Novel cyano- and N-isopropylamidino-substituted derivatives of benzo[b]thiophene-2-carboxanilides and benzo[b]thieno[2,3-c]quinolones: Synthesis, photochemical synthesis, crystal structure determination, and antitumor evaluation. 2

Journal of Medicinal Chemistry

Volumn 48, Issue 7, 2005, Pages 2346-2360

  Jarak, Ivana ^a   Kralj, Marijeta ^b   Šuman, Lidija ^b   Pavlović, Gordana ^c   Dogan, Jasna ^a,d   Piantanida, Ivo ^b   Žinić, Mladen ^b   Pavelić, Krešimir ^b   Karminski Zamola, Grace ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b RUDER BO KOVI INSTITUTE   (Croatia)

^c UNIVERSITY OF ZAGREB   (Croatia)

^d PLIVA CROATIA LTD   (Croatia)

Author keywords

[No Author keywords available]

Indexed keywords

2 (N' ISOPROPYLAMIDINO) 6 OXO 5,6 DIHYDRO[1]BENZOTHIENO[2,3 C]QUINOLINE; 2 (N' ISOPROPYLAMIDINO) 9 METHYL 6 OXO 5,6 DIHYDRO[1]BENZOTHIENO[2,3 C]QUINOLINE; 2 BROMO 9 (N' ISOPROPYLAMIDINO) 6 OXO 5,6 DIHYDRO[1]BENZOTHIENO[2,3 C]QUINOLINE; 2 CARBMETHOXY 9 (N' ISOPROPYLAMIDINO) 6 OXO 5,6 DIHYDRO[1]BENZOTHIENO[2,3 C]QUINOLINE; 3 CHLOROBENZO[B]THIOPHENE 2 CARBOXANILIDE DERIVATIVE; 6 CYANO N (4' CARBMETHOXYPHENYL) 3 CHLOROBENZO[B]THIOPHENE 2 CARBOXAMIDE; ANTINEOPLASTIC AGENT; BENZO[B]THIENO[2,3 C]QUINOLONE DERIVATIVE; BENZO[B]THIOPHENE 2 CARBOXANILIDE DERIVATIVE; DNA; DNA TOPOISOMERASE; METHYL 2 (N' ISOPROPYLAMIDINO) 6 OXO 5,6 DIHYDRO[1]BENZOTHIENO[2,3 C]QUINOLIN 9 CARBOXYLATE; RNA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DRUG DNA BINDING; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FIBROBLAST; HUMAN; HUMAN CELL; SPECTROSCOPY; STRUCTURE ANALYSIS;

AMIDINES; ANILIDES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; FIBROBLASTS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NITRILES; QUINOLONES; RNA; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 17144418456     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049541f     Document Type: Article

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