Telomerase Alone Extends the Replicative Life Span of Human Skeletal Muscle Cells Without Compromising Genomic Stability

Human Gene Therapy

Volumn 14, Issue 15, 2003, Pages 1473-1487

  Wootton, Martha ^a   Steeghs, Karen ^b   Watt, Diana ^c   Munro, June ^b   Gordon, Katrina ^b   Ireland, Hazel ^b   Morrison, Vivienne ^b   Behan, Wilhelmina ^a   Parkinson, E Kenneth ^b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT ENZYME; TELOMERASE;

ARTICLE; CELL DIVISION; CELL REGENERATION; CELL TRANSFORMATION; CONTROLLED STUDY; DIPLOIDY; ENZYME ACTIVITY; ENZYME RECONSTITUTION; GENETIC STABILITY; HUMAN; HUMAN CELL; HUMAN GENOME; KARYOTYPE; LIFESPAN; MOUSE STRAIN; MUSCLE CELL; MUSCLE INJURY; NONVIRAL GENE THERAPY; ONCOGENE C MYC; PROTEIN EXPRESSION; PROTEIN METHYLATION; SKELETAL MUSCLE; WILD TYPE;

ADULT; ALLELES; BETA-GALACTOSIDASE; BLOTTING, WESTERN; BROMODEOXYURIDINE; CELL AGING; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; FEMALE; GENE THERAPY; GENOME; GENOTYPE; HELA CELLS; HETEROZYGOTE; HUMANS; IMMUNOHISTOCHEMISTRY; KARYOTYPING; MALE; MICROSATELLITE REPEATS; MUSCLE CELLS; MUSCLE, SKELETAL; MUSCLES; NECROSIS; NEOPLASM TRANSPLANTATION; REGENERATION; SEQUENCE ANALYSIS, DNA; SULFITES; TELOMERASE; TELOMERE; TIME FACTORS;

EID: 0142105972     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/104303403769211682     Document Type: Article

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