메뉴 건너뛰기




Volumn 579, Issue , 2006, Pages 98-107

Overview of role of the immune system in the pathogenesis of inflammatory bowel disease

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; HUMANS; IMMUNITY, CELLULAR; INFLAMMATORY BOWEL DISEASES;

EID: 34249823876     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/0-387-33778-4_6     Document Type: Review
Times cited : (15)

References (67)
  • 1
    • 0024260960 scopus 로고
    • Remission of Crohn's disease after human immunodeficiency virus infection
    • James SP. Remission of Crohn's disease after human immunodeficiency virus infection. Gastroenterology 1988; 95:1667-1669.
    • (1988) Gastroenterology , vol.95 , pp. 1667-1669
    • James, S.P.1
  • 2
    • 0026552488 scopus 로고
    • Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ukerative colitis
    • Mullin GE, Lazenby AJ, Harris ML et al. Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ukerative colitis. Gastroenterology 1992; 102:1620-1627.
    • (1992) Gastroenterology , vol.102 , pp. 1620-1627
    • Mullin, G.E.1    Lazenby, A.J.2    Harris, M.L.3
  • 3
    • 0027441514 scopus 로고
    • Interleukin-2- and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa
    • Breese E, Braegger CP, Corrigan CJ et al. Interleukin-2- and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa. Immunology 1993; 78:127-131.
    • (1993) Immunology , vol.78 , pp. 127-131
    • Breese, E.1    Braegger, C.P.2    Corrigan, C.J.3
  • 4
    • 0030209985 scopus 로고    scopus 로고
    • Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
    • Fuss IJ, Neurath M, Boirivant M et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 1996; 157:1261-1270.
    • (1996) J Immunol , vol.157 , pp. 1261-1270
    • Fuss, I.J.1    Neurath, M.2    Boirivant, M.3
  • 5
    • 0030995575 scopus 로고    scopus 로고
    • Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
    • Monteleone G, Biancone L, Marasco R et al. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 1997; 112:1169-1178.
    • (1997) Gastroenterology , vol.112 , pp. 1169-1178
    • Monteleone, G.1    Biancone, L.2    Marasco, R.3
  • 6
    • 0031057872 scopus 로고    scopus 로고
    • Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease
    • Parronchi P, Romagnani P, Annunziato F et al. Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. Am J Pathol 1997; 150:823-832.
    • (1997) Am J Pathol , vol.150 , pp. 823-832
    • Parronchi, P.1    Romagnani, P.2    Annunziato, F.3
  • 7
    • 0034671633 scopus 로고    scopus 로고
    • Up-regulation of the IL-12 receptor beta 2 chain in Crohn's disease
    • Parrello T, Monteleone G, Cucchiara S et al. Up-regulation of the IL-12 receptor beta 2 chain in Crohn's disease. J Immunol 2000; 165:7234-7239.
    • (2000) J Immunol , vol.165 , pp. 7234-7239
    • Parrello, T.1    Monteleone, G.2    Cucchiara, S.3
  • 8
    • 0033168120 scopus 로고    scopus 로고
    • Bioactive IL-18 expression is up-regulated in Crohn's disease
    • Monteleone G, Trapasso F, Parrello T et al. Bioactive IL-18 expression is up-regulated in Crohn's disease. J Immunol 1999; 163:143-147.
    • (1999) J Immunol , vol.163 , pp. 143-147
    • Monteleone, G.1    Trapasso, F.2    Parrello, T.3
  • 9
    • 0033152023 scopus 로고    scopus 로고
    • IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: Expression and localization in intestinal mucosal cells
    • Pizarro TT, Michie MH, Bentz M et al. IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: Expression and localization in intestinal mucosal cells. J Immunol 1999; 162:6829-6835.
    • (1999) J Immunol , vol.162 , pp. 6829-6835
    • Pizarro, T.T.1    Michie, M.H.2    Bentz, M.3
  • 10
    • 0036305450 scopus 로고    scopus 로고
    • T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
    • Avni O, Lee D, Macian F et al. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol 2002; 3:643-651.
    • (2002) Nat Immunol , vol.3 , pp. 643-651
    • Avni, O.1    Lee, D.2    Macian, F.3
  • 11
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs Th1 lineage commitment
    • Szabo SJ, Kim ST, Costa GL et al. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000; 100:655-669.
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1    Kim, S.T.2    Costa, G.L.3
  • 12
    • 0036301997 scopus 로고    scopus 로고
    • Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction
    • Mullen AC, Hutchins AS, High FA et al. Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction. Nat Immunol 2002; 3:652-658.
    • (2002) Nat Immunol , vol.3 , pp. 652-658
    • Mullen, A.C.1    Hutchins, A.S.2    High, F.A.3
  • 13
    • 0035997908 scopus 로고    scopus 로고
    • T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells
    • Afkarian M, Sedy JR, Yang J et al. T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells. Nat Immunol 2002; 3:549-557.
    • (2002) Nat Immunol , vol.3 , pp. 549-557
    • Afkarian, M.1    Sedy, J.R.2    Yang, J.3
  • 14
    • 0035910037 scopus 로고    scopus 로고
    • T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells
    • Lighvani AA, Frucht DM, Jankovic D et al. T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells. Proc Nad Acad Sci USA 2001; 98:15137-15142.
    • (2001) Proc Nad Acad Sci USA , vol.98 , pp. 15137-15142
    • Lighvani, A.A.1    Frucht, D.M.2    Jankovic, D.3
  • 15
    • 0037029649 scopus 로고    scopus 로고
    • The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
    • Neurath MF, Weigmann B, Finotto S et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J Exp Med 2002; 195:1129-1143.
    • (2002) J Exp Med , vol.195 , pp. 1129-1143
    • Neurath, M.F.1    Weigmann, B.2    Finotto, S.3
  • 16
    • 0037022008 scopus 로고    scopus 로고
    • Crohn's disease
    • Shanahan F. Crohn's disease. Lancet 2002; 359:62-69.
    • (2002) Lancet , vol.359 , pp. 62-69
    • Shanahan, F.1
  • 17
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
    • Duchmann R, Kaiser I, Hermann E et al. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol 1995; 102:448-455.
    • (1995) Clin Exp Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1    Kaiser, I.2    Hermann, E.3
  • 18
    • 0034040532 scopus 로고    scopus 로고
    • Chronic granulomatous disease. Report on a national registry of 368 patients
    • Winkelstein JA, Marino MC, Johnston Jr RB et al. Chronic granulomatous disease. Report on a national registry of 368 patients. Medicine (Baltimore) 2000; 79:155-169.
    • (2000) Medicine (Baltimore) , vol.79 , pp. 155-169
    • Winkelstein, J.A.1    Marino, M.C.2    Johnston Jr, R.B.3
  • 19
    • 0031966917 scopus 로고    scopus 로고
    • Treatment of enteritis in chronic granulomatous disease with granulocyte colony stimulating factor
    • Myrup B, Valerius NH, Mortensen PB. Treatment of enteritis in chronic granulomatous disease with granulocyte colony stimulating factor. Gut 1998; 42:127-130.
    • (1998) Gut , vol.42 , pp. 127-130
    • Myrup, B.1    Valerius, N.H.2    Mortensen, P.B.3
  • 20
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001; 411:603-606.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3
  • 21
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot JP, Chamaillard M, Zouali H et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411:599-603.
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1    Chamaillard, M.2    Zouali, H.3
  • 22
    • 18444385868 scopus 로고    scopus 로고
    • IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells
    • Pflanz S, Timans JC, Cheung J et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity 2002; 16:779-790.
    • (2002) Immunity , vol.16 , pp. 779-790
    • Pflanz, S.1    Timans, J.C.2    Cheung, J.3
  • 23
    • 0031879734 scopus 로고    scopus 로고
    • An interleukin 12-related cytokine is up-regulated in ulcerative colitis but not in Crohn's disease
    • Christ AD, Stevens AC, Koeppen H et al. An interleukin 12-related cytokine is up-regulated in ulcerative colitis but not in Crohn's disease. Gastroenterology 1998; 115:307-313.
    • (1998) Gastroenterology , vol.115 , pp. 307-313
    • Christ, A.D.1    Stevens, A.C.2    Koeppen, H.3
  • 24
    • 0034891647 scopus 로고    scopus 로고
    • The expression of IL-12 p40 and its homologue, Epstein-Barr virus-induced gene 3, in inflammatory bowel disease
    • Omata F, Birkenbach M, Matsuzaki S et al. The expression of IL-12 p40 and its homologue, Epstein-Barr virus-induced gene 3, in inflammatory bowel disease. Inflamm Bowel Dis 2001; 7:215-220.
    • (2001) Inflamm Bowel Dis , vol.7 , pp. 215-220
    • Omata, F.1    Birkenbach, M.2    Matsuzaki, S.3
  • 25
    • 0023485712 scopus 로고
    • Mucosal subclass distribution of immunoglobulin G-producing cells is different in ulcerative colitis and Crohn's disease of the colon
    • Kett K, Rognum TO, Brandtzaeg P. Mucosal subclass distribution of immunoglobulin G-producing cells is different in ulcerative colitis and Crohn's disease of the colon. Gastroenterology 1987; 93:919-924.
    • (1987) Gastroenterology , vol.93 , pp. 919-924
    • Kett, K.1    Rognum, T.O.2    Brandtzaeg, P.3
  • 26
    • 58849125667 scopus 로고    scopus 로고
    • Brandtzaeg P. The B cell system. Food Allergy & Intolerance. London: Bailliere Tindall, 1987; 118-155.
    • Brandtzaeg P. The B cell system. Food Allergy & Intolerance. London: Bailliere Tindall, 1987; 118-155.
  • 27
  • 28
    • 0026649732 scopus 로고
    • Surface epithelium related activation of complement differs in Crohn's disease and ulcerative colitis
    • Halstensen TS, Mollnes TE, Garred P et al. Surface epithelium related activation of complement differs in Crohn's disease and ulcerative colitis. Gut 1992; 33:902-908.
    • (1992) Gut , vol.33 , pp. 902-908
    • Halstensen, T.S.1    Mollnes, T.E.2    Garred, P.3
  • 29
    • 0025320911 scopus 로고
    • Epithelial deposition of immunoglobulin G1 and activated complement (C3b and terminal complement complex) in ulcerative colitis
    • Halstensen TS, Mollnes TE, Garred P et al. Epithelial deposition of immunoglobulin G1 and activated complement (C3b and terminal complement complex) in ulcerative colitis. Gastroenterology 1990; 98:1264-1271.
    • (1990) Gastroenterology , vol.98 , pp. 1264-1271
    • Halstensen, T.S.1    Mollnes, T.E.2    Garred, P.3
  • 30
    • 0027232053 scopus 로고
    • Epithelial deposits of immunoglobulin G1 and activated complement colocalise with the M(r) 40 kD putative autoantigen in ulcerative colitis
    • Halstensen TS, Das KM, Brandtzaeg P. Epithelial deposits of immunoglobulin G1 and activated complement colocalise with the M(r) 40 kD putative autoantigen in ulcerative colitis. Gut 1993; 34:650-657.
    • (1993) Gut , vol.34 , pp. 650-657
    • Halstensen, T.S.1    Das, K.M.2    Brandtzaeg, P.3
  • 31
    • 0014071475 scopus 로고
    • Autoantibodies in ulcerative colitis
    • McGiven AR, Chose T, Nairn RC. Autoantibodies in ulcerative colitis. Br Med J 1967; 2:19-23.
    • (1967) Br Med J , vol.2 , pp. 19-23
    • McGiven, A.R.1    Chose, T.2    Nairn, R.C.3
  • 32
    • 0015538855 scopus 로고
    • Fluorescent anti-colon and organ-specific antibodies in ulcerative colitis
    • Marcussen H, Nerup J. Fluorescent anti-colon and organ-specific antibodies in ulcerative colitis. Scand J Gastroenterol 1973; 8:9-15.
    • (1973) Scand J Gastroenterol , vol.8 , pp. 9-15
    • Marcussen, H.1    Nerup, J.2
  • 33
    • 0028216254 scopus 로고
    • Appendectomy protects against ulcerative colitis
    • Rutgeerts P, D'Haens G, Hiele M et al. Appendectomy protects against ulcerative colitis. Gastroenterology 1994; 106:1251-1253.
    • (1994) Gastroenterology , vol.106 , pp. 1251-1253
    • Rutgeerts, P.1    D'Haens, G.2    Hiele, M.3
  • 34
    • 0031136733 scopus 로고    scopus 로고
    • Appendectomy, mucosal immunity, and colitis
    • Shanahan F, O'Sullivan GC. Appendectomy, mucosal immunity, and colitis. Gastroenterology 1997; 112:1766-1767.
    • (1997) Gastroenterology , vol.112 , pp. 1766-1767
    • Shanahan, F.1    O'Sullivan, G.C.2
  • 35
    • 0033858932 scopus 로고    scopus 로고
    • A patient with improvement of ulcerative colitis after appendectomy
    • Okazaki K, Onodera H, Watanabe N et al. A patient with improvement of ulcerative colitis after appendectomy. Gastroenterology 2000; 119:502-506.
    • (2000) Gastroenterology , vol.119 , pp. 502-506
    • Okazaki, K.1    Onodera, H.2    Watanabe, N.3
  • 36
    • 0036896654 scopus 로고    scopus 로고
    • Effects of appendectomy on the course of ulcerative colitis
    • Cosnes J, Carbonnel F, Beaugerie L et al. Effects of appendectomy on the course of ulcerative colitis. Gut 2002; 51:803-807.
    • (2002) Gut , vol.51 , pp. 803-807
    • Cosnes, J.1    Carbonnel, F.2    Beaugerie, L.3
  • 37
    • 0031455902 scopus 로고    scopus 로고
    • Rabbit appendix: A site of development and selection of the B cell repertoire
    • Pospisil R, Mage RG. Rabbit appendix: A site of development and selection of the B cell repertoire. Curr Top Microbiol Immunol 1998; 229:59-70.
    • (1998) Curr Top Microbiol Immunol , vol.229 , pp. 59-70
    • Pospisil, R.1    Mage, R.G.2
  • 38
    • 0025969043 scopus 로고
    • Ileal Peyer's patch emigrants are predominantly B cells and travel to all lymphoid tissues in sheep
    • Reynolds JD, Kennedy L, Peppard J et al. Ileal Peyer's patch emigrants are predominantly B cells and travel to all lymphoid tissues in sheep. Eur J Immunol 1991; 21:283-289.
    • (1991) Eur J Immunol , vol.21 , pp. 283-289
    • Reynolds, J.D.1    Kennedy, L.2    Peppard, J.3
  • 39
    • 0036293999 scopus 로고    scopus 로고
    • Related IgA1 and IgG producing cells in blood and diseased mucosa in ulcerative colitis
    • Thoree VC, Golby SJ, Boursier L et al. Related IgA1 and IgG producing cells in blood and diseased mucosa in ulcerative colitis. Gut 2002; 51:44-50.
    • (2002) Gut , vol.51 , pp. 44-50
    • Thoree, V.C.1    Golby, S.J.2    Boursier, L.3
  • 40
    • 10844272960 scopus 로고    scopus 로고
    • van Deventer SJ. Small therapeutic molecules for the treatment of inflammatory bowel disease. Gut 2002; 50(Suppl 3):III47-III53.
    • van Deventer SJ. Small therapeutic molecules for the treatment of inflammatory bowel disease. Gut 2002; 50(Suppl 3):III47-III53.
  • 41
    • 0032063661 scopus 로고    scopus 로고
    • Proteolytic enzymes in inflammatory bowel disease
    • MacDonald TT, Pender SL. Proteolytic enzymes in inflammatory bowel disease. Inflamm Bowel Dis 1998; 4:157-164.
    • (1998) Inflamm Bowel Dis , vol.4 , pp. 157-164
    • MacDonald, T.T.1    Pender, S.L.2
  • 42
    • 0030041819 scopus 로고    scopus 로고
    • Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers
    • Saarialho-Kere UK, Vaalamo M, Puolakkainen P et al. Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers. Am J Pathol 1996; 148:519-526.
    • (1996) Am J Pathol , vol.148 , pp. 519-526
    • Saarialho-Kere, U.K.1    Vaalamo, M.2    Puolakkainen, P.3
  • 43
    • 0031898338 scopus 로고    scopus 로고
    • Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations
    • Vaalamo M, Karjalainen-Lindsberg ML, Puolakkainen P et al. Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations. Am J Pathol 1998; 152:1005-1014.
    • (1998) Am J Pathol , vol.152 , pp. 1005-1014
    • Vaalamo, M.1    Karjalainen-Lindsberg, M.L.2    Puolakkainen, P.3
  • 44
    • 0031714443 scopus 로고    scopus 로고
    • Suppression of T cell-mediated injury in human gut by interleukin 10: Role of matrix metalloproteinases
    • Pender SL, Breese EJ, Gunther U et al. Suppression of T cell-mediated injury in human gut by interleukin 10: Role of matrix metalloproteinases. Gastroenterology 1998; 115:573-583.
    • (1998) Gastroenterology , vol.115 , pp. 573-583
    • Pender, S.L.1    Breese, E.J.2    Gunther, U.3
  • 45
    • 0033916643 scopus 로고    scopus 로고
    • Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease
    • Heuschkel RB, MacDonald TT, Monteleone G et al. Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease. Gut 2000; 47:57-62.
    • (2000) Gut , vol.47 , pp. 57-62
    • Heuschkel, R.B.1    MacDonald, T.T.2    Monteleone, G.3
  • 46
    • 0031568392 scopus 로고    scopus 로고
    • A major role for matrix metalloproteinases in T cell injury in the gut
    • Pender SL, Tickle SP, Docherty AJ et al. A major role for matrix metalloproteinases in T cell injury in the gut. J Immunol 1997; 158:1582-1590.
    • (1997) J Immunol , vol.158 , pp. 1582-1590
    • Pender, S.L.1    Tickle, S.P.2    Docherty, A.J.3
  • 47
    • 0032718351 scopus 로고    scopus 로고
    • Enhancing lamina propria Th1 cell responses with interleukin 12 produces severe tissue injury
    • Monteleone G, MacDonald TT, Wathen NC et al. Enhancing lamina propria Th1 cell responses with interleukin 12 produces severe tissue injury. Gastroenterology 1999; 117:1069-1077.
    • (1999) Gastroenterology , vol.117 , pp. 1069-1077
    • Monteleone, G.1    MacDonald, T.T.2    Wathen, N.C.3
  • 48
    • 0032211804 scopus 로고    scopus 로고
    • ECM signalling: Orchestrating cell behaviour and misbehaviour
    • Lukashev ME, Werb Z. ECM signalling: Orchestrating cell behaviour and misbehaviour. Trends Cell Biol 1998; 437-41.
    • (1998) Trends Cell Biol , pp. 437-441
    • Lukashev, M.E.1    Werb, Z.2
  • 49
    • 0030958072 scopus 로고    scopus 로고
    • Degradation of decorin by matrix metalloproteinases: Identification of the cleavage sites, kinetic analyses and transforming growth factor-beta1 release
    • Imai K, Hiramatsu A, Fukushima D et al. Degradation of decorin by matrix metalloproteinases: Identification of the cleavage sites, kinetic analyses and transforming growth factor-beta1 release. Biochem J 1997; 322:809-14.
    • (1997) Biochem J , vol.322 , pp. 809-814
    • Imai, K.1    Hiramatsu, A.2    Fukushima, D.3
  • 50
    • 0040945730 scopus 로고    scopus 로고
    • Differential effects of transforming growth factor-beta on the expression of collagenase-1 and collagenase-3 in human fibroblasts
    • Uria JA, Jimenez MG, Balbin M et al. Differential effects of transforming growth factor-beta on the expression of collagenase-1 and collagenase-3 in human fibroblasts. J Biol Chem 1998; 273:9769-9777.
    • (1998) J Biol Chem , vol.273 , pp. 9769-9777
    • Uria, J.A.1    Jimenez, M.G.2    Balbin, M.3
  • 51
    • 0034894059 scopus 로고    scopus 로고
    • Blocking Smad7 restores TGFβ1 signalling in chronic inflammatory bowel disease
    • Monteleone G, Kumberova A, Croft NM et al. Blocking Smad7 restores TGFβ1 signalling in chronic inflammatory bowel disease. J Clin Invest 2001; 108:601-608.
    • (2001) J Clin Invest , vol.108 , pp. 601-608
    • Monteleone, G.1    Kumberova, A.2    Croft, N.M.3
  • 52
    • 0031426654 scopus 로고    scopus 로고
    • Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells
    • Lochter A, Galosy S, Muschler J et al. Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J Cell Biol 1997; 139:1861-72.
    • (1997) J Cell Biol , vol.139 , pp. 1861-1872
    • Lochter, A.1    Galosy, S.2    Muschler, J.3
  • 53
    • 0035147313 scopus 로고    scopus 로고
    • Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1
    • Noe V, Fingleton B, Jacobs K et al. Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1. J Cell Sci 2001; 114:111-118.
    • (2001) J Cell Sci , vol.114 , pp. 111-118
    • Noe, V.1    Fingleton, B.2    Jacobs, K.3
  • 54
    • 0029558476 scopus 로고
    • E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers
    • Berx G, Cleton-Jansen AM, Nollet F et al. E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. EMBO J 1995; 14:6107-15.
    • (1995) EMBO J , vol.14 , pp. 6107-6115
    • Berx, G.1    Cleton-Jansen, A.M.2    Nollet, F.3
  • 55
    • 0033525037 scopus 로고    scopus 로고
    • Metalloprotease-disintegrin MDC9: Intracellular maturation and catalytic activity
    • Roghani M, Becherer JD, Moss ML et al. Metalloprotease-disintegrin MDC9: Intracellular maturation and catalytic activity. J Biol Chem 1999; 274:3531-40.
    • (1999) J Biol Chem , vol.274 , pp. 3531-3540
    • Roghani, M.1    Becherer, J.D.2    Moss, M.L.3
  • 56
    • 0030596456 scopus 로고    scopus 로고
    • Degradation of interleukin 1β by matrix metalloproteinases
    • Ito A, Mukaiyama A, Itoh Y et al. Degradation of interleukin 1β by matrix metalloproteinases. J Biol Chem 1996; 271:14657-60.
    • (1996) J Biol Chem , vol.271 , pp. 14657-14660
    • Ito, A.1    Mukaiyama, A.2    Itoh, Y.3
  • 57
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
    • Shull MM, Ormsby I, Kier AB et al. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 1992; 359:693-699.
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1    Ormsby, I.2    Kier, A.B.3
  • 58
    • 0027531528 scopus 로고
    • Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death
    • Kulkarni AB, Huh CG, Becker D et al. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 1993; 90:770-774.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 770-774
    • Kulkarni, A.B.1    Huh, C.G.2    Becker, D.3
  • 59
    • 0029913624 scopus 로고    scopus 로고
    • Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease
    • Babyatsky MW, Rossiter G, Podolsky DK. Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease. Gastroenterology 1996; 110:975-984.
    • (1996) Gastroenterology , vol.110 , pp. 975-984
    • Babyatsky, M.W.1    Rossiter, G.2    Podolsky, D.K.3
  • 60
    • 0037204990 scopus 로고    scopus 로고
    • Signal transduction by the TGF-beta superfamily
    • Attisano L, Wrana JL. Signal transduction by the TGF-beta superfamily. Science 2002; 296:1646-1647.
    • (2002) Science , vol.296 , pp. 1646-1647
    • Attisano, L.1    Wrana, J.L.2
  • 61
    • 0035694910 scopus 로고    scopus 로고
    • Smad regulation in TGF-beta signal transduction
    • Moustakas A, Souchelnytskyi S, Heldin CH. Smad regulation in TGF-beta signal transduction. J Cell Sci 2001; 114:4359-4369.
    • (2001) J Cell Sci , vol.114 , pp. 4359-4369
    • Moustakas, A.1    Souchelnytskyi, S.2    Heldin, C.H.3
  • 62
    • 1042266673 scopus 로고    scopus 로고
    • A failure of transforming growth factor-beta1 negative regulation maintains sustained NF-kappa B activation in gut inflammation
    • Monteleone G, Mann J, Monteleone I et al. A failure of transforming growth factor-beta1 negative regulation maintains sustained NF-kappa B activation in gut inflammation. J Biol Chem. 2004; 279:3925-3932.
    • (2004) J Biol Chem , vol.279 , pp. 3925-3932
    • Monteleone, G.1    Mann, J.2    Monteleone, I.3
  • 63
    • 58849090828 scopus 로고    scopus 로고
    • Microscopic colistis
    • Tahkalidis P et al. Microscopic colistis. J Castro Hepatol 17:236-248.
    • J Castro Hepatol , vol.17 , pp. 236-248
    • Tahkalidis, P.1
  • 64
    • 0024498128 scopus 로고
    • Lymphocytic ("microscopic") colitis: A comparative histopathologic study with particular reference to collagenous colitis
    • Lazenby AJ, Yardley JH, Giardiello FM et al. Lymphocytic ("microscopic") colitis: A comparative histopathologic study with particular reference to collagenous colitis. Hum Pathol 1989; 20:18-28.
    • (1989) Hum Pathol , vol.20 , pp. 18-28
    • Lazenby, A.J.1    Yardley, J.H.2    Giardiello, F.M.3
  • 65
    • 0029932174 scopus 로고    scopus 로고
    • Lymphocytic and collagenous colitis: An immunohistochemical study
    • Mosnier JF, Larvol L, Barge J et al. Lymphocytic and collagenous colitis: An immunohistochemical study. Am J Gastroenterol 1996; 91:709-713.
    • (1996) Am J Gastroenterol , vol.91 , pp. 709-713
    • Mosnier, J.F.1    Larvol, L.2    Barge, J.3
  • 66
    • 0038729744 scopus 로고    scopus 로고
    • Fibrogenesis and fibrolysis in collagenous colitis. Patterns of procollagen types I and IV, matrix-metalloproteinase-1 and -13, and TIMP-1 gene expression
    • Gunther U, Schuppan D, Bauer M et al. Fibrogenesis and fibrolysis in collagenous colitis. Patterns of procollagen types I and IV, matrix-metalloproteinase-1 and -13, and TIMP-1 gene expression. Am J Pathol 1999; 155:493-503.
    • (1999) Am J Pathol , vol.155 , pp. 493-503
    • Gunther, U.1    Schuppan, D.2    Bauer, M.3
  • 67
    • 0036789201 scopus 로고    scopus 로고
    • Budesonide treatment for collagenous colitis: A randomized, double-bhnd, placebo-controlled, multicenter trial
    • Miehlke S, Heymer P, Bethke B et al. Budesonide treatment for collagenous colitis: A randomized, double-bhnd, placebo-controlled, multicenter trial. Gastroenterology 2002; 123:978-984.
    • (2002) Gastroenterology , vol.123 , pp. 978-984
    • Miehlke, S.1    Heymer, P.2    Bethke, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.