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Volumn 151, Issue 2, 2007, Pages 292-302

Continuous infusion of the cannabinoid WIN 55,212-2 to the site of a peripheral nerve injury reduces mechanical and cold hypersensitivity

Author keywords

Cannabinoid receptor; Nerve injury; Neuropathic pain; WIN 55,212 2

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; CANNABINOID; RIMONABANT;

EID: 34248590393     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707210     Document Type: Article
Times cited : (13)

References (63)
  • 1
    • 0038007619 scopus 로고    scopus 로고
    • Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurones by activating both the cannabinoid 1 receptor and the vannilloid receptor 1 in vitro
    • Ahluwalia J, Urban L, Bevan S, Nagy I (2003). Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurones by activating both the cannabinoid 1 receptor and the vannilloid receptor 1 in vitro. Eur J Neurosci 17: 2611-2618.
    • (2003) Eur J Neurosci , vol.17 , pp. 2611-2618
    • Ahluwalia, J.1    Urban, L.2    Bevan, S.3    Nagy, I.4
  • 6
    • 0036805146 scopus 로고    scopus 로고
    • Topical cannabinoid agonist, WIN55,212-2, reduces cornea-evoked trigeminal brain-stem activity in the rat
    • Bereiter DA, Bereiter DF, Hirata H (2002). Topical cannabinoid agonist, WIN55,212-2, reduces cornea-evoked trigeminal brain-stem activity in the rat. Pain 99: 547-556.
    • (2002) Pain , vol.99 , pp. 547-556
    • Bereiter, D.A.1    Bereiter, D.F.2    Hirata, H.3
  • 7
    • 0036460111 scopus 로고    scopus 로고
    • A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor
    • Boyd JG, Gordon T (2002). A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor. Eur J Neurosci 15: 613-626.
    • (2002) Eur J Neurosci , vol.15 , pp. 613-626
    • Boyd, J.G.1    Gordon, T.2
  • 8
    • 0034951162 scopus 로고    scopus 로고
    • The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a ratmodel of neuropathic pain
    • Bridges D, Ahmad KS, Rice ASC (2001). The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a ratmodel of neuropathic pain. Br J Pharmacol 133: 586-594.
    • (2001) Br J Pharmacol , vol.133 , pp. 586-594
    • Bridges, D.1    Ahmad, K.S.2    Rice, A.S.C.3
  • 9
    • 0038182182 scopus 로고    scopus 로고
    • Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridisation and immunohistochemistry
    • Bridges D, Rice ASC, Egertova M, Elphick MR, Winter J, Michael GJ (2003). Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridisation and immunohistochemistry. Neuroscience 119: 803-812.
    • (2003) Neuroscience , vol.119 , pp. 803-812
    • Bridges, D.1    Rice, A.S.C.2    Egertova, M.3    Elphick, M.R.4    Winter, J.5    Michael, G.J.6
  • 10
    • 0032537734 scopus 로고    scopus 로고
    • Control of pain initiation by endogenous cannabinoids
    • Calignano A, La Rana G, Giuffrida A, Piomelli D (1998). Control of pain initiation by endogenous cannabinoids. Nature 394: 277-281.
    • (1998) Nature , vol.394 , pp. 277-281
    • Calignano, A.1    La Rana, G.2    Giuffrida, A.3    Piomelli, D.4
  • 11
    • 0028058081 scopus 로고
    • Behavioral manifestations of an experimental model for peripheral neuropathy produced by spinal nerve ligation in the primate
    • Carlton SM, Lekan HA, Kim SH, Chung JM (1994). Behavioral manifestations of an experimental model for peripheral neuropathy produced by spinal nerve ligation in the primate. Pain 56: 155-166.
    • (1994) Pain , vol.56 , pp. 155-166
    • Carlton, S.M.1    Lekan, H.A.2    Kim, S.H.3    Chung, J.M.4
  • 12
    • 1242296234 scopus 로고    scopus 로고
    • Repeated treatment with the synthetic cannabinoid WIN 55,212-2 reduces both hyperalgesia and production of pronociceptive mediators in a rat model of neuropathic pain
    • Costa B, Colleoni M, Conti S, Trovato AE, Bianchi M, Sotgiu ML et al. (2004). Repeated treatment with the synthetic cannabinoid WIN 55,212-2 reduces both hyperalgesia and production of pronociceptive mediators in a rat model of neuropathic pain. Br J Pharmacol 141: 4-8.
    • (2004) Br J Pharmacol , vol.141 , pp. 4-8
    • Costa, B.1    Colleoni, M.2    Conti, S.3    Trovato, A.E.4    Bianchi, M.5    Sotgiu, M.L.6
  • 13
    • 0037709373 scopus 로고    scopus 로고
    • Histamine induced responses are attenuated by a cannabinoid receptor in human skin
    • Dovrak M, Watkinson A, McGlone F, Rukwied R (2003). Histamine induced responses are attenuated by a cannabinoid receptor in human skin. Inflamm Res 52: 238-245.
    • (2003) Inflamm Res , vol.52 , pp. 238-245
    • Dovrak, M.1    Watkinson, A.2    McGlone, F.3    Rukwied, R.4
  • 14
    • 30844469806 scopus 로고    scopus 로고
    • Sodium Channels and mechanisms of neuropathic pain
    • Devor M (2006). Sodium Channels and mechanisms of neuropathic pain. J Pain 7: S3-S12.
    • (2006) J Pain , vol.7
    • Devor, M.1
  • 15
    • 8144229133 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naive rats and in rat models of inflammatory and neuropathic pain
    • Elmes SJR, Jhaveri MD, Smart D, Kendall DA, Chapman V (2004). Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naive rats and in rat models of inflammatory and neuropathic pain. Eur J Pharmacol 20: 2311-2320.
    • (2004) Eur J Pharmacol , vol.20 , pp. 2311-2320
    • Elmes, S.J.R.1    Jhaveri, M.D.2    Smart, D.3    Kendall, D.A.4    Chapman, V.5
  • 16
    • 0036281114 scopus 로고    scopus 로고
    • The effect of cannabinoids on capsaicin-evoked calcitonin gene-related peptide (CGRP) release from the isolated paw skin of diabetic and nondiabetic rats
    • Ellington HC, Cotter MA, Cameron NE, Ross RA (2002). The effect of cannabinoids on capsaicin-evoked calcitonin gene-related peptide (CGRP) release from the isolated paw skin of diabetic and nondiabetic rats. Neuropharmacology 42: 966-975.
    • (2002) Neuropharmacology , vol.42 , pp. 966-975
    • Ellington, H.C.1    Cotter, M.A.2    Cameron, N.E.3    Ross, R.A.4
  • 17
    • 0035059241 scopus 로고    scopus 로고
    • The role of central and peripheral cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain
    • Fox A, Kesingland A, Gentry C, McNair K, Patel S, Urban L et al. (2001). The role of central and peripheral cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain. Pain 92: 91-100.
    • (2001) Pain , vol.92 , pp. 91-100
    • Fox, A.1    Kesingland, A.2    Gentry, C.3    McNair, K.4    Patel, S.5    Urban, L.6
  • 18
    • 17344380844 scopus 로고    scopus 로고
    • Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
    • Galve-Roperh I, Sanchez C, Cortes LM, Del Pulgar TG, Izquierdo M, Guzman M (2000). Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat Med 6: 31-39.
    • (2000) Nat Med , vol.6 , pp. 31-39
    • Galve-Roperh, I.1    Sanchez, C.2    Cortes, L.M.3    Del Pulgar, T.G.4    Izquierdo, M.5    Guzman, M.6
  • 19
    • 33646748276 scopus 로고    scopus 로고
    • Antihyperalgesic effects of local injections of anandamide, ibuprofen, rofecoxiib and their combinations in a model of neuropathic pain
    • Guindon J, Beaulieu P (2006). Antihyperalgesic effects of local injections of anandamide, ibuprofen, rofecoxiib and their combinations in a model of neuropathic pain. Neuropharmacology 50: 814-823.
    • (2006) Neuropharmacology , vol.50 , pp. 814-823
    • Guindon, J.1    Beaulieu, P.2
  • 20
    • 33846369794 scopus 로고    scopus 로고
    • Further characterisation of a rat model of varicella zoster virus (VZV)-associated pain: Relationship between mechanical hypersensitivity and anxiety-related behaviour; and the influence of analgesic drugs
    • Hasnie FS, Breuer J, Parker S, Wallace VCJ, Blackbeard J, Lever I et al. (2006). Further characterisation of a rat model of varicella zoster virus (VZV)-associated pain: relationship between mechanical hypersensitivity and anxiety-related behaviour; and the influence of analgesic drugs. Neuroscience 144: 1495-1508.
    • (2006) Neuroscience , vol.144 , pp. 1495-1508
    • Hasnie, F.S.1    Breuer, J.2    Parker, S.3    Wallace, V.C.J.4    Blackbeard, J.5    Lever, I.6
  • 21
    • 33846583290 scopus 로고    scopus 로고
    • Analgesic therapy in postherpetic neuralgia: A quantitative systematic review
    • Hempenstall K, Nurmikko TJ, Johnson RW, A'Hern R, Rice ASC (2005). Analgesic therapy in postherpetic neuralgia: a quantitative systematic review. PLoS Med 2: 628-644.
    • (2005) PLoS Med , vol.2 , pp. 628-644
    • Hempenstall, K.1    Nurmikko, T.J.2    Johnson, R.W.3    A'Hern, R.4    Rice, A.S.C.5
  • 22
    • 11244260452 scopus 로고    scopus 로고
    • Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people
    • Henquet C, Krabbendam L, Spauwen J, Kaplan C, Lieb R, Wittchen HU et al. (2005). Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people. Br Med J 330: 11.
    • (2005) Br Med J , vol.330 , pp. 11
    • Henquet, C.1    Krabbendam, L.2    Spauwen, J.3    Kaplan, C.4    Lieb, R.5    Wittchen, H.U.6
  • 23
    • 0342762087 scopus 로고    scopus 로고
    • The analgesic effects of R(+)-WIN55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain
    • Herzberg U, Eliav E, Bennett GJ, Kopin IJ (1997). The analgesic effects of R(+)-WIN55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain. Neurosci Lett 221: 157-160.
    • (1997) Neurosci Lett , vol.221 , pp. 157-160
    • Herzberg, U.1    Eliav, E.2    Bennett, G.J.3    Kopin, I.J.4
  • 24
    • 0041836218 scopus 로고    scopus 로고
    • Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS
    • Ibrahim MM, Deng H, Zvonok A, Cockayne DA, Kwan J, Mata HP et al. (2003). Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS. Proc Natl Acad Sci USA 100: 10529-10533.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10529-10533
    • Ibrahim, M.M.1    Deng, H.2    Zvonok, A.3    Cockayne, D.A.4    Kwan, J.5    Mata, H.P.6
  • 25
    • 20044368975 scopus 로고    scopus 로고
    • CB-2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids
    • Ibrahim MM, Porreca F, Lai J, Albrecht PJ, Rice FL, Khodortova A et al. (2005). CB-2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids. Proc Natl Acad Sci USA 102: 3039-3098.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3039-3098
    • Ibrahim, M.M.1    Porreca, F.2    Lai, J.3    Albrecht, P.J.4    Rice, F.L.5    Khodortova, A.6
  • 26
    • 0031776783 scopus 로고    scopus 로고
    • The antihyperalgesic actions of the cannabinoid anandamide and the putative CB2 agonist palmitoylethanolamide investigated in models of visceral and somatic inflammatory pain
    • Jaggar SI, Hasnie FS, Sellaturay S, Rice ASC (1998). The antihyperalgesic actions of the cannabinoid anandamide and the putative CB2 agonist palmitoylethanolamide investigated in models of visceral and somatic inflammatory pain. Pain 76: 189-199.
    • (1998) Pain , vol.76 , pp. 189-199
    • Jaggar, S.I.1    Hasnie, F.S.2    Sellaturay, S.3    Rice, A.S.C.4
  • 27
    • 2442480915 scopus 로고    scopus 로고
    • Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury
    • Johanek LM, Simone DA (2004). Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury. Pain 109: 432-442.
    • (2004) Pain , vol.109 , pp. 432-442
    • Johanek, L.M.1    Simone, D.A.2
  • 28
    • 0037146652 scopus 로고    scopus 로고
    • 2+ influx in intermediate-size primary afferent neurones of adult rats
    • 2+ influx in intermediate-size primary afferent neurones of adult rats. Neuroscience 115: 613-625.
    • (2002) Neuroscience , vol.115 , pp. 613-625
    • Khasabova, I.A.1    Simone, D.A.2    Seybold, V.S.3
  • 29
    • 0026727999 scopus 로고
    • An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat
    • Kim SH, Chung JM (1992). An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50: 355-363.
    • (1992) Pain , vol.50 , pp. 355-363
    • Kim, S.H.1    Chung, J.M.2
  • 31
    • 0141738711 scopus 로고    scopus 로고
    • Upregulation of spinal cannabinoid-1-receptors following nerve injury, enhances the effects of Win 55,212-2 on neuropathic pain behaviours in rats
    • Lim G, Sung B, Ji R-R, Mao J (2003). Upregulation of spinal cannabinoid-1-receptors following nerve injury, enhances the effects of Win 55,212-2 on neuropathic pain behaviours in rats. Pain 105: 275-283.
    • (2003) Pain , vol.105 , pp. 275-283
    • Lim, G.1    Sung, B.2    Ji, R.-R.3    Mao, J.4
  • 32
    • 0034672688 scopus 로고    scopus 로고
    • Partial sciatic nerve transection as a model of neuropathic pain: A qualitative neuropathological study
    • Lindenlaub T, Sommer C (2000). Partial sciatic nerve transection as a model of neuropathic pain: a qualitative neuropathological study. Pain 98: 97-106.
    • (2000) Pain , vol.98 , pp. 97-106
    • Lindenlaub, T.1    Sommer, C.2
  • 33
    • 0033956629 scopus 로고    scopus 로고
    • Two distinctive anti-nociceptive systems in rats with pathological pain
    • Mao J, Price DD, Lu J, Keniston L, Mayer DJ (2000). Two distinctive anti-nociceptive systems in rats with pathological pain. Neurosci Lett 280: 13-16.
    • (2000) Neurosci Lett , vol.280 , pp. 13-16
    • Mao, J.1    Price, D.D.2    Lu, J.3    Keniston, L.4    Mayer, D.J.5
  • 34
    • 0041842648 scopus 로고    scopus 로고
    • Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia
    • Molina-Holgado F, Pinteaux E, Moore JD, Molina-Holgado E, Guaza C, Gibson RM et al. (2003). Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia. J Neurosci 23: 6470-6474.
    • (2003) J Neurosci , vol.23 , pp. 6470-6474
    • Molina-Holgado, F.1    Pinteaux, E.2    Moore, J.D.3    Molina-Holgado, E.4    Guaza, C.5    Gibson, R.M.6
  • 35
    • 0037475146 scopus 로고    scopus 로고
    • Aperipheral cannabinoid mechanism suppresses spinal fos protein expression and pain behaviour in a rat model of inflammation
    • Nackley AG, Suplita II, Hohmann AG (2003). Aperipheral cannabinoid mechanism suppresses spinal fos protein expression and pain behaviour in a rat model of inflammation. Neuroscience 117: 650-670.
    • (2003) Neuroscience , vol.117 , pp. 650-670
    • Nackley, A.G.1
  • 36
    • 8644274638 scopus 로고    scopus 로고
    • Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation
    • Nackley AG, Zvonok AM, Makriyannis A, Hohmann AG (2004). Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation. J Neurophysiol 92: 3562-3574.
    • (2004) J Neurophysiol , vol.92 , pp. 3562-3574
    • Nackley, A.G.1    Zvonok, A.M.2    Makriyannis, A.3    Hohmann, A.G.4
  • 37
    • 33646508077 scopus 로고    scopus 로고
    • Suppression by WIN55212-2, a cannabinoid receptor agonist, of inflammatory reactions in mouse ear: Interference with the actions of an endogenous ligand, 2- arachidonoylglycerol
    • Oka S,Wakui J, GokohM, Kishimoto S, Sugiura T (2006). Suppression by WIN55212-2, a cannabinoid receptor agonist, of inflammatory reactions in mouse ear: Interference with the actions of an endogenous ligand, 2- arachidonoylglycerol. Eur J Pharmacol 538: 154-162.
    • (2006) Eur J Pharmacol , vol.538 , pp. 154-162
    • Oka, S.1    Wakui, J.2    Gokoh, M.3    Kishimoto, S.4    Sugiura, T.5
  • 38
    • 27644549880 scopus 로고    scopus 로고
    • A cannabinoid agonist WIN55,212-2 reduces neuropathic nociception induced by paclitaxel in rats
    • Pascual D, Goicoechea C, Suardiaz M, Martin MI (2005). A cannabinoid agonist WIN55,212-2 reduces neuropathic nociception induced by paclitaxel in rats. Pain 118: 23-34.
    • (2005) Pain , vol.118 , pp. 23-34
    • Pascual, D.1    Goicoechea, C.2    Suardiaz, M.3    Martin, M.I.4
  • 39
    • 0035150352 scopus 로고    scopus 로고
    • Cannabinoids and pain
    • Pertwee RG (2001). Cannabinoids and pain. Prog Neurobiol 63: 569-611.
    • (2001) Prog Neurobiol , vol.63 , pp. 569-611
    • Pertwee, R.G.1
  • 40
    • 0141538206 scopus 로고    scopus 로고
    • Antagonism between the anti-inflammatory activity of the cannabinoid WIN 55212-2 and SR 141716A
    • Pozzi O, Misiano P, Clark GD, Visentin L (2003). Antagonism between the anti-inflammatory activity of the cannabinoid WIN 55212-2 and SR 141716A. Pharmacology 69: 158-163.
    • (2003) Pharmacology , vol.69 , pp. 158-163
    • Pozzi, O.1    Misiano, P.2    Clark, G.D.3    Visentin, L.4
  • 42
    • 0033986604 scopus 로고    scopus 로고
    • Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells
    • Puffenbarger R, Boothe AC, Cabral GA (2000). Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells. Glia 29: 58-69.
    • (2000) Glia , vol.29 , pp. 58-69
    • Puffenbarger, R.1    Boothe, A.C.2    Cabral, G.A.3
  • 43
    • 32944479103 scopus 로고    scopus 로고
    • Cannabinoids
    • Koltzenburg M, McMahon SB eds, Elsevier: London
    • Rice ASC (2005). Cannabinoids. In: Koltzenburg M, McMahon SB (eds). Melzack and Wall: Textbook of Pain. Elsevier: London.
    • (2005) Melzack and Wall: Textbook of Pain
    • Rice, A.S.C.1
  • 44
    • 32944466713 scopus 로고    scopus 로고
    • New treatments for neuropathic pain
    • Rice ASC, Hill RG (2006). New treatments for neuropathic pain. Ann Rev Med 57: 535-551.
    • (2006) Ann Rev Med , vol.57 , pp. 535-551
    • Rice, A.S.C.1    Hill, R.G.2
  • 46
    • 0031779305 scopus 로고    scopus 로고
    • Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors
    • Richardson JD, Kilo S, Hargreaves KM (1998b). Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. Pain 75: 111-119.
    • (1998) Pain , vol.75 , pp. 111-119
    • Richardson, J.D.1    Kilo, S.2    Hargreaves, K.M.3
  • 47
  • 48
    • 0344405669 scopus 로고    scopus 로고
    • Cannabinoid agonists attenuate capsaicin-induced responses in human skin
    • Rukwied R,Watkinson A, McGlone F, Dvorak M (2003). Cannabinoid agonists attenuate capsaicin-induced responses in human skin. Pain 102: 283-288.
    • (2003) Pain , vol.102 , pp. 283-288
    • Rukwied, R.1    Watkinson, A.2    McGlone, F.3    Dvorak, M.4
  • 49
    • 23244444097 scopus 로고    scopus 로고
    • Inhibitory effects on CB1 and CB2 receptor agonists on responses of DRG neurones and dorsal horn neurones in neuropathic rats
    • Sagar DR, Kelly S, Millns PJ, O'Shaughnessey CT, Kendall D, Chapman V (2005). Inhibitory effects on CB1 and CB2 receptor agonists on responses of DRG neurones and dorsal horn neurones in neuropathic rats. Eur J Neurosci 22: 371-379.
    • (2005) Eur J Neurosci , vol.22 , pp. 371-379
    • Sagar, D.R.1    Kelly, S.2    Millns, P.J.3    O'Shaughnessey, C.T.4    Kendall, D.5    Chapman, V.6
  • 50
    • 22744435568 scopus 로고    scopus 로고
    • Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor
    • Savinaninen JR, Kokkola T, Salo OMH, Poso A, Jarvinen T, Laitinen JT (2005). Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor. Br J Pharmacol 145: 636-645.
    • (2005) Br J Pharmacol , vol.145 , pp. 636-645
    • Savinaninen, J.R.1    Kokkola, T.2    Salo, O.M.H.3    Poso, A.4    Jarvinen, T.5    Laitinen, J.T.6
  • 51
    • 1842685334 scopus 로고    scopus 로고
    • Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat
    • Scott DA, Wright CE, Angus JA (2004). Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat. Pain 109: 124-131.
    • (2004) Pain , vol.109 , pp. 124-131
    • Scott, D.A.1    Wright, C.E.2    Angus, J.A.3
  • 52
    • 0025167399 scopus 로고
    • A novel behavioural model of neuropathic pain disorders produced in rats by partial sciatic nerve injury
    • Seltzer Z, Dubner R, Yoram S (1990). A novel behavioural model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 43: 205-218.
    • (1990) Pain , vol.43 , pp. 205-218
    • Seltzer, Z.1    Dubner, R.2    Yoram, S.3
  • 53
    • 0037966402 scopus 로고    scopus 로고
    • Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats
    • Sokal DM, Elmes SJR, Kendall DA, Chapman V (2003). Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats. Neuropharmacology 45: 404-411.
    • (2003) Neuropharmacology , vol.45 , pp. 404-411
    • Sokal, D.M.1    Elmes, S.J.R.2    Kendall, D.A.3    Chapman, V.4
  • 54
    • 0032080243 scopus 로고    scopus 로고
    • Hyperalgesia in experimental neuropathy is dependent on the TNF receptor 1
    • Sommer C, Schmidt C, George A (1998). Hyperalgesia in experimental neuropathy is dependent on the TNF receptor 1. Exp Neurol 151: 138-142.
    • (1998) Exp Neurol , vol.151 , pp. 138-142
    • Sommer, C.1    Schmidt, C.2    George, A.3
  • 55
    • 0141955927 scopus 로고    scopus 로고
    • Somata of nerve-injured sensory neurones exhibit enhances responses to inflammtory mediators
    • Song X-J, Zhang J-M, Hu S-J, LaMotte RH (2003). Somata of nerve-injured sensory neurones exhibit enhances responses to inflammtory mediators. Pain 104: 701-709.
    • (2003) Pain , vol.104 , pp. 701-709
    • Song, X.-J.1    Zhang, J.-M.2    Hu, S.-J.3    LaMotte, R.H.4
  • 56
    • 20044386244 scopus 로고    scopus 로고
    • Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibres and adnexal structures in human skin
    • Ständer S, Schmelz M, Metze D, Luger TM, Rukweid R (2005). Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibres and adnexal structures in human skin. J Dermatol Sci 38: 177-188.
    • (2005) J Dermatol Sci , vol.38 , pp. 177-188
    • Ständer, S.1    Schmelz, M.2    Metze, D.3    Luger, T.M.4    Rukweid, R.5
  • 57
    • 1642513434 scopus 로고    scopus 로고
    • Peri-sciatic administration of indomethacin early after nerve injury can attenuate the development of tactile allodynia in a rat model of L5 single spinal nerve injury
    • Takahashi M, Kawaguchi M, Shimada K, Konishi N, Furuya H, Nakashima T (2004). Peri-sciatic administration of indomethacin early after nerve injury can attenuate the development of tactile allodynia in a rat model of L5 single spinal nerve injury. Neurosci Lett 356: 37-40.
    • (2004) Neurosci Lett , vol.356 , pp. 37-40
    • Takahashi, M.1    Kawaguchi, M.2    Shimada, K.3    Konishi, N.4    Furuya, H.5    Nakashima, T.6
  • 58
    • 0035866048 scopus 로고    scopus 로고
    • Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation
    • Tognetto M, Amadesi S, Harrison S, Creminon C, Trevisani M, Carreras M et al. (2001). Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation. J Neurosci 21: 1104-1109.
    • (2001) J Neurosci , vol.21 , pp. 1104-1109
    • Tognetto, M.1    Amadesi, S.2    Harrison, S.3    Creminon, C.4    Trevisani, M.5    Carreras, M.6
  • 59
    • 7444268551 scopus 로고    scopus 로고
    • The effect of WIN 55,212-2, a cannabinoid agonist, on tactile allodynia in diabetic rats
    • Ulugol A, Karadag HC, Ipci Y, Tarner M, Dokmeci I (2004). The effect of WIN 55,212-2, a cannabinoid agonist, on tactile allodynia in diabetic rats. Neurosci Lett 371: 167-170.
    • (2004) Neurosci Lett , vol.371 , pp. 167-170
    • Ulugol, A.1    Karadag, H.C.2    Ipci, Y.3    Tarner, M.4    Dokmeci, I.5
  • 60
    • 34248560620 scopus 로고    scopus 로고
    • The Characterisation of Rodent Models of HIV - gp120 and Antiretroviral - Associated Painful Peripheral Neuropathy
    • IASP Press: USA. 67-P44
    • Wallace VCJ, McMahon SB, Rice ASC (2005). The Characterisation of Rodent Models of HIV - gp120 and Antiretroviral - Associated Painful Peripheral Neuropathy. 11th World Congress on Pain Abstracts 2005. IASP Press: USA. 67-P44.
    • (2005) 11th World Congress on Pain Abstracts 2005
    • Wallace, V.C.J.1    McMahon, S.B.2    Rice, A.S.C.3
  • 61
    • 1842611884 scopus 로고    scopus 로고
    • Cannabinoids and neuroinflammation
    • Walter L, Stella N (2004). Cannabinoids and neuroinflammation. Br J Pharmacol 141: 775-785.
    • (2004) Br J Pharmacol , vol.141 , pp. 775-785
    • Walter, L.1    Stella, N.2
  • 62
    • 24044458606 scopus 로고    scopus 로고
    • Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons
    • Wotherspoon G, Fox A, McIntyre P, Colley S, Bevan S, Winter J (2005). Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons. Neuroscience 135: 235-245.
    • (2005) Neuroscience , vol.135 , pp. 235-245
    • Wotherspoon, G.1    Fox, A.2    McIntyre, P.3    Colley, S.4    Bevan, S.5    Winter, J.6
  • 63
    • 19444373244 scopus 로고    scopus 로고
    • Cannabinoids produce neuroprotection by reducing intracellular calcium release from ryanodine-sensitive stores
    • Zhuang S-Y, Bridges D, Grigorenko E, McCloud S, Boon A, Hampson RE et al. (2005). Cannabinoids produce neuroprotection by reducing intracellular calcium release from ryanodine-sensitive stores. Neuropharmacology 48: 1086-1096.
    • (2005) Neuropharmacology , vol.48 , pp. 1086-1096
    • Zhuang, S.-Y.1    Bridges, D.2    Grigorenko, E.3    McCloud, S.4    Boon, A.5    Hampson, R.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.