Rac1 function is required for Src-induced transformation: Evidence of a role for Tiam1 and Vav2 in Rac activation by Src

Journal of Biological Chemistry

Volumn 278, Issue 36, 2003, Pages 34339-34346

  Servitja, Joan Marc ^a,c   Marinissen, Maria Julia ^a   Sodhi, Akrit ^a   Bustelo, Xosé R ^b   Gutkind, J Silvio ^a,d  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF SALAMANCA   (Spain)

^c HOSPITAL CLÍNIC   (Spain)

^d NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CHEMICAL ACTIVATION; ENZYME INHIBITION; ONCOLOGY; TUMORS;

CELL TRANSFORMATIONS;

HUMAN ENGINEERING;

ADAPTOR PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN; PROTEIN TIAM1; PROTEIN VAV2; RAC1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TYROSINE; UNCLASSIFIED DRUG; 2,3 DIHYDRO 2 OXO 3 (4,5,6,7 TETRAHYDRO 1H INDOL 2 YLMETHYLENE) 1H INDOLE 5 SULFONIC ACID DIMETHYLAMIDE; DNA; ENZYME INHIBITOR; GUANOSINE TRIPHOSPHATASE; INDOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; ONCOPROTEIN; PERVANADATE; PROTEIN C JUN; PROTEIN KINASE P60; SULFONAMIDE; TIAM1 PROTEIN, HUMAN; TIAM1 PROTEIN, MOUSE; VANADIC ACID; VAV PROTEIN; VAV2 PROTEIN, HUMAN; VAV2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL TRANSFORMATION; EFFECTOR CELL; ENZYME ACTIVATION; GENE MUTATION; MALIGNANT TRANSFORMATION; MOLECULAR CLONING; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ALLELE; ANIMAL; CATALYSIS; CELL LINE; CELL STRAIN 3T3; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HUMAN; METABOLISM; MOUSE; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; PLASMID; PROMOTER REGION; REPORTER GENE; TIME;

ANIMALIA;

3T3 CELLS; ALLELES; ANIMALS; BINDING SITES; CATALYSIS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; DNA; ENZYME ACTIVATION; ENZYME INHIBITORS; GENES, REPORTER; GTP PHOSPHOHYDROLASES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; INDOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 4; MICE; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; ONCOGENE PROTEINS; PHOSPHORYLATION; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEINS; PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS C-VAV; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RAC1 GTP-BINDING PROTEIN; SULFONAMIDES; TIME FACTORS; TRANSFECTION; TYROSINE; VANADATES;

EID: 0141668894     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302960200     Document Type: Article

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