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Volumn 62, Issue 7, 2007, Pages 773-780

Antibody blocking of MHC II on human activated regulatory T cells abrogates their suppressive potential

Author keywords

Dendritic cells; MHC II; Regulatory T cells; Vaccination

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY CD28; MONOCLONAL ANTIBODY CD3;

EID: 34250682109     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2007.01339.x     Document Type: Article
Times cited : (11)

References (35)
  • 1
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressor T cells: More questions than answers
    • Shevach EM. CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol 2002 2 : 389 400.
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 2
    • 21744433238 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T lymphocytes in allergy and asthma
    • Shi H-Z, Qin X-J. CD4+CD25+ regulatory T lymphocytes in allergy and asthma. Allergy 2005 60 : 986 995.
    • (2005) Allergy , vol.60 , pp. 986-995
    • Shi, H.-Z.1    Qin, X.-J.2
  • 3
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004 22 : 531 562.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 4
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
    • Asano M, Toda M, Sakaguchi N, Sakaguchi S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med 1996 184 : 387 396.
    • (1996) J Exp Med , vol.184 , pp. 387-396
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3    Sakaguchi, S.4
  • 5
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998 188 : 287 296.
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 6
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi T, Kuniyasu Y, Toda M, Sakaguchi N, Itoh M, Iwata M et al. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 1998 10 : 1969 1980.
    • (1998) Int Immunol , vol.10 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3    Sakaguchi, N.4    Itoh, M.5    Iwata, M.6
  • 7
    • 0031739410 scopus 로고    scopus 로고
    • CD38+ CD45RB(low) CD4+ T cells: A population of T cells with immune regulatory activities in vitro
    • Read S, Mauze S, Asseman C, Bean A, Coffman R, Powrie F. CD38+ CD45RB(low) CD4+ T cells: a population of T cells with immune regulatory activities in vitro. Eur J Immunol 1998 28 : 3435 3447.
    • (1998) Eur J Immunol , vol.28 , pp. 3435-3447
    • Read, S.1    Mauze, S.2    Asseman, C.3    Bean, A.4    Coffman, R.5    Powrie, F.6
  • 8
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton AM, Shevach EM. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 2000 164 : 183 190.
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 9
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med 2001 193 : 1303 1310.
    • (2001) J Exp Med , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 10
    • 0035806290 scopus 로고    scopus 로고
    • Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
    • Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk AH. Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med 2001 193 : 1285 1294.
    • (2001) J Exp Med , vol.193 , pp. 1285-1294
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3    Tuettenberg, A.4    Knop, J.5    Enk, A.H.6
  • 11
    • 0035062581 scopus 로고    scopus 로고
    • Human anergic/suppressive CD4(+)CD25(+) T cells: A highly differentiated and apoptosis-prone population
    • Taams LS, Smith J, Rustin MH, Salmon M, Poulter LW, Akbar AN. Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population. Eur J Immunol 2001 31 : 1122 1131.
    • (2001) Eur J Immunol , vol.31 , pp. 1122-1131
    • Taams, L.S.1    Smith, J.2    Rustin, M.H.3    Salmon, M.4    Poulter, L.W.5    Akbar, A.N.6
  • 12
    • 0035054606 scopus 로고    scopus 로고
    • Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro
    • Stephens LA, Mottet C, Mason D, Powrie F. Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro. Eur J Immunol 2001 31 : 1247 1254.
    • (2001) Eur J Immunol , vol.31 , pp. 1247-1254
    • Stephens, L.A.1    Mottet, C.2    Mason, D.3    Powrie, F.4
  • 13
    • 0035525739 scopus 로고    scopus 로고
    • Human CD4(+)CD25(+) cells: A naturally occurring population of regulatory T cells
    • Ng WF, Duggan PJ, Ponchel F, Matarese G, Lombardi G, Edwards AD et al. Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells. Blood 2001 98 : 2736 2744.
    • (2001) Blood , vol.98 , pp. 2736-2744
    • Ng, W.F.1    Duggan, P.J.2    Ponchel, F.3    Matarese, G.4    Lombardi, G.5    Edwards, A.D.6
  • 16
    • 0037131969 scopus 로고    scopus 로고
    • Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells
    • Levings MK, Sangregorio R, Sartirana C, Moschin AL, Battaglia M, Orban PC et al. Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J Exp Med 2002 196 : 1335 1346.
    • (2002) J Exp Med , vol.196 , pp. 1335-1346
    • Levings, M.K.1    Sangregorio, R.2    Sartirana, C.3    Moschin, A.L.4    Battaglia, M.5    Orban, P.C.6
  • 17
    • 33645778289 scopus 로고    scopus 로고
    • MHC class II expression identifies functionally distinct human regulatory T cells
    • Baecher-Allan C, Wolf E, Hafler DA. MHC class II expression identifies functionally distinct human regulatory T cells. J Immunol 2006 176 : 4622 4631.
    • (2006) J Immunol , vol.176 , pp. 4622-4631
    • Baecher-Allan, C.1    Wolf, E.2    Hafler, D.A.3
  • 18
    • 0141678976 scopus 로고    scopus 로고
    • Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo
    • Jiang S, Camara N, Lombardi G, Lechler RI. Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo. Blood 2003 102 : 2180 2186.
    • (2003) Blood , vol.102 , pp. 2180-2186
    • Jiang, S.1    Camara, N.2    Lombardi, G.3    Lechler, R.I.4
  • 19
    • 0029918208 scopus 로고    scopus 로고
    • T cell suppression in transplantation tolerance through linked recognition
    • Davies JD, Leong LY, Mellor A, Cobbold SP, Waldmann H. T cell suppression in transplantation tolerance through linked recognition. J Immunol 1996 156 : 3602 3607.
    • (1996) J Immunol , vol.156 , pp. 3602-3607
    • Davies, J.D.1    Leong, L.Y.2    Mellor, A.3    Cobbold, S.P.4    Waldmann, H.5
  • 20
    • 0037093217 scopus 로고    scopus 로고
    • The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality
    • Taylor PA, Lees CJ, Blazar BR. The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood 2002 99 : 3493 3499.
    • (2002) Blood , vol.99 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 21
    • 0037025943 scopus 로고    scopus 로고
    • Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • Hoffmann P, Ermann J, Edinger M, Fathman CG, Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med 2002 196 : 389 399.
    • (2002) J Exp Med , vol.196 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 22
    • 0037026001 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T Cells: New therapeutics for graft-versus-host disease
    • Cohen JL, Trenado A, Vasey D, Klatzmann D, Salomon BL. CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease. J Exp Med 2002 196 : 401 406.
    • (2002) J Exp Med , vol.196 , pp. 401-406
    • Cohen, J.L.1    Trenado, A.2    Vasey, D.3    Klatzmann, D.4    Salomon, B.L.5
  • 24
    • 30744461834 scopus 로고    scopus 로고
    • Ex vivo-expanded CD4+CD25+ immunoregulatory T cells prevent graft-versus-host-disease by inhibiting activation/differentiation of pathogenic T cells
    • Trenado A, Sudres M, Tang Q, Maury S, Charlotte F, Gregoire S et al. Ex vivo-expanded CD4+CD25+ immunoregulatory T cells prevent graft-versus-host- disease by inhibiting activation/differentiation of pathogenic T cells. J Immunol 2006 176 : 1266 1273.
    • (2006) J Immunol , vol.176 , pp. 1266-1273
    • Trenado, A.1    Sudres, M.2    Tang, Q.3    Maury, S.4    Charlotte, F.5    Gregoire, S.6
  • 25
    • 2942733256 scopus 로고    scopus 로고
    • Human CD25+ regulatory T cells: Two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells
    • Stassen M, Fondel S, Bopp T, Richter C, Muller C, Kubach J et al. Human CD25+ regulatory T cells: two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells. Eur J Immunol 2004 34 : 1303 1311.
    • (2004) Eur J Immunol , vol.34 , pp. 1303-1311
    • Stassen, M.1    Fondel, S.2    Bopp, T.3    Richter, C.4    Muller, C.5    Kubach, J.6
  • 26
    • 23944501030 scopus 로고    scopus 로고
    • Regulatory activity of human CD4 CD25 T cells depends on allergen concentration, type of allergen and atopy status of the donor
    • Bellinghausen I, Konig B, Bottcher I, Knop J, Saloga J. Regulatory activity of human CD4 CD25 T cells depends on allergen concentration, type of allergen and atopy status of the donor. Immunology 2005 116 : 103 111.
    • (2005) Immunology , vol.116 , pp. 103-111
    • Bellinghausen, I.1    Konig, B.2    Bottcher, I.3    Knop, J.4    Saloga, J.5
  • 27
    • 20444503737 scopus 로고    scopus 로고
    • Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin
    • Smits HH, Engering A, van der Kleij D, de Jong EC, Schipper K, van Capel TM et al. Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J Allergy Clin Immunol 2005 115 : 1260 1267.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 1260-1267
    • Smits, H.H.1    Engering, A.2    Van Der Kleij, D.3    De Jong, E.C.4    Schipper, K.5    Van Capel, T.M.6
  • 28
    • 10844252294 scopus 로고    scopus 로고
    • Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells
    • Fehervari Z, Sakaguchi S. Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells. Int Immunol 2004 16 : 1769 1781.
    • (2004) Int Immunol , vol.16 , pp. 1769-1781
    • Fehervari, Z.1    Sakaguchi, S.2
  • 29
    • 23944469458 scopus 로고    scopus 로고
    • Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response
    • Schamel WW, Arechaga I, Risueno RM, van Santen HM, Cabezas P, Risco C et al. Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response. J Exp Med 2005 202 : 493 503.
    • (2005) J Exp Med , vol.202 , pp. 493-503
    • Schamel, W.W.1    Arechaga, I.2    Risueno, R.M.3    Van Santen, H.M.4    Cabezas, P.5    Risco, C.6
  • 30
    • 0035421654 scopus 로고    scopus 로고
    • Cutting edge: Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
    • Piccirillo CA, Shevach EM. Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J Immunol 2001 167 : 1137 1140.
    • (2001) J Immunol , vol.167 , pp. 1137-1140
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 31
    • 0021920334 scopus 로고
    • Dissection of human allostimulatory determinants with cloned T cells: Stimulation inhibition by monoclonal antibodies TU22, 34, 35, 36, 37, 39, 43, and 58 against distinct human MHC class II molecules
    • Pawelec G, Ziegler A, Wernet P. Dissection of human allostimulatory determinants with cloned T cells: stimulation inhibition by monoclonal antibodies TU22, 34, 35, 36, 37, 39, 43, and 58 against distinct human MHC class II molecules. Hum Immunol 1985 12 : 165 176.
    • (1985) Hum Immunol , vol.12 , pp. 165-176
    • Pawelec, G.1    Ziegler, A.2    Wernet, P.3
  • 32
    • 0030249953 scopus 로고    scopus 로고
    • MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span
    • Takeda S, Rodewald HR, Arakawa H, Bluethmann H, Shimizu T. MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span. Immunity 1996 5 : 217 228.
    • (1996) Immunity , vol.5 , pp. 217-228
    • Takeda, S.1    Rodewald, H.R.2    Arakawa, H.3    Bluethmann, H.4    Shimizu, T.5
  • 33
    • 0030775139 scopus 로고    scopus 로고
    • Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules
    • Kirberg J, Berns A, von Boehmer H. Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules. J Exp Med 1997 186 : 1269 1275.
    • (1997) J Exp Med , vol.186 , pp. 1269-1275
    • Kirberg, J.1    Berns, A.2    Von Boehmer, H.3
  • 34
    • 0030727150 scopus 로고    scopus 로고
    • Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells
    • Brocker T. Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells. J Exp Med 1997 186 : 1223 1232.
    • (1997) J Exp Med , vol.186 , pp. 1223-1232
    • Brocker, T.1
  • 35
    • 0034284220 scopus 로고    scopus 로고
    • Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes
    • Clarke SR, Rudensky AY. Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes. J Immunol 2000 165 : 2458 2464.
    • (2000) J Immunol , vol.165 , pp. 2458-2464
    • Clarke, S.R.1    Rudensky, A.Y.2


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