rasiRNAs, DNA damage, and embryonic axis specification

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 71, Issue , 2006, Pages 171-180

  Theurkauf, W E ^a   Klattenhoff, C ^a   Bratu, D P ^a   Mcginnis Schultz, N ^a   Koppetsch, B S ^a   Cook, H A ^b  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b WAGNER COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SMALL INTERFERING RNA; CHECKPOINT KINASE 2; HISTONE H2A; PROTEIN MEI 41; REPEAT ASSOCIATED SMALL INTERFERING RNA; RNA HELICASE; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; DNA DAMAGE; DROSOPHILA; FEMALE; GENE; GENETICS; METABOLISM; MICROTUBULE; MORPHOGENESIS; MUTATION; OOCYTE DEVELOPMENT; PRENATAL DEVELOPMENT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; AUBERGINE; DNA DAMAGE RESPONSE; DOUBLE STRANDED DNA BREAK; EMBRYO AXIS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE MUTATION; GERMLINE MUTATION; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RETROPOSON;

ANIMALS; BODY PATTERNING; DNA DAMAGE; DROSOPHILA; FEMALE; GENES, INSECT; MICROTUBULES; MODELS, BIOLOGICAL; MUTATION; OOGENESIS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 34250636790     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2006.71.066     Document Type: Conference Paper

References (62)

1. Abdu U., Brodsky M., and Schupbach T. 2002. Activation of a meiotic checkpoint during Drosophila oogenesis regulates the translation of Gurken through Chk2/Mnk. Curr. Biol. 12: 1645.
2. Abdu U., Gonzalez-Reyes A., Ghabrial A., and Schupbach T. 2003. The Drosophila spn-D gene encodes a RAD51C-like protein that is required exclusively during meiosis. Genetics 165: 197.
3. Aravin A., Gaidatzis D., Pfeffer S., Lagos-Quintana M., Landgraf P., Iovino N., Morris P., Brownstein M.J., Kuramochi-Miyagawa S., Nakano T., et al. 2006. A novel class of small RNAs bind to MILI protein in mouse testes. Nature 442: 203.
4. Aravin A.A., Klenov M.S., Vagin V.V., Bantignies F., Cavalli G., and Gvozdev V.A. 2004. Dissection of a natural RNA silencing process in the Drosophila melanogaster germ line. Mol. Cell. Biol. 24: 6742.
5. Aravin A.A., Naumova N.M., Tulin A.V., Vagin V.V., Rozovsky Y.M., and Gvozdev V.A. 2001. Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline. Curr. Biol. 11: 1017.
6. Bartek J. and Lukas J. 2003. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 3: 421.
7. Bartek J., Falck J., and Lukas J. 2001. CHK2 kinase - A busy messenger. Nat. Rev. Mol. Cell Biol. 2: 877.
8. Bernstein E., Kim S.Y., Carmell M.A., Murchison E.P., Alcorn H., Li M.Z., Mills A.A., Elledge S.J., Anderson K.V., and Hannon G.J. 2003. Dicer is essential for mouse development. Nat. Genet. 35: 215.
9. Bradshaw V.A. and McEntee K. 1989. DNA damage activates transcription and transposition of yeast Ty retrotransposons. Mol. Gen. Genet. 218: 465.
10. Casacuberta E. and Pardue M.L. 2005. HeT-A and TART, two Drosophila retrotransposons with a bona fide role in chromosome structure for more than 60 million years. Cytogenet. Genome Res. 110: 152.
11. Cook H., Koppetsch B., Wu J., and Theurkauf W. 2004. The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification. Cell 116:817.
12. Deng W. and Lin H. 2002. miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev. Cell 2: 819.
13. Deshpande G., Calhoun G., and Schedl P. 2005. Drosophila argonaute-2 is required early in embryogenesis for the assembly of centric/centromeric heterochromatin, nuclear division, nuclear migration, and germ-cell formation. Genes Dev. 19:1680.
14. Forstemann K., Tomari Y., Du T., Vagin V.V., Denli A.M., Bratu D.P., Klattenhoff C., Theurkauf W.E., and Zamore P.D. 2005. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNAbinding domain protein. PLoS Biol. 3: e236.
15. Fukagawa T., Nogami M., Yoshikawa M., Ikeno M., Okazaki T., Takami Y., Nakayama T., and Oshimura M. 2004. Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nat. Cell Biol. 6: 784.
16. Galiana-Arnoux D., Dostert C., Schneemann A., Hoffmann J.A., and Imler J.L. 2006. Essential function in vivo for Dicer-2 in host defense against RNA viruses in Drosophila. Nat. Immunol. 7: 590.
17. Ghabrial A. and Schupbach T. 1999. Activation of a meiotic checkpoint regulates translation of Gurken during Drosophila oogenesis. Nat. Cell Biol. 1: 354.
18. Ghabrial A., Ray R.P., and Schupbach T. 1998. okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis. Genes Dev. 12: 2711.
19. Giraldez A.J., Cinalli R.M., Glasner M.E., Enright A.J., Thomson J.M., Baskerville S., Hammond S.M., Bartel D.P., and Schier A.F. 2005. MicroRNAs regulate brain morphogenesis in zebrafish. Science 308: 833.
20. Girard A., Sachidanandam R., Hannon G.J., and Carmell M.A. 2006. A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 442: 199.
21. Gong W.J., McKim K.S., and Hawley R.S. 2005. All paired up with no place to go: Pairing, synapsis, and DSB formation in a balancer heterozygote. PLoS Genet. 1: e67.
22. Gonzalez-Reyes A., Elliott H., and St. Johnston D. 1995. Polarization of both major body axes in Drosophila by gurken-torpedo signalling. Nature 375: 654.
23. Grishok A., Pasquinelli A.E., Conte D., Li N., Parrish S., Ha I., Baillie D.L., Fire A., Ruvkun G., and Mello C.C. 2001. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106: 23.
24. Grivna S.T., Beyret E., Wang Z., and Lin H. 2006. A novel class of small RNAs in mouse spermatogenic cells. Genes Dev. 20:1709.
25. Gvozdev V.A., Aravin A.A., Abramov Y.A., Klenov M.S., Kogan G.L., Lavrov S.A., Naumova N.M., Olenkina O.M., Tulin A.V., and Vagin V.V. 2003. Stellate repeats: Targets of silencing and modules causing cis-inactivation and trans-activation. Genetica 117: 239.
26. Hannon G.J. 2002. RNA interference. Nature 418: 244.
27. Hatfield S.D., Shcherbata H.R., Fischer K.A., Nakahara K., Carthew R.W., and Ruohola-Baker H. 2005. Stem cell division is regulated by the microRNA pathway. Nature 435: 974.
28. Hirao A., Cheung A., Duncan G., Girard P.M., Elia A.J., Wakeham A., Okada H., Sarkissian T., Wong J.A., Sakai T., et al. 2002. Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol. Cell. Biol. 22: 6521.
29. Hutvagner G. and Zamore P.D. 2002. A microRNA in a multiple-turnover RNAi enzyme complex. Science 297: 2056.
30. Jang J.K., Sherizen D.E., Bhagat R., Manheim E.A., and McKim K.S. 2003. Relationship of DNA double-strand breaks to synapsis in Drosophila. J. Cell Sci. 116: 3069.
31. Kuramochi-Miyagawa S., Kimura T., Yomogida K., Kuroiwa A., Tadokoro Y., Fujita Y., Sato M., Matsuda Y., and Nakano T. 2001. Two mouse piwi-related genes: miwi and mili. Mech. Dev. 108: 121.
32. Lee Y.S., Nakahara K., Pham J.W., Kim K., He Z., Sontheimer E.J., and Carthew R.W. 2004. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117: 69.
33. Madigan J.P., Chotkowski H.L., and Glaser R.L. 2002. DNA double-strand break-induced phosphorylation of Drosophila histone variant H2Av helps prevent radiation-induced apoptosis. Nucleic Acids Res. 30: 3698.
34. McKim K.S. and Hayashi-Hagihara A. 1998. mei-W68 in Drosophila melanogaster encodes a Spo11 homolog: Evidence that the mechanism for initiating meiotic recombination is conserved. Genes Dev. 12: 2932.
35. Modesti M. and Kanaar R. 2001. DNA repair: Spot(light)s on chromatin. Curr. Biol. 11: R229.
36. Morris J. and Lehmann R. 1999. Drosophila oogenesis: Versatile spn doctors. Curr. Biol. 9: R55.
37. Neuman-Silberberg F.S. and Schupbach T. 1993. The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF alpha-like protein. Cell 75: 165.
38. Oikemus S.R., McGinnis N., Queiroz-Machado J., Tukachinsky H., Takada S., Sunkel C.E., and Brodsky M.H. 2004. Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect. Genes Dev. 18: 1850.
39. Okamura K., Ishizuka A., Siomi H., and Siomi M.C. 2004. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev. 18: 1655.
40. Pal-Bhadra M., Leibovitch B.A., Gandhi S.G., Rao M., Bhadra U., Birchler J.A., and Elgin S.C. 2004. Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science 303: 669.
41. Pardue M.L., Rashkova S., Casacuberta E., DeBaryshe P.G., George J.A., and Traverse K.L. 2005. Two retrotransposons maintain telomeres in Drosophila. Chromosome Res. 13: 443.
42. Provost P., Silverstein R.A., Dishart D., Walfridsson J., Djupedal I., Kniola B., Wright A., Samuelsson B., Radmark O., and Ekwall K. 2002. Dicer is required for chromosome segregation and gene silencing in fission yeast cells. Proc. Natl. Acad. Sci. 99: 16648.
43. Redon C., Pilch D., Rogakou E., Sedelnikova O., Newrock K., and Bonner W. 2002. Histone H2A variants H2AX and H2AZ. Curr. Opin. Genet. Dev. 12: 162.
44. Riechmann V. and Ephrussi A. 2001. Axis formation during Drosophila oogenesis. Curr. Opin. Genet. Dev. 11: 374.
45. Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., and Bonner W.M. 1998. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273: 5858.
46. Roth S., Neuman-Silberberg F.S., Barcelo G., and Schupbach T. 1995. cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila. Cell 81: 967.
47. Sacerdot C., Mercier G., Todeschini A.L., Dutreix M., Springer M., and Lesage P. 2005. Impact of ionizing radiation on the life cycle of Saccharomyces cerevisiae Ty1 retrotransposon. Yeast 22: 441.
48. Scholes D.T., Kenny A.E., Gamache E.R., Mou Z., and Curcio M.J. 2003. Activation of a LTR-retrotransposon by telomere erosion. Proc. Natl. Acad. Sci. 100: 15736.
49. Schupbach T. 1987. Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogaster. Cell 49: 699.
50. Spradling A.C. 1993. Germline cysts: Communes that work. Cell 72: 649.
51. Stapleton W., Das S., and McKee B.D. 2001. A role of the Drosophila homeless gene in repression of Stellate in male meiosis. Chromosoma 110: 228.
52. Styhler S., Nakamura A., Swan A., Suter B., and Lasko P. 1998. vasa is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development. Development 125: 1569.
53. Takada S., Kelkar A., and Theurkauf W.E. 2003. Drosophila checkpoint kinase 2 couples centrosome function and spindle assembly to genomic integrity. Cell 113: 87.
54. Theurkauf W.E., Alberts B.M., Jan Y.N., and Jongens T.A. 1993. A central role for microtubules in the differentiation of Drosophila oocytes. Development 118: 1169.
55. Theurkauf W.E., Smiley S., Wong M.L., and Alberts B.M. 1992. Reorganization of the cytoskeleton during Drosophila oogenesis: Implications for axis specification and intercellular transport. Development 115: 923.
56. Tomari Y., Matranga C., Haley B., Martinez N., and Zamore P.D. 2004a. A protein sensor for siRNA asymmetry. Science 306: 1377.
57. Tomari Y., Du T., Haley B., Schwarz D., Bennett R., Cook H., Koppetsch B., Theurkauf W., and Zamore P.D. 2004b. RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 116: 831.
58. Vagin V.V., Klenov M.S., Kalmykova A., Stolyarenko A.D., Kotelnikov R.N., and Gvozdev V. 2004. The RNA interference proteins and vasa locus are involved in the silencing of retrotransposons in the female germline of Drososophla melanogaster. RNA Biol. 1: 54.
59. Vagin V.V., Sigova A., Li C., Seitz H., Gvozdev V., and Zamore P.D. 2006. A distinct small RNA pathway silences selfish genetic elements in the germline. Science 313: 320.
60. Volpe T., Schramke V., Hamilton G.L., White S.A., Teng G., Martienssen R.A., and Allshire R.C. 2003. RNA interference is required for normal centromere function in fission yeast. Chromosome Res. 11: 137.
61. Wang X.H., Aliyari R., Li W.X., Li H.W., Kim K., Carthew R., Atkinson P., and Ding S.W. 2006. RNA interference directs innate immunity against viruses in adult Drosophila. Science 312: 452.
62. Wassenegger M. 2005. The role of the RNAi machinery in heterochromatin formation. Cell 122: 13.