Novel amidino-substituted benzimidazoles: Synthesis of compounds and inhibition of dipeptidyl peptidase III

Bioorganic Chemistry

Volumn 35, Issue 2, 2007, Pages 153-169

  Agić, Dejan ^a   Hranjec, Marijana ^b   Jajčanin, Nina ^c   Starčević, Kristina ^b   Karminski Zamola, Grace ^b   Abramić, Marija ^c  

^a JOSIP JURAJ STROSSMAYER UNIVERSITY OF OSIJEK   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

^c RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

Amidino substituted benzimidazoles; Dipeptidyl peptidase III inhibitors; Green chemistry

Indexed keywords

1,3 BIS[5 (2 IMIDAZOLINYL) 2 BENZIMIDAZOLYL] 2,4 DI O CHLOROPHENYLCYCLOBUTANE; 1,3 BIS[5 (2 IMIDAZOLINYL) 2 BENZIMIDAZOLYL] 2,4 DIPHENYLCYCLOBUTANE; 1,3 BIS[5 (2 IMIDAZOLINYL) 2 BENZOIMIDAZOLYL] 2,4 BIS(2 FURYL)CYCLOBUTANE; 1,3 BIS[5 (2 IMIDAZOLINYL) 2 BENZOIMIDAZOLYL] 2,4 BIS(2 THIENYL)CYCLOBUTANE; 1,3 BIS[5 (N AMIDINO) 2 BENZIMIDAZOLYL] 2,4 DI O CHLOROPHENYLCYCLOBUTANE; 1,3 BIS[5 (N AMIDINO) 2 BENZIMIDAZOLYL] 2,4 DIPHENYLCYCLOBUTANE; 1,3 BIS[5 (N ISOPROPYLAMIDINO) 2 BENZIMIDAZOLYL] 2,4 DI O CHLOROPHENYLCYCLOBUTANE; 1,3 BIS[5 (N ISOPROPYLAMIDINO) 2 BENZIMIDAZOLYL] 2,4 DIPHENYLCYCLOBUTANE; 2 (3H IMIDAZOL 4 YL) 1H BENZOIMIDAZOL 5 IMIDAZOLINYLAMIDINE; 2 (3H IMIDAZOL 4 YL) 1H BENZOIMIDAZOLE 5 CARBOXAMIDINE; BENZIMIDAZOLE DERIVATIVE; CYCLOBUTANE DERIVATIVE; DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE III; PEPTIDE; UNCLASSIFIED DRUG; VALORPHIN; WATER;

ARTICLE; CYCLIZATION; DRUG ACTIVITY; DRUG CONFORMATION; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INACTIVATION; ENZYME INHIBITION; IC 50; INHIBITION KINETICS; PHOTOCHEMISTRY; PRIORITY JOURNAL;

ADAMANTANE; ALGORITHMS; AMIDES; BENZIMIDAZOLES; CHEMISTRY, PHYSICAL; DIPEPTIDYL PEPTIDASES; ERYTHROCYTES; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA;

EID: 33847625986     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2006.11.002     Document Type: Article

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