Activation of Telomerase by Ionizing Radiation: Differential Response to the Inhibition of DNA Double-Strand Break Repair by Abrogation of Poly(ADP-ribosyl)ation, by LY294002, or by Wortmannin

International Journal of Radiation Oncology Biology Physics

Volumn 69, Issue 3, 2007, Pages 887-894

  Neuhof, Dirk ^a   Zwicker, Felix ^a   Kuepper, Jan Heiner ^b   Debus, Juergen ^a   Weber, Klaus Josef ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Heart BioSystems GmbH   (Germany)

Author keywords

Double strand breaks; Irradiation; LY294002; Telomerase; Wortmannin

Indexed keywords

AMIDES; DNA; IONIZING RADIATION; PATIENT TREATMENT; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

DOUBLE STRAND BREAKS; POLYMERASE CHAIN REACTIONS; TELOMERASE; WORTMANNIN;

ENZYME ACTIVITY;

2 MORPHOLINO 8 PHENYLCHROMONE; 3 AMINOBENZAMIDE; DEXAMETHASONE; DOUBLE STRANDED DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE C; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; WORTMANNIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME MECHANISM; ENZYME REPRESSION; GENE OVEREXPRESSION; IONIZING RADIATION; IRRADIATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RADIATION DOSE; RAT; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ANDROSTADIENES; ANIMALS; BENZAMIDES; CELL LINE; CHROMONES; DEXAMETHASONE; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; ENZYME ACTIVATION; ENZYME INHIBITORS; MORPHOLINES; PHOSPHORYLATION; POLY ADENOSINE DIPHOSPHATE RIBOSE; PROTEIN KINASE C; PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TELOMERASE; UP-REGULATION;

EID: 34548690114     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.06.051     Document Type: Article

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