H-Ras peptide and protein substrates bind protein farnesyltransferase as an ionized thiolate

Biochemistry

Volumn 37, Issue 44, 1998, Pages 15555-15562

  Hightower, Kendra E ^a   Huang, Chih Chin ^a   Casey, Patrick J ^a   Fierke, Carol A ^a,b  

^a DUKE UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; PROTEIN FARNESYLTRANSFERASE; SQUALENE SYNTHASE;

ALKYLATION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENZYME ACTIVITY; ENZYME SPECIFICITY; FLUORESCENCE; IONIZATION; NONHUMAN; ONCOGENE H RAS; PEPTIDE ANALYSIS; PH; PRIORITY JOURNAL; PROTEIN BINDING;

ALKYL AND ARYL TRANSFERASES; ANIMALS; BINDING, COMPETITIVE; COBALT; CYSTEINE; DANSYL COMPOUNDS; HYDROGEN-ION CONCENTRATION; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN ISOPRENYLATION; PROTO-ONCOGENE PROTEINS P21(RAS); RATS; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY; SULFHYDRYL COMPOUNDS; ZINC;

ANIMALIA;

EID: 0032480805     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981525v     Document Type: Article

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