메뉴 건너뛰기




Volumn 115, Issue 3, 1998, Pages 573-583

Suppression of T cell-mediated injury in human gut by interleukin 10: Role of matrix metalloproteinases

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; CD3 ANTIGEN; COLLAGENASE; CYTOKINE; GAMMA INTERFERON; GELATINASE A; GELATINASE B; GLYCOSAMINOGLYCAN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; MATRIX METALLOPROTEINASE; MESSENGER RNA; POKEWEED MITOGEN; RECOMBINANT INTERLEUKIN 10; STAPHYLOCOCCUS ENTEROTOXIN B; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0031714443     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(98)70136-2     Document Type: Article
Times cited : (73)

References (65)
  • 4
    • 0026094306 scopus 로고
    • Interleukin-10 inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes
    • R de Waal Malefyt J Abrams B Bennett CG Figdor JE. de Vries Interleukin-10 inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes J Exp Med 174 1991 1209 1220
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • de Waal Malefyt, R1    Abrams, J2    Bennett, B3    Figdor, CG4    de Vries, JE.5
  • 6
    • 0026530464 scopus 로고
    • IL-10, T lymphocyte inhibitor of human blood cell production of IL-1 and tumor necrosis factor
    • P Ralph I Nakoinz A Sampson-Johannes S Fong D Lowe HY Min L. Lin IL-10, T lymphocyte inhibitor of human blood cell production of IL-1 and tumor necrosis factor J Immunol 148 1992 808 814
    • (1992) J Immunol , vol.148 , pp. 808-814
    • Ralph, P1    Nakoinz, I2    Sampson-Johannes, A3    Fong, S4    Lowe, D5    Min, HY6    Lin, L.7
  • 7
    • 0027521572 scopus 로고
    • Interleukin-10–deficient mice develop chronic enterocolitis
    • R Kuhn J Lohler D Rennick K Rajewsky W. Muller Interleukin-10–deficient mice develop chronic enterocolitis Cell 75 1993 263 274
    • (1993) Cell , vol.75 , pp. 263-274
    • Kuhn, R1    Lohler, J2    Rennick, D3    Rajewsky, K4    Muller, W.5
  • 9
    • 0029028515 scopus 로고
    • Circulating anti-inflammatory cytokine IL-10 in patients with inflammatory bowel disease (IBD)
    • T Kucharzik R Stoll N Lugering W. Domschke Circulating anti-inflammatory cytokine IL-10 in patients with inflammatory bowel disease (IBD) Clin Exp Immunol 100 1995 452 456
    • (1995) Clin Exp Immunol , vol.100 , pp. 452-456
    • Kucharzik, T1    Stoll, R2    Lugering, N3    Domschke, W.4
  • 10
    • 0028907439 scopus 로고
    • Immunoregulatory role of interleukin 10 in patients with inflammatory bowel disease
    • S Schreiber T Heinig HG Thiele A. Raedler Immunoregulatory role of interleukin 10 in patients with inflammatory bowel disease Gastroenterology 108 1995 1434 1444
    • (1995) Gastroenterology , vol.108 , pp. 1434-1444
    • Schreiber, S1    Heinig, T2    Thiele, HG3    Raedler, A.4
  • 11
    • 0029130042 scopus 로고
    • Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR)
    • M Niessner BA. Volk Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR) Clin Exp Immunol 101 1995 428 435
    • (1995) Clin Exp Immunol , vol.101 , pp. 428-435
    • Niessner, M1    Volk, BA.2
  • 13
    • 0030480323 scopus 로고    scopus 로고
    • Interleukin 10 suppresses experimental chronic, granulomatous inflammation induced by bacterial cell wall polymers
    • HH Herfarth SP Mohanty HC Rath S Tonkonogy RB. Sartor Interleukin 10 suppresses experimental chronic, granulomatous inflammation induced by bacterial cell wall polymers Gut 39 1996 836 845
    • (1996) Gut , vol.39 , pp. 836-845
    • Herfarth, HH1    Mohanty, SP2    Rath, HC3    Tonkonogy, S4    Sartor, RB.5
  • 14
    • 0030835754 scopus 로고    scopus 로고
    • Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease
    • SJH Van Deventer CO Elson RN. Fedorak Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease Gastroenterology 113 1997 383 389
    • (1997) Gastroenterology , vol.113 , pp. 383-389
    • Van Deventer, SJH1    Elson, CO2    Fedorak, RN.3
  • 15
    • 0344651503 scopus 로고    scopus 로고
    • Safety, tolerance and activity of multiple doses of subcutaneous recombinant human interleukin-10 (rHuIL-10) in patients with mild to moderate active Crohn's disease
    • RN Fedorak A Gangl CO Elson C Gasche P Rutgeerts GD Haens S Schreiber G Wild Safety, tolerance and activity of multiple doses of subcutaneous recombinant human interleukin-10 (rHuIL-10) in patients with mild to moderate active Crohn's disease Gut 41 suppl 3 1997 A16
    • (1997) Gut , vol.41 , Issue.suppl 3 , pp. A16
    • Fedorak, RN1    Gangl, A2    Elson, CO3    Gasche, C4    Rutgeerts, P5    Haens, GD6    Schreiber, S7    Wild, G8
  • 16
    • 0025847582 scopus 로고
    • Matrix metalloproteinases and their inhibitors in connective tissue remodelling
    • JF Woessner Jr. Matrix metalloproteinases and their inhibitors in connective tissue remodelling FASEB J 5 1991 2145 2154
    • (1991) FASEB J , vol.5 , pp. 2145-2154
    • Woessner, JF1
  • 17
    • 0026896029 scopus 로고
    • The matrix-degrading metalloproteinases
    • LM. Matrisian The matrix-degrading metalloproteinases Bioessays 14 1992 455 463
    • (1992) Bioessays , vol.14 , pp. 455-463
    • Matrisian, LM.1
  • 19
    • 0023925510 scopus 로고
    • Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine
    • TT MacDonald J. Spencer Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine J Exp Med 167 1988 1341 1349
    • (1988) J Exp Med , vol.167 , pp. 1341-1349
    • MacDonald, TT1    Spencer, J.2
  • 20
    • 0027292917 scopus 로고
    • T cell activation can induce either mucosal destruction or adaptation in cultured human fetal small intestine
    • P Lionetti E Breese CP Braegger SH Murch J Taylor TT. MacDonald T cell activation can induce either mucosal destruction or adaptation in cultured human fetal small intestine Gastroenterology 105 1993 373 381
    • (1993) Gastroenterology , vol.105 , pp. 373-381
    • Lionetti, P1    Breese, E2    Braegger, CP3    Murch, SH4    Taylor, J5    MacDonald, TT.6
  • 21
    • 0027403273 scopus 로고
    • Activation of mucosal Vβ3+ T cells and tissue damage in human small intestine by the bacterial superantigen, Staphylococcus aureus enterotoxin B
    • + T cells and tissue damage in human small intestine by the bacterial superantigen, Staphylococcus aureus enterotoxin B Eur J Immunol 23 1993 664 668
    • (1993) Eur J Immunol , vol.23 , pp. 664-668
    • Lionetti, P1    Spencer, J2    Breese, EJ3    Murch, SH4    Taylor, J5    MacDonald, TT.6
  • 22
    • 0029814859 scopus 로고    scopus 로고
    • Proteolytic degradation of intestinal mucosal extracellular matrix following lamina propria T cell activation
    • SLF Pender P Lionetti SH Murch N Wathen TT. MacDonald Proteolytic degradation of intestinal mucosal extracellular matrix following lamina propria T cell activation Gut 39 1996 284 290
    • (1996) Gut , vol.39 , pp. 284-290
    • Pender, SLF1    Lionetti, P2    Murch, SH3    Wathen, N4    MacDonald, TT.5
  • 24
    • 0027943188 scopus 로고
    • Interleukin-10 modulates type I collagen and matrix metalloproteinase gene expression in cultured human skin fibroblasts
    • S Reitamo A Remitz K Tamai J. Uitto Interleukin-10 modulates type I collagen and matrix metalloproteinase gene expression in cultured human skin fibroblasts J Clin Invest 94 1994 2489 2492
    • (1994) J Clin Invest , vol.94 , pp. 2489-2492
    • Reitamo, S1    Remitz, A2    Tamai, K3    Uitto, J.4
  • 25
    • 0004314201 scopus 로고
    • Immunocytochemistry of lymphoreticular tumours. Immunocytochemistry
    • PG Isaacson DH. Wright Immunocytochemistry of lymphoreticular tumours. Immunocytochemistry JM Polak S van Noorden Practical applications in pathology & biology. 1983 Wright Bristol, England 249 261
    • (1983) , pp. 249-261
    • Isaacson, PG1    Wright, DH.2
  • 26
    • 0027441514 scopus 로고
    • Interleukin-2– and interferon-gamma–secreting T cells in normal and diseased human intestinal mucosa
    • E Breese CP Braegger CP Corrigan JA Walker-Smith TT. MacDonald Interleukin-2– and interferon-gamma–secreting T cells in normal and diseased human intestinal mucosa Immunology 78 1993 127 131
    • (1993) Immunology , vol.78 , pp. 127-131
    • Breese, E1    Braegger, CP2    Corrigan, CP3    Walker-Smith, JA4    MacDonald, TT.5
  • 27
    • 0028864991 scopus 로고
    • A distinct array of pro-inflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
    • HC Jung L Eckmann SK Yang A Panja J Fierer E Morzycka-Wroblewska MF. Kagnoff A distinct array of pro-inflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion J Clin Invest 95 1995 55 65
    • (1995) J Clin Invest , vol.95 , pp. 55-65
    • Jung, HC1    Eckmann, L2    Yang, SK3    Panja, A4    Fierer, J5    Morzycka-Wroblewska, E6    Kagnoff, MF.7
  • 28
    • 0028519227 scopus 로고
    • Targeting the glycosaminoglycan-binding sites on proteins
    • AD. Lander Targeting the glycosaminoglycan-binding sites on proteins Chem Biol 1 1994 73 78
    • (1994) Chem Biol , vol.1 , pp. 73-78
    • Lander, AD.1
  • 29
    • 0027394381 scopus 로고
    • Detection of glycosaminoglycans on the surface of human umbilical vein endothelial cells using gold-conjugated poly-L-lysin with silver enhancement
    • NJ Klein GI Shennan RS Heyderman M. Levin Detection of glycosaminoglycans on the surface of human umbilical vein endothelial cells using gold-conjugated poly-L-lysin with silver enhancement Histochem J 25 1993 291 298
    • (1993) Histochem J , vol.25 , pp. 291-298
    • Klein, NJ1    Shennan, GI2    Heyderman, RS3    Levin, M.4
  • 30
    • 0022085068 scopus 로고
    • EGF and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts
    • LM Matrisian N Glaichenhaus MC Gesnel R. Breathnach EGF and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts EMBO J 4 1985 1435 1440
    • (1985) EMBO J , vol.4 , pp. 1435-1440
    • Matrisian, LM1    Glaichenhaus, N2    Gesnel, MC3    Breathnach, R.4
  • 32
    • 0025340063 scopus 로고
    • Cellular localization of procollagen type I, III and IV procollagen gene transcripts in normal and fibrotic human liver
    • S Milani H Herbst D Schuppan C Surrenti EO Riecken H. Stein Cellular localization of procollagen type I, III and IV procollagen gene transcripts in normal and fibrotic human liver Am J Pathol 137 1990 59 70
    • (1990) Am J Pathol , vol.137 , pp. 59-70
    • Milani, S1    Herbst, H2    Schuppan, D3    Surrenti, C4    Riecken, EO5    Stein, H.6
  • 33
    • 0024503250 scopus 로고
    • High-affinity binding of staphylococcal enterotoxin A and B to HLADR
    • JD. Fraser High-affinity binding of staphylococcal enterotoxin A and B to HLADR Nature 339 1989 221 223
    • (1989) Nature , vol.339 , pp. 221-223
    • Fraser, JD.1
  • 34
    • 0028149312 scopus 로고
    • Localization of binding sites of Staphylococcal enterotoxin B (SEB), a superantigen for HLA-DR by inhibition with synthetic peptides of SEB
    • JL Komisar S Small-Harris J. Tseng Localization of binding sites of Staphylococcal enterotoxin B (SEB), a superantigen for HLA-DR by inhibition with synthetic peptides of SEB Infection Immun 62 1994 4775 4780
    • (1994) Infection Immun , vol.62 , pp. 4775-4780
    • Komisar, JL1    Small-Harris, S2    Tseng, J.3
  • 35
    • 0023127196 scopus 로고
    • Heterogeneity of non-lymphoid cells expressing HLA-D region antigens in human fetal gut
    • J Spencer TT MacDonald PG. Isaacson Heterogeneity of non-lymphoid cells expressing HLA-D region antigens in human fetal gut Clin Exp Immunol 67 1987 415 424
    • (1987) Clin Exp Immunol , vol.67 , pp. 415-424
    • Spencer, J1    MacDonald, TT2    Isaacson, PG.3
  • 36
    • 0023698166 scopus 로고
    • Stimulation of mucosal T cells in situ with anti-CD3 antibody: location of the activated T cells and their distribution within the mucosal micro-environment
    • T Monk J Spencer N Cerf-Bensussan TT. MacDonald Stimulation of mucosal T cells in situ with anti-CD3 antibody: location of the activated T cells and their distribution within the mucosal micro-environment Clin Exp Immunol 74 1988 216 222
    • (1988) Clin Exp Immunol , vol.74 , pp. 216-222
    • Monk, T1    Spencer, J2    Cerf-Bensussan, N3    MacDonald, TT.4
  • 37
    • 0023715676 scopus 로고
    • HLA-DR expression in human fetal intestinal epithelium
    • TT MacDonald A Weinel J. Spencer HLA-DR expression in human fetal intestinal epithelium Gut 29 1988 1342 1348
    • (1988) Gut , vol.29 , pp. 1342-1348
    • MacDonald, TT1    Weinel, A2    Spencer, J.3
  • 38
    • 0026000892 scopus 로고
    • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
    • R de Waal Malfyt J Haanen H Spits MG Roncarolo A te Velde C Figdor K Johnson R Kastelein H Yssel JE. de Vries Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression J Exp Med 174 1991 915 924
    • (1991) J Exp Med , vol.174 , pp. 915-924
    • de Waal Malfyt, R1    Haanen, J2    Spits, H3    Roncarolo, MG4    te Velde, A5    Figdor, C6    Johnson, K7    Kastelein, R8    Yssel, H9    de Vries, JE.10
  • 40
    • 0029012683 scopus 로고
    • IL-10 augments CD23 expression on U937 cells and downregulates IL-4–driven CD23 expression on cultured human blood monocytes: effects of IL-10 and other cytokines on cell phenotype and phagocytosis
    • A Spittler C Schiller M Willheim C Tempfer S Winkler G. Boltz-Nitulescu IL-10 augments CD23 expression on U937 cells and downregulates IL-4–driven CD23 expression on cultured human blood monocytes: effects of IL-10 and other cytokines on cell phenotype and phagocytosis Immunology 85 1995 311 317
    • (1995) Immunology , vol.85 , pp. 311-317
    • Spittler, A1    Schiller, C2    Willheim, M3    Tempfer, C4    Winkler, S5    Boltz-Nitulescu, G.6
  • 41
    • 0030028043 scopus 로고    scopus 로고
    • Matrix metalloproteinases in immunity
    • EJ Goetzl MJ Banda D. Leppert Matrix metalloproteinases in immunity J Immunol 156 1996 1 4
    • (1996) J Immunol , vol.156 , pp. 1-4
    • Goetzl, EJ1    Banda, MJ2    Leppert, D.3
  • 42
    • 0029041446 scopus 로고
    • T cell gelatinases mediate basement membrane transmigation in vitro
    • D Leppert E Waubant R Galardy NW Bunnett SL. Hauser T cell gelatinases mediate basement membrane transmigation in vitro J Immunol 154 1995 4379 4389
    • (1995) J Immunol , vol.154 , pp. 4379-4389
    • Leppert, D1    Waubant, E2    Galardy, R3    Bunnett, NW4    Hauser, SL.5
  • 43
    • 0022362769 scopus 로고
    • Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor
    • HG Welgus EJ Campbell Z Bar-Shavit RM Senior SL. Teitelbaum Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor J Clin Invest 76 1985 219 224
    • (1985) J Clin Invest , vol.76 , pp. 219-224
    • Welgus, HG1    Campbell, EJ2    Bar-Shavit, Z3    Senior, RM4    Teitelbaum, SL.5
  • 45
    • 0024330327 scopus 로고
    • SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages
    • SM Wilhelm IE Collier BL Marmer AZ Eisen GA Grant GI. Goldberg SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages J Biol Chem 264 1989 17213 17221
    • (1989) J Biol Chem , vol.264 , pp. 17213-17221
    • Wilhelm, SM1    Collier, IE2    Marmer, BL3    Eisen, AZ4    Grant, GA5    Goldberg, GI.6
  • 46
    • 0028021464 scopus 로고
    • Direct contact between T lymphocytes and monocytes is a major pathway for induction of metalloproteinase expression
    • S Lacraz P Isler E Vey HG Welgus JM. Dayer Direct contact between T lymphocytes and monocytes is a major pathway for induction of metalloproteinase expression J Biol Chem 269 1994 22027 22033
    • (1994) J Biol Chem , vol.269 , pp. 22027-22033
    • Lacraz, S1    Isler, P2    Vey, E3    Welgus, HG4    Dayer, JM.5
  • 48
    • 0028262145 scopus 로고
    • Expression of matrix metalloproteinase-2 and -9 during early human wound healing
    • T Salo M Makela M Kylmaniemi H Autio-Harmainen H. Larjava Expression of matrix metalloproteinase-2 and -9 during early human wound healing Lab Invest 70 1994 176 182
    • (1994) Lab Invest , vol.70 , pp. 176-182
    • Salo, T1    Makela, M2    Kylmaniemi, M3    Autio-Harmainen, H4    Larjava, H.5
  • 49
    • 0028855894 scopus 로고
    • IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes
    • S Lacraz LP Nicod R Chicheportiche HG Welgus JM. Dayer IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes J Clin Invest 96 1995 2304 2310
    • (1995) J Clin Invest , vol.96 , pp. 2304-2310
    • Lacraz, S1    Nicod, LP2    Chicheportiche, R3    Welgus, HG4    Dayer, JM.5
  • 50
    • 0027133427 scopus 로고
    • Cell matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing
    • UK Saarialho-Kere SO Kovacs AP Pentland JE Olerud HG Welgus WC. Parks Cell matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing J Clin Invest 92 1993 2858 2866
    • (1993) J Clin Invest , vol.92 , pp. 2858-2866
    • Saarialho-Kere, UK1    Kovacs, SO2    Pentland, AP3    Olerud, JE4    Welgus, HG5    Parks, WC.6
  • 51
    • 0026515544 scopus 로고
    • Interleu-kin-4 inhibition of prostaglandin E2 synthesis blocks interstitial collagenase and 92 kDa type IV collagenase/gelatinase production by human monocytes
    • ML Corcoran WG Stetler-Stevenson PD Brown LM. Wahl Interleu-kin-4 inhibition of prostaglandin E2 synthesis blocks interstitial collagenase and 92 kDa type IV collagenase/gelatinase production by human monocytes J Biol Chem 267 1992 515 519
    • (1992) J Biol Chem , vol.267 , pp. 515-519
    • Corcoran, ML1    Stetler-Stevenson, WG2    Brown, PD3    Wahl, LM.4
  • 52
    • 0027990831 scopus 로고
    • Interleukin 10 suppression of monocyte prostaglandin H synthase-2. Mechanism of inhibition of prostaglandin-dependent matrix metalloproteinase production
    • PM Mertz DL DeWitt WG Stetler-Stevenson LM. Wahl Interleukin 10 suppression of monocyte prostaglandin H synthase-2. Mechanism of inhibition of prostaglandin-dependent matrix metalloproteinase production J Biol Chem 269 1994 21322 21329
    • (1994) J Biol Chem , vol.269 , pp. 21322-21329
    • Mertz, PM1    DeWitt, DL2    Stetler-Stevenson, WG3    Wahl, LM.4
  • 53
    • 0024553162 scopus 로고
    • Dendritic cells and scavenger macrophages in chronic inflammatoary bowel disease
    • CA Seldenrijk HA Drexhage SG Meuwissen ST Pals CJ. Meijer Dendritic cells and scavenger macrophages in chronic inflammatoary bowel disease Gut 30 1989 486 491
    • (1989) Gut , vol.30 , pp. 486-491
    • Seldenrijk, CA1    Drexhage, HA2    Meuwissen, SG3    Pals, ST4    Meijer, CJ.5
  • 54
    • 0027409322 scopus 로고
    • Localisation of intestinal interleukin-1 activity and protein and gene expression to lamina propria cells
    • KR Youngman PL Simon GA West F Cominelli D Rachmilewitz JS Klein C. Fiocchi Localisation of intestinal interleukin-1 activity and protein and gene expression to lamina propria cells Gastroenterology 104 1993 749 758
    • (1993) Gastroenterology , vol.104 , pp. 749-758
    • Youngman, KR1    Simon, PL2    West, GA3    Cominelli, F4    Rachmilewitz, D5    Klein, JS6    Fiocchi, C.7
  • 56
    • 0024553788 scopus 로고
    • Interferon-γ directly affects barrier function of cultured intestinal epithelial monolayers
    • JL Madara J. Stafford Interferon-γ directly affects barrier function of cultured intestinal epithelial monolayers J Clin Invest 83 1989 724 727
    • (1989) J Clin Invest , vol.83 , pp. 724-727
    • Madara, JL1    Stafford, J.2
  • 57
    • 0027245531 scopus 로고
    • Interferon-γ modulation of epithelial barrier function: time course, reversibility, and site of cytokine binding
    • RB Adams SM Planchon JK. Roche Interferon-γ modulation of epithelial barrier function: time course, reversibility, and site of cytokine binding J Immunol 150 1993 2356 2363
    • (1993) J Immunol , vol.150 , pp. 2356-2363
    • Adams, RB1    Planchon, SM2    Roche, JK.3
  • 58
    • 0031011849 scopus 로고    scopus 로고
    • Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion
    • KL Madsen SA Lewis MM Tavernini J Hibbard RN. Fedorak Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion Gastroenterology 113 1997 151 159
    • (1997) Gastroenterology , vol.113 , pp. 151-159
    • Madsen, KL1    Lewis, SA2    Tavernini, MM3    Hibbard, J4    Fedorak, RN.5
  • 59
    • 0026095235 scopus 로고
    • Increased activation of isolated intestinal lamina propria mononuclear cells in inflammatory bowel disease
    • S Schreiber RP MacDermott A Raedler R Pinnau MJ Bertovich GS. Nash Increased activation of isolated intestinal lamina propria mononuclear cells in inflammatory bowel disease Gastroenterology 101 1991 1020 1030
    • (1991) Gastroenterology , vol.101 , pp. 1020-1030
    • Schreiber, S1    MacDermott, RP2    Raedler, A3    Pinnau, R4    Bertovich, MJ5    Nash, GS.6
  • 61
    • 0027451455 scopus 로고
    • Enhanced secretion of tumor necrosis factor-alpha, IL-6 and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
    • HC Reinecker M Steffen T Witthoeft I Pflueger S Schreiber RP MacDermott A. Raedler Enhanced secretion of tumor necrosis factor-alpha, IL-6 and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease Clin Exp Immunol 94 1993 174 181
    • (1993) Clin Exp Immunol , vol.94 , pp. 174-181
    • Reinecker, HC1    Steffen, M2    Witthoeft, T3    Pflueger, I4    Schreiber, S5    MacDermott, RP6    Raedler, A.7
  • 62
    • 0021352632 scopus 로고
    • Enhanced synthesis of leukotriene B4 by colonic mucosa in inflammatory bowel disease
    • 4 by colonic mucosa in inflammatory bowel disease Gastroenterology 86 1984 453 460
    • (1984) Gastroenterology , vol.86 , pp. 453-460
    • Sharon, P1    Stenson, WF.2
  • 64
    • 0028347680 scopus 로고
    • Distribution of the matrix metalloproteinases stromelysin, gelatinase A and B, and collagenase in Crohn's disease and normal intestine
    • CJ Bailey RM Hembry A Alexander MH Ir ving ME Grant CA. Shuttleworth Distribution of the matrix metalloproteinases stromelysin, gelatinase A and B, and collagenase in Crohn's disease and normal intestine J Clin Pathol 47 1994 113 116
    • (1994) J Clin Pathol , vol.47 , pp. 113-116
    • Bailey, CJ1    Hembry, RM2    Alexander, A3    Ir ving, MH4    Grant, ME5    Shuttleworth, CA.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.