Synthesis of cephalexin with immobilized penicillin acylase at very high substrate concentrations in fully aqueous medium

Journal of Molecular Catalysis B: Enzymatic

Volumn 47, Issue 1-2, 2007, Pages 72-78

  Illanes, Andrés ^a   Wilson, Lorena ^a   Corrotea, Octavio ^a   Tavernini, Luigi ^a   Zamorano, Francisca ^a   Aguirre, Carolina ^b  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO   (Chile)

^b UNIVERSIDAD CATÓLICA DE LA SANTÍSIMA CONCEPCIÓN   (Chile)

Author keywords

lactam antibiotics; Cephalexin; Immobilized enzymes; Kinetically controlled synthesis; Penicillin acylase

Indexed keywords

ENZYME IMMOBILIZATION; NUCLEOPHILES; ORGANIC SOLVENTS; PH EFFECTS; SUBSTRATES; VOLUMETRIC ANALYSIS;

CEPHALEXIN; COSOLVENT CONCENTRATION; PENICILLIN ACYLASE;

ANTIBIOTICS;

BETA LACTAM ANTIBIOTIC; CEFALEXIN; ETHYLENE GLYCOL; ORGANIC SOLVENT; PENICILLIN AMIDASE;

AQUEOUS SOLUTION; ARTICLE; DRUG SYNTHESIS; ENZYME KINETICS; ENZYME SUBSTRATE; NONHUMAN; PRODUCTIVITY; STOICHIOMETRY;

EID: 34249288648     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcatb.2007.04.003     Document Type: Article

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