Microsporins A and B: new histone deacetylase inhibitors from the marine-derived fungus Microsporum cf. gypseum and the solid-phase synthesis of microsporin A

Tetrahedron

Volumn 63, Issue 28, 2007, Pages 6535-6541

  Gu, Wenxin ^a   Cueto, Mercedes ^b   Jensen, Paul R ^b   Fenical, William ^b   Silverman, Richard B ^a  

^a Center for Drug Discovery and Chemical Biology ^*  (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Aoda; Cyclic tetrapeptide; Cytotoxins; Histone deacetylase; Marine fungus; Microsporum gypseum; Solid phase synthesis

Indexed keywords

CYCLOPEPTIDE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; MICROSPORIN A; MICROSPORIN B; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN HCT116; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MICROSPORUM GYPSEUM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; SOLID PHASE SYNTHESIS; STRUCTURE ACTIVITY RELATION; UNITED STATES;

ARTHRODERMA GYPSEUM; BRYOZOA; BUGULA; FUNGI;

EID: 34249290099     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2007.04.025     Document Type: Article

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