Regulation of telomerase activity in immortal cell lines

Molecular and Cellular Biology

Volumn 16, Issue 6, 1996, Pages 2932-2939

  Holt, Shawn E ^a   Wright, Woodring E ^a   Shay, Jerry W ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; RNA DIRECTED DNA POLYMERASE;

ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL IMMORTALIZATION; DNA REPLICATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; TELOMERE;

EID: 0029973653     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.6.2932     Document Type: Article

References (36)

1. Allsopp, R. C., H. Vaziri, C. Patterson, S. Goldstein, E. V. Younglai, A. B. Futcher, C. W. Greider, and C. B. Harley. 1992. Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl. Acad. Sci. USA 89: 10114-10118.
2. Bacchetti, S., and C. M. Counter. 1995. Telomeres and telomerase in human cancer. Int. J. Oncol. 7:423-432.
3. Boccaccio, C., G. Gaudino, G. Gambarotta, F. Galimi, and P. M. Comoglio. 1994. Hepatocyte growth factor (HGF) receptor expression is inducible and is part of the delayed-early response to HGF. J. Biol. Chem. 269:12846-12851.
4. Broccoli, D., J. W. Young, and T. de Lange. 1995. Telomerase activity in normal and malignant hematopoietic cells. Proc. Natl. Acad. Sci. USA 92: 9082-9086.
5. Chiu, C.-P., W. Dragowska, N. W. Kim, H. Vaziri, J. Yui, T. E. Thomas, C. B. Harley, and P. M. Landsorp. 1996. Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells 14:239-248.
6. Counter, C. M., A. A. Avilion, C. E. LeFeuvre, N. G. Stewart, C. W. Greider, C. B. Harley, and S. Bacchetti. 1992. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11:1921-1929.
7. Counter, C. M., H. W. Hirte, S. Bacchetti, and C. B. Harley. 1994. Telomerase activity in human ovarian carcinoma. Proc. Natl. Acad. Sci. USA 91:2900-2904.
8. de Lange, T. 1992. Human telomeres are attached to the nuclear matrix. EMBO J. 11:717-724.
9. Greider, C. W. 1994. Mammalian telomere dynamics: healing, fragmentation shortening and stabilization. Curr. Opin. Genet. Dev. 4:203-211.
10. Greider, C. W., and E. H. Blackburn. 1989. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature (London) 344:331-337.
11. Harley, C. B., A. B. Futcher, and C. W. Greider. 1990. Telomeres shorten during aging. Nature (London) 345:458-460.
12. Harley, C. B., and B. Villeponteau. 1995. Telomeres and telomerase in aging and cancer. Curr. Opin. Genet. Dev. 5:249-255.
13. Hiyama, E., K. Hiyama, T. Yokoyama, Y. Matsuura, M. A. Piatyszek, and J. W. Shay. 1995. Correlating telomerase activity levels with human neuroblastoma outcomes. Nat. Med. 1:249-255.
14. Hiyama, K., Y. Hirai, S. Kyoizumi, M. Akiyama, E. Hiyama, M. A. Piatyszek, J. W. Shay, S. Ishoika, and M. Yamakido. 1995. Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J. Immunol. 155: 3711-3715.
15. Hiyama, K., E. Hiyama, S. Ishoika, M. Yamakido, K. Inai, A. F. Gazdar, M. A. Piatyszek, and J. W. Shay. 1995. Telomerase activity in small-cell and non-small-cell lung cancers. J. Natl. Cancer Inst. 87:895-902.
16. Kim, N. W., M. A. Piatyszek, K. R. Prowse, C. B. Harley, M. D. West, P. L. C. Ho, G. M. Coviello, W. E. Wright, S. L. Weinrich, and J. W. Shay. 1994. Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011-2015.
17. Kioussi, C., and P. Grass. 1994. Differential induction of Pax genes by NGF and BDNF in cerebellar primary cultures. J. Cell Biol. 125:417-425.
18. Lundblad, V., and J. W. Szostak. 1989. A mutant with a defect in telomere elongation leads to senescence in yeast. Cell 57:633-643.
19. Mantell, L. L., and C. W. Greider. 1994. Telomerase activity in germline and embryonic cells of Xenopus. EMBO J. 13:3211-3217.
20. McCarthy, J. V., R. S. Fernandas, and T. G. Gotter. 1994. Increased resistance to apoptosis associated with HL-60 myeloid differentiation status. Anticancer Res. 14:2063-2074.
21. McEachern, M. J., and E. H. Blackburn. 1995, Runaway telomere elongation caused by telomerase RNA gene mutations. Science 376:403-409.,
22. n, present at the telomeres of human chromosomes. Proc. Natl. Acad. Sci. USA 85:6622-6626.
23. Piatyszek, M. A., N. W. Kim, S. L. Weinrich, K. Hiyama, E. Hiyama, W. E. Wright, and J. W. Shay. 1995. Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP). Methods Cell Sci. 17:1-15.
24. Prowse, K. R., and C. W. Greider. 1995. Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc. Natl. Acad. Sci. USA 92:4818-4822.
25. Sharma, H. W., J. A. Sokoloski, J. R. Perez, J. Y. Maltese, A. C. Sartorelli, C. A. Stein, G. Nichols, Z. Khaled, N. T. Telang, and R. Narayanan. 1995. Differentiation of immortal cells inhibits telomerase activity. Proc. Natl. Acad. Sci. USA 92:12343-12346.
26. Shay, J. W. 1995. Aging and cancer: are telomeres and telomerase the connection? Mol. Med. Today 1:378-384.
27. Singer, M. S., and D. E. Gottschling. 1994. TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 266:404-409.
28. Tahara, H., T. Nakanishi, M. Kitamoto, R. Nakashio, J. W. Shay, E. Tahara, G. Kajiyama, and T. Ide. 1995. Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas. Cancer Res. 55:2734-2736.
29. Watts, R. G. 1995. Role of gelsolin in the formation and organization of triton-soluble F-actin during myeloid differentiation of HL-60 cells. Blood 85:2212-2221.
30. 1-3 tails late in S phase. Cell 72:51-60.
31. Wright, W. E. 1982. The BrdU content of DNA is decreased during reversal of inhibition of myogenesis by deoxycytidine. Somatic Cell Genet. 8:547-555.
32. Wright, W. E., M. A. Piatyszek, W. E. Rainey, W. Byrd, and J. W. Shay. 1996. Telomerase activity in human germline and embryonic tissues and cells. Dev. Genet. 18:173-179.
33. Wright, W. E., and J. W. Shay. 1992. The two-stage mechanism controlling cellular senescence and immortalization. Exp. Gerontol. 27:383-389.
34. Wright, W. E., and J. W. Shay. 1992. Telomere positional effects and the regulation of cellular senescence. Trends Genet. 8:193-197.
35. Wright, W. E., J. W. Shay, and M. W. Piatyszek. 1995. Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity. Nucleic Acids Res. 23:3794-3795.
36. Zhong, Z., L. Shiue, S. Kaplan, and T. de Lange. 1992. A mammalian factor that binds telomeric TTAGGG repeats in vitro. Mol. Cell. Biol. 12:4834-4843.