Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release

Journal of Neurophysiology

Volumn 89, Issue 4, 2003, Pages 2021-2034

  Wu, Yuanming ^a   Wang, Wengang ^a   Richerson, George B ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID CARRIER; 4 AMINOBUTYRIC ACID RECEPTOR; BICUCULLINE; CALCIUM; CARRIER PROTEIN; SODIUM; TETANUS TOXIN; UNCLASSIFIED DRUG; VIGABATRIN;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL CELL; ARTICLE; FREQUENCY MODULATION; HIPPOCAMPUS; INHIBITORY POSTSYNAPTIC POTENTIAL; MINIATURE ENDPLATE POTENTIAL; NERVE CELL CULTURE; NERVE CELL INHIBITION; NERVE EXCITABILITY; NEUROTRANSMISSION; NEWBORN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; RECEPTOR DOWN REGULATION;

ANIMALS; ANTICONVULSANTS; CARRIER PROTEINS; CELLS, CULTURED; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; NEURAL INHIBITION; NEURONS; NIPECOTIC ACIDS; ORGANIC ANION TRANSPORTERS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA; SODIUM; SYNAPTIC VESICLES; TETANUS TOXIN; VIGABATRIN;

EID: 0037389053     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00856.2002     Document Type: Article

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