Cytosine deaminase/5-fluorocytosine gene therapy and Apo2L/TRAIL cooperate to kill TRAIL-resistant tumor cells

Cancer Gene Therapy

Volumn 14, Issue 7, 2007, Pages 640-651

  Wei, J ^a   Wahl, J ^a   Knauss, H ^a   Zeller, S ^a   Jarmy, G ^a,c   Fitze, G ^b   Debatin, K M ^a   Beltinger, C ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Apo2L TRAIL; Cytosine deaminase 5 fluorocytosine; XIAP

Indexed keywords

APO2 LIGAND TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; CASPASE 3; CYTOSINE DEAMINASE; CYTOSINE DEAMINASE FLUCYTOSINE; FLUCYTOSINE; RECOMBINANT DNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; MOUSE; NEUROBLASTOMA; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; TUMOR GROWTH; TUMOR RESISTANCE;

ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CASPASES; CELL DIVISION; CELL LINE, TUMOR; CLONING, MOLECULAR; CYTOSINE DEAMINASE; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FEMALE; FLUCYTOSINE; GENE THERAPY; HUMANS; MICE; MICE, KNOCKOUT; NEUROBLASTOMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

MUS;

EID: 34250366089     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/sj.cgt.7701051     Document Type: Article

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