Bone mineral density, polyphenols and caffeine: A reassessment

Nutrition Research Reviews

Volumn 20, Issue 1, 2007, Pages 89-105

  Dew, T P ^a   Day, A J ^a   Morgan, M R A ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Bone health; Caffeine; Flavonoids; Polyphenols

Indexed keywords

ASCORBIC ACID; CAFFEINE; CALCITONIN; CALCITRIOL; CALCIUM; COUMESTROL; DAIDZEIN; FLAVONOID; FORMONONETIN; GENISTEIN; GLYCITEIN; HESPERIDIN; PARATHYROID HORMONE; PHYTOESTROGEN; PLACEBO; POLYPHENOL DERIVATIVE; VITAMIN D; ZERANOL;

ARTICLE; BEVERAGE; BONE DENSITY; BONE FRAGILITY; CALCIUM BALANCE; COFFEE; DISEASE ASSOCIATION; FRUIT; HUMAN; RISK FACTOR; SYSTEMATIC REVIEW; TEA; VEGETABLE;

EID: 34250864400     PISSN: 09544224     EISSN: 14752700     Source Type: Journal    
DOI: 10.1017/S0954422407738805     Document Type: Article

References (99)

1. Kanis JA, Brazier JE, Stevenson M, Calvert NW & Lloyd Jones M (2002) Treatment of Established Osteoporosis: a Systematic Review and Cost-Utility Analysis, Health Technology Assessment 6, no. 29. Southampton: National Coordinating Centre for Health Technology Assessment.
2. Torgerson DJ, Iglesias CP & Reid DM (2001) The economics of fracture prevention. In The Effective Management of Osteoporosis, pp. 111-122 [DH Barlow, RM Francis and A Miles, editors]. London: Aesculapius Medical Press.
3. Heaney RP & Recker RR (1982) Effects of nitrogen, phosphorus, and caffeine on calcium balance in women. J Lab Clin Med 99, 46-55.
4. Ganong WF (1979) Review of Medical Physiology, 9th ed. Stamford, CT, USA: Appleton and Lange.
5. Smith R (1993) Bone mineral. In Human Nutrition and Dietetics, 9th ed., pp. 163-173 [JS Garrow and WPT James, editors]. Edinburgh: Churchill Livingston.
6. Johnell OJ, Gullberg B, Kanis JA et al. (1995) Risk factors for hip fracture in European women: The MEDOS study. J Bone Miner Res 10, 1802-1815.
7. Weisburger JH (1997) Tea and health: a historical perspective. Cancer Lett 114, 315-317.
8. Hoover PA, Webber CE, Beaumont LF & Blake JM (1996) Post-menopausal bone mineral density: relationship to calcium intake, calcium absorption, residual oestrogen, body composition, and physical activity. Can J Physiol Pharmacol 74, 911-917.
9. Hegarty VM, May HM & Khaw K-T (2000) Tea drinking and bone mineral density in older women. Am J Clin Nutr 71, 1003-1007.
10. Crawley H (1990) Food Portion Sizes, 2nd ed. London: Her Majesty's Stationery Office.
11. Paul AA & Southgate DAT (1978) McCance, Widdowson's 'The Composition of Foods', 4th ed. London: Her Majesty's Stationery Office.
12. Wu C-H, Yang Y-C, Yao W-J, Lu F-H, Wu JS & Chang C-J (2002) Epidemiological evidence of increased bone mineral density in habitual tea drinkers. Arch Intern Med 162, 1001-1006.
13. Muraki S, Yamamoto S, Ishibashi H, Horiuchi T, Hosoi T, Suzuki T, Orimo H & Nakamura K (2003) Green tea drinking is associated with increased bone mineral density. J Bone Miner Res 18, Suppl. 2, S241.
14. Vestergaard P, Herman AP, Gram J et al. (2001) Evaluation of methods for prediction of bone mineral density by clinical and biochemical variables in perimenopausal women. Maturitas 40, 211-220.
15. Chen Z, Pettinger MB, Ritenbaugh C, LaCroix AZ, Robbins J, Caan BJ, Barad DH & Hakim IA (2003) Habitual tea consumption and risk of osteoporosis: a prospective study in the women's health initiative observational cohort. Am J Epidemiol 158, 772-781.
16. Chen Z, Pettinger MB, Hakim LA, LaCroix AZ, Robbins J, Caan BJ, Barad DH & Ritenbaugh C (2002) Does tea drinking affect bone density and risk of fractures among US post-menopausal women with different states of hormone replacement therapy? Results from the observational study in the women's health initiative. J Bone Miner Res 17, SA278.
17. Grynpas MD, Chachra D & Limeback H (2000) The action of fluoride on bone. In The Osteoporosis Primer, pp. 318-330 [JE Henderson and D Goltzman, editors]. Cambridge, UK: Cambridge University Press.
18. Whitford GM (1996) The Metabolism and Toxicity of Fluoride, 2nd ed. Basel and London: Karger.
19. Fung KF, Zhang ZQ, Wong JWC & Wong MH (1999) Fluoride contents in tea and soil from tea plantations and the release of fluoride into tea liquor during infusion. Environ Pollut 104, 197-205.
20. Duckworth SC & Duckworth R (1978) The ingestion of fluoride in tea. Br Dent J 145, 368-370.
21. Hallberg L, Sandström B & Agget PJ (1993) Iron, zinc and other trace elements. In Human Nutrition and Dietetics, 9th ed., pp. 174-207 [JS Garrow and WPT James, editors]. Edinburgh: Churchill Livingston.
22. Cao J, Zhao Y, Liu J, Xirao R, Danzeng S, Daji D & Yan Y (2003) Brick tea fluoride as a main source of adult fluorosis. Food Chem Toxicol 41, 535-542.
23. Zhang M, Shimmura T, Nishino H, Bi LF, Kajita E, Nagata M, Nagase H, Wang HB, Aratani T & Kagamimori S (2003) Influence of fluoride concentration in drinking water and brick-tea water on bone mass in healthy Inner Mongolian young women. Bone 32, S186.
24. Cao J, Zhao Y & Liu J (2001) Prevention of brick tea fluorosis in rats with low-fluoride brick tea on laboratory observation. Food Chem Toxicol 39, 615-619.
25. Whyte MP, Essmyer K, Gannon FH & Reinus WR (2005) Skeletal fluorosis and instant tea. Am J Med 118, 78-82.
26. Dufresne CJ & Farnworth ER (2001) A review of latest research findings on the health promotion properties of tea. J Nutr Biochem 12, 404-421.
27. Delaissé J-M, Eeckhout Y & Vaes G (1986) Inhibition of bone resorption in culture by (+)-catechin. Biochem Pharmacol 35, 3091-3094.
28. Park H, Ko S, Kim J & Kim S (2003) Effects of green tea extracts and polyphenols on the proliferation and activity of bone cells. J Bone Miner Res 18, Suppl. 2, S342.
29. Nakagawa H, Wachi M, Woo J-T, Kato M, Kasai S, Takahashi F, Lee I-S & Nagai K (2002) Fenton reaction is primarily involved in a mechanism of (-)-epigallocatechin-3-gallate to induce osteoclastic cell death. Biochem Biophys Res Comm 292, 94-101.
30. Choi E-M & Hwang J-K (2003) Effects of (+)-catechin on the function of osteoblastic cells. Biol Pharm Bull 26, 523-526.
31. Choi J-H, Rhee I-K, Park K-Y, Park K-Y, Kim J-K & Rhee SJ (2003) Action of green tea catechin on bone metabolic disorder in chronic cadmium-poisoned rats. Life Sci 73, 1479-1489.
32. Takita H, Kikuchi M, Sato Y & Kuboki Y (2002) Inhibition of BMP-induced ectopic bone formation by an antiangiogenic agent (epigallocatechin 3-gallate). Connect Tissue Res 43, 520-523.
33. Rassi CM, Lieberherr M, Chaumaz G, Pointillart A & Cournot G (2005) Modulation of osteoclastogenesis in porcine bone marrow cultures by quercetin and rutin. Cell Tissue Res 319, 383-393.
34. Wattel A, Kamel S, Mentaverri R, Lorget F, Prouilet C, Petit J-P, Fardelonne P & Brazier M (2003) Potent inhibitory effect of naturally occurring flavonoids quercetin and kaempferol on in vitro osteoclastic bone resorption. Biochem Pharmacol 65, 35-42.
35. Notoya M, Tsukamoto Y, Nishimura H, Woo J-T, Nagai K, Lee I-S & Hagiwara H (2004) Quercetin, a flavonoid, inhibits the proliferation, differentiation, and mineralization of osteoblasts in vitro. Eur J Pharmacol 485, 89-96.
36. Horcajada-Molteni M-N, Crespy V, Coxam V, Davicco M-J, Rémésy C & Barlet J-P (2000) Rutin inhibits ovarectomyinduced osteopenia in rats. J Bone Miner Res 15, 2251-2258.
37. Park YH, Han D-W, Suh H, Ryu GH, Hyon S-H, Cho BK & Park J-C (2003) Protective effects of green tea polyphenol against reactive oxygen species-induced oxidative stress in cultured rat calvarial osteoblast. Cell Biol Toxicol 19, 325-337.
38. Yano K, Heilbrun LK, Wasnich RD, Hankin JH & Vogel JM (1985) The relationship between diet and bone mineral content of multiple skeletal sites in elderly Japanese-American men and women living in Hawaii. Am J Clin Nutr 42, 877-888.
39. Kiel DP, Felson DT, Hannan MT, Anderson JJ & Wilson PW (1990) Caffeine and the risk of hip fracture: the Framingham study. Am J Epidemiol 132, 675-684.
40. Massey LK (1991) Perspectives caffeine and bone: directions for research. J Bone Miner Res 6, 1149-1151.
41. Nawrot P, Jordan S, Eastwood J, Rotstein J, Hugenholtz A & Feeley M (2003) Effects of caffeine on human health. Food Addit Contam 20, 1-30.
42. Johansson C, Mellström D, Lerner U & Österberg T (1992) Coffee drinking: a minor risk factor for bone loss and fractures. Age Ageing 21, 20-26.
43. Lloyd T, Rollings N, Eggli DF, Kieselhorst K & Chinchilli VM (1997) Dietary caffeine intake and bone status of postmenopausal women. Am J Clin Nutr 65, 1826-1830.
44. Conlisk AJ & Galuska DA (2000) Is caffeine associated with bone mineral density in young adult women? Prev Med 31, 562-568.
45. Cooper G, Atkinson EJ, Wahner HW, O'Fallon WM, Riggs BL, Judd HL & Melton LJ (1992) Is caffeine consumption a risk factor for osteoporosis? J Bone Miner Res 7, 465-471.
46. Rapuri PB, Gallagher JC, Kinyamu HK & Ryschon KL (2001) Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes. Am J Clin Nutr 74, 694-700.
47. Bergman EA, Sherrard DJ & Massey LK (1987) Effects of dietary caffeine on calcium-metabolism and bone turnover in adult women. Fed Proc 46, 632.
48. Harris S & Dawson-Hughes B (1994) Caffeine and bone loss in healthy post-menopausal women. J Bone Miner Res 8, S261.
49. Ilich JZ, Brownbill RA, Tamborini L & Crncevic-Orlic Z (2002) To drink or not to drink: how are alcohol, caffeine and past smoking related to bone mineral density in elderly women? J Am Coll Nutr 21, 536-544.
50. Glynn NW, Meilahn EN, Charron M, Anderson SJ, Kuller LH & Cauley JA (1995) Determinants of bone mineral density in older men. J Bone Miner Res 10, 1769-1777.
51. Hannan MT, Felson DT, Dawson-Hughes B, Tucker KL, Cupples LA, Wilson PWF & Kiel DP (2000) Risk factors for longitudinal bone loss in elderly men and women: The Framingham osteoporosis study. J Bone Miner Res 15, 710-720.
52. Rico H, Canal ML, Mañas P, Lavado JM, Costa C & Pedera JD (2002) Effects of caffeine, vitamin D, and other nutrients on quantitative phalangeal bone ultrasound in postmenopausal women. Nutrition 18, 189-193.
53. New SA, Bolton-Smith C, Grubb DA & Reid DM (1997) Nutritional influences on bone mineral density: a crosssectional study in premenopausal women. Am J Clin Nutr 65, 1831-1839.
54. Barger-Lux MJ & Heaney RP (1995) Caffeine and the calcium economy revisited. Osteoporos Int 5, 97-102.
55. Ferrini RL & Barrett-Connor E (1996) Caffeine intake and endogenous sex steroids levels in post-menopausal women: The Rancho Bernardo study. Am J Epidemiol 144, 642-644.
56. Heaney RP & Rafferty K (2001) Carbonated beverages and urinary calcium excretion. Am J Clin Nutr 74, 343-347.
57. Yeh JK & Aloia JF (1986) Differential effect of caffeine administration on calcium and vitamin D metabolism in young and adult rats. J Bone Miner Res 1, 251-258.
58. Chen X & Whitford GM (1999) Effects of caffeine on fluoride, calcium and phosphorus metabolism and calcified tissues in the rat. Arch Oral Biol 44, 33-39.
59. Sakamoto W, Nishihira J, Fujie K, Iizuka T, Handa H, Ozaki M & Yukawa S (2001) Effect of coffee consumption on bone metabolism. Bone 28, 332-336.
60. García-Contreras F, Paniagua R, Avila-Díaz M, Cabrera-Muñoz L, Martínez-Muñiz I, Foyo-Niembro E & Amato D (2000) Cola beverage consumption induces bone mineralisation reduction in ovariectomized rats. Arch Med Res 31, 360-365.
61. Heaney RP (2002) Effects of caffeine on bone and the calcium economy. Food Chem Toxicol 40, 1263-1270.
62. Massey LK (2001) Is caffeine a risk factor for bone loss in the elderly? Am J Clin Nutr 74, 569-570.
63. Steinmetz KA & Potter JD (1996) Vegetables, fruit and cancer prevention: a review. J Am Diet Assoc 96, 1027-1039.
64. Tylavsky FA, Holliday K, Danish R, Womack C, Norwood J & Carbone L (2004) Fruit and vegetable intakes are an independent predictor of bone size in early pubertal children. Am J Clin Nutr 79, 311-317.
65. Whiting SJ, Vatanparast H, Baxter-Jones A, Faulkner RA, Mirwald R & Bailey DA (2004) Factors that affect bone mineral accrual in the adolescent growth spurt. J Nutr 134, 696S-700S.
66. McGartland CP, Robson PJ, Murray LJ, Cran GW, Savage MJ, Watkins DC, Rooney MM & Boreham CA (2004) Fruit and vegetable consumption and bone mineral density: the Northern Ireland young hearts project. Am J Clin Nutr 80, 1019-1023.
67. Chen Y, Ho SC, Lee R, Lam S & Woo J (2001) Fruit intake is associated with better bone mass among Hong Kong Chinese early postmenopausal women. J Bone Miner Res 16, S386.
68. Tucker KL, Chen H, Hannan MT, Cupples LA, Wilson PWF, Felson D & Kiel DP (2002) Bone mineral density and dietary patterns in older adults: the Framingham osteoporosis study. Am J Clin Nutr 76, 245-252.
69. Tucker KL, Hannan MT, Chen H, Cupples LA, Wilson PWF & Kiel DP (1999) Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr 69, 727-736.
70. Kaptoge S, Welch A, McTaggart A, Mulligan A, Dalzell N, Day NE, Bingham S, Khaw K-T & Reeve J (2003) Effects of dietary nutrients and food groups on bone loss from the proximal femur in men and women in the 7th and 8th decades of age. Osteoporos Int 14, 418-428.
71. Macdonald HM, New SA, Golden MHN, Campbell MK & Reid DM (2004) Nutritional associations with bone loss during the menopausal transition: evidence of a beneficial effect of calcium, alcohol, and fruit and vegetable nutrients and of a detrimental effect of fatty acids. Am J Clin Nutr 79, 155-165.
72. New SA, Robins SP, Campbell MK, Martin JC, Garton MJ, Bolton-Smith C, Grubb DA, Lee SJ & Reid DM (2000) Dietary influences on bone mass and bone metabolism: further evidence of a positive link between fruit and vegetable consumption and bone health? Am J Clin Nutr 71, 142-151.
73. Tucker KL, Hannan MT & Kiel DP (2001) The acid-base hypothesis: diet and bone in the Framingham osteoporosis study. Eur J Nutr 40, 231-237.
74. New SA (2002) The role of the skeleton in acid-base homeostasis. Proc Nutr Soc 61, 151-164.
75. Mühlbauer RC, Lozano A & Reinli A (2002) Onion and a mixture of vegetables, salads, and herbs affect bone resorption in the rat by a mechanism independent of their base excess. J Bone Miner Res 17, 1230-1236.
76. Mühlbauer RC & Li F (1999) Effect of vegetables on bone metabolism. Nature 401, 343-344.
77. Mühlbauer RC, Lozano A, Reinli A & Wetli H (2003) Various selected vegetables, fruits, mushrooms and red wine residue inhibit bone resorption in rats. J Nutr 133, 3592-3597.
78. Arjmandi BH, Khalil DA, Lucas EA, Georgis A, Stoecker BJ, Hardin C, Payton ME & Wild RA (2002) Dried plums improve indices of bone formation in post-menopausal women. J Womens Health and Gend Based Med 11, 61-68.
79. Chiba H, Uehara M, Wu J, Wang X, Masuyama R, Suzuki K, Kanazawa K & Ishimi Y (2003) Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice. J Nutr 133, 1892-1897.
80. Setchell KDR & Lydeking-Olsen E (2003) Dietary phytooestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies. Am J Clin Nutr 78, 593S-609S.
81. Branca F (2003) Dietary phyto-oestrogens and bone health. Proc Nutr Soc 62, 877-887.
82. Draper CR, Edel MJ, Dick IM, Randall AG, Martin GB & Prince RL (1997) Phytoestrogens reduce bone loss and bone resorption in oophorectomized rats. J Nutr 127, 1795-1799.
83. Fanti P, Monier-Faugere MC, Geng Z, Schmidt J, Morris PE, Cohen D & Malluche HH (1998) The phytoestrogen genistein reduces bone loss in short-term ovariectomized rats. Osteoporos Int 8, 274-281.
84. Lee Y-B, Lee HJ, Kim KS, Le J-Y, Nam SY, Cheon S-H & Sohn H-S (2004) Evaluation of the preventative effect of isoflavone extract on bone loss in ovariectomized rats. Biosci Biotechnol Biochem 68, 1040-1045.
85. Deyhim F, Stoecker BJ, Brusewitz GH & Arjmandi BH (2003) The effects of estrogen depletion and isoflavones on bone metabolism in rats. Nutr Res 23, 123-130.
86. Atkinson C, Compston JE, Day NE, Dowsett M & Bingham SA (2004) The effects of phytoestrogen isoflavones on bone density in women: a double-blind, randomized, placebocontrolled trial. Am J Clin Nutr 79, 326-333.
87. Chen Y-M, Ho SC, Lam SSH, Ho SSS & Woo JLF (2003) Soy isoflavones have a favorable effect on bone loss in Chinese postmenopausal women with lower bone mass: a double-blind, randomized, controlled trial. J Clin Endocrinol Metab 88, 4740-4747.
88. Kreijkamp-Kaspers S, Kok L, Grobbee DE, de Haan EHF, Aleman A, Lampe JW & van der Schouw YT (2004) Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial. JAMA 292, 65-74.
89. Melis GB, Paoletti AM & Cagnacci A (1996) Ipriflavone prevents bone loss in post-menopausal women. Menopause 3, 27-32.
90. Maugeri D, Panebianco P, Russo MS et al. (1994) Ipriflavone-treatment of senile osteoporosis - results of a multicenter, double-blind clinical-trial of 2 years. Arch Gerontol Geriatr 19, 253-263.
91. Yamaguchi M (2002) Isoflavone and bone metabolism: its cellular mechanism and preventative role in bone loss. J Health Sci 48, 209-222.
92. Brouns F & Vermeer C (2000) Functional food ingredients for reducing the risks of osteoporosis. Trends Food Sci Technol 11, 22-33.
93. Wattanapenpaiboon N, Lukito W, Wahlqvist ML & Strauss BJG (2003) Dietary carotenoid intake as a predictor of bone mineral density. Asia Pac J Clin Nutr 12, 467-473.
94. Peterson J, Dwyer J, Bhagwat S, Haytowitz D, Holden J, Eldridge AL, Beecher G & Aladesanmi J (2005) Major flavonoids in dry tea. J Food Comp Anal 18, 487-501.
95. Astill C, Birch MR, Dacombe C, Humphrey PG & Martin PT (2001) Factors affecting the caffeine and polyphenol contents of black and green tea infusions. J Agric Food Chem 49, 5340-5347.
96. Clifford MN (1999) Chlorogenic acids and other cinnamates - nature, occurrence and dietary burden. J Sci Food Agric 79, 362-372.
97. Nebesny E & Budryn G (2003) Antioxidative activity of green and roasted coffee beans as influenced by convection and microwave roasting methods and content of certain compounds. Eur Food Res Technol 217, 157-163.
98. Debry G (1994) Coffee and Health. Paris: John Libbey Eurotext.
99. Pena A, Lino C & Silveira MIN (2005) Survey of caffeine levels in retail beverages in Portugal. Food Addit Contam 22, 91-96.