-
1
-
-
0025875022
-
Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells
-
SF Wolf PA Temple M Kobayashi D Young M Dicig L Lowe R Dzialo L Fitz C Ferenz RM Hewick K Kelleher SH Hermann SC Clark L Azzoni SH Chan G Trinchieri B. Perussia Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells J Immunol 146 1991 3074 3082
-
(1991)
J Immunol
, vol.146
, pp. 3074-3082
-
-
Wolf, SF1
Temple, PA2
Kobayashi, M3
Young, D4
Dicig, M5
Lowe, L6
Dzialo, R7
Fitz, L8
Ferenz, C9
Hewick, RM10
Kelleher, K11
Hermann, SH12
Clark, SC13
Azzoni, L14
Chan, SH15
Trinchieri, G16
Perussia, B.17
-
2
-
-
0028043326
-
Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
-
G. Trinchieri Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes Blood 84 1994 4006 4027
-
(1994)
Blood
, vol.84
, pp. 4006-4027
-
-
Trinchieri, G.1
-
3
-
-
16044363695
-
IL-12–deficient mice are defective in IFNγ production and type 1 cytokine responses
-
J Magram SE Connaughton RR Warrier DM Carvajal C-Y Wu J Ferrante C Stewart U Sarmiento DA Faherty MK Gately IL-12–deficient mice are defective in IFNγ production and type 1 cytokine responses Immunity 4 1996 471 481
-
(1996)
Immunity
, vol.4
, pp. 471-481
-
-
Magram, J1
Connaughton, SE2
Warrier, RR3
Carvajal, DM4
Wu, C-Y5
Ferrante, J6
Stewart, C7
Sarmiento, U8
Faherty, DA9
Gately, MK10
-
4
-
-
0027491655
-
Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming
-
+ T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming Proc Natl Acad Sci USA 90 1993 10188 10192
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10188-10192
-
-
Seder, RA1
Gazzinelli, R2
Sher, A3
Paul, WE4
-
5
-
-
0028926524
-
Interleukin 12 aministration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice
-
S Trembleau G Penna E Bosi A Mortara MK Gately L. Adorini Interleukin 12 aministration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice J Exp Med 181 1995 817 821
-
(1995)
J Exp Med
, vol.181
, pp. 817-821
-
-
Trembleau, S1
Penna, G2
Bosi, E3
Mortara, A4
Gately, MK5
Adorini, L.6
-
6
-
-
0028845730
-
Cloning of a new cytokine that induces IFN-γ production by T cells
-
H Okamura H Tsutsui H Komatsu T Yutsuso A Hakura T Tanimoto K Torigoe T Okura Y Nukada K Hattori K Akita M Namba F Tanabe K Konishi S Fukuda M Kurimoto Cloning of a new cytokine that induces IFN-γ production by T cells Nature 378 1995 88 91
-
(1995)
Nature
, vol.378
, pp. 88-91
-
-
Okamura, H1
Tsutsui, H2
Komatsu, H3
Yutsuso, T4
Hakura, A5
Tanimoto, T6
Torigoe, K7
Okura, T8
Nukada, Y9
Hattori, K10
Akita, K11
Namba, M12
Tanabe, F13
Konishi, K14
Fukuda, S15
Kurimoto, M16
-
7
-
-
0031568526
-
IFN-γ–inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12
-
K Kohno J Kataoka T Ohtsuki Y Suemoto I Okamoto M Usui M Ikeda M Kurimoto IFN-γ–inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12 J Immunol 158 1997 1541 1550
-
(1997)
J Immunol
, vol.158
, pp. 1541-1550
-
-
Kohno, K1
Kataoka, J2
Ohtsuki, T3
Suemoto, Y4
Okamoto, I5
Usui, M6
Ikeda, M7
Kurimoto, M8
-
8
-
-
0031230444
-
A mechanism underlying synergy between IL-12 and IFN-gamma–inducing factor in enhanced production of IFN-gamma
-
HJ Ahn S Maruo M Tomura J Mu T Hamaoka K Nakanishi S Clark M Kurimoto O Okamura H Fujiwara A mechanism underlying synergy between IL-12 and IFN-gamma–inducing factor in enhanced production of IFN-gamma J Immunol 159 1997 2125 2131
-
(1997)
J Immunol
, vol.159
, pp. 2125-2131
-
-
Ahn, HJ1
Maruo, S2
Tomura, M3
Mu, J4
Hamaoka, T5
Nakanishi, K6
Clark, S7
Kurimoto, M8
Okamura, O9
Fujiwara, H10
-
9
-
-
0033563026
-
IL-18 and CD28 use distinct molecular mechanisms to enhance NK cell production of IL-12–induced IFN-γ
-
W Walker M Aste-Amezaga RA Kastelein G Trinchieri CA Hunter IL-18 and CD28 use distinct molecular mechanisms to enhance NK cell production of IL-12–induced IFN-γ J Immunol 162 1999 5894 5901
-
(1999)
J Immunol
, vol.162
, pp. 5894-5901
-
-
Walker, W1
Aste-Amezaga, M2
Kastelein, RA3
Trinchieri, G4
Hunter, CA5
-
10
-
-
0031781603
-
Inflammatory bowel disease: etiology and pathogenesis
-
C. Fiocchi Inflammatory bowel disease: etiology and pathogenesis Gastroenterology 115 1998 182 205
-
(1998)
Gastroenterology
, vol.115
, pp. 182-205
-
-
Fiocchi, C.1
-
11
-
-
0027441514
-
Interleukin-2 and interferon-γ secreting T cells in normal and diseased human intestinal mucosa
-
E Breese CP Braegger CJ Corrigan JA Walker-Smith TT MacDonald Interleukin-2 and interferon-γ secreting T cells in normal and diseased human intestinal mucosa Immunology 78 1993 127 131
-
(1993)
Immunology
, vol.78
, pp. 127-131
-
-
Breese, E1
Braegger, CP2
Corrigan, CJ3
Walker-Smith, JA4
MacDonald, TT5
-
12
-
-
0025804331
-
Spontaneous release of interferon gamma by intestinal lamina propria lymphocytes in Crohn's disease. Kinetics of in vitro response to interferon gamma inducers
-
S Fais MR Capobianchi F Pallone P Di Marco M Boirivant F Dianzani A. Torsoli Spontaneous release of interferon gamma by intestinal lamina propria lymphocytes in Crohn's disease. Kinetics of in vitro response to interferon gamma inducers Gut 32 1991 403 407
-
(1991)
Gut
, vol.32
, pp. 403-407
-
-
Fais, S1
Capobianchi, MR2
Pallone, F3
Di Marco, P4
Boirivant, M5
Dianzani, F6
Torsoli, A.7
-
13
-
-
0030209985
-
Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
-
+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5 J Immunol 157 1996 1261 1270
-
(1996)
J Immunol
, vol.157
, pp. 1261-1270
-
-
Fuss, IJ1
Neurath, M2
Boirivant, M3
Klein, JS4
de la Motte, C5
Strong, SA6
Fiocchi, C7
Strober, W8
-
14
-
-
0030995575
-
Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
-
G Monteleone L Biancone R Marasco G Morrone O Marasco F Luzza F. Pallone Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells Gastroenterology 112 1997 1169 1178
-
(1997)
Gastroenterology
, vol.112
, pp. 1169-1178
-
-
Monteleone, G1
Biancone, L2
Marasco, R3
Morrone, G4
Marasco, O5
Luzza, F6
Pallone, F.7
-
15
-
-
0031057872
-
Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease
-
P Parronchi P Romagnani F Annunziato F Sampognaro A Becchio L Giannarini E Maggi C Pupilli F Tonelli S. Romagnani Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease Am J Pathol 150 1997 823 832
-
(1997)
Am J Pathol
, vol.150
, pp. 823-832
-
-
Parronchi, P1
Romagnani, P2
Annunziato, F3
Sampognaro, F4
Becchio, A5
Giannarini, L6
Maggi, E7
Pupilli, C8
Tonelli, F9
Romagnani, S.10
-
16
-
-
0031888743
-
Interleukin-12 expression is focally enhanced in the gastric mucosa of pediatric patients with Crohn' s disease
-
D Berrebi M Besnard G Fromont-Hankard R Paris JF Mougenot P De Lagausie D Emilie JP Cezard J Navarro M. Peuchmaur Interleukin-12 expression is focally enhanced in the gastric mucosa of pediatric patients with Crohn' s disease Am J Pathol 152 1998 667 672
-
(1998)
Am J Pathol
, vol.152
, pp. 667-672
-
-
Berrebi, D1
Besnard, M2
Fromont-Hankard, G3
Paris, R4
Mougenot, JF5
De Lagausie, P6
Emilie, D7
Cezard, JP8
Navarro, J9
Peuchmaur, M.10
-
17
-
-
0031743056
-
Response of human intestinal lamina propria T lymphocytes to interleukin 12: additive effects of interleukin 15 and 7
-
G Monteleone T Parrello F Luzza F. Pallone Response of human intestinal lamina propria T lymphocytes to interleukin 12: additive effects of interleukin 15 and 7 Gut 43 1998 620 628
-
(1998)
Gut
, vol.43
, pp. 620-628
-
-
Monteleone, G1
Parrello, T2
Luzza, F3
Pallone, F.4
-
18
-
-
0028861975
-
Antibodies to interleukin 12 abrogate established experimental colitis in mice
-
MF Neurath I Fuss BL Kelsall E Stuber W. Strober Antibodies to interleukin 12 abrogate established experimental colitis in mice J Exp Med 182 1995 1281 1290
-
(1995)
J Exp Med
, vol.182
, pp. 1281-1290
-
-
Neurath, MF1
Fuss, I2
Kelsall, BL3
Stuber, E4
Strober, W.5
-
19
-
-
0033558364
-
Chronic intestinal inflammation in STAT-4 transgenic mice: characterization of disease and adoptive transfer by TNF-plus IFN-gamma–producing CD4+ T cells that respond to bacterial antigens
-
+ T cells that respond to bacterial antigens J Immunol 162 1999 1884 1888
-
(1999)
J Immunol
, vol.162
, pp. 1884-1888
-
-
Wirtz, S1
Finotto, S2
Kanzler, S3
Lohse, AW4
Blessing, M5
Lehr, HA6
Galle, PR7
Neurath, MF8
-
20
-
-
0032550312
-
T cell–mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells
-
SJ Simpson S Shah M Comiskey YP de Jong B Wang E Mizoguchi AK Bhan C Terhorst T cell–mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells J Exp Med 187 1998 1225 1234
-
(1998)
J Exp Med
, vol.187
, pp. 1225-1234
-
-
Simpson, SJ1
Shah, S2
Comiskey, M3
de Jong, YP4
Wang, B5
Mizoguchi, E6
Bhan, AK7
Terhorst, C8
-
21
-
-
0033152023
-
IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells
-
TT Pizarro MH Michie M Bentz J Woraratanadharm MF Smith E Foley CA Moskaluk SJ Bickston F. Cominelli IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells J Immunol 162 1999 6829 6835
-
(1999)
J Immunol
, vol.162
, pp. 6829-6835
-
-
Pizarro, TT1
Michie, MH2
Bentz, M3
Woraratanadharm, J4
Smith, MF5
Foley, E6
Moskaluk, CA7
Bickston, SJ8
Cominelli, F.9
-
22
-
-
0033168120
-
Bioactive interleukin-18 expression is up-regulated in Crohn's disease
-
G Monteleone F Trapasso T Parrello L Biancone A Stella R Iuliano F Luzza A Fusco F. Pallone Bioactive interleukin-18 expression is up-regulated in Crohn's disease J Immunol 163 1999 143 147
-
(1999)
J Immunol
, vol.163
, pp. 143-147
-
-
Monteleone, G1
Trapasso, F2
Parrello, T3
Biancone, L4
Stella, A5
Iuliano, R6
Luzza, F7
Fusco, A8
Pallone, F.9
-
23
-
-
0023925510
-
Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine
-
TT MacDonald J. Spencer Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine J Exp Med 167 1988 1341 1349
-
(1988)
J Exp Med
, vol.167
, pp. 1341-1349
-
-
MacDonald, TT1
Spencer, J.2
-
24
-
-
0027292917
-
T-cell activation can induce either mucosal destruction or adaptation in cultured human fetal small intestine
-
P Lionetti E Breese CP Braegger SH Murch J Taylor TT. MacDonald T-cell activation can induce either mucosal destruction or adaptation in cultured human fetal small intestine Gastroenterology 105 1993 373 381
-
(1993)
Gastroenterology
, vol.105
, pp. 373-381
-
-
Lionetti, P1
Breese, E2
Braegger, CP3
Murch, SH4
Taylor, J5
MacDonald, TT.6
-
26
-
-
0029814859
-
Proteolytic degradation of intestinal mucosal extracellular matrix after lamina propria T cell activation
-
SLF Pender P Lionetti SH Murch N Wathan TT. MacDonald Proteolytic degradation of intestinal mucosal extracellular matrix after lamina propria T cell activation Gut 39 1996 284 290
-
(1996)
Gut
, vol.39
, pp. 284-290
-
-
Pender, SLF1
Lionetti, P2
Murch, SH3
Wathan, N4
MacDonald, TT.5
-
27
-
-
0025847582
-
Matrix metalloproteinases and their inhibitors in connective tissue remodelling
-
JF. Woessner Matrix metalloproteinases and their inhibitors in connective tissue remodelling FASEB J 5 1991 2145 2154
-
(1991)
FASEB J
, vol.5
, pp. 2145-2154
-
-
Woessner, JF.1
-
28
-
-
0026896029
-
The matrix-degrading metalloproteinases
-
LM Matrisian The matrix-degrading metalloproteinases Bioassays 14 1992 455 463
-
(1992)
Bioassays
, vol.14
, pp. 455-463
-
-
Matrisian, LM1
-
29
-
-
0032532362
-
Interactions between stromal cell-derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia
-
M Bajaj-Elliott R Poulsom SLF Pender NC Wathen TT. MacDonald Interactions between stromal cell-derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia J Clin Invest 102 1998 1473 1480
-
(1998)
J Clin Invest
, vol.102
, pp. 1473-1480
-
-
Bajaj-Elliott, M1
Poulsom, R2
Pender, SLF3
Wathen, NC4
MacDonald, TT.5
-
30
-
-
0032522666
-
A p55 TNF receptor immunoadhesin prevents T cell–mediated intestinal injury by inhibiting matrix metalloproteinase production
-
SLF Pender JME Fell SM Chamow A Ashkenazi TT MacDonald A p55 TNF receptor immunoadhesin prevents T cell–mediated intestinal injury by inhibiting matrix metalloproteinase production J Immunol 160 1998 4098 4103
-
(1998)
J Immunol
, vol.160
, pp. 4098-4103
-
-
Pender, SLF1
Fell, JME2
Chamow, SM3
Ashkenazi, A4
MacDonald, TT5
-
31
-
-
0004314201
-
Immunocytochemistry of lymphoreticular tumours
-
PG Isaacson DH. Wright Immunocytochemistry of lymphoreticular tumours JM Polak S van Noorden Immunocytochemistry: practical applications in pathology and biology 1983 Wright Bristol, England 249
-
(1983)
, pp. 249
-
-
Isaacson, PG1
Wright, DH.2
-
32
-
-
0028864991
-
A distinct array of pro-inflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
-
HC Jung L Eckmann SK Yang A Panja J Fierer E Morzycka-Wroblewska MF. Kagnoff A distinct array of pro-inflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion J Clin Invest 95 1995 55 65
-
(1995)
J Clin Invest
, vol.95
, pp. 55-65
-
-
Jung, HC1
Eckmann, L2
Yang, SK3
Panja, A4
Fierer, J5
Morzycka-Wroblewska, E6
Kagnoff, MF.7
-
33
-
-
13344295075
-
Competitive RNA templates for detection and quantification of growth factors, cytokines, extracellular matrix components and matrix metalloproteinases by RT-PCR
-
RW Tarnuzzer SP Macauley WG Farmerie S Caballero MR Ghassemifar JT Anderson CP Robinson MB Grant MG Humphreys-Beher L Franzen AB Peck GS. Schultz Competitive RNA templates for detection and quantification of growth factors, cytokines, extracellular matrix components and matrix metalloproteinases by RT-PCR Biotechniques 20 1996 670 674
-
(1996)
Biotechniques
, vol.20
, pp. 670-674
-
-
Tarnuzzer, RW1
Macauley, SP2
Farmerie, WG3
Caballero, S4
Ghassemifar, MR5
Anderson, JT6
Robinson, CP7
Grant, MB8
Humphreys-Beher, MG9
Franzen, L10
Peck, AB11
Schultz, GS.12
-
34
-
-
0030445948
-
A functional interleukin 12 receptor complex is composed of two β-type cytokine receptor subunits
-
DH Presky H Yang LJ Minetti AO Chua N Nabavi C-Y Wu MK Gately U Gubler A functional interleukin 12 receptor complex is composed of two β-type cytokine receptor subunits Proc Natl Acad Sci USA 93 1996 14002 14007
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14002-14007
-
-
Presky, DH1
Yang, H2
Minetti, LJ3
Chua, AO4
Nabavi, N5
Wu, C-Y6
Gately, MK7
Gubler, U8
-
35
-
-
8044250881
-
Regulation of the interleukin (IL)-12Rβ2 subunit expression in developing T helper 1 (TH1) and Th2 cells
-
SJ Szabo AS Dighe U Gubler KM Murphy Regulation of the interleukin (IL)-12Rβ2 subunit expression in developing T helper 1 (TH1) and Th2 cells J Exp Med 185 1997 817 824
-
(1997)
J Exp Med
, vol.185
, pp. 817-824
-
-
Szabo, SJ1
Dighe, AS2
Gubler, U3
Murphy, KM4
-
36
-
-
0033560023
-
Regulation of interleukin (IL)-12 receptor beta 2 subunit expression by endogenous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells
-
JT Chang EM Shevach BM. Segal Regulation of interleukin (IL)-12 receptor beta 2 subunit expression by endogenous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells J Exp Med 189 1999 969 978
-
(1999)
J Exp Med
, vol.189
, pp. 969-978
-
-
Chang, JT1
Shevach, EM2
Segal, BM.3
-
37
-
-
0030851728
-
Purification and characterization of the human interleukin-18 receptor
-
K Torigoe S Ushino T Okura S Kobayashi M Taniai T Kunikata T Murakami O Sanou H Kojima M Fujii T Ohta M Ikeda H Ikegami M. Kurimoto Purification and characterization of the human interleukin-18 receptor J Biol Chem 272 1997 25737 25742
-
(1997)
J Biol Chem
, vol.272
, pp. 25737-25742
-
-
Torigoe, K1
Ushino, S2
Okura, T3
Kobayashi, S4
Taniai, M5
Kunikata, T6
Murakami, T7
Sanou, O8
Kojima, H9
Fujii, M10
Ohta, T11
Ikeda, M12
Ikegami, H13
Kurimoto, M.14
-
41
-
-
0020358297
-
Localization of type IV collagen, laminin, heparansulfate proteoglycan and fibronectin to the basal lamina of basement membranes
-
GW Laurie CP Leblond GR. Martin Localization of type IV collagen, laminin, heparansulfate proteoglycan and fibronectin to the basal lamina of basement membranes J Cell Biol 95 1982 340 344
-
(1982)
J Cell Biol
, vol.95
, pp. 340-344
-
-
Laurie, GW1
Leblond, CP2
Martin, GR.3
-
42
-
-
0025174982
-
Basement membrane components are potent promoters of rat intestinal epithelial cell differentiation in vitro
-
U Hann A Stallmach EG Hahn EO. Riecken Basement membrane components are potent promoters of rat intestinal epithelial cell differentiation in vitro Gastroenterology 98 1990 322 335
-
(1990)
Gastroenterology
, vol.98
, pp. 322-335
-
-
Hann, U1
Stallmach, A2
Hahn, EG3
Riecken, EO.4
-
44
-
-
0031898338
-
Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP13), macrophage metalloelastase (MMP12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations
-
M Vaalamo ML Karjalainen-Lindsberg P Puolakkainen J Kere U. Saarialho-Kere Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP13), macrophage metalloelastase (MMP12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations Am J Pathol 152 1998 1005 1014
-
(1998)
Am J Pathol
, vol.152
, pp. 1005-1014
-
-
Vaalamo, M1
Karjalainen-Lindsberg, ML2
Puolakkainen, P3
Kere, J4
Saarialho-Kere, U.5
-
45
-
-
0030041819
-
Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers
-
U Saarialho-Kere M Vaalamo P Puolakkainen K Airola WC Parks ML. Karjalainen-Lindsberg Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers Am J Pathol 148 1996 519 526
-
(1996)
Am J Pathol
, vol.148
, pp. 519-526
-
-
Saarialho-Kere, U1
Vaalamo, M2
Puolakkainen, P3
Airola, K4
Parks, WC5
Karjalainen-Lindsberg, ML.6
|