Apicidins: Novel cyclic tetrapeptides as coccidiostats and antimalarial agents from Fusarium pallidoroseum

Tetrahedron Letters

Volumn 37, Issue 45, 1996, Pages 8077-8080

  Singh, Sheo B ^a   Zink, Deborah L ^a   Polishook, Jon D ^a   Dombrowski, Anne W ^a   Darkin Rattray, Sandra J ^a   Schmatz, Dennis M ^a   Goetz, Michael A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ANTIPARASITIC AGENT; CYCLOPEPTIDE; HISTONE DEACETYLASE;

ANIMAL MODEL; APICOMPLEXA; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; FUSARIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALARIA; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PLASMODIUM BERGHEI;

ANIMALIA; APICOMPLEXA; FUSARIUM; FUSARIUM PALLIDOROSEUM; PLASMODIUM BERGHEI;

EID: 0030569401     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01844-8     Document Type: Article

References (11)

1. 1. For detailed discussions of biological activities and the comparison of activities with other tetrapeptides, refer to: Darkin-Rattray, S. J.; Gurnett, A. M.; Myers, R. M.; Dulski, P. M.; Crumley, T. M.; Alloco, J.; Cannova, C.; Meinke, P. T.; Colletti, S. L.; Bednarek, M. A.; Singh, S.; B.; Goetz, M. A.; Dombrowski, A. W.; Polishook, J. D.; and Schmatz, D. M. Proc. Natl. Acad. Sci. (U. S. A.) 1996 (in press).
2. 2. Fusarium pallidoroseum (Ascomycotina, Hypocreales; ATCC 74289) was isolated from branches of Acacia sps.; Guanacaste Conservation area, Costa Rica.
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