Antiviral and antiproliferative activity in vitro of some new benzimidazole derivatives

Pharmacology and Toxicology

Volumn 88, Issue 2, 2001, Pages 67-74

  Castelli, Mario ^a   Malagoli, Monica ^a   Lupo, Lucia ^a   Riccomi, Tiziana Rossi ^a   Casolari, Chiara ^a   Cermelli, Claudio ^a   Zanca, Andrea ^b   Baggio, Giosuè ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b CARLO POMA HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; DAUNORUBICIN;

ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS B; CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; VERO CELL;

COXSACKIEVIRUS; HUMAN ENTEROVIRUS B;

EID: 0035131060     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0773.2001.088002067.x     Document Type: Article

References (6)

1. Baltimore, D., H. J. Eggers, R. M. Franklin & I. Tamm: Poliovirus-induced RNA polymerase and the effects of virus-specific inhibitors on its production. Proc. Nat. Acad. Sci. USA 1963, 49, 843-849.
2. Dardiri, A. H., P. D. Delay & H. L. Bachrach: Effect of 2-(α-hydroxybenzyl)-benzimidazole on Teschen disease virus, pig enteric viruses and foot-and-mouth disease virus in kidney cell cultures. Can. J. Comp. Med 1964, 28, 161-168.
3. Denny, W. A., G. W. Rewcastle & B. C. Baguley: Potential antitumour agents. 59. Structure-activity relationship for 2-phenyl-benzimidazole-4-carboxamides, a new class of "minimal" DNA-intercalating agents which may not act via topoisomerase II. J. Med. Chem. 1990, 33, 814-819.
4. Dinter, Z.: Differenzierung einiger boviner Picorna-Viren mittels Guanidin und 2-(Alpha-Hydroxybenzyl)-Benzimidazol (HBB). Wien. Tierärtzl. Monatsschr. 1964, 51, 70-73.
5. Dulbecco, R.: La natura dei virus. In: R. Dulbecco and H. S. Ginsberg. (Eds.) Virologia. Zanichelli, Bologna, Italy, 1993, 813-814.
6. Edwards, D. J.: Nitroimidazole drugs, action and resistance mechanism. I. Mechanism of action. J. Antimicrob. Chemother. 1993, 31, 9-20.