Lanthionine-somatostatin analogs: Synthesis, characterization, biological activity, and enzymatic stability studies

Journal of Medicinal Chemistry

Volumn 40, Issue 14, 1997, Pages 2241-2251

  Ösapay, George ^a,b   Prokai, Laszlo ^c   Kim, Ho Seung ^c   Medzihradszky, Katalin F ^d   Coy, David H ^e   Liapakis, George ^f   Reisine, Terry ^f   Melacini, Giuseppe ^a   Zhu, Qin ^a   Wang, Susan H H ^a   Mattern, Ralph Heiko ^a   Goodman, Murray ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF FLORIDA HEALTH   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LANTHIONINE; OCTREOTIDE; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME STABILITY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

ALANINE; ANIMALS; BIOTRANSFORMATION; CELLS, CULTURED; DRUG DESIGN; GROWTH HORMONE; MALE; OCTREOTIDE; PEPTIDES, CYCLIC; PITUITARY GLAND, ANTERIOR; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SOMATOSTATIN; RECOMBINANT PROTEINS; SOMATOSTATIN; SPECTROMETRY, MASS, SECONDARY ION; STRUCTURE-ACTIVITY RELATIONSHIP; SULFIDES;

EID: 15644370832     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960850i     Document Type: Article

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