The effect of WIN 55,212-2, a cannabinoid agonist, on tactile allodynia in diabetic rats

Neuroscience Letters

Volumn 371, Issue 2-3, 2004, Pages 167-170

  Ulugol, Ahmet ^a   Karadag, Hakan C ^a   Ipci, Yesim ^a   Tamer, Melek ^a   Dokmeci, Ismet ^a  

^a TRAKYA UNIVERSITY   (Turkey)

Author keywords

Allodynia; Cannabinoids; Diabetes; Neuropathy; Pain; WIN 55,212 2

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID RECEPTOR AGONIST;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DIABETIC NEUROPATHY; DRUG EFFECT; FOOT; HINDLIMB; HYPERALGESIA; MECHANICAL STIMULATION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; THERMAL STIMULATION; TOUCH;

ANIMALS; CANNABINOIDS; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MORPHOLINES; NAPHTHALENES; PAIN MEASUREMENT; RATS; RATS, WISTAR; TOUCH;

EID: 7444268551     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.08.061     Document Type: Article

References (27)

1. F. Benedetti, S. Vighetti, M. Amanzio, C. Casadio, A. Oliaro, B. Bergamasco, and G. Maggi Dose-response relationship of opioids in nociceptive and neuropathic postoperative pain Pain 74 1998 205 211
2. D. Bridges, K. Ahmad, and A.S.C. Rice The synthetic cannabinoid WIN 55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain Br. J. Pharmacol. 133 2001 586 594
3. N.A. Calcutt, M.C. Jorge, T.L. Yaksh, and S.R. Chaplan Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine Pain 68 1996 293 299
4. S.R. Chaplan, F.W. Bach, J.W. Pogrel, J.M. Chung, and T.L. Yaksh Quantitative assessment of tactile allodynia in the rat paw J. Neurosci. Methods 53 1994 55 63
5. C. Courteix, A. Eschalier, and J. Lavarenne Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic pain Pain 53 1993 81 88
6. W.J. Dixon Efficiency analysis of experimental observations Ann. Rev. Pharmacol. Toxicol. 20 1980 441 462
7. A. Dogrul, H. Gul, A. Akar, O. Yildiz, F. Bilgin, and E. Guzeldemir Topical cannabinoid antinociception: synergy with spinal sites Pain 105 2003 11 16
8. A. Dogrul, H. Gul, O. Yildiz, F. Bilgin, and M.E. Guzeldemir Cannabinoids block tactile allodynia in diabetic mice without attenuation of its antinociceptive effect Neurosci. Lett. 368 2004 82 86
9. M.J. Field, S. McCleary, J. Hughes, and L. Singh Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat Pain 80 1999 391 398
10. A. Fox, C. Eastwood, C. Gentry, D. Manning, and L. Urban Critical evaluation of the streptozocin model of painful diabetic neuropathy in the rat Pain 81 1999 307 316
11. A. Fox, A. Kesingland, C. Gentry, K. McNair, S. Patel, L. Urban, and I. James The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain Pain 92 2001 91 100
12. J.A. Fuentes, M. Ruiz-Gayo, J. Manzanares, G. Vela, I. Reche, and J. Corchero Cannabinoids as potential new analgesics Life Sci. 65 1999 675 685
13. K. Hargreaves, R. Dubner, F. Brown, C. Flores, and J. Joris A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia Pain 32 1988 77 88
14. U. Herzberg, E. Eliav, G.J. Bennett, and I.J. Kopin The analgesic effect of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain Neurosci. Lett. 221 1997 157 160
15. S.H. Kim, and J.M. Chung An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat Pain 50 1992 355 363
16. G. Lim, B. Sung, R.-R. Ji, and J. Mao Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats Pain 105 2003 275 283
17. B.V. MacFarlane, A. Wright, J. O'Callaghan, and H.A.E. Benson Chronic neuropathic pain and its control by drugs Pharmacol. Ther. 75 1997 1 19
18. M. Malcangio, and D.R. Tomlinson A pharmacological analysis of mechanical hyperalgesia in streptozocin/diabetic rats Pain 76 1998 151 157
19. R.G. Pertwee Cannabinoid receptors and pain Progr. Neurobiol. 63 2001 569 611
20. J.D. Richardson Cannabinoids modulate pain by multiple mechanisms of action J. Pain 1 2000 2 14
21. N.M. Strangman, S.L. Patrick, A.G. Hohmann, K. Tsou, and J.M. Walker Evidence for a role of endogenous cannabinoids in the modulation of acute and tonic pain sensitivity Brain Res. 813 1998 323 328
22. A. Ulugol, A. Aslantas, Y. Ipci, A. Tuncer, H.C. Karadag, and I. Dokmeci Combined systemic administration of morphine and magnesium sulfate attenuates pain-related behavior in mononeuropathic rats Brain Res. 943 2002 101 104
23. A. Ulugol, H.C. Karadag, M. Tamer, Z. Firat, A. Aslantas, and I. Dokmeci Involvement of adenosine in the anti-allodynic effect of amitriptyline in streptozocin-induced diabetic rats Neurosci. Lett. 328 2002 129 132
24. J.M. Walker, and S.M. Huang Cannabinoid analgesia Pharmacol. Ther. 95 2002 127 135
25. C.P. Watson The treatment of neuropathic pain: antidepressants and opioids Clin. J. Pain. 16 2000 S49 S55
26. S.P. Welch, and M. Eads Synergistic interactions of endogenous opioids and cannabinoid systems Brain Res. 848 1999 183 190
27. O. Yesilyurt, A. Dogrul, H. Gul, M. Seyrek, O. Kusmez, Y. Ozkan, and O. Yildiz Topical cannabinoid enhances topical morphine antinociception Pain 105 2003 303 308