-
1
-
-
0032763469
-
Specificity, diversity and regulation in TGF-beta superfamily signalling
-
Piek E., Heldin C.H., and Ten Dijke P. Specificity, diversity and regulation in TGF-beta superfamily signalling. FASEB J 13 (1999) 2105-2124
-
(1999)
FASEB J
, vol.13
, pp. 2105-2124
-
-
Piek, E.1
Heldin, C.H.2
Ten Dijke, P.3
-
2
-
-
33746829275
-
Transforming growth factor-betas and vascular disorders
-
Bobik A. Transforming growth factor-betas and vascular disorders. Arterioscler Thromb Vasc Biol 26 (2006) 1712-1720
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1712-1720
-
-
Bobik, A.1
-
3
-
-
0037114003
-
Matrix metalloproteinase- dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosis
-
Karsdal M.A., Larsen L., Engsig M.T., Lou H., Ferreras M., Lochter A., Delaisse J.M., and Foged N.T. Matrix metalloproteinase- dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosis. J Biol Chem 277 (2002) 44061-44067
-
(2002)
J Biol Chem
, vol.277
, pp. 44061-44067
-
-
Karsdal, M.A.1
Larsen, L.2
Engsig, M.T.3
Lou, H.4
Ferreras, M.5
Lochter, A.6
Delaisse, J.M.7
Foged, N.T.8
-
4
-
-
0035914339
-
Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3
-
Yuan W., and Varga J. Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3. J Biol Chem 276 (2001) 38502-38510
-
(2001)
J Biol Chem
, vol.276
, pp. 38502-38510
-
-
Yuan, W.1
Varga, J.2
-
5
-
-
9444228224
-
Structurally different RGTAs modulate collagen-type expression by cultured aortic smooth muscle cells via different pathways involving fibroblast growth factor-2 or transforming growth factor-beta1
-
Alexakis C., Mestries P., Garcia S., Petit E., Barbier V., Papy-Garcia D., Sagot M.A., Barritault D., Caruelle J.P., and Kern P. Structurally different RGTAs modulate collagen-type expression by cultured aortic smooth muscle cells via different pathways involving fibroblast growth factor-2 or transforming growth factor-beta1. FASEB J 18 (2005) 1147-1149
-
(2005)
FASEB J
, vol.18
, pp. 1147-1149
-
-
Alexakis, C.1
Mestries, P.2
Garcia, S.3
Petit, E.4
Barbier, V.5
Papy-Garcia, D.6
Sagot, M.A.7
Barritault, D.8
Caruelle, J.P.9
Kern, P.10
-
6
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y., and Massagué J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113 (2003) 685-690
-
(2003)
Cell
, vol.113
, pp. 685-690
-
-
Shi, Y.1
Massagué, J.2
-
7
-
-
0038515329
-
Role of cyclooxygenase 2 in protein kinase C beta II-mediated colon carcinogenesis
-
Yu W., Murray N.R., Weems C., Chen L., Guo H., Ethridge R., et al. Role of cyclooxygenase 2 in protein kinase C beta II-mediated colon carcinogenesis. J Biol Chem 278 (2003) 11167-11174
-
(2003)
J Biol Chem
, vol.278
, pp. 11167-11174
-
-
Yu, W.1
Murray, N.R.2
Weems, C.3
Chen, L.4
Guo, H.5
Ethridge, R.6
-
8
-
-
1542313954
-
Transforming growth factor beta and atherosclerosis: so far, so good for the protective cytokine hypothesis
-
Grainger D.J. Transforming growth factor beta and atherosclerosis: so far, so good for the protective cytokine hypothesis. Arterioscler Thromb Vasc Biol 24 (2004) 399-404
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 399-404
-
-
Grainger, D.J.1
-
9
-
-
0032866397
-
The expression of TGF-beta receptors in human atherosclerosis: evidence for acquired resistance to apoptosis due to receptor imbalance
-
McCaffrey T.A., Du B., Fu C., Bray P.J., Sanborn T.A., Deutsch E., et al. The expression of TGF-beta receptors in human atherosclerosis: evidence for acquired resistance to apoptosis due to receptor imbalance. J Mol Cell Cardiol 31 (1999) 1627-1642
-
(1999)
J Mol Cell Cardiol
, vol.31
, pp. 1627-1642
-
-
McCaffrey, T.A.1
Du, B.2
Fu, C.3
Bray, P.J.4
Sanborn, T.A.5
Deutsch, E.6
-
10
-
-
0037598870
-
Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover
-
Di Guglielmo G.M., Le Roy C., Goodfellow A.F., and Wrana J.L. Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover. Nat Cell Biol 5 (2003) 410-421
-
(2003)
Nat Cell Biol
, vol.5
, pp. 410-421
-
-
Di Guglielmo, G.M.1
Le Roy, C.2
Goodfellow, A.F.3
Wrana, J.L.4
-
11
-
-
2342488852
-
New insights into TGF-beta-Smad signalling
-
Ten Dijke P., and Hill C.S. New insights into TGF-beta-Smad signalling. Trends Biochem Sci 29 (2004) 265-273
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 265-273
-
-
Ten Dijke, P.1
Hill, C.S.2
-
12
-
-
14644439839
-
Pioglitazone induces vascular smooth muscle cell apoptosis through a peroxisome proliferator-activated receptor-gamma, transforming growth factor-beta1, and a Smad2-dependent mechanism
-
Redondo S., Ruiz E., Santos-Gallego C.G., Padilla E., and Tejerina T. Pioglitazone induces vascular smooth muscle cell apoptosis through a peroxisome proliferator-activated receptor-gamma, transforming growth factor-beta1, and a Smad2-dependent mechanism. Diabetes 54 (2005) 811-817
-
(2005)
Diabetes
, vol.54
, pp. 811-817
-
-
Redondo, S.1
Ruiz, E.2
Santos-Gallego, C.G.3
Padilla, E.4
Tejerina, T.5
-
13
-
-
0033534573
-
Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3
-
Yagi K., Goto D., Hamamoto T., Takenoshita S., Kato M., and Miyazono K. Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3. J Biol Chem 274 (1999) 703-709
-
(1999)
J Biol Chem
, vol.274
, pp. 703-709
-
-
Yagi, K.1
Goto, D.2
Hamamoto, T.3
Takenoshita, S.4
Kato, M.5
Miyazono, K.6
-
15
-
-
8144230707
-
Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction
-
Lebrin F., Goumans M.J., Jonker L., Carvalho R.L., Valdimarsdottir G., Thorikay M., et al. Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction. EMBO J 23 (2004) 4018-4028
-
(2004)
EMBO J
, vol.23
, pp. 4018-4028
-
-
Lebrin, F.1
Goumans, M.J.2
Jonker, L.3
Carvalho, R.L.4
Valdimarsdottir, G.5
Thorikay, M.6
-
16
-
-
12544257249
-
Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo
-
Kamaraju A.K., and Roberts A.B. Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo. J Biol Chem 280 (2005) 1024-1036
-
(2005)
J Biol Chem
, vol.280
, pp. 1024-1036
-
-
Kamaraju, A.K.1
Roberts, A.B.2
-
17
-
-
27744494454
-
TGF-{beta}-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent
-
Seay U., Sedding D., Krick S., Hecker M., Seeger W., and Eickelberg O. TGF-{beta}-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent. J Pharmacol Exp Ther 315 (2005) 1005-1012
-
(2005)
J Pharmacol Exp Ther
, vol.315
, pp. 1005-1012
-
-
Seay, U.1
Sedding, D.2
Krick, S.3
Hecker, M.4
Seeger, W.5
Eickelberg, O.6
-
18
-
-
0346690411
-
TGF- beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest
-
Bhowmick N.A., Ghiassi M., Aakre M., Brown K., Singh V., and Moses H.L. TGF- beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest. Proc Natl Acad Sci USA 100 (2003) 15548-15553
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15548-15553
-
-
Bhowmick, N.A.1
Ghiassi, M.2
Aakre, M.3
Brown, K.4
Singh, V.5
Moses, H.L.6
-
20
-
-
4644284605
-
A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells
-
Bakin A.V., Safina A., Rinehart C., Daroqui C., Darbary H., and Helfman D.M. A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells. Mol Biol Cell 15 (2004) 4682-4694
-
(2004)
Mol Biol Cell
, vol.15
, pp. 4682-4694
-
-
Bakin, A.V.1
Safina, A.2
Rinehart, C.3
Daroqui, C.4
Darbary, H.5
Helfman, D.M.6
-
21
-
-
10344262906
-
Regulation of the cytoskeleton: an oncogenic function for CDK inhibitors?
-
Besson A., Assoian R.K., and Roberts J.M. Regulation of the cytoskeleton: an oncogenic function for CDK inhibitors?. Nat Rev Cancer 4 (2005) 948-955
-
(2005)
Nat Rev Cancer
, vol.4
, pp. 948-955
-
-
Besson, A.1
Assoian, R.K.2
Roberts, J.M.3
-
22
-
-
0024563645
-
Vascular smooth muscle cells express distinct transforming growth factor-beta receptor phenotypes as a function of cell density in culture
-
Goodman L.V., and Majack R.A. Vascular smooth muscle cells express distinct transforming growth factor-beta receptor phenotypes as a function of cell density in culture. J Biol Chem 264 (1989) 5241-5244
-
(1989)
J Biol Chem
, vol.264
, pp. 5241-5244
-
-
Goodman, L.V.1
Majack, R.A.2
-
23
-
-
1642382023
-
Transforming growth factor- beta-induced inhibition of myogenesis is mediated through Smad pathway and is modulated by microtubule dynamic stability
-
Zhu S., Goldschmidt-Clermont P.J., and Dong C. Transforming growth factor- beta-induced inhibition of myogenesis is mediated through Smad pathway and is modulated by microtubule dynamic stability. Circ Res 94 (2004) 617-625
-
(2004)
Circ Res
, vol.94
, pp. 617-625
-
-
Zhu, S.1
Goldschmidt-Clermont, P.J.2
Dong, C.3
-
24
-
-
0033969934
-
Microtubule binding to Smads may regulate TGF beta activity
-
Dong C., Li Z., Alvarez Jr. R., Feng X.H., and Goldschmidt-Clermont P.J. Microtubule binding to Smads may regulate TGF beta activity. Mol Cell 5 (2000) 27-34
-
(2000)
Mol Cell
, vol.5
, pp. 27-34
-
-
Dong, C.1
Li, Z.2
Alvarez Jr., R.3
Feng, X.H.4
Goldschmidt-Clermont, P.J.5
-
25
-
-
0033601179
-
Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription
-
Engel M.E., McDonnell M.A., Law B.K., and Moses H.L. Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription. J Biol Chem 274 (1999) 37413-37420
-
(1999)
J Biol Chem
, vol.274
, pp. 37413-37420
-
-
Engel, M.E.1
McDonnell, M.A.2
Law, B.K.3
Moses, H.L.4
-
26
-
-
0036773855
-
The role of transforming growth factor beta in atherosclerosis: novel insights and future perspectives
-
Mallat Z., and Tedgui A. The role of transforming growth factor beta in atherosclerosis: novel insights and future perspectives. Curr Opin Lipidol 13 (2002) 523-529
-
(2002)
Curr Opin Lipidol
, vol.13
, pp. 523-529
-
-
Mallat, Z.1
Tedgui, A.2
-
27
-
-
11144224296
-
Immunomodulation of atherosclerosis: implications for vaccine development
-
Nillson J., Hansson G.K., and Shah P.K. Immunomodulation of atherosclerosis: implications for vaccine development. Arterioscler Thromb Vasc Biol 25 (2005) 18-28
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 18-28
-
-
Nillson, J.1
Hansson, G.K.2
Shah, P.K.3
-
28
-
-
0035879091
-
Regulation of TGF-beta response during T cell activation is modulated by IL-10
-
Cottrez F., and Groux H. Regulation of TGF-beta response during T cell activation is modulated by IL-10. J Immunol 167 (2001) 773-838
-
(2001)
J Immunol
, vol.167
, pp. 773-838
-
-
Cottrez, F.1
Groux, H.2
-
29
-
-
0034131557
-
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
-
Gorelik L., and Flavell R.A. Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 12 2 (2000) 171-181
-
(2000)
Immunity
, vol.12
, Issue.2
, pp. 171-181
-
-
Gorelik, L.1
Flavell, R.A.2
-
30
-
-
17144400393
-
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4 + CD25 + regulatory T cells
-
Marie J.C., Letterio J.J., Gavin M., and Rudensky A.Y. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4 + CD25 + regulatory T cells. J Exp Med 201 (2005) 1061-1067
-
(2005)
J Exp Med
, vol.201
, pp. 1061-1067
-
-
Marie, J.C.1
Letterio, J.J.2
Gavin, M.3
Rudensky, A.Y.4
-
31
-
-
32244445416
-
Natural regulatory T cells control the development of atherosclerosis in mice
-
Ait-Oufella H., Salomon B.L., Potteaux S., Robertson A.K., Gourdy P., Zoll J., Merval R., Esposito B., Cohen J.L., Fisson S., Flavell R.A., Hansson G.K., Klatzmann D., Tedgui A., and Mallat Z. Natural regulatory T cells control the development of atherosclerosis in mice. Nat Med 12 2 (2006) 178-180
-
(2006)
Nat Med
, vol.12
, Issue.2
, pp. 178-180
-
-
Ait-Oufella, H.1
Salomon, B.L.2
Potteaux, S.3
Robertson, A.K.4
Gourdy, P.5
Zoll, J.6
Merval, R.7
Esposito, B.8
Cohen, J.L.9
Fisson, S.10
Flavell, R.A.11
Hansson, G.K.12
Klatzmann, D.13
Tedgui, A.14
Mallat, Z.15
-
32
-
-
0028918825
-
The serum concentration of active transforming growth factor-beta is severely depressed in advanced atherosclerosis
-
Grainger D.J., Kemp P.R., Metcalfe J.C., Liu A.C., Lawn R.M., Williams N.R., et al. The serum concentration of active transforming growth factor-beta is severely depressed in advanced atherosclerosis. Nat Med 1 (1995) 174-179
-
(1995)
Nat Med
, vol.1
, pp. 174-179
-
-
Grainger, D.J.1
Kemp, P.R.2
Metcalfe, J.C.3
Liu, A.C.4
Lawn, R.M.5
Williams, N.R.6
-
33
-
-
11244341059
-
Stimulation of vascular smooth muscle cell proliferation and migration by apolipoprotein(a) is dependent on inhibition of transforming growth factor-beta activation and on the presence of kringle IV type 9
-
O'Neil C.H., Boffa M.B., Hancock M.A., Pickering J.G., and Koschinsky M.L. Stimulation of vascular smooth muscle cell proliferation and migration by apolipoprotein(a) is dependent on inhibition of transforming growth factor-beta activation and on the presence of kringle IV type 9. J Biol Chem 279 (2004) 55187-55195
-
(2004)
J Biol Chem
, vol.279
, pp. 55187-55195
-
-
O'Neil, C.H.1
Boffa, M.B.2
Hancock, M.A.3
Pickering, J.G.4
Koschinsky, M.L.5
-
34
-
-
0032171433
-
Increasde PAI activity and PAI-1 antigen occurring with an oral fat load: associations with PAI-1 genotype and plasma active TGF-beta levels
-
Byrne C.D., Wareham N.J., Martensz N.D., Humphries S.E., Metcalfe J.C., and Grainger D.J. Increasde PAI activity and PAI-1 antigen occurring with an oral fat load: associations with PAI-1 genotype and plasma active TGF-beta levels. Atherosclerosis 140 (1998) 45-53
-
(1998)
Atherosclerosis
, vol.140
, pp. 45-53
-
-
Byrne, C.D.1
Wareham, N.J.2
Martensz, N.D.3
Humphries, S.E.4
Metcalfe, J.C.5
Grainger, D.J.6
-
35
-
-
3943049366
-
Smad expression in human atherosclerotic lesions: evidence for impaired TGF-beta/Smad signaling in smooth muscle cells of fibrofatty lesions
-
Kalinina N., Agrotis A., Antropova Y., Ilyinskaya O., Smirnov V., Tararak E., et al. Smad expression in human atherosclerotic lesions: evidence for impaired TGF-beta/Smad signaling in smooth muscle cells of fibrofatty lesions. Arterioscler Thromb Vasc Biol 224 (2004) 1391-1396
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.224
, pp. 1391-1396
-
-
Kalinina, N.1
Agrotis, A.2
Antropova, Y.3
Ilyinskaya, O.4
Smirnov, V.5
Tararak, E.6
-
36
-
-
12644260471
-
Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium
-
Topper J.N., Cai J., Qiu Y., Anderson K.R., Xu Y.Y., Deeds J.D., et al. Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proc Natl Acad Sci USA 19 (1997) 9314-9349
-
(1997)
Proc Natl Acad Sci USA
, vol.19
, pp. 9314-9349
-
-
Topper, J.N.1
Cai, J.2
Qiu, Y.3
Anderson, K.R.4
Xu, Y.Y.5
Deeds, J.D.6
-
37
-
-
0030704297
-
Genomic instability in the type II TGF-beta 1 receptor gene in atherosclerotic and restenotic vascular cells
-
McCaffrey T.A., Du B.H., Consigli S., Szabo P., Bray P.J., Hartner L., et al. Genomic instability in the type II TGF-beta 1 receptor gene in atherosclerotic and restenotic vascular cells. J Clin Invest 100 (1997) 2182-2228
-
(1997)
J Clin Invest
, vol.100
, pp. 2182-2228
-
-
McCaffrey, T.A.1
Du, B.H.2
Consigli, S.3
Szabo, P.4
Bray, P.J.5
Hartner, L.6
-
38
-
-
0035051529
-
Microsatellite mutation of type II transforming growth factor-beta receptor is rare in atherosclerotic plaques
-
Clark K.J., Cary N.R., Grace A.A., and Metcalfe J.C. Microsatellite mutation of type II transforming growth factor-beta receptor is rare in atherosclerotic plaques. Arterioscler Thromb Vasc Biol 4 (2001) 555-559
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.4
, pp. 555-559
-
-
Clark, K.J.1
Cary, N.R.2
Grace, A.A.3
Metcalfe, J.C.4
-
39
-
-
0035834818
-
Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice
-
Mallat Z., Gojova A., Marchiol-Fournigault C., Esposito B., Kamate C., Merval R., et al. Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice. Circ Res 89 (2001) 930-940
-
(2001)
Circ Res
, vol.89
, pp. 930-940
-
-
Mallat, Z.1
Gojova, A.2
Marchiol-Fournigault, C.3
Esposito, B.4
Kamate, C.5
Merval, R.6
-
40
-
-
0036078307
-
Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression
-
Lutgens E., Gijbels M., Smook M., Heeringa P., Gotwals P., Koteliansky V.E., et al. Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression. Arterioscler Thromb Vasc Biol 22 (2002) 975-982
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 975-982
-
-
Lutgens, E.1
Gijbels, M.2
Smook, M.3
Heeringa, P.4
Gotwals, P.5
Koteliansky, V.E.6
-
41
-
-
0035026639
-
Upregulatory expression of furin and transforming growth factor-beta by fluid shear stress in vascular endothelial cells
-
Negishi M., Lu D., Zhang Y.Q., Sawada Y., Sasaki T., Kayo T., et al. Upregulatory expression of furin and transforming growth factor-beta by fluid shear stress in vascular endothelial cells. Arterioscler Thromb Vasc Biol 21 (2001) 785-790
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 785-790
-
-
Negishi, M.1
Lu, D.2
Zhang, Y.Q.3
Sawada, Y.4
Sasaki, T.5
Kayo, T.6
-
42
-
-
0035403085
-
Up-regulation of the fibrogenic cytokine TGF-beta1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis
-
Leonarduzzi G., Sevanian A., Sottero B., Arkan M.C., Biasi F., Chiarpotto E., et al. Up-regulation of the fibrogenic cytokine TGF-beta1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis. FASEB J 15 (2001) 1619-1621
-
(2001)
FASEB J
, vol.15
, pp. 1619-1621
-
-
Leonarduzzi, G.1
Sevanian, A.2
Sottero, B.3
Arkan, M.C.4
Biasi, F.5
Chiarpotto, E.6
-
43
-
-
0032968645
-
Differential regulation of transforming growth factor receptors by angiotensin II and transforming growth factor-beta1 in vascular smooth muscle
-
Siegert A., Ritz E., Orth S., and Wagner J. Differential regulation of transforming growth factor receptors by angiotensin II and transforming growth factor-beta1 in vascular smooth muscle. J Mol Med 77 (1999) 437-445
-
(1999)
J Mol Med
, vol.77
, pp. 437-445
-
-
Siegert, A.1
Ritz, E.2
Orth, S.3
Wagner, J.4
-
44
-
-
0037417931
-
Acetylsalicylic acid inhibits cell proliferation by involving transforming growth factor-beta
-
Redondo S., Santos-Gallego C.G., Ganado P., Garcia M., Rico L., Del Rio M., et al. Acetylsalicylic acid inhibits cell proliferation by involving transforming growth factor-beta. Circulation 107 (2003) 626-629
-
(2003)
Circulation
, vol.107
, pp. 626-629
-
-
Redondo, S.1
Santos-Gallego, C.G.2
Ganado, P.3
Garcia, M.4
Rico, L.5
Del Rio, M.6
-
45
-
-
4744371004
-
Increased expression of transforming growth factor-beta1 as a stabilizing factor in human atherosclerotic plaques
-
Cipollone F., Fazia M., Mincione G., Iezzi A., Pini B., Cuccurullo C., et al. Increased expression of transforming growth factor-beta1 as a stabilizing factor in human atherosclerotic plaques. Stroke 35 (2004) 2253-2257
-
(2004)
Stroke
, vol.35
, pp. 2253-2257
-
-
Cipollone, F.1
Fazia, M.2
Mincione, G.3
Iezzi, A.4
Pini, B.5
Cuccurullo, C.6
-
46
-
-
23044466787
-
Protein and mRNA expression levels of VEGF-A and TGF-beta1 in different types of human coronary atherosclerotic lesions
-
Panutsopulos D., Papalambros E., Sigala F., Zafiropoulos A., Arvanitis D.L., and Spandidos D.A. Protein and mRNA expression levels of VEGF-A and TGF-beta1 in different types of human coronary atherosclerotic lesions. Int J Mol Med 15 (2005) 603-610
-
(2005)
Int J Mol Med
, vol.15
, pp. 603-610
-
-
Panutsopulos, D.1
Papalambros, E.2
Sigala, F.3
Zafiropoulos, A.4
Arvanitis, D.L.5
Spandidos, D.A.6
-
47
-
-
0030994625
-
Circulating transforming growth factor beta 1 and coronary artery disease
-
Wang X.L., Liu S.X., and Wilcken D.E. Circulating transforming growth factor beta 1 and coronary artery disease. Cardiovasc Res 34 (1998) 404-410
-
(1998)
Cardiovasc Res
, vol.34
, pp. 404-410
-
-
Wang, X.L.1
Liu, S.X.2
Wilcken, D.E.3
-
48
-
-
0033779229
-
Transforming growth factor beta in hypertensives with cardiorenal damage
-
Laviades C., Varo N., and Diez J. Transforming growth factor beta in hypertensives with cardiorenal damage. Hypertension 36 (2000) 517-522
-
(2000)
Hypertension
, vol.36
, pp. 517-522
-
-
Laviades, C.1
Varo, N.2
Diez, J.3
-
49
-
-
0038235848
-
Association between transforming growth factor-beta and hypertension
-
Lijnen P.J., Petrov V.V., and Fagard R.H. Association between transforming growth factor-beta and hypertension. Am J Hypertens 16 (2003) 604-611
-
(2003)
Am J Hypertens
, vol.16
, pp. 604-611
-
-
Lijnen, P.J.1
Petrov, V.V.2
Fagard, R.H.3
-
50
-
-
0037132676
-
Enhanced extracellular matrix accumulation in restenosis of coronary arteries after stent deployment
-
Chung I.M., Gold H.K., Schwartz S.M., Ikari Y., Reidy M.A., and Wight T.N. Enhanced extracellular matrix accumulation in restenosis of coronary arteries after stent deployment. J Am Coll Cardiol 40 (2002) 2072-2081
-
(2002)
J Am Coll Cardiol
, vol.40
, pp. 2072-2081
-
-
Chung, I.M.1
Gold, H.K.2
Schwartz, S.M.3
Ikari, Y.4
Reidy, M.A.5
Wight, T.N.6
-
51
-
-
0034745179
-
TGF beta is active, and correlates with activators of TGF beta, following porcine coronary angioplasty
-
Chamberlain J., Gunn J., Francis S.E., Holt C.M., Arnold N.D., Cumberland D.C., et al. TGF beta is active, and correlates with activators of TGF beta, following porcine coronary angioplasty. Cardiovasc Res 50 (2001) 125-136
-
(2001)
Cardiovasc Res
, vol.50
, pp. 125-136
-
-
Chamberlain, J.1
Gunn, J.2
Francis, S.E.3
Holt, C.M.4
Arnold, N.D.5
Cumberland, D.C.6
-
52
-
-
0033612364
-
Soluble transforming growth factor-beta type II receptor inhibits negative remodeling, fibroblast transdifferentiation, and intimal lesion formation but not endothelial growth
-
Smith J.D., Bryant S.R., Couper L.L., Vary C.P., Gotwals P.J., Koteliansky V.E., et al. Soluble transforming growth factor-beta type II receptor inhibits negative remodeling, fibroblast transdifferentiation, and intimal lesion formation but not endothelial growth. Circ Res 84 (1999) 1212-1222
-
(1999)
Circ Res
, vol.84
, pp. 1212-1222
-
-
Smith, J.D.1
Bryant, S.R.2
Couper, L.L.3
Vary, C.P.4
Gotwals, P.J.5
Koteliansky, V.E.6
-
53
-
-
0035923567
-
Adenovirus-mediated gene transfer of a secreted transforming growth factor-beta type II receptor inhibits luminal loss and constrictive remodelling after coronary angioplasty and enhances adventitial collagen deposition
-
Kingston P.A., Sinha S., David A., Castro M.G., Lowenstein P.R., and Heagerty A.M. Adenovirus-mediated gene transfer of a secreted transforming growth factor-beta type II receptor inhibits luminal loss and constrictive remodelling after coronary angioplasty and enhances adventitial collagen deposition. Circulation 104 (2001) 2595-2601
-
(2001)
Circulation
, vol.104
, pp. 2595-2601
-
-
Kingston, P.A.1
Sinha, S.2
David, A.3
Castro, M.G.4
Lowenstein, P.R.5
Heagerty, A.M.6
-
54
-
-
16644369282
-
Endothelial progenitor cells: characterization, pathophysiology, and possible clinical relevance
-
Hristov M., and Weber C. Endothelial progenitor cells: characterization, pathophysiology, and possible clinical relevance. J Cell Mol Med 8 (2004) 498-508
-
(2004)
J Cell Mol Med
, vol.8
, pp. 498-508
-
-
Hristov, M.1
Weber, C.2
-
55
-
-
21244432808
-
Serum derived from multiple trauma patients promotes the differentiation of endothelial progenitor cells in vitro: possible role of transforming growth factor-beta1 and vascular endothelial growth factor 165
-
Henrich D., Hahn P., Wahl M., Wilhelm K., Dernbach E., Dimmeler S., et al. Serum derived from multiple trauma patients promotes the differentiation of endothelial progenitor cells in vitro: possible role of transforming growth factor-beta1 and vascular endothelial growth factor 165. Shock 21 (2004) 13-16
-
(2004)
Shock
, vol.21
, pp. 13-16
-
-
Henrich, D.1
Hahn, P.2
Wahl, M.3
Wilhelm, K.4
Dernbach, E.5
Dimmeler, S.6
-
56
-
-
14044270110
-
Potent inhibitory effect of sirolimus on circulating vascular progenitor cells
-
Fukuda D., Sata M., Tanaka K., and Nagai R. Potent inhibitory effect of sirolimus on circulating vascular progenitor cells. Circulation 111 (2005) 926-931
-
(2005)
Circulation
, vol.111
, pp. 926-931
-
-
Fukuda, D.1
Sata, M.2
Tanaka, K.3
Nagai, R.4
-
57
-
-
33745503676
-
Characterization of smooth muscle-like cells in circulating human peripheral blood
-
Sugiyama S., Kugiyama K., Nakamura S., Kataoka K., Aikawa M., Shimizu K., Koide S., Mitchell R.N., Ogawa H., and Libby P. Characterization of smooth muscle-like cells in circulating human peripheral blood. Atherosclerosis 187 (2006) 351-362
-
(2006)
Atherosclerosis
, vol.187
, pp. 351-362
-
-
Sugiyama, S.1
Kugiyama, K.2
Nakamura, S.3
Kataoka, K.4
Aikawa, M.5
Shimizu, K.6
Koide, S.7
Mitchell, R.N.8
Ogawa, H.9
Libby, P.10
-
58
-
-
33744959772
-
Transforming growth factor-beta signaling enhances transdifferentiation of macrophages into smooth muscle-like cells
-
Ninomiya K., Takahashi A., Fujioka Y., Ishikawa Y., and Yokoyama M. Transforming growth factor-beta signaling enhances transdifferentiation of macrophages into smooth muscle-like cells. Hypertens Res 29 (2006) 269-276
-
(2006)
Hypertens Res
, vol.29
, pp. 269-276
-
-
Ninomiya, K.1
Takahashi, A.2
Fujioka, Y.3
Ishikawa, Y.4
Yokoyama, M.5
-
59
-
-
0037439630
-
Making sense of latent TGF beta activation
-
Annes J.P., Munger J.S., and Rifkin D.B. Making sense of latent TGF beta activation. J Cell Sci 116 (2003) 217-224
-
(2003)
J Cell Sci
, vol.116
, pp. 217-224
-
-
Annes, J.P.1
Munger, J.S.2
Rifkin, D.B.3
-
60
-
-
0042834368
-
Glucose-induced TGF-beta1 and TGF-beta receptor-1 expression in vascular smooth muscle cells is mediated by protein kinase C-alpha
-
Lindschau C., Quass P., Menne J., Guler F., Fiebeler A., Leitges M., et al. Glucose-induced TGF-beta1 and TGF-beta receptor-1 expression in vascular smooth muscle cells is mediated by protein kinase C-alpha. Hypertension 42 (2003) 335-341
-
(2003)
Hypertension
, vol.42
, pp. 335-341
-
-
Lindschau, C.1
Quass, P.2
Menne, J.3
Guler, F.4
Fiebeler, A.5
Leitges, M.6
-
61
-
-
0037141103
-
Disruption of transforming growth factor beta signaling by a novel ligand-dependent mechanism
-
Fernandez T., Amoroso S., Sharpe S., Jones G.M., Bliskovski V., Kovalchuk A., et al. Disruption of transforming growth factor beta signaling by a novel ligand-dependent mechanism. J Exp Med 20 (2004) 1247-1255
-
(2004)
J Exp Med
, vol.20
, pp. 1247-1255
-
-
Fernandez, T.1
Amoroso, S.2
Sharpe, S.3
Jones, G.M.4
Bliskovski, V.5
Kovalchuk, A.6
-
62
-
-
10344243008
-
Polymorphisms of the transforming growth factor-beta 1 gene in relation to myocardial infarction and blood pressure. The Etude Cas-Temoin de l'Infarctus du Myocarde (ECTIM) Study
-
Cambien F., Ricard S., Troesch A., Mallet C., Generenaz L., Evans A., et al. Polymorphisms of the transforming growth factor-beta 1 gene in relation to myocardial infarction and blood pressure. The Etude Cas-Temoin de l'Infarctus du Myocarde (ECTIM) Study. Hypertension 28 (1996) 881-887
-
(1996)
Hypertension
, vol.28
, pp. 881-887
-
-
Cambien, F.1
Ricard, S.2
Troesch, A.3
Mallet, C.4
Generenaz, L.5
Evans, A.6
-
63
-
-
0034690805
-
Association of a T29 → C polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to myocardial infarction in Japanese
-
Yokota M., Ichihara S., Lin T.L., Nakashima N., and Yamada Y. Association of a T29 → C polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to myocardial infarction in Japanese. Circulation 101 (2002) 2783-2787
-
(2002)
Circulation
, vol.101
, pp. 2783-2787
-
-
Yokota, M.1
Ichihara, S.2
Lin, T.L.3
Nakashima, N.4
Yamada, Y.5
-
64
-
-
0034604110
-
Role of transforming growth factor beta in human disease
-
Blobe G.C., Schiemann W.P., and Lodish H.F. Role of transforming growth factor beta in human disease. N Engl J Med 342 (2000) 1350-1358
-
(2000)
N Engl J Med
, vol.342
, pp. 1350-1358
-
-
Blobe, G.C.1
Schiemann, W.P.2
Lodish, H.F.3
-
65
-
-
16444364523
-
Platelets and chemokines in atherosclerosis: partners in crime
-
Weber C. Platelets and chemokines in atherosclerosis: partners in crime. Circ Res 96 (2005) 612-616
-
(2005)
Circ Res
, vol.96
, pp. 612-616
-
-
Weber, C.1
-
66
-
-
0033611576
-
Transformation of intestinal epithelial cells by chronic TGF-beta1 treatment results in downregulation of the type II TGF-beta receptor and induction of cyclooxygenase-2
-
Sheng H., Shao J., O'Mahony C.A., Lamps L., Albo D., Isakson P.C., et al. Transformation of intestinal epithelial cells by chronic TGF-beta1 treatment results in downregulation of the type II TGF-beta receptor and induction of cyclooxygenase-2. Oncogene 18 (1999) 855-867
-
(1999)
Oncogene
, vol.18
, pp. 855-867
-
-
Sheng, H.1
Shao, J.2
O'Mahony, C.A.3
Lamps, L.4
Albo, D.5
Isakson, P.C.6
-
67
-
-
10444261212
-
Development of TGF-beta signalling inhibitors for cancer therapy
-
Yingling J.M., Blanchard K.L., and Sawyer J.S. Development of TGF-beta signalling inhibitors for cancer therapy. Nat Rev Drug Discov 3 (2004) 1011-1022
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 1011-1022
-
-
Yingling, J.M.1
Blanchard, K.L.2
Sawyer, J.S.3
-
68
-
-
0038205926
-
Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat
-
Benigni A., Zoja C., Corna D., Zatelli C., Conti S., Campana M., et al. Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat. J Am Soc Nephrol 14 (2003) 1816-1824
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1816-1824
-
-
Benigni, A.1
Zoja, C.2
Corna, D.3
Zatelli, C.4
Conti, S.5
Campana, M.6
-
69
-
-
0041342109
-
Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery
-
Mead A.L., Wong T.T., Cordeiro M.F., Anderson I.K., and Khaw P.T. Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery. Invest Ophthalmol Vis Sci 44 (2003) 3394-3401
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 3394-3401
-
-
Mead, A.L.1
Wong, T.T.2
Cordeiro, M.F.3
Anderson, I.K.4
Khaw, P.T.5
-
70
-
-
19444371555
-
Inhibition of gene markers of fibrosis with a novel inhibitor of TGF{beta}-type I receptor kinase in puromycin-induced nephritis
-
Grygielko E.T., Martin W.M., Tweed C.W., Thornton P.P., Harling J.D., Brooks D.P., et al. Inhibition of gene markers of fibrosis with a novel inhibitor of TGF{beta}-type I receptor kinase in puromycin-induced nephritis. J Pharmacol Exp Ther 313 (2005) 943-951
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 943-951
-
-
Grygielko, E.T.1
Martin, W.M.2
Tweed, C.W.3
Thornton, P.P.4
Harling, J.D.5
Brooks, D.P.6
-
71
-
-
19944421105
-
Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis
-
De Gouville A.C., Boullay V., Krysa G., Pilot J., Brusq J.M., Loriolle F., et al. Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis. Br J Pharmacol 145 (2005) 166-177
-
(2005)
Br J Pharmacol
, vol.145
, pp. 166-177
-
-
De Gouville, A.C.1
Boullay, V.2
Krysa, G.3
Pilot, J.4
Brusq, J.M.5
Loriolle, F.6
-
72
-
-
20244383986
-
Progressive transforming growth factor {beta}1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor
-
Bonniaud P., Margetts P.J., Kolb M., Schroeder J.A., Kapoun A.M., Damm D., et al. Progressive transforming growth factor {beta}1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor. Am J Respir Crit Care Med 171 (2005) 889-898
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 889-898
-
-
Bonniaud, P.1
Margetts, P.J.2
Kolb, M.3
Schroeder, J.A.4
Kapoun, A.M.5
Damm, D.6
-
73
-
-
0036085920
-
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
-
Inman G.J., Nicolas F.J., Callahan J.F., Harling J.D., Gaster L.M., Reith A.D., et al. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol 62 (2002) 65-74
-
(2002)
Mol Pharmacol
, vol.62
, pp. 65-74
-
-
Inman, G.J.1
Nicolas, F.J.2
Callahan, J.F.3
Harling, J.D.4
Gaster, L.M.5
Reith, A.D.6
-
74
-
-
10744225133
-
SB-431542 and Gleevec inhibit transforming growth factor-beta- induced proliferation of human osteosarcoma cells
-
Matsuyama S., Iwadate M., Kondo M., Saitoh M., Hanyu A., Shimizu K., et al. SB-431542 and Gleevec inhibit transforming growth factor-beta- induced proliferation of human osteosarcoma cells. Cancer Res 63 (2003) 7791-7798
-
(2003)
Cancer Res
, vol.63
, pp. 7791-7798
-
-
Matsuyama, S.1
Iwadate, M.2
Kondo, M.3
Saitoh, M.4
Hanyu, A.5
Shimizu, K.6
-
75
-
-
31044448265
-
Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression
-
Jinnin M., Ihn H., and Tamaki K. Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression. Mol Pharmacol 69 (2006) 597-607
-
(2006)
Mol Pharmacol
, vol.69
, pp. 597-607
-
-
Jinnin, M.1
Ihn, H.2
Tamaki, K.3
-
76
-
-
0037024272
-
Increased transforming growth factor-beta(1) circulating levels and production in human monocytes after 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase inhibition with pravastatin
-
Porreca E., Di Febbo C., Baccante G., Di Nisio M., and Cuccurullo F. Increased transforming growth factor-beta(1) circulating levels and production in human monocytes after 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase inhibition with pravastatin. J Am Coll Cardiol 39 (2002) 1752-1757
-
(2002)
J Am Coll Cardiol
, vol.39
, pp. 1752-1757
-
-
Porreca, E.1
Di Febbo, C.2
Baccante, G.3
Di Nisio, M.4
Cuccurullo, F.5
-
77
-
-
0346729955
-
Peroxisome proliferator-activated receptor-gamma ligands inhibit TGF-beta 1-induced fibronectin expression in glomerular mesangial cells
-
Guo B., Koya D., Isono M., Sugimoto T., Kashiwagi A., and Haneda M. Peroxisome proliferator-activated receptor-gamma ligands inhibit TGF-beta 1-induced fibronectin expression in glomerular mesangial cells. Diabetes 53 (2004) 200-208
-
(2004)
Diabetes
, vol.53
, pp. 200-208
-
-
Guo, B.1
Koya, D.2
Isono, M.3
Sugimoto, T.4
Kashiwagi, A.5
Haneda, M.6
-
78
-
-
9144227431
-
Long-term inhibition of rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries: involvement of multiple mechanisms
-
Matsumoto Y., Uwatoku T., Oi K., Abe K., Hattori T., Morishige K., et al. Long-term inhibition of rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries: involvement of multiple mechanisms. Arterioscler Thromb Vasc Biol 24 (2004) 181-186
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 181-186
-
-
Matsumoto, Y.1
Uwatoku, T.2
Oi, K.3
Abe, K.4
Hattori, T.5
Morishige, K.6
-
79
-
-
0031766033
-
Angiotensin converting enzyme inhibition reduces the expression of transforming growth factor-beta1 and type IV collagen in diabetic vasculopathy
-
Rumble J.R., Gilbert R.E., Cox A., Wu L., and Cooper M.E. Angiotensin converting enzyme inhibition reduces the expression of transforming growth factor-beta1 and type IV collagen in diabetic vasculopathy. J Hypertens 16 (1998) 1603-1609
-
(1998)
J Hypertens
, vol.16
, pp. 1603-1609
-
-
Rumble, J.R.1
Gilbert, R.E.2
Cox, A.3
Wu, L.4
Cooper, M.E.5
|