Betaine-homocysteine methyltransferase: Zinc in a distorted barrel

Structure

Volumn 10, Issue 9, 2002, Pages 1159-1171

  Evans, John C ^a   Huddler, Donald P ^a   Jiracek, Jiri ^b   Castro, Carmen ^c   Millian, Norman S ^c   Garrow, Timothy A ^c   Ludwig, Martha L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

( )8 barrel; Homocysteine; Methyltransfer; Signature sequences; Thiolate ligands; Zinc

Indexed keywords

BETAINE; DISULFIDE; HOMOCYSTEINE; LIVER ENZYME; METHIONINE; METHYLTRANSFERASE; ZINC; BETAINE HOMOCYSTEINE METHYLTRANSFERASE; BHMT PROTEIN, HUMAN;

AMINO ACID SYNTHESIS; ARTICLE; BINDING SITE; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; METAL BINDING; MOLECULAR INTERACTION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REDUCTION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ELECTRICITY; ENZYME SPECIFICITY; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BETAINE-HOMOCYSTEINE S-METHYLTRANSFERASE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; HUMANS; METHYLTRANSFERASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; ZINC;

EID: 0036711477     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00796-7     Document Type: Article

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