Amino acids determining enzyme-substrate specificity in prokaryotic and eukaryotic protein kinases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 8, 2003, Pages 4463-4468

  Li, Lewyn ^a,b   Shakhnovich, Eugene I ^a   Mirny, Leonid A ^b  

^a HARVARD UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE; PROTEIN KINASE; PROTEIN KINASE C;

ARTICLE; CELL FUNCTION; DATA ANALYSIS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME STRUCTURE; EUKARYOTE; HYPOTHESIS; MATHEMATICAL COMPUTING; MOLECULAR EVOLUTION; MUTATION; ORTHOLOGY; PARALOGY; PREDICTION; PRIORITY JOURNAL; PROKARYOTE; PROTEIN FAMILY; SEQUENCE HOMOLOGY; STATISTICAL ANALYSIS; THEORETICAL MODEL;

AMINO ACID SEQUENCE; AMINO ACIDS; BINDING SITES; ELECTROSTATICS; EUKARYOTIC CELLS; MODELS, MOLECULAR; MUTATION; PROKARYOTIC CELLS; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EUKARYOTA; PROKARYOTA;

EID: 0037447059     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0737647100     Document Type: Article

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