Amidino benzimidazole inhibitors of bacterial two-component systems

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 12, 2001, Pages 1545-1548

  Weidner Wells, Michele A ^a   Ohemeng, Kwasi A ^a   Nguyen, Van N ^a   Fraga Spano, Stephanie ^a   Macielag, Mark J ^a   Werblood, Harvey M ^a   Foleno, Barbara D ^a   Webb, Glenda C ^a   Barrett, John F ^a   Hlasta, Dennis J ^a,b  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDINE; AMIDINOBENZIMIDAZOLE INHIBITOR; AMINO ACID DERIVATIVE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; BENZENE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; BENZOXAZOLE DERIVATIVE; BIPHENYL DERIVATIVE; DIAMIDINE DERIVATIVE; INDOLE DERIVATIVE; METHYL GROUP; NITRO DERIVATIVE; OXACILLIN; PROTEIN HISTIDINE KINASE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL INFECTION; COMPARTMENT MODEL; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG POTENCY; DRUG SENSITIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; IC 50; IN VITRO STUDY; MULTIDRUG RESISTANCE; NONHUMAN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMIDINES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BENZIMIDAZOLES; COMBINATORIAL CHEMISTRY TECHNIQUES; GRAM-POSITIVE BACTERIA; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 0035907479     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00024-5     Document Type: Article

References (11)