Rabbit appendix: A site of development and selection of the B cell repertoire

Current Topics in Microbiology and Immunology

Volumn 229, Issue , 1997, Pages 59-70

  Pospisil, R ^a   Mage, R G ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN ANTIBODY REACTION; APPENDIX; B LYMPHOCYTE DIFFERENTIATION; GENE REARRANGEMENT; GERMINAL CENTER; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVIEW; SOMATIC MUTATION;

ANIMALS; APPENDIX; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL DIVISION; GERMINAL CENTER; HUMANS; RABBITS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0031455902     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review

References (7)

1. H genes closest to the joining region. Proc Natl Acad Sci USA 87:5444-5448
2. Ha allotype gene that is deleted in Alicia mutants; somatic hypermutation/conversion may play a major role in generating the heterogeneity of rabbit heavy chain variable region sequences. Eur J Immunol 21:411-417
3. Tiegs SL, Russell DM, Nemazee D (1993) Receptor editing in self-reactive bone marrow B cells. J Exp Med 177:1009-1020
4. Tlaskalová-Hogenová H, Stepánková R (1980) Development of antibody formation in germ-free and conventionally reared rabbits: the role of intestinal lymphoid tissue in antibody formation to E. coli antigens. Folia Biol 26:81-93
5. Weinstein PD, Mage RG, Anderson AO (1994a) The appendix functions as a mammalian bursal equivalent in the developing rabbit. In: Heinen E (ed) Proceedings of the 11th International Conference on Lymphoid Tissues and Germinal Centers. Plenum, New York, pp 249-253
6. H diversification by gene conversion-like and hypermutation mechanisms. Immunity 1:647-659
7. Zouali M (1995) B-cell superantigens: implications for selection of the human antibody repertoire. Immunol Today 16:399-405