Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABAA receptor α4 subunit expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 33, 2005, Pages 11894-11899

  Roberts, D S ^a   Raol, Y H ^b   Bandyopadhyay, S ^a   Lund, I V ^c   Budreck, E C ^b   Passini, M J ^c   Wolfe, J H ^c   Brooks Kayal, A R ^b,c   Russek, S J ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adeno associated virus; Dentate gyrus; Epilepsy; Immediate early genes

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA 4; EARLY GROWTH RESPONSE FACTOR 1; EARLY GROWTH RESPONSE FACTOR 3; PARVOVIRUS VECTOR; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; ZINC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DENTATE GYRUS; EMBRYO; EPILEPSY; EPILEPTIC STATE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GRANULE CELL; HIPPOCAMPUS; HUMAN; HUMAN CELL; HYPOTHESIS; MALE; NERVE CELL; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR UPREGULATION; REPORTER GENE; SEIZURE; SYNAPSE;

ANIMALS; BASE SEQUENCE; BRAIN; CELLS, CULTURED; DEPENDOVIRUS; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 3; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RNA, MESSENGER; SEIZURES; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION;

ADENO-ASSOCIATED VIRUS;

EID: 23844495064     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0501434102     Document Type: Article

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