메뉴 건너뛰기




Volumn 3, Issue 4, 2007, Pages 477-489

Vitamin D receptor agonists as anti-inflammatory agents

Author keywords

[No Author keywords available]

Indexed keywords

1,25 DIHYDROXY 16 DIENE 26,27 HEXAFLUORO 19 NORCOLECALCIFEROL; 19 NOR 14,20 BISEPI 23 YNE ALFACALCIDOL; 20 EPICALCITRIOL; 22 ENE 25 OXA VITAMIN D; ALFACALCIDOL; ANTIINFLAMMATORY AGENT; BXL 219; BXL 628; CYCLOSPORIN A; ELOCALCITOL; GLUCOCORTICOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; LEXACALCITOL; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PLACEBO; RAPAMYCIN; SIMVASTATIN; TACROLIMUS; TX 527; UNCLASSIFIED DRUG; VITAMIN D; VITAMIN D DERIVATIVE; VITAMIN D RECEPTOR AGONIST; ZK 156979;

EID: 34447626100     PISSN: 1744666X     EISSN: None     Source Type: Journal    
DOI: 10.1586/1744666X.3.4.477     Document Type: Review
Times cited : (19)

References (99)
  • 1
    • 0035204814 scopus 로고    scopus 로고
    • Vitamin D: Its role and uses in immunology
    • Deluca HF, Cantorna MT. Vitamin D: its role and uses in immunology. Faseb J. 15, 2579-2585 (2001).
    • (2001) Faseb J , vol.15 , pp. 2579-2585
    • Deluca, H.F.1    Cantorna, M.T.2
  • 2
    • 0036220629 scopus 로고    scopus 로고
    • The coming of age of 1,25-dihydroxyvitamin D(3) analogs as immunomodulatory agents
    • Mathieu C, Adorini L. The coming of age of 1,25-dihydroxyvitamin D(3) analogs as immunomodulatory agents. Trends Mol Med. 8, 174-179. (2002).
    • (2002) Trends Mol Med , vol.8 , pp. 174-179
    • Mathieu, C.1    Adorini, L.2
  • 3
    • 0041864252 scopus 로고    scopus 로고
    • Vitamin D and its analogs as regulators of immune activation and antigen presentation
    • Griffin MD, Xing N, Kumar R. Vitamin D and its analogs as regulators of immune activation and antigen presentation. Annu. Rev. Nutr. 23, 117-145 (2003).
    • (2003) Annu. Rev. Nutr , vol.23 , pp. 117-145
    • Griffin, M.D.1    Xing, N.2    Kumar, R.3
  • 4
    • 0642367267 scopus 로고    scopus 로고
    • Current understanding of the function of the nuclear vitamin D receptor in response to its natural and synthetic ligands
    • Carlberg C. Current understanding of the function of the nuclear vitamin D receptor in response to its natural and synthetic ligands. Recent Results Cancer Res. 164, 29-42 (2003).
    • (2003) Recent Results Cancer Res , vol.164 , pp. 29-42
    • Carlberg, C.1
  • 5
    • 23044479095 scopus 로고    scopus 로고
    • Intervention in autoimmunity: The potential of vitamin D receptor agonists
    • Adorini L. Intervention in autoimmunity: the potential of vitamin D receptor agonists. Cell. Immunol. 233, 115-124 (2005).
    • (2005) Cell. Immunol , vol.233 , pp. 115-124
    • Adorini, L.1
  • 6
    • 27544437477 scopus 로고    scopus 로고
    • Multiple potential clinical benefits for 1α,25-dihydroxyvitamin D3 analogs in kidney transplant recipients
    • Griffin MD, Kumar R. Multiple potential clinical benefits for 1α,25-dihydroxyvitamin D3 analogs in kidney transplant recipients. J. Steroid Biochem. Mol. Biol. 97, 213-218 (2005).
    • (2005) J. Steroid Biochem. Mol. Biol , vol.97 , pp. 213-218
    • Griffin, M.D.1    Kumar, R.2
  • 7
    • 0034652314 scopus 로고    scopus 로고
    • Expression of 1,25-dihydroxyvitamin D(3) receptor in the immune system
    • Veldman CM, Cantorna MT, DeLuca HF. Expression of 1,25-dihydroxyvitamin D(3) receptor in the immune system. Arch. Biochem. Biophys. 374, 334-338 (2000).
    • (2000) Arch. Biochem. Biophys , vol.374 , pp. 334-338
    • Veldman, C.M.1    Cantorna, M.T.2    DeLuca, H.F.3
  • 8
    • 1242295281 scopus 로고    scopus 로고
    • Pharmacological induction of tolerogenic dendritic cells and regulatory T cells
    • Adorini L, Giarratana N, Penna G. Pharmacological induction of tolerogenic dendritic cells and regulatory T cells. Semin. Immunol. 16, 127-134 (2004).
    • (2004) Semin. Immunol , vol.16 , pp. 127-134
    • Adorini, L.1    Giarratana, N.2    Penna, G.3
  • 9
    • 33645224419 scopus 로고    scopus 로고
    • Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
    • Liu PT, Stenger S, Li H et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311, 1770-1773 (2006).
    • (2006) Science , vol.311 , pp. 1770-1773
    • Liu, P.T.1    Stenger, S.2    Li, H.3
  • 10
    • 4344665018 scopus 로고    scopus 로고
    • Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression
    • Wang TT, Nestel FP, Bourdeau V et al. Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J. Immunol. 173, 2909-2912 (2004).
    • (2004) J. Immunol , vol.173 , pp. 2909-2912
    • Wang, T.T.1    Nestel, F.P.2    Bourdeau, V.3
  • 11
    • 0025282010 scopus 로고
    • 1,25 (OH)"2D"3 production by T lymphocytes and alveolar macrophages recovered by lavage from normocalcemic patients with tuberculosis
    • Cadranel J, Garabedian M, Milleron B, Guillozo H, Akoun G, Hance AJ. 1,25 (OH)"2D"3 production by T lymphocytes and alveolar macrophages recovered by lavage from normocalcemic patients with tuberculosis. J. Clin. Invest. 85, 1588-1593 (1990).
    • (1990) J. Clin. Invest , vol.85 , pp. 1588-1593
    • Cadranel, J.1    Garabedian, M.2    Milleron, B.3    Guillozo, H.4    Akoun, G.5    Hance, A.J.6
  • 12
    • 33847220444 scopus 로고    scopus 로고
    • Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism
    • Schauber J, Dorsdiner RA, Coda AB et al. Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. J. Clin. Invest. 117, 803-811 (2007).
    • (2007) J. Clin. Invest , vol.117 , pp. 803-811
    • Schauber, J.1    Dorsdiner, R.A.2    Coda, A.B.3
  • 13
    • 34247890248 scopus 로고    scopus 로고
    • DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27
    • Sigmundsdottir H, Pan J, Debes GF et al. DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27. Nat. Immunol. 8, 285-293 (2007).
    • (2007) Nat. Immunol , vol.8 , pp. 285-293
    • Sigmundsdottir, H.1    Pan, J.2    Debes, G.F.3
  • 14
    • 33750934617 scopus 로고    scopus 로고
    • Dendritic cells: Translating innate to adaptive immunity
    • Steinman RM, Hemmi H. Dendritic cells: translating innate to adaptive immunity. Curr. Top. Microbiol. Immunol. 311, 17-18 (2006).
    • (2006) Curr. Top. Microbiol. Immunol , vol.311 , pp. 17-18
    • Steinman, R.M.1    Hemmi, H.2
  • 15
    • 17644372733 scopus 로고    scopus 로고
    • IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
    • Liu YJ. IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu. Rev. Immunol. 23, 275-306 (2005).
    • (2005) Annu. Rev. Immunol , vol.23 , pp. 275-306
    • Liu, Y.J.1
  • 16
    • 0345827684 scopus 로고    scopus 로고
    • Dendritic cells: Emerging pharmacological targets of immunosuppressive drugs
    • Hackstein H, Thomson AW. Dendritic cells: emerging pharmacological targets of immunosuppressive drugs. Nat. Rev. Immunol. 4, 24-34 (2004).
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 24-34
    • Hackstein, H.1    Thomson, A.W.2
  • 17
    • 3042550031 scopus 로고    scopus 로고
    • Dendritic cells as key targets for immunomodulation by vitamin D receptor ligands
    • Adorini L, Penna G, Giarratana N et al. Dendritic cells as key targets for immunomodulation by vitamin D receptor ligands. J. Steroid Biochem. Mol. Biol. 89-90, 437-441 (2004).
    • (2004) J. Steroid Biochem. Mol. Biol , vol.89-90 , pp. 437-441
    • Adorini, L.1    Penna, G.2    Giarratana, N.3
  • 18
    • 27744595600 scopus 로고    scopus 로고
    • + regulatory T cells by 1,25-dihydroxyvitamin D3
    • + regulatory T cells by 1,25-dihydroxyvitamin D3. Blood 106, 3490-3497 (2005).
    • (2005) Blood , vol.106 , pp. 3490-3497
    • Penna, G.1    Roncari, A.2    Amuchastegui, S.3
  • 19
    • 0037240852 scopus 로고    scopus 로고
    • Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10
    • Martin E, O'Sullivan B, Low P, Thomas R. Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10. Immunity 18, 155-167 (2003).
    • (2003) Immunity , vol.18 , pp. 155-167
    • Martin, E.1    O'Sullivan, B.2    Low, P.3    Thomas, R.4
  • 20
    • 0034603725 scopus 로고    scopus 로고
    • Mechanisms of gene regulation by vitamin D(3) receptor: A network of coactivator interactions
    • Rachez C, Freedman LP. Mechanisms of gene regulation by vitamin D(3) receptor: a network of coactivator interactions. Gene 246, 9-21 (2000).
    • (2000) Gene , vol.246 , pp. 9-21
    • Rachez, C.1    Freedman, L.P.2
  • 21
    • 0035881234 scopus 로고    scopus 로고
    • Regulatory T cells induced by 1α,25-dihydroxyvitamin D3 and mycophenotate mofetil treatment mediate transplantation tolerance
    • Gregod S, Casorati M, Amuchastegui S, Smiroldo S, Davalli AM, Adorini L. Regulatory T cells induced by 1α,25-dihydroxyvitamin D"3 and mycophenotate mofetil treatment mediate transplantation tolerance. J. Immunol. 167, 1945-1953 (2001).
    • (2001) J. Immunol , vol.167 , pp. 1945-1953
    • Gregod, S.1    Casorati, M.2    Amuchastegui, S.3    Smiroldo, S.4    Davalli, A.M.5    Adorini, L.6
  • 22
    • 0000026481 scopus 로고    scopus 로고
    • Dendritic cell modulation by 1α,25 dihydroxyvitamin D3 and its analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo
    • Griffin MD, Lutz W, Phan VA, Bachman LA, McKean DJ, Kumar R. Dendritic cell modulation by 1α,25 dihydroxyvitamin D3 and its analogs: a vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo. Proc. Natl. Acad. Sci. USA 22, 22 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.22 , pp. 22
    • Griffin, M.D.1    Lutz, W.2    Phan, V.A.3    Bachman, L.A.4    McKean, D.J.5    Kumar, R.6
  • 23
    • 0037302966 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases
    • Adorini L, Penna G, Giarratana N, Uskokovic M. Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases. J. Cell. Biochem. 88, 227-233 (2003).
    • (2003) J. Cell. Biochem , vol.88 , pp. 227-233
    • Adorini, L.1    Penna, G.2    Giarratana, N.3    Uskokovic, M.4
  • 24
    • 33845949937 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells
    • Penna G, Amuchastegui S, Giarratana N et al. 1,25-dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells. J. Immunol. 178, 145-153 (2007).
    • (2007) J. Immunol , vol.178 , pp. 145-153
    • Penna, G.1    Amuchastegui, S.2    Giarratana, N.3
  • 25
    • 23744437421 scopus 로고    scopus 로고
    • Noncalcemic actions of vitamin D receptor ligands
    • Nagpal S, Na S, Radinachalam R. Noncalcemic actions of vitamin D receptor ligands. Endocr. Rev. 26, 662-687 (2005).
    • (2005) Endocr. Rev , vol.26 , pp. 662-687
    • Nagpal, S.1    Na, S.2    Radinachalam, R.3
  • 27
    • 0043270561 scopus 로고    scopus 로고
    • The targets of vitamin D depend on the differentiation and activation status of CD4 positive T cells
    • Mahon BD, Wittke A, Weaver V, Cantorna. MT. The targets of vitamin D depend on the differentiation and activation status of CD4 positive T cells. J. Cell. Biochem. 89, 922-932 (2003).
    • (2003) J. Cell. Biochem , vol.89 , pp. 922-932
    • Mahon, B.D.1    Wittke, A.2    Weaver, V.3    Cantorna, M.T.4
  • 28
    • 0036314826 scopus 로고    scopus 로고
    • Immunomodulatory effects of vitamin D receptor ligands in autoimmune diseases
    • Adorini L. Immunomodulatory effects of vitamin D receptor ligands in autoimmune diseases. Int. Immunopharmacol. 2, 1017-1028. (2002).
    • (2002) Int. Immunopharmacol , vol.2 , pp. 1017-1028
    • Adorini, L.1
  • 29
    • 33845384182 scopus 로고    scopus 로고
    • Treatment of experimental autoimmune prostatitis in nonobese diabetic mice by the vitamin D receptor agonist elocalcitol
    • Penna G, Amuchastegui S, Cossetti C et al. Treatment of experimental autoimmune prostatitis in nonobese diabetic mice by the vitamin D receptor agonist elocalcitol. J. Immunol. 177, 8504-8511 (2006).
    • (2006) J. Immunol , vol.177 , pp. 8504-8511
    • Penna, G.1    Amuchastegui, S.2    Cossetti, C.3
  • 30
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of T(H) 17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
    • Steinman L. A brief history of T(H) 17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat. Med. 13, 139-145 (2007).
    • (2007) Nat. Med , vol.13 , pp. 139-145
    • Steinman, L.1
  • 31
    • 33750475959 scopus 로고    scopus 로고
    • Cross-talk between nuclear receptors and nuclear factor κB
    • De Bosscher K, Vanden Berghe W, Haegeman G. Cross-talk between nuclear receptors and nuclear factor κB. Oncogene 25, 6868-6886 (2006).
    • (2006) Oncogene , vol.25 , pp. 6868-6886
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3
  • 32
    • 0036781052 scopus 로고    scopus 로고
    • NF-κB regulation in the immune system
    • Li Q, Verma IM. NF-κB regulation in the immune system. Nat. Rev. Immunol. 2, 725-734 (2002).
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 33
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden MS, Ghosh S. Signaling to NF-κB. Genes Dev. 18, 2195-2224 (2004).
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 34
    • 1542676905 scopus 로고    scopus 로고
    • Direct transcriptional regulation of RelB by 1α,25-dihydroxyvitamin D3 and its analogs: Physiologic and therapeutic implications for dendritic cell function
    • Dong X, Craig T, Xing N et al. Direct transcriptional regulation of RelB by 1α,25-dihydroxyvitamin D3 and its analogs: physiologic and therapeutic implications for dendritic cell function. J. Biol. Chem. 278, 49378-49385 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 49378-49385
    • Dong, X.1    Craig, T.2    Xing, N.3
  • 35
    • 4043060025 scopus 로고    scopus 로고
    • A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and Type 1 diabetes development
    • Giarratana N, Penna G, Amuchastegui S, Mariani R, Daniel KC, Adorini L. A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and Type 1 diabetes development. J. Immunol. 173, 2280-2287 (2004).
    • (2004) J. Immunol , vol.173 , pp. 2280-2287
    • Giarratana, N.1    Penna, G.2    Amuchastegui, S.3    Mariani, R.4    Daniel, K.C.5    Adorini, L.6
  • 37
    • 33646228153 scopus 로고    scopus 로고
    • Inhibition of p38 by vitamin D reduces interleukin-6 production in normal prostate cells via mitogen-activated protein kinase phosphatase 5: Implications for prostate cancer prevention by vitamin D
    • Nonn L, Peng L, Feldman D, Peehl DM. Inhibition of p38 by vitamin D reduces interleukin-6 production in normal prostate cells via mitogen-activated protein kinase phosphatase 5: implications for prostate cancer prevention by vitamin D. Cancer Res. 66, 4516-4524 (2006).
    • (2006) Cancer Res , vol.66 , pp. 4516-4524
    • Nonn, L.1    Peng, L.2    Feldman, D.3    Peehl, D.M.4
  • 38
    • 33745839652 scopus 로고    scopus 로고
    • Increased NF-κB activity in fibroblasts lacking the vitamin D receptor
    • Sun J, Kong J, Duan Y et al. Increased NF-κB activity in fibroblasts lacking the vitamin D receptor. Am. J. Physiol. Endocrinol. Metab. 291, E315-E322 (2006).
    • (2006) Am. J. Physiol. Endocrinol. Metab , vol.291
    • Sun, J.1    Kong, J.2    Duan, Y.3
  • 39
    • 0038189866 scopus 로고    scopus 로고
    • Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells
    • Hewison M, Freeman L, Hughes SV et al. Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells. J. Immunol. 170, 5382-5390 (2003).
    • (2003) J. Immunol , vol.170 , pp. 5382-5390
    • Hewison, M.1    Freeman, L.2    Hughes, S.V.3
  • 40
    • 27644598539 scopus 로고    scopus 로고
    • Regulation of relB in dendritic cells by means of modulated association of vitamin D receptor and histone deacetylase 3 with the promoter
    • Dong X, Lutz W, Schroeder TM et al. Regulation of relB in dendritic cells by means of modulated association of vitamin D receptor and histone deacetylase 3 with the promoter. Proc. Natl. Acad. Sci. USA 102, 16007-16012 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 16007-16012
    • Dong, X.1    Lutz, W.2    Schroeder, T.M.3
  • 41
    • 0034161714 scopus 로고    scopus 로고
    • 1α,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
    • Penna G, Adorini L. 1α,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J. Immunol. 164, 2405-2411 (2000).
    • (2000) J. Immunol , vol.164 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 47
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 10, 942-949 (2004).
    • (2004) Nat. Med , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 49
    • 0037018104 scopus 로고    scopus 로고
    • +) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • +) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J. Exp. Med. 195, 603-616 (2002).
    • (2002) J. Exp. Med , vol.195 , pp. 603-616
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3
  • 50
    • 33744923159 scopus 로고    scopus 로고
    • Epidemiology of disease risks in relation to vitamin D insufficiency
    • Grant WB. Epidemiology of disease risks in relation to vitamin D insufficiency. Prog. Biophys. Mol. Biol. 92, 65-79 (2006).
    • (2006) Prog. Biophys. Mol. Biol , vol.92 , pp. 65-79
    • Grant, W.B.1
  • 51
    • 33644668623 scopus 로고    scopus 로고
    • High prevalence of vitamin D inadequacy and implications for health
    • Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin. Proc. 81, 353-373 (2006).
    • (2006) Mayo Clin. Proc , vol.81 , pp. 353-373
    • Holick, M.F.1
  • 52
    • 27544499686 scopus 로고    scopus 로고
    • Immunoregulation by 1,25-dihydroxyvitamin D3: Basic concepts
    • van Etten E, Mathieu C. Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J. Steroid Biochem. Mol. Biol. 97, 93-101 (2005).
    • (2005) J. Steroid Biochem. Mol. Biol , vol.97 , pp. 93-101
    • van Etten, E.1    Mathieu, C.2
  • 53
    • 33744826596 scopus 로고    scopus 로고
    • Vitamin D and its role in immunology: Multiple sclerosis, and inflammatory bowel disease
    • Cantorna MT. Vitamin D and its role in immunology: multiple sclerosis, and inflammatory bowel disease. Prog. Biophys. Mol. Biol. 92, 60-64 (2006).
    • (2006) Prog. Biophys. Mol. Biol , vol.92 , pp. 60-64
    • Cantorna, M.T.1
  • 54
    • 0036137987 scopus 로고    scopus 로고
    • Understanding autoimmune diabetes: Insights from mouse models
    • Adorini L, Gregori S, Harrison LC. Understanding autoimmune diabetes: insights from mouse models. Trends Mol. Med. 8, 31-38. (2002).
    • (2002) Trends Mol. Med , vol.8 , pp. 31-38
    • Adorini, L.1    Gregori, S.2    Harrison, L.C.3
  • 56
    • 33845720114 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis
    • Munger KL, Levin LI, Hollis BW, Howard NS, Ascherio A. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA 296, 2832-2838 (2006).
    • (2006) JAMA , vol.296 , pp. 2832-2838
    • Munger, K.L.1    Levin, L.I.2    Hollis, B.W.3    Howard, N.S.4    Ascherio, A.5
  • 57
    • 33745101112 scopus 로고    scopus 로고
    • The role ofvitamin D in multiple sclerosis
    • Brown SJ. The role ofvitamin D in multiple sclerosis. Ann. Pharmacother. 40, 1158-1161 (2006).
    • (2006) Ann. Pharmacother , vol.40 , pp. 1158-1161
    • Brown, S.J.1
  • 58
    • 33646339134 scopus 로고    scopus 로고
    • 1,25 dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNγ axis leading to Th1 response in experimental allergic encephalomyelitis
    • Muthian G, Raikwar HP, Rajasingh J, Bright JJ. 1,25 dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNγ axis leading to Th1 response in experimental allergic encephalomyelitis. J. Neurosci. Res. 83, 1299-1309 (2006).
    • (2006) J. Neurosci. Res , vol.83 , pp. 1299-1309
    • Muthian, G.1    Raikwar, H.P.2    Rajasingh, J.3    Bright, J.J.4
  • 59
    • 33750314525 scopus 로고    scopus 로고
    • IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis
    • Spach KM, Nashold FE, Dittel BN, Hayes CE. IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis. J. Immunol. 177, 6030-6037 (2006).
    • (2006) J. Immunol , vol.177 , pp. 6030-6037
    • Spach, K.M.1    Nashold, F.E.2    Dittel, B.N.3    Hayes, C.E.4
  • 60
    • 11444264875 scopus 로고    scopus 로고
    • The BsmI vitamin D receptor gene polymorphism is associated with ulcerative colitis in Jewish Ashkenazi patients
    • Dresner-Pollak R, Ackerman Z, Eliakim R, Karban A, Chowers Y, Fidder HH. The BsmI vitamin D receptor gene polymorphism is associated with ulcerative colitis in Jewish Ashkenazi patients. Genet. Test. 8, 417-420 (2004).
    • (2004) Genet. Test , vol.8 , pp. 417-420
    • Dresner-Pollak, R.1    Ackerman, Z.2    Eliakim, R.3    Karban, A.4    Chowers, Y.5    Fidder, H.H.6
  • 61
    • 33751584448 scopus 로고    scopus 로고
    • Report on the vitamin D status of adult and pediatric patients with inflammatory bowel disease and its significance for bone health and disease
    • Pappa HM, Grand RJ, Gordon CM. Report on the vitamin D status of adult and pediatric patients with inflammatory bowel disease and its significance for bone health and disease. Inflamm. Bowel Dis. 12, 1162-1174 (2006).
    • (2006) Inflamm. Bowel Dis , vol.12 , pp. 1162-1174
    • Pappa, H.M.1    Grand, R.J.2    Gordon, C.M.3
  • 62
    • 33846036986 scopus 로고    scopus 로고
    • IL-23: A master regulator in Crohn disease
    • Neurath MF. IL-23: a master regulator in Crohn disease. Nat. Med. 13, 26-28 (2007).
    • (2007) Nat. Med , vol.13 , pp. 26-28
    • Neurath, M.F.1
  • 63
    • 33645051954 scopus 로고    scopus 로고
    • Vitamin D receptor is required to control gastrointestinal immunity in IL-10 knockout mice
    • Froicu M, Zhu Y, Cantorna MT. Vitamin D receptor is required to control gastrointestinal immunity in IL-10 knockout mice. Immunology 117, 310-318 (2006).
    • (2006) Immunology , vol.117 , pp. 310-318
    • Froicu, M.1    Zhu, Y.2    Cantorna, M.T.3
  • 64
    • 34247282706 scopus 로고    scopus 로고
    • Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury
    • Froicu M, Cantorna MT. Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury. BMC Immunol. 8, 5 (2007).
    • (2007) BMC Immunol , vol.8 , pp. 5
    • Froicu, M.1    Cantorna, M.T.2
  • 65
    • 12344260581 scopus 로고    scopus 로고
    • Calcium and 1α,25-dihydroxyvitamin D3 target the TNF-α pathway to suppress experimental inflammatory bowel disease
    • Zhu Y, Mahon BD, Froicu M, Cantorna MT. Calcium and 1α,25-dihydroxyvitamin D3 target the TNF-α pathway to suppress experimental inflammatory bowel disease. Eur. J. Immunol. 35, 217-224 (2005).
    • (2005) Eur. J. Immunol , vol.35 , pp. 217-224
    • Zhu, Y.1    Mahon, B.D.2    Froicu, M.3    Cantorna, M.T.4
  • 66
    • 33751159861 scopus 로고    scopus 로고
    • The new low calcemic vitamin D analog 22-ene-25-oxa-vitamin D prominently ameliorates T helper cell type 1-mediated colitis in mice
    • Daniel C, Radeke HH, Sartory NA et al. The new low calcemic vitamin D analog 22-ene-25-oxa-vitamin D prominently ameliorates T helper cell type 1-mediated colitis in mice. J. Pharmacol. Exp. Ther. 319, 622-631 (2006).
    • (2006) J. Pharmacol. Exp. Ther , vol.319 , pp. 622-631
    • Daniel, C.1    Radeke, H.H.2    Sartory, N.A.3
  • 67
    • 33751400509 scopus 로고    scopus 로고
    • The Vitamin D analogue TX 527 blocks NF-κB activation in peripheral blood mononuclear cells of patients with Crohn's disease
    • Stio M, Martinesi M, Bruni S et al. The Vitamin D analogue TX 527 blocks NF-κB activation in peripheral blood mononuclear cells of patients with Crohn's disease. J. Steroid Biochem. Mol. Biol. 103, 51-60 (2007).
    • (2007) J. Steroid Biochem. Mol. Biol , vol.103 , pp. 51-60
    • Stio, M.1    Martinesi, M.2    Bruni, S.3
  • 69
    • 4143134325 scopus 로고    scopus 로고
    • Mechanisms in prostatitis/dironic pelvic pain syndrome
    • Pontari MA, Ruggieri MR. Mechanisms in prostatitis/dironic pelvic pain syndrome. J. Urol. 172, 839-845 (2004).
    • (2004) J. Urol , vol.172 , pp. 839-845
    • Pontari, M.A.1    Ruggieri, M.R.2
  • 70
    • 2342469355 scopus 로고    scopus 로고
    • Inhibition of prostate cell growth by BXL-628, a calcitriol analogue selected for a phase II clinical trial in patients with benign prostate hyperplasia
    • Crescioli C, Ferruzzi P, Caporali A et al. Inhibition of prostate cell growth by BXL-628, a calcitriol analogue selected for a phase II clinical trial in patients with benign prostate hyperplasia. Eur. J. Endocrinol. 150, 591-603 (2004).
    • (2004) Eur. J. Endocrinol , vol.150 , pp. 591-603
    • Crescioli, C.1    Ferruzzi, P.2    Caporali, A.3
  • 71
    • 29944444331 scopus 로고    scopus 로고
    • Could inflammation be a key component in the progression of benign prostatic hyperplasia?
    • Kramer G, Marberger M. Could inflammation be a key component in the progression of benign prostatic hyperplasia? Curr. Opin. Urol. 16, 25-29 (2006).
    • (2006) Curr. Opin. Urol , vol.16 , pp. 25-29
    • Kramer, G.1    Marberger, M.2
  • 72
    • 33646169337 scopus 로고    scopus 로고
    • Selective inhibitors of inducible nitric oxide synthase: Potential agents for the treatment of inflammatory diseases?
    • Tinker AC, Wallace AV. Selective inhibitors of inducible nitric oxide synthase: potential agents for the treatment of inflammatory diseases? Curr. Top. Med. Chem. 6, 77-92 (2006).
    • (2006) Curr. Top. Med. Chem , vol.6 , pp. 77-92
    • Tinker, A.C.1    Wallace, A.V.2
  • 73
    • 33947176624 scopus 로고    scopus 로고
    • Novel pathways that contribute to the anti-proliferative and chemopreventive activities of calcitriol in prostate cancer
    • Krishnan AV, Moreno J, Norm L et al. Novel pathways that contribute to the anti-proliferative and chemopreventive activities of calcitriol in prostate cancer. J Steroid Biochem. Mol. Biol. (2007).
    • (2007) J Steroid Biochem. Mol. Biol
    • Krishnan, A.V.1    Moreno, J.2    Norm, L.3
  • 74
    • 29044445300 scopus 로고    scopus 로고
    • BXCL628, a novel vitamin D3 analog arrests prostate growth in patients with benign prostatic hyperplasia: A randomized clinical trial
    • Colli E, Rigatti P, Montorsi F et al. BXCL628, a novel vitamin D3 analog arrests prostate growth in patients with benign prostatic hyperplasia: a randomized clinical trial. Eur. Urol. 49, 82-86 (2006).
    • (2006) Eur. Urol , vol.49 , pp. 82-86
    • Colli, E.1    Rigatti, P.2    Montorsi, F.3
  • 75
    • 0036782248 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 analogs as potential therapies in transplantation
    • Adorini L. 1,25-dihydroxyvitamin D3 analogs as potential therapies in transplantation. Curr. Opin. Investig. Drugs. 3, 1458-1463 (2002).
    • (2002) Curr. Opin. Investig. Drugs , vol.3 , pp. 1458-1463
    • Adorini, L.1
  • 77
    • 33749627353 scopus 로고    scopus 로고
    • Immunomodulation by 1,25-dihydroxyvitamin D3: Therapeutic implications in hemodialysis and renal transplantation
    • Mathieu C, Jafari M. Immunomodulation by 1,25-dihydroxyvitamin D3: therapeutic implications in hemodialysis and renal transplantation. Clin. Nephrol. 66, 275-283 (2006).
    • (2006) Clin. Nephrol , vol.66 , pp. 275-283
    • Mathieu, C.1    Jafari, M.2
  • 79
    • 18044400374 scopus 로고    scopus 로고
    • A combination of KH1060, a vitamin D(3) analogue, and cyclosporin prevents early graft failure and prolongs graft survival of xenogeneic islets in nonobese diabetic mice
    • Gysemans C, Waer M, Laureys J, Bouillon R, Mathieu C. A combination of KH1060, a vitamin D(3) analogue, and cyclosporin prevents early graft failure and prolongs graft survival of xenogeneic islets in nonobese diabetic mice. Transplant. Proc. 33, 2365. (2001).
    • (2001) Transplant. Proc , vol.33 , pp. 2365
    • Gysemans, C.1    Waer, M.2    Laureys, J.3    Bouillon, R.4    Mathieu, C.5
  • 81
    • 0042623568 scopus 로고    scopus 로고
    • Strong additive effect of 1,25-dihydroxycholecalciferol and cyclosporine A but not tacrolimus in rat lung allotransplantation
    • discussion 200
    • Stammberger U, Kubisa B, Gugger M et al. Strong additive effect of 1,25-dihydroxycholecalciferol and cyclosporine A but not tacrolimus in rat lung allotransplantation. Eur. J. Cardiothorac. Surg. 24, 196-200; discussion 200 (2003).
    • (2003) Eur. J. Cardiothorac. Surg , vol.24 , pp. 196-200
    • Stammberger, U.1    Kubisa, B.2    Gugger, M.3
  • 82
    • 33646005512 scopus 로고    scopus 로고
    • Vierboom M, Johnsson C, t Hart B, Jonker M. Monotherapy with the vitamin D analogue MC1288 does not result in prolonged kidney allograft survival in rhesus monkeys. Tanspl. Int. 19, 396-403 (2006).
    • Vierboom M, Johnsson C, t Hart B, Jonker M. Monotherapy with the vitamin D analogue MC1288 does not result in prolonged kidney allograft survival in rhesus monkeys. Tanspl. Int. 19, 396-403 (2006).
  • 83
    • 22144431544 scopus 로고    scopus 로고
    • Inhibition of acute and chronic allograft rejection in mouse models by BXL-628, a nonhypercalcemic vitamin D receptor agonist
    • Amuchastegui S, Daniel KC, Adorini L. Inhibition of acute and chronic allograft rejection in mouse models by BXL-628, a nonhypercalcemic vitamin D receptor agonist. Transplantation 80, 81-87 (2005).
    • (2005) Transplantation , vol.80 , pp. 81-87
    • Amuchastegui, S.1    Daniel, K.C.2    Adorini, L.3
  • 84
    • 24344440277 scopus 로고    scopus 로고
    • Prevention of chronic allograft rejection by Vitamin D receptor agonists
    • Adorini L, Amuchastegui S, Daniel KC. Prevention of chronic allograft rejection by Vitamin D receptor agonists. Immunol. Lett. 100, 34-41 (2005).
    • (2005) Immunol. Lett , vol.100 , pp. 34-41
    • Adorini, L.1    Amuchastegui, S.2    Daniel, K.C.3
  • 85
    • 33749252164 scopus 로고    scopus 로고
    • The vitamin D receptor as a therapeutic target
    • Campbell MJ, Adorini L. The vitamin D receptor as a therapeutic target. Expert Opin. Ther. Targets 10, 735-748 (2006).
    • (2006) Expert Opin. Ther. Targets , vol.10 , pp. 735-748
    • Campbell, M.J.1    Adorini, L.2
  • 87
    • 33645511267 scopus 로고    scopus 로고
    • Identification and characterization of noncalcemic, tissue-selective, nonsecosteroidal vitamin D receptor modulators
    • Ma Y, Khalifa B, Yee YK et al. Identification and characterization of noncalcemic, tissue-selective, nonsecosteroidal vitamin D receptor modulators. J. Clin. Invest. 116, 892-904 (2006).
    • (2006) J. Clin. Invest , vol.116 , pp. 892-904
    • Ma, Y.1    Khalifa, B.2    Yee, Y.K.3
  • 88
    • 0037302109 scopus 로고    scopus 로고
    • Evidence for tissue- and cell-type selective activation of the vitamin D receptor by Ro-26-9228, a noncalcemic analog of vitamin D3
    • Peleg S, Ismail A, Uskokovic MR, Avnur Z. Evidence for tissue- and cell-type selective activation of the vitamin D receptor by Ro-26-9228, a noncalcemic analog of vitamin D3. J. Cell. Biochem. 88, 267-273 (2003).
    • (2003) J. Cell. Biochem , vol.88 , pp. 267-273
    • Peleg, S.1    Ismail, A.2    Uskokovic, M.R.3    Avnur, Z.4
  • 89
    • 0036227148 scopus 로고    scopus 로고
    • Cellular and molecular events associated with the bone-protecting activity of the noncalcemic vitamin D analog Ro-26-9228 in osteopenic rats
    • Peleg S, Uskokovic M, Ahene A, Vickery B, Avnur Z. Cellular and molecular events associated with the bone-protecting activity of the noncalcemic vitamin D analog Ro-26-9228 in osteopenic rats. Endocrinology 143, 1625-1636 (2002).
    • (2002) Endocrinology , vol.143 , pp. 1625-1636
    • Peleg, S.1    Uskokovic, M.2    Ahene, A.3    Vickery, B.4    Avnur, Z.5
  • 90
    • 33947096931 scopus 로고    scopus 로고
    • Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol)
    • Adorini L, Penna G, Amuchastegui S et al. Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol). J. Steroid Biochem. Mol. Biol. 103, 689-693 (2007).
    • (2007) J. Steroid Biochem. Mol. Biol , vol.103 , pp. 689-693
    • Adorini, L.1    Penna, G.2    Amuchastegui, S.3
  • 91
    • 0030608964 scopus 로고    scopus 로고
    • 1α,25-dihydroxyvitamin D3 and a variety of its natural metabolites transcriptionally repress nudear-factor-κB-mediated interleukin-8 gene expression
    • Harant H, Andrew PJ, Reddy GS, Foglar E, Lindley IJ. 1α,25-dihydroxyvitamin D3 and a variety of its natural metabolites transcriptionally repress nudear-factor-κB-mediated interleukin-8 gene expression. Eur. J. Biochem. 250, 63-71 (1997).
    • (1997) Eur. J. Biochem , vol.250 , pp. 63-71
    • Harant, H.1    Andrew, P.J.2    Reddy, G.S.3    Foglar, E.4    Lindley, I.J.5
  • 92
    • 33751223544 scopus 로고    scopus 로고
    • Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
    • Mora JR, Iwata M, Eksteen B et al. Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells. Science 314, 1157-1160 (2006).
    • (2006) Science , vol.314 , pp. 1157-1160
    • Mora, J.R.1    Iwata, M.2    Eksteen, B.3
  • 93
    • 34247846432 scopus 로고    scopus 로고
    • Vitamins in control of lymphocyte migration
    • Mebius RE. Vitamins in control of lymphocyte migration. Nat. Immunol. 8, 229-230 (2007).
    • (2007) Nat. Immunol , vol.8 , pp. 229-230
    • Mebius, R.E.1
  • 94
    • 33645079892 scopus 로고    scopus 로고
    • An integrated biological approach to nuclear receptor signaling in physiological control and disease
    • Carlberg C, Dunlop TW. An integrated biological approach to nuclear receptor signaling in physiological control and disease. Crit. Rev. Eukaryot. Gene Expr. 16, 1-22 (2006).
    • (2006) Crit. Rev. Eukaryot. Gene Expr , vol.16 , pp. 1-22
    • Carlberg, C.1    Dunlop, T.W.2
  • 95
    • 31044447205 scopus 로고    scopus 로고
    • Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients
    • Xystrakis E, Kusumakar S, Boswell S et al. Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients. J. Clin. Invest. 116, 146-155 (2006).
    • (2006) J. Clin. Invest , vol.116 , pp. 146-155
    • Xystrakis, E.1    Kusumakar, S.2    Boswell, S.3
  • 96
    • 33745426510 scopus 로고    scopus 로고
    • Are statins analogues of vitamin D?
    • Grimes DS. Are statins analogues of vitamin D? Lancet 368, 83-86 (2006).
    • (2006) Lancet , vol.368 , pp. 83-86
    • Grimes, D.S.1
  • 97
    • 33646354412 scopus 로고    scopus 로고
    • Statin therapy and autoimmune disease: From protein prenylation to immunomodulation
    • Greenwood J, Steinman L, Zamvil SS. Statin therapy and autoimmune disease: from protein prenylation to immunomodulation. Nat. Rev. Immunol. 6, 358-370 (2006).
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 358-370
    • Greenwood, J.1    Steinman, L.2    Zamvil, S.S.3
  • 98
    • 2442561768 scopus 로고    scopus 로고
    • Oral simvastatin treatment in relapsing-remitting multiple sclerosis
    • Vollmer T, Key L, Durkalski V et al. Oral simvastatin treatment in relapsing-remitting multiple sclerosis. Lancet 363, 1607-1608 (2004).
    • (2004) Lancet , vol.363 , pp. 1607-1608
    • Vollmer, T.1    Key, L.2    Durkalski, V.3
  • 99
    • 30944452387 scopus 로고    scopus 로고
    • Vitamin D and its analogues: Do they protect against cardiovascular disease in patients with kidney disease?
    • Levin A, Li YC. Vitamin D and its analogues: do they protect against cardiovascular disease in patients with kidney disease? Kidney Int. 68, 1973-1981 (2005).
    • (2005) Kidney Int , vol.68 , pp. 1973-1981
    • Levin, A.1    Li, Y.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.