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Tchetgen M-BN, Oesterting JE. The effect of prostatitis, urinary retention, ejaculation and ambulation on the serum prostate specific antigen concentration. Urol Clin North Am 1997; 24:283-291. One PSA is often not enough as this review highlights potential influences.
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Klein LT, Lowe FC. The effects of prostatic manipulation on prostate-specific antigen levels. Urol Clin North Am 1997; 24:293-297. This emphasizes that it is important to know how much alteration can be caused iatrogenically.
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Richardson TD, Oesterling JE. Age-specific reference ranges for serum prostate-specific antigen. Urol Clin North Am 1997; 24:339-351. A review of age/race-referenced PSA by its initial proponent.
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Carter HB, Pearson JD. Prostate-specific antigen velocity and repeated measures of prostate-specific antigen. Ural Clin North Am 1997; 24:333-338. The significant cut-off levels are discussed along with important criteria for performing and interpreting PSA velocity.
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Abrahamsson PA, Lilja H, Oesterling JE. Molecular forms of serum prostate-specific antigen. Urol Clin North Am 1997; 24:353-365. The theory behind free PSA, the clinical studies and their limitations.
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Nixon RG, Brawer MK. Enhancing the specificity of prostate specific antigen: an overview of PSA density, velocity and age specific ranges. Br J Urol 1997; 79 (Suppl 1):61-67.
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Douglas, T.H.1
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Bangma Ch, Rietbergen JBW, Schroder FH. Prostate specific antigen as a screening test. The Netherlands experience. Urol Clin North Am 1997; 24:307-314. One of the few prospective screening trials aiming to address the question of whether we are reducing the mortality from prostate cancer.
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Bangma, Ch.1
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Bouffioux. Prostate cancer: to screen or not to screen? Eur Urol 1997; 31 (Suppl 1):2-4.
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Benoit RM, Naslund MJ. The socioeconomic implications of prostate specific antigen screening. Urol Clin North Am 1997; 24:451-458. This helps to give an insight into the imponderables of screening.
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Benoit, R.M.1
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Stenman U-H. Prostate specific antigen, clinical use and staging: an overview. Br J Urol 1997; 79 (Suppl 1):53-60.
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Arcangeli CG, Ornstein DK, Keetch DW, Andriole GL. Prostate-specific antigen as a screening test for prostate cancer. The United States experience. Urol Clin North Am 1997; 24:299-306. A comprehensive overview of the pertinent studies on low-level PSA and cancer risk.
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Partin AW, Kattan MW, Subong ENP, Walsh PC, Wojno KJ, Oesterling JE, Scardino PT, Pearson JD. Combination of prostate-specific antigen, clinical stage and Gleason score to predict pathological stage of localised prostate cancer. JAMA 1997; 277:1445-1451. This paper contains essential nomograms constructed from a multi-institutional database and formerly validated. By utilizing the variables of PSA, Gleason score and DRE, an accurate prediction of stage can be given to the patient. Fully informed consent and fully standardized treatment are thus available.
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JAMA
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Partin, A.W.1
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Bangma CH, Rietbergen JBW, Kranse R, Blijenberg BG, Petterson K, Schroder FH. The free to total prostate-specific antigen ratio improves the specificity of prostate specific antigen in screening for prostate cancer in the general population. J Urol 1997; 57:2191-2196. The latest update from the 'European Randomised Study of Screening for Prostate Cancer' prospective screening trials aiming to answer the question of whether or not we are reducing the mortality from prostate cancer.
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Catalona WJ, Smith DS, Ornstein DK. Prostate cancer detection in men with serum PSA concentrations of 2.6 ng/ml and benign prostate examination. Enhancement of specificity with free PSA measurements. JAMA 1997; 277:1452-1455. The latest update on Catalan's work in PSA screening. Should we be reassured if the PSA is less than 4 ng/ml? This would suggest not. This prospective study included almost 1000 patients, and cancer was detected in 22% - of which 19% were not organ-confined.
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JAMA
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Reissigl A, Bartsch G. Prostate specific antigen as a screening test. The Austrian experience. Urol Clin North Am 1997; 24:315-321. A revealing work on the trade-off between specificity and sensitivity.
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Carter, H.B.1
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Ukimura O, Durrani O, Babaian JR. Role of PSA and its indices in determining the need for repeat prostate biopsies. Urology 1997; 50:66-72.
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Perachino M, di Ciolo L, Barbetti V, Ardoino S, Vitali A, Introini C, Vigliercio G, Puppo P. Results of rebiopsy for suspected prostate carcinoma in symptomatic men with elevated PSA levels. Eur Urol 1997; 32:155-159.
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Catalona WJ, Beiser JA, Smith DS. Serum free prostate specific antigen and prostate specific antigen density measurements for predicting cancer in men with prior negative biopsies. J Urol 1997; 158:2162-2167. This helps to answer that most vexing of questions, who to put through the trauma of re-biopsy.
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J Urol
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Catalona, W.J.1
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Nixon RG, Wener MH, Smith KM, Parson RE, Strobel SA, Brawer MK. Biological variation of prostate specific antigen levels in serum: an elevation of day to day physiological fluctuations in a well defined cohort of 24 patients. J Urol 1997; 157:2183-2190. Indicates the worrying wide biological variation in PSA.
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Nixon, R.G.1
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Optenberg SA, Clark JY, Brawer MK, Thompson IM, Stein CR, Friedrichs P. Development of a decision-making tool to predict risk of prostate cancer: the cancer of the prostate risk index (CAPRI) test. Urology 1997; 50:665-671. Read this and try the computer-assisted decision tool software out.
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Urology
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Optenberg, S.A.1
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Rees MA, Resnick MI, Oesterling JE. Use of prostate specific antigen, Gleason score and digital rectal examination in staging patients with newly diagnosed prostate cancer. Urol Clin North Am 1997; 24:379-388. Research extrapolated into sound clinical advice.
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Urol Clin North Am
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Rees, M.A.1
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Using prostate-specific antigen to eliminate the staging radionuclide bone scan
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Lee CT, Oesterling JE. Using prostate-specific antigen to eliminate the staging radionuclide bone scan. Urol Clin North Am 1997; 24:389-394. Research extrapolated into sound clinical advice.
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Urol Clin North Am
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Thiel R, Pearson JD, Epstein JI, Walsh PC, Carter HB. Role of prostate specific antigen velocity in prediction of final pathologic stage in men with localised prostate cancer. Urology 1997; 49:716-720.
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Thiel, R.1
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Cookson MS, Fleshner NE, Soloway SM, Fair WR. Prognostic significance of prostate specific antigen in stage T1c prostate cancer treated by radical prostatectomy. Urology 1997; 49:887-893. This is further work to stress that T1c tumours are not insignificant. This study confirms the predictive power of PSA but also lowers the safe limit regarding organ-confined disease down to 7.0 ng/ml.
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Urology
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Cookson, M.S.1
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O'Dowd, GJ, Veltri RW, Orozco R, Miller MC, Oesterling JE. Update on the appropriate staging evaluation for newly diagnosed prostate cancer. J Urol 1997; 158:687-698. A well-written review of an area of much work.
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J Urol
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O'Dowd, G.J.1
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Reexamining the role of prostate-specific density in predicting outcome for clinically localised prostate cancer
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Ingenito AC, Ennis RD Hsu IC, Begg M, Benson MC, Schiff PB. Reexamining the role of prostate-specific density in predicting outcome for clinically localised prostate cancer. Urology 1997; 50:73-78.
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Urology
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The PSA nadir that indicates potential cure after radiotherapy for prostate cancer
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Critz FA, Levinson AK, Williams WH, Holladay DA, Holladay CT. The PSA nadir that indicates potential cure after radiotherapy for prostate cancer. Urology 1997; 49:322-326. A simple study with concise but clinically relevant conclusions. Speculates on whether, if you can predict failure by the PSA nadir, adjuvant therapy is appropriate.
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Urology
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Critz, F.A.1
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Urol Clin North Am
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