Cdk8 is essential for preimplantation mouse development

Molecular and Cellular Biology

Volumn 27, Issue 17, 2007, Pages 6177-6182

  Westerling, Thomas ^a   Kuuluvainen, Emilia ^a,b   Mäkelä, Tomi P ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 8;

ARTICLE; BLASTOMERE; CELL CULTURE; CELL FATE; CELL VIABILITY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME DEFICIENCY; ENZYME INACTIVATION; GENE INSERTION; GENE LOCUS; GENE REPRESSION; GENETIC TRANSCRIPTION; HETEROZYGOTE; HOMOZYGOSITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL;

ANIMALS; BLASTOCYST; CELL LINE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASES; GENOTYPE; HUMANS; MICE; MICE, KNOCKOUT; PHENOTYPE;

DANIO RERIO; MAMMALIA; METAZOA; MUS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 34548210859     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01302-06     Document Type: Article

References (54)

1. Bettencourt-Dias, M., R. Giet, R. Sinka, A. Mazumdar, W. G. Lock, F. Balloux, P. J. Zafiropoulos, S. Yamaguchi, S. Winter, R. W. Carthew, M. Cooper, D. Jones, L. Frenz, and D. M. Glover. 2004. Genome-wide survey of protein kinases required for cell cycle progression. Nature 432:980-987.
2. Bjorklund, M., M. Taipale, M. Varjosalo, J. Saharinen, J. Lahdenpera, and J. Taipale. 2006. Identification of pathways regulating cell size and cell-cycle progression by RNAi. Nature 439:1009-1013.
3. Bjorklund, S., and C. M. Gustafsson. 2005. The yeast Mediator complex and its regulation. Trends Biochem. Sci. 30:240-244.
4. Borggrefe, T., R. Davis, H. Erdjument-Bromage, P. Tempst, and R. D. Romberg. 2002. A complex of the Srb8, -9, -10, and -11 transcriptional regulatory proteins from yeast. J. Biol. Chem. 277:44202-44207.
5. Brummelkamp, T. R., R. Bernards, and R. Agami. 2002. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2:243-247.
6. Chadick, J. Z., and F. J. Asturias. 2005. Structure of eukaryotic Mediator complexes. Trends Biochem. Sci. 30:264-271.
7. Chi, Y., M. J. Huddleston, X. Zhang, R. A. Young, R. S. Annan, S. A. Carr, and R. J. Deshaies. 2001. Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. Genes Dev. 15:1078-1092.
8. Clemens, J. C., C. A. Worby, N. Simonson-Leff, M. Muda, T. Maehama, B. A. Hemmings, and J. E. Dixon. 2000. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc. Natl. Acad. Sci. USA 97:6499-6503.
9. Cutts, S. M., K. J. Fowler, B. T. Kile, L. L. Hii, R. A. O'Dowd, D. F. Hudson, R. Saffery, P. Kalitsis, E. Earle, and K. H. Choo. 1999. Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice. Hum. Mol. Genet. 8:1145-1155.
10. de Boer, J., I. Donker, J. de Wit, J. H. Hoeijmakers, and G. Weeda. 1998. Disruption of the mouse xeroderma pigmentosum group D DNA repair/basal transcription gene results in preimplantation lethality. Cancer Res. 58:89-94.
11. Eustice, D. C., P. A. Feldman, A. M. Colberg-Poley, R. M. Buckery, and R. H. Neubauer. 1991. A sensitive method for the detection of beta-galactosidase in transfected mammalian cells. BioTechniques 11:739-743.
12. Fryer, C. J., J. B. White, and K. A. Jones. 2004. Mastermind recruits CycC: CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol. Cell 16:509-520.
13. Fujimori, T., Y. Kurotaki, J. Miyazaki, and Y. Nabeshima. 2003. Analysis of cell lineage in two- and four-cell mouse embryos. Development 130:5113-5122.
14. Gardner, R. L. 2001. Specification of embryonic axes begins before cleavage in normal mouse development. Development 128:839-847.
15. Gustafsson, C. M., and T. Samuelsson. 2001. Mediator - a universal complex in transcriptional regulation. Mol. Microbiol. 41:1-8.
16. Hamatani, T., M. G. Carter, A. A. Sharov, and M. S. Ko. 2004. Dynamics of global gene expression changes during mouse preimplantation development. Dev. Cell 6:117-131.
17. Holstege, F. C., E. G. Jennings, J. J. Wyrick, T. I. Lee, C. J. Hengartner, M. R. Green, T. R. Golub, E. S. Lander, and R. A. Young. 1998. Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95:717-728.
18. Hong, S. K., C. E. Haldin, N. D. Lawson, B. M. Weinstein, I. B. Dawid, and N. A. Hukriede. 2005. The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney. Proc. Natl. Acad. Sci. USA 102:18473-18478.
19. Ito, M., H. J. Okano, R. B. Darnell, and R. G. Roeder. 2002. The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development. EMBO J. 21:3464-3475.
20. Ito, M., C. X. Yuan, H. J. Okano, R. B. Darnell, and R. G. Roeder. 2000. Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. Mol. Cell 5:683-693.
21. Jumaa, H., G. Wei, and P. J. Nielsen. 1999. Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20. Curr. Biol. 9:899-902.
22. Kiger, A. A., B. Baum, S. Jones, M. R. Jones, A. Coulson, C. Echeverri, and N. Perrimon. 2003. A functional genomic analysis of cell morphology using RNA interference. J. Biol. 2:27.
23. Kornberg, R. D. 2005. Mediator and the mechanism of transcriptional activation. Trends Biochem. Sci. 30:235-239.
24. Leclerc, V., J. P. Tassan, P. H. O'Farrell, E. A. Nigg, and P. Leopold. 1996. Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. Mol. Biol. Cell 7:505-513.
25. Lemaire, P., N. Garrett, and J. B. Gurdon. 1995. Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis. Cell 81:85-94.
26. Liao, S. M., J. Zhang, D. A. Jeffery, A. J. Koleske, C. M. Thompson, D. M. Chao, M. Viljoen, H. J. van Vuuren, and R. A. Young. 1995. A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature 374:193-196.
27. Lin, H. H., M. Khosla, H. J. Huang, D. W. Hsu, C. Michaelis, G. Weeks, and C. Pears. 2004. A homologue of Cdk8 is required for spore cell differentiation in Dictyostelium. Dev. Biol. 271:49-58.
28. Loncle, N., M. Boube, L. Joulia, C. Boschiero, M. Werner, D. L. Cribbs, and H. M. Bourbon. 2007. Distinct roles for Mediator Cdk8 module subunits in Drosophila development. EMBO J. 26:1045-1054.
29. MacGregor, G. R., and C. T. Caskey. 1989. Construction of plasmids that express E. coli beta-galactosidase in mammalian cells. Nucleic Acids Res. 17:2365.
30. MacKeigan, J. P., L. O. Murphy, and J. Blenis. 2005. Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat. Cell Biol. 7:591-600.
31. Nagy, A., M. Gertsenstein, K. Vintersten, and R. Behringer. 2003. Manipulating the mouse embryo, a laboratory manual, 3rd ed., vol. 1. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
32. Nelson, C., S. Goto, K. Lund, W. Hung, and I. Sadowski. 2003. Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12. Nature 421:187-190.
33. Pavri, R., B. Lewis, T. K. Kim, F. J. Dilworth, H. Erdjument-Bromage, P. Tempst, G. de Murcia, R. Evans, P. Chambon, and D. Reinberg. 2005. PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Mol. Cell 18:83-96.
34. Piotrowska, K., F. Wianny, R. A. Pedersen, and M. Zernicka-Goetz. 2001. Blastomeres arising from the first cleavage division have distinguishable fates in normal mouse development. Development 128:3739-3748.
35. Rau, M. J., S. Fischer, and C. J. Neumann. 2006. Zebrafish Trap230/Med12 is required as a coactivator for Sox9-dependent neural crest, cartilage and ear development. Dev. Biol. 296:83-93.
36. Sambrook, J., and D. W. Russell. 2001. Molecular cloning, a laboratory manual, 3rd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
37. Samuelsen, C. O., V. Baraznenok, O. Khorosjutina, H. Spahr, T. Kieselbach, S. Holmberg, and C. M. Gustafsson. 2003. TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution. Proc. Natl. Acad. Sci. USA 100:6422-6427.
38. Schlaeger, T. M., Y. Qin, Y. Fujiwara, J. Magram, and T. N. Sato. 1995. Vascular endothelial cell lineage-specific promoter in transgenic mice. Development 121:1089-1098.
39. Spahr, H., O. Khorosjutina, V. Baraznenok, T. Linder, C. O. Samuelsen, D. Hermand, T. P. Makela, S. Holmberg, and C. M. Gustafsson. 2003. Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro. J. Biol. Chem. 278:51301-51306.
40. Stryke, D., M. Kawamoto, C. C. Huang, S. J. Johns, L. A. King, C. A. Harper, E. C. Meng, R. E. Lee, A. Yee, L. L'Italien, P. T. Chuang, S. G. Young, W. C. Skarnes, P. C. Babbitt, and T. E. Ferrin. 2003. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 31:278-281.
41. Sun, X., Y. Zhang, H. Cho, P. Rickert, E. Lees, W. Lane, and D. Reinberg. 1998. NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription. Mol. Cell 2:213-222.
42. Taatjes, D. J., A. M. Naar, F. Andel III, E. Nogales, and R. Tjian. 2002. Structure, function, and activator-induced conformations of the CRSP coactivator. Science 295:1058-1062.
43. Takeda, K., T. Saito, and H. Ochiai. 2002. A novel Dictyostelium Cdk8 is required for aggregation, but is dispensable for growth. Dev. Growth Differ. 44:213-223.
44. Tassan, J. P., M. Jaquenoud, P. Leopold, S. J. Schultz, and E. A. Nigg. 1995. Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C. Proc. Natl. Acad. Sci. USA 92:8871-8875.
45. Thomas, M. C., and C. Chiang. 2006. The general transcription machinery and general cofactors. Crit. Rev. Biochem. Mol. Biol. 41:105-178.
46. Treisman, J. 2001. Drosophila homologues of the transcriptional coactivation complex subunits TRAP240 and TRAP230 are required for identical processes in eye-antennal disc development. Development 128:603-615.
47. Tsuzuki, T., Y. Fujii, K. Sakumi, Y. Tominaga, K. Nakao, M. Sekiguchi, A. Matsushiro, Y. Yoshimura, and T. Morita. 1996. Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc. Natl. Acad. Sci. USA 93:6236-6240.
48. Tudor, M., P. J. Murray, C. Onufryk, R. Jaenisch, and R. A. Young. 1999. Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice. Genes Dev. 13:2365-2368.
49. van de Peppel, J., N. Kettelarij, H. van Bakel, T. T. Kockelkorn, D. van Leenen, and F. C. Holstege. 2005. Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets. Mol. Cell 19:511-522.
50. Wang, Q. T., K. Piotrowska, M. A. Ciemerych, L. Milenkovic, M. P. Scott, R. W. Davis, and M. Zernicka-Goetz. 2004. A genome-wide study of gene activity reveals developmental signaling pathways in the preimplantation mouse embryo. Dev. Cell 6:133-144.
51. Wang, W., and X. Chen. 2004. HUA ENHANCER3 reveals a role for a cyclin-dependent protein kinase in the specification of floral organ identity in Arabidopsis. Development 131:3147-3156.
52. Watson, P., and J. Davey. 1998. Characterization of the Prk1 protein kinase from Zchizosaccharomyces pombe. Yeast 14:485-492.
53. Weber, R. J., and R. A. Pedersen, F. Wianny, M. J. Evans, and M. Zernicka-Goetz. 1999. Polarity of the mouse embryo is anticipated before implanatation. Development 126:5591-5598.
54. Yoda, A., H. Kouike, H. Okano, and H. Sawa. 2005. Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans. Development 132:1885-1893.