Absence of oncogenic transformation despite acquisition of cytogenetic aberrations in long-term cultured telomerase-immortalized human fetal hepatocytes

Cancer Letters

Volumn 256, Issue 1, 2007, Pages 120-127

  Haker, Björn ^a   Fuchs, Sigrid ^a   Dierlamm, Judith ^a   Brümmendorf, Tim H ^a   Wege, Henning ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

DNA damage response; Fetal human hepatocytes; Hepatocellular carcinoma; Malignant transformation; Telomerase immortalization; Trisomy 7

Indexed keywords

PROTEIN P53; TELOMERASE;

ANCHORAGE INDEPENDENT GROWTH; ANEUPLOIDY; ARTICLE; CELL IMMORTALIZATION; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; FEMALE; HUMAN; HUMAN CELL; KARYOTYPE 46,XX; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; MALIGNANT TRANSFORMATION; MONOSOMY X; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRISOMY 7;

BLOTTING, WESTERN; CELL AGING; CELL CYCLE; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CHROMOSOME ABERRATIONS; DNA DAMAGE; FETUS; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; KARYOTYPING; MUTATION; TELOMERASE; TELOMERE; TRANSDUCTION, GENETIC; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34548215056     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2007.06.007     Document Type: Article

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