Suppression of type 1 diabetes in NOD mice by bifunctional peptide inhibitor: Modulation of the immunological synapse formation

Chemical Biology and Drug Design

Volumn 70, Issue 3, 2007, Pages 227-236

  Murray, Joseph S ^a   Oney, Sabah ^a   Page, Jennifer E ^a   Kratochvil Stava, Angela ^a   Hu, Yongbo ^a   Makagiansar, Irwan T ^a   Brown, John C ^a   Kobayashi, Naoki ^a   Siahaan, Teruna J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

APC; Diabetes; ICAM 1; Immunological synapse; LFA 1; MHC II; T cell

Indexed keywords

EPITOPE; GLUTAMATE DECARBOXYLASE 65; GLUTAMIC ACID DECARBOXYLASE BIFUNCTIONAL PEPTIDE INHIBITOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 4; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN INHIBITOR; T LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL INTERACTION; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DRUG BINDING; EFFECTOR CELL; FEMALE; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PRIORITY JOURNAL; SPLEEN CELL; TH2 CELL;

AMINO ACID SEQUENCE; ANIMALS; ANTIGEN-PRESENTING CELLS; DIABETES MELLITUS, TYPE 1; ENZYME INHIBITORS; FEMALE; GLUTAMATE DECARBOXYLASE; INTERCELLULAR ADHESION MOLECULE-1; MICE; MICE, INBRED NOD; MOLECULAR SEQUENCE DATA; PEPTIDES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

MUS;

EID: 34548180119     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2007.00552.x     Document Type: Article

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