scopus 로고    scopus 로고
    • Non-organ-specific autoantibodies in nonalcoholic fatty liver disease: Prevalence and correlates
    • Loria P, Lonardo A, Leonardi F, et al. Non-organ-specific autoantibodies in nonalcoholic fatty liver disease: prevalence and correlates. Dig Dis Sci 2003;48:2173-81.
    • (2003) Dig Dis Sci , vol.48 , pp. 2173-2181
    • Loria, P.1    Lonardo, A.2    Leonardi, F.3
  • 30
    • 0034876150 scopus 로고    scopus 로고
    • Liver biopsy in elevated liver functions tests? An old question revisited
    • Bianchi L. Liver biopsy in elevated liver functions tests? An old question revisited. J Hepatol 2001;35:290-4.
    • (2001) J Hepatol , vol.35 , pp. 290-294
    • Bianchi, L.1
  • 31
    • 0033008248 scopus 로고    scopus 로고
    • The clinical significance of slightly to moderately increased liver transaminase values in asymptomatic patients
    • Mathiesen UL, Franzén LE, Frydén A, et al. The clinical significance of slightly to moderately increased liver transaminase values in asymptomatic patients. Scand J Gastroenterol 1999;34:85-91.
    • (1999) Scand J Gastroenterol , vol.34 , pp. 85-91
    • Mathiesen, U.L.1    Franzén, L.E.2    Frydén, A.3
  • 32
    • 0034720287 scopus 로고    scopus 로고
    • Evaluation of abnormal liver-enzyme results in asymptomatic patients
    • Pratt DS, Kaplan MM. Evaluation of abnormal liver-enzyme results in asymptomatic patients. N Engl J Med 2000;342:1266-71.
    • (2000) N Engl J Med , vol.342 , pp. 1266-1271
    • Pratt, D.S.1    Kaplan, M.M.2
  • 33
    • 0034862590 scopus 로고    scopus 로고
    • Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology
    • Skelly MM, James PD, Ryder SD. Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology. J Hepatol 2001;35:195-9.
    • (2001) J Hepatol , vol.35 , pp. 195-199
    • Skelly, M.M.1    James, P.D.2    Ryder, S.D.3
  • 34
    • 0033761248 scopus 로고    scopus 로고
    • An assessment of the role of liver biopsies in asymptomatic patients with chronic liver test abnormalities
    • Sorbi D, McGill DB, Thistle JL, et al. An assessment of the role of liver biopsies in asymptomatic patients with chronic liver test abnormalities. Am J Gastroenterol 2000;95:3206-10.
    • (2000) Am J Gastroenterol , vol.95 , pp. 3206-3210
    • Sorbi, D.1    McGill, D.B.2    Thistle, J.L.3
  • 36
    • 0034971950 scopus 로고    scopus 로고
    • Imaging of diffuse liver disease
    • Mortele KJ, Ros PR. Imaging of diffuse liver disease. Sem Liver Dis 2001;21:195-212.
    • (2001) Sem Liver Dis , vol.21 , pp. 195-212
    • Mortele, K.J.1    Ros, P.R.2
  • 37
    • 0036729447 scopus 로고    scopus 로고
    • The utility of radiological imaging in nonalcoholic fatty liver disease
    • Saadeh S, Younossi ZM, Remer EM, et al. The utility of radiological imaging in nonalcoholic fatty liver disease. Gastroenterology 2002;123:745-50.
    • (2002) Gastroenterology , vol.123 , pp. 745-750
    • Saadeh, S.1    Younossi, Z.M.2    Remer, E.M.3
  • 38
    • 0031753895 scopus 로고    scopus 로고
    • Diagnostic criteria for fatty infiltration of the liver on contrast-enhanced helical CT
    • Jacobs JE, Birnbaum BA, Shapiro MA, et al. Diagnostic criteria for fatty infiltration of the liver on contrast-enhanced helical CT. AJR Am J Roentgenol 1998;171:659-64.
    • (1998) AJR Am J Roentgenol , vol.171 , pp. 659-664
    • Jacobs, J.E.1    Birnbaum, B.A.2    Shapiro, M.A.3
  • 39
    • 0033635205 scopus 로고    scopus 로고
    • Focal fatty infiltration in the posterior aspect of hepatic segment IV: Relationship to pancreaticoduodenal venous drainage
    • Fukukura Y, Fujiyoshi F, Inoue H, et al. Focal fatty infiltration in the posterior aspect of hepatic segment IV: relationship to pancreaticoduodenal venous drainage. Am J Gastroenterol 2000;95:3590-5.
    • (2000) Am J Gastroenterol , vol.95 , pp. 3590-3595
    • Fukukura, Y.1    Fujiyoshi, F.2    Inoue, H.3
  • 40
    • 0029239789 scopus 로고
    • Focal sparing of liver parenchyma in steatosis: Role of the gallbladder and its vessels
    • Aubin B, Denys A, Lafortune M, et al. Focal sparing of liver parenchyma in steatosis: role of the gallbladder and its vessels. J Ultrasound Med 1995;14:77-80.
    • (1995) J Ultrasound Med , vol.14 , pp. 77-80
    • Aubin, B.1    Denys, A.2    Lafortune, M.3
  • 41
    • 0029900940 scopus 로고    scopus 로고
    • Hepatic pseudolesion around the falciform ligament: Prevalence on CT examination
    • Soyer P, Devine N, Somveille E, et al. Hepatic pseudolesion around the falciform ligament: prevalence on CT examination. Abdom Imaging 1996;21:324-8.
    • (1996) Abdom Imaging , vol.21 , pp. 324-328
    • Soyer, P.1    Devine, N.2    Somveille, E.3
  • 42
    • 0043268063 scopus 로고    scopus 로고
    • Long-term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C
    • Hui JM, Kench J, Chitturi S, et al. Long-term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C. Hepatology 2003;38:420-7.
    • (2003) Hepatology , vol.38 , pp. 420-427
    • Hui, J.M.1    Kench, J.2    Chitturi, S.3
  • 43
    • 4344628555 scopus 로고    scopus 로고
    • The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease
    • McCullough AJ. The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease. Clin Liver Dis 2004;8:521-33.
    • (2004) Clin Liver Dis , vol.8 , pp. 521-533
    • McCullough, A.J.1
  • 44
    • 0141594639 scopus 로고    scopus 로고
    • Is obesity a risk factor for cirrhosis-related death or hospitalization? a population-based cohort study
    • Ioannou GN, Weiss NS, Kowdley KV, et al. Is obesity a risk factor for cirrhosis-related death or hospitalization? A population-based cohort study. Gastroenterology 2003;125:1053-9.
    • (2003) Gastroenterology , vol.125 , pp. 1053-1059
    • Ioannou, G.N.1    Weiss, N.S.2    Kowdley, K.V.3
  • 45
    • 7244250409 scopus 로고    scopus 로고
    • Silent non-alcoholic fatty liver disease - A clinical-histological study
    • Sorrentino P, Tarantino G, Conca P, et al. Silent non-alcoholic fatty liver disease - a clinical-histological study. J Hepatol 2004;41:751-7.
    • (2004) J Hepatol , vol.41 , pp. 751-757
    • Sorrentino, P.1    Tarantino, G.2    Conca, P.3
  • 46
    • 1642355723 scopus 로고    scopus 로고
    • The spectrum expanded: Cryptogenic cirrhosis and the natural history of non-alcoholic fatty liver disease
    • Caldwell S, Crespo DM. The spectrum expanded: cryptogenic cirrhosis and the natural history of non-alcoholic fatty liver disease. J Hepatol 2004;40:578-84.
    • (2004) J Hepatol , vol.40 , pp. 578-584
    • Caldwell, S.1    Crespo, D.M.2
  • 47
    • 0038142845 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: An underrecognized cause of cryptogenic cirrhosis
    • Clark JM, Diehl AM. Nonalcoholic fatty liver disease: an underrecognized cause of cryptogenic cirrhosis. JAMA 2003;289:3000-4.
    • (2003) JAMA , vol.289 , pp. 3000-3004
    • Clark, J.M.1    Diehl, A.M.2
  • 48
    • 0033797838 scopus 로고    scopus 로고
    • Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: A case-control study
    • Poonawala A, Nair SP, Thuluvath PJ. Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study. Hepatology 2000;32:689-92.
    • (2000) Hepatology , vol.32 , pp. 689-692
    • Poonawala, A.1    Nair, S.P.2    Thuluvath, P.J.3
  • 49
    • 0038471763 scopus 로고    scopus 로고
    • Obesity and cryptogenic cirrhosis
    • Leuschner U, James O, Dancygier H, editors. Norwell, MA: Kluwer Academic Publishers
    • Caldwell SH, Hespenheide EE. Obesity and cryptogenic cirrhosis. In: Leuschner U, James O, Dancygier H, editors. Steatohepatitis (ASH and NASH). Falk Symposium 121. Norwell, MA: Kluwer Academic Publishers; 2001. p. 151.
    • (2001) Steatohepatitis (ASH and NASH). Falk Symposium 121 , pp. 151
    • Caldwell, S.H.1    Hespenheide, E.E.2
  • 50
    • 0034843450 scopus 로고    scopus 로고
    • Cryptogenic cirrhosis and posttransplantation nonalcoholic fatty liver disease
    • Ong J, Younossi ZM, Reddy V, et al. Cryptogenic cirrhosis and posttransplantation nonalcoholic fatty liver disease. Liver Transpl 2001;7:797-801.
    • (2001) Liver Transpl , vol.7 , pp. 797-801
    • Ong, J.1    Younossi, Z.M.2    Reddy, V.3
  • 51
    • 0035052345 scopus 로고    scopus 로고
    • Development of nonalcoholic fatty liver disease after orthotopic liver transplantation for cryptogenic cirrhosis
    • Contos MJ, Cales W, Sterling RK, et al. Development of nonalcoholic fatty liver disease after orthotopic liver transplantation for cryptogenic cirrhosis. Liver Transpl 2001;7:363-73.
    • (2001) Liver Transpl , vol.7 , pp. 363-373
    • Contos, M.J.1    Cales, W.2    Sterling, R.K.3
  • 52
    • 18544365700 scopus 로고    scopus 로고
    • Survival, liver failure, and hepatocellular carcinoma in obesity-related cryptogenic cirrhosis
    • Ratziu V, Bonyhay L, Di Martino V, et al. Survival, liver failure, and hepatocellular carcinoma in obesity-related cryptogenic cirrhosis. Hepatology 2002;35:1485-93.
    • (2002) Hepatology , vol.35 , pp. 1485-1493
    • Ratziu, V.1    Bonyhay, L.2    Di Martino, V.3
  • 53
    • 0036288123 scopus 로고    scopus 로고
    • Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis?
    • Nair S, Mason A, Eason J, et al. Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis? Hepatology 2002;36:150-5.
    • (2002) Hepatology , vol.36 , pp. 150-155
    • Nair, S.1    Mason, A.2    Eason, J.3
  • 54
    • 0036894480 scopus 로고    scopus 로고
    • NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States
    • Marrero JA, Fontana RJ, Su GI, et al. NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States. Hepatology 2002;36:1349-54.
    • (2002) Hepatology , vol.36 , pp. 1349-1354
    • Marrero, J.A.1    Fontana, R.J.2    Su, G.I.3
  • 55
    • 0842321807 scopus 로고    scopus 로고
    • Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma
    • El-Serag HB, Tran T, Everhart JE. Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology 2004;126:460-8.
    • (2004) Gastroenterology , vol.126 , pp. 460-468
    • El-Serag, H.B.1    Tran, T.2    Everhart, J.E.3
  • 56
    • 0038613571 scopus 로고    scopus 로고
    • Is hepatocellular carcinoma part of the natural history of nonalcoholic steatohepatitis?
    • Anagnostopoulos GK, Arvanitidis D, Tsiakos S, et al. Is hepatocellular carcinoma part of the natural history of nonalcoholic steatohepatitis? J Clin Gastroenterol 2003;37:88-9.
    • (2003) J Clin Gastroenterol , vol.37 , pp. 88-89
    • Anagnostopoulos, G.K.1    Arvanitidis, D.2    Tsiakos, S.3
  • 57
    • 4143065907 scopus 로고    scopus 로고
    • Synergism of alcohol, diabetes, and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the U.S.
    • Yuan J-M, Govindarajan S, Arakawa K, et al. Synergism of alcohol, diabetes, and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the U.S. Cancer 2004;101:1009-17.
    • (2004) Cancer , vol.101 , pp. 1009-1017
    • Yuan, J.-M.1    Govindarajan, S.2    Arakawa, K.3
  • 58
    • 0032695030 scopus 로고    scopus 로고
    • Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
    • Angulo P, Keach JC, Batts KP, et al. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 1999;30:1356-62.
    • (1999) Hepatology , vol.30 , pp. 1356-1362
    • Angulo, P.1    Keach, J.C.2    Batts, K.P.3
  • 59
    • 0031799747 scopus 로고    scopus 로고
    • Hepatic steatosis: Innocent bystander or guilty party?
    • Day CP, James OF. Hepatic steatosis: innocent bystander or guilty party? Hepatology 1998;27:1463-6.
    • (1998) Hepatology , vol.27 , pp. 1463-1466
    • Day, C.P.1    James, O.F.2
  • 60
    • 0033913793 scopus 로고    scopus 로고
    • Hepatic stellate cell activation in nonalcoholic steatohepatitis and fatty liver
    • Washington K, Wright K, Shyr Y, et al. Hepatic stellate cell activation in nonalcoholic steatohepatitis and fatty liver. Hum Pathol 2000;31:822-8.
    • (2000) Hum Pathol , vol.31 , pp. 822-828
    • Washington, K.1    Wright, K.2    Shyr, Y.3
  • 61
    • 0035102486 scopus 로고    scopus 로고
    • Hepatic stellate cell activation occurs in nonalcoholic steatohepatitis
    • Cortez-Pinto H, Baptista A, Camilo ME, et al. Hepatic stellate cell activation occurs in nonalcoholic steatohepatitis. Hepatogastroenterol 2001;48:87-90.
    • (2001) Hepatogastroenterol , vol.48 , pp. 87-90
    • Cortez-Pinto, H.1    Baptista, A.2    Camilo, M.E.3
  • 62
    • 0034802171 scopus 로고    scopus 로고
    • High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis
    • Paradis V, Perlemuter G, Bonvoust F, et al. High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis. Hepatology 2001;34:738-44.
    • (2001) Hepatology , vol.34 , pp. 738-744
    • Paradis, V.1    Perlemuter, G.2    Bonvoust, F.3
  • 63
    • 0023589362 scopus 로고
    • Perisinusoidal fibrosis and basement membrane-like material in the livers of diabetic patients
    • Latry P, Bioulac-Sage P, Echinard E, et al. Perisinusoidal fibrosis and basement membrane-like material in the livers of diabetic patients. Hum Pathol 1987;18:775-80.
    • (1987) Hum Pathol , vol.18 , pp. 775-780
    • Latry, P.1    Bioulac-Sage, P.2    Echinard, E.3
  • 64
    • 0033329864 scopus 로고    scopus 로고
    • Liver pathology and the metabolic syndrome X in severe obesity
    • Marceau P, Biron S, Hould F-S, et al. Liver pathology and the metabolic syndrome X in severe obesity. J Clin Endocrinol Metab 1999;84:1513-7.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1513-1517
    • Marceau, P.1    Biron, S.2    Hould, F.-S.3
  • 65
    • 0035085858 scopus 로고    scopus 로고
    • Treatment of nonalcoholic fatty liver: Present and emerging therapies
    • Angulo P, Lindor KD. Treatment of nonalcoholic fatty liver: present and emerging therapies. Sem Liver Dis 2001;21:81-8.
    • (2001) Sem Liver Dis , vol.21 , pp. 81-88
    • Angulo, P.1    Lindor, K.D.2
  • 66
    • 1542515099 scopus 로고    scopus 로고
    • Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: Results of a randomized trial
    • Lindor KD, Kowdley KV, Heathcote EJ, et al. Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial. Hepatology 2004;39:770-8.
    • (2004) Hepatology , vol.39 , pp. 770-778
    • Lindor, K.D.1    Kowdley, K.V.2    Heathcote, E.J.3
  • 67
    • 0035799806 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    • Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001;344:1343-50.
    • (2001) N Engl J Med , vol.344 , pp. 1343-1350
    • Tuomilehto, J.1    Lindstrom, J.2    Eriksson, J.G.3
  • 68
    • 2542418066 scopus 로고    scopus 로고
    • Primary prevention of type 2 diabetes mellitus by lifestyle intervention: Implications for health policy
    • Center for Disease Control and Prevention Primary Prevention Working Group. Primary prevention of type 2 diabetes mellitus by lifestyle intervention: implications for health policy. Ann Intern Med 2004;140:951-7.
    • (2004) Ann Intern Med , vol.140 , pp. 951-957
  • 69
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002;346:393-403.
    • (2002) N Engl J Med , vol.346 , pp. 393-403
  • 70
    • 0037502809 scopus 로고    scopus 로고
    • Television watching and other sedentary behaviours in relation to risk of obesity and type 2 diabetes mellitus in women
    • Hu FB, Li TY, Colditz GA, et al. Television watching and other sedentary behaviours in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA 2003;289:1785-91.
    • (2003) JAMA , vol.289 , pp. 1785-1791
    • Hu, F.B.1    Li, T.Y.2    Colditz, G.A.3
  • 71
    • 0038517194 scopus 로고    scopus 로고
    • Concurrent exercise prevents high-fat-diet-induced macrovesicular hepatic steatosis
    • Gauthier MS, Couturier K, Latour JG, et al. Concurrent exercise prevents high-fat-diet-induced macrovesicular hepatic steatosis. J Appl Physiol 2003;94:2127-34.
    • (2003) J Appl Physiol , vol.94 , pp. 2127-2134
    • Gauthier, M.S.1    Couturier, K.2    Latour, J.G.3
  • 72
    • 0042265627 scopus 로고    scopus 로고
    • Cytokines and NASH: A pilot study of the effects of lifestyle modification and vitamin e
    • Kugelmas M, Hill DB, Vivian B, et al. Cytokines and NASH: a pilot study of the effects of lifestyle modification and vitamin E. Hepatology 2003;38:413-9.
    • (2003) Hepatology , vol.38 , pp. 413-419
    • Kugelmas, M.1    Hill, D.B.2    Vivian, B.3
  • 73
    • 0242361302 scopus 로고    scopus 로고
    • Is weight reduction an effective therapy for nonalcoholic fatty liver? a systematic review
    • Wang RT, Koretz RL, Yee HF, Jr. Is weight reduction an effective therapy for nonalcoholic fatty liver? A systematic review. Am J Med 2003;115:554-9.
    • (2003) Am J Med , vol.115 , pp. 554-559
    • Wang, R.T.1    Koretz, R.L.2    Yee Jr., H.F.3
  • 74
    • 0037737900 scopus 로고    scopus 로고
    • A randomized trial of a low-carbohydrate diet for obesity
    • Foster GD, Wyatt HR, Hill JO, et al. A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med 2003;348:2082-90.
    • (2003) N Engl J Med , vol.348 , pp. 2082-2090
    • Foster, G.D.1    Wyatt, H.R.2    Hill, J.O.3
  • 75
    • 0038751994 scopus 로고    scopus 로고
    • A low-carbohydrate as compared with a low-fat diet in severe obesity
    • Samaha FF, Iqbal N, Seshadri P, et al. A low-carbohydrate as compared with a low-fat diet in severe obesity. N Engl J Med 2003;348:2074-81.
    • (2003) N Engl J Med , vol.348 , pp. 2074-2081
    • Samaha, F.F.1    Iqbal, N.2    Seshadri, P.3
  • 76
    • 0038284646 scopus 로고    scopus 로고
    • Diet, obesity, and cardiovascular risk
    • Bonow RO, Eckel RH. Diet, obesity, and cardiovascular risk. N Engl J Med 2003;348:2057-8.
    • (2003) N Engl J Med , vol.348 , pp. 2057-2058
    • Bonow, R.O.1    Eckel, R.H.2
  • 77
    • 0242684706 scopus 로고    scopus 로고
    • Restoration of euglycemia and normal acute insulin response to glucose in obese subjects with type 2 diabetes following bariatric surgery
    • Polyzogopoulou EV, Kalfarentzos F, Vagenakis AG, et al. Restoration of euglycemia and normal acute insulin response to glucose in obese subjects with type 2 diabetes following bariatric surgery. Diabetes 2003;52:1098-103.
    • (2003) Diabetes , vol.52 , pp. 1098-1103
    • Polyzogopoulou, E.V.1    Kalfarentzos, F.2    Vagenakis, A.G.3
  • 78
    • 0035112424 scopus 로고    scopus 로고
    • Current status of medical and surgical therapy for obesity
    • Mun EC, Blackburn GL, Matthews JB. Current status of medical and surgical therapy for obesity. Gastroenterology 2001;120:669-81.
    • (2001) Gastroenterology , vol.120 , pp. 669-681
    • Mun, E.C.1    Blackburn, G.L.2    Matthews, J.B.3
  • 79
    • 1542285988 scopus 로고    scopus 로고
    • Surgery for severe obesity
    • Steinbrook R. Surgery for severe obesity. N Engl J Med 2004;350:1075-9.
    • (2004) N Engl J Med , vol.350 , pp. 1075-1079
    • Steinbrook, R.1
  • 80
    • 0025549042 scopus 로고
    • Regression of liver steatosis following gastroplasty or gastric bypass for morbid obesity
    • Ranløv I, Hardt F. Regression of liver steatosis following gastroplasty or gastric bypass for morbid obesity. Digestion 1990;47:208-14.
    • (1990) Digestion , vol.47 , pp. 208-214
    • Ranløv, I.1    Hardt, F.2
  • 82
    • 0035879150 scopus 로고    scopus 로고
    • Roux-en-Y gastric bypass for recurrent nonalcoholic steatohepatitis in liver transplant recipients with morbid obesity
    • Duchini A, Brunson ME. Roux-en-Y gastric bypass for recurrent nonalcoholic steatohepatitis in liver transplant recipients with morbid obesity. Transplantation 2001;72:156-71.
    • (2001) Transplantation , vol.72 , pp. 156-171
    • Duchini, A.1    Brunson, M.E.2
  • 83
    • 0348047323 scopus 로고    scopus 로고
    • Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis
    • Kral JG, Thung SN, Biron S, et al. Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis. Surgery 2004;135:48-58.
    • (2004) Surgery , vol.135 , pp. 48-58
    • Kral, J.G.1    Thung, S.N.2    Biron, S.3
  • 84
    • 3242745192 scopus 로고    scopus 로고
    • Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes
    • Tiikkainen M, Hakkinen A-M, Korsheninnikova E, et al. Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes. Diabetes 2004;53:2169-76.
    • (2004) Diabetes , vol.53 , pp. 2169-2176
    • Tiikkainen, M.1    Hakkinen, A.-M.2    Korsheninnikova, E.3
  • 85
    • 0035120396 scopus 로고    scopus 로고
    • A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis
    • Caldwell SH, Hespenheide EE, Redick JA, et al. A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis. Am J Gastroenterol 2001;96:519-25.
    • (2001) Am J Gastroenterol , vol.96 , pp. 519-525
    • Caldwell, S.H.1    Hespenheide, E.E.2    Redick, J.A.3
  • 86
    • 0141532275 scopus 로고    scopus 로고
    • Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-γ ligand rosiglitazone
    • Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, et al. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-γ ligand rosiglitazone. Hepatology 2003;38:1008-17.
    • (2003) Hepatology , vol.38 , pp. 1008-1017
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3
  • 87
    • 0141996322 scopus 로고    scopus 로고
    • Effect of pioglitazone on biochemical indices of non-alchoholic fatty liver disease in upper body obesity
    • Shadid S, Jensen MD. Effect of pioglitazone on biochemical indices of non-alchoholic fatty liver disease in upper body obesity. Clin Gastroenterol Hepatol 2003;1:384-7.
    • (2003) Clin Gastroenterol Hepatol , vol.1 , pp. 384-387
    • Shadid, S.1    Jensen, M.D.2
  • 88
    • 1442355447 scopus 로고    scopus 로고
    • A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis
    • Promrat K, Lutchman G, Uwaifo GI, et al. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology 2004;39:188-96.
    • (2004) Hepatology , vol.39 , pp. 188-196
    • Promrat, K.1    Lutchman, G.2    Uwaifo, G.I.3
  • 89
    • 0037385387 scopus 로고    scopus 로고
    • Interim results of a pilot study demonstrating the early effects of the PPAR-γ ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis
    • Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, et al. Interim results of a pilot study demonstrating the early effects of the PPAR-γ ligand rosiglitazone on insulin sensitivity, aminotransferases, hepatic steatosis and body weight in patients with non-alcoholic steatohepatitis. J Hepatol 2003;38:434-40.
    • (2003) J Hepatol , vol.38 , pp. 434-440
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3
  • 90
    • 0035883890 scopus 로고    scopus 로고
    • Metformin in non-alcoholic steatohepatitis
    • Marchesini G, Brizi M, Bianchi G, et al. Metformin in non-alcoholic steatohepatitis [letter]. Lancet 2001;358:893-4.
    • (2001) Lancet , vol.358 , pp. 893-894
    • Marchesini, G.1    Brizi, M.2    Bianchi, G.3
  • 91
    • 0034126755 scopus 로고    scopus 로고
    • Vitamin E treatment of nonalcoholic steatohepatitis in children: A pilot study
    • Lavine JE. Vitamin E treatment of nonalcoholic steatohepatitis in children: a pilot study. J Pediatr 2000;136:734-8.
    • (2000) J Pediatr , vol.136 , pp. 734-738
    • Lavine, J.E.1
  • 92
    • 0344742265 scopus 로고    scopus 로고
    • Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis
    • Harrison SA, Torgerson S, Hayashi P, et al. Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis. Am J Gastroenterol 2003;98:2485-90.
    • (2003) Am J Gastroenterol , vol.98 , pp. 2485-2490
    • Harrison, S.A.1    Torgerson, S.2    Hayashi, P.3
  • 93
    • 2142768218 scopus 로고    scopus 로고
    • Patients with elevated liver enzymes are not at higher risk for statin hepatotoxicity
    • Chalasani N, Aljadhey H, Kesterson J, et al. Patients with elevated liver enzymes are not at higher risk for statin hepatotoxicity. Gastroenterology 2004;126:1287-92.
    • (2004) Gastroenterology , vol.126 , pp. 1287-1292
    • Chalasani, N.1    Aljadhey, H.2    Kesterson, J.3


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