-
1
-
-
33645526144
-
Cancer Statistics, 2006
-
Jemal A, Siegel R, Ward E et al. Cancer Statistics, 2006. CA Cancer J. Clin. 56, 106-130 (2006).
-
(2006)
CA Cancer J. Clin
, vol.56
, pp. 106-130
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
7644224728
-
Validation of the postoperative nomogram for 12-year sarcoma specific death
-
Eilber FC, Brennan MF, Eilber FR et al. Validation of the postoperative nomogram for 12-year sarcoma specific death. Cancer 101(10), 2270-2275 (2004).
-
(2004)
Cancer
, vol.101
, Issue.10
, pp. 2270-2275
-
-
Eilber, F.C.1
Brennan, M.F.2
Eilber, F.R.3
-
3
-
-
0037315695
-
High-grade extremity soft tissue sarcomas factors predictive of local recurrence and its effect on morbidity and mortality
-
Eilber FC, Rosen G, Nelson SD et al. High-grade extremity soft tissue sarcomas factors predictive of local recurrence and its effect on morbidity and mortality. Ann. Surg. 237(2), 218-226 (2003).
-
(2003)
Ann. Surg
, vol.237
, Issue.2
, pp. 218-226
-
-
Eilber, F.C.1
Rosen, G.2
Nelson, S.D.3
-
4
-
-
10744227336
-
Soft tissue sarcomas of adults: State of the translational science
-
Borden EC, Baker LH, Bell RS et al. Soft tissue sarcomas of adults: state of the translational science. Clin. Cancer Res. 9, 1941-1956 (2003).
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 1941-1956
-
-
Borden, E.C.1
Baker, L.H.2
Bell, R.S.3
-
5
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 100, 57-70 (2000).
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
6
-
-
20044392290
-
Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control
-
Ohanna M, Sobering AK, Lapointe T et al. Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control. Nat. Cell Biol. 7(3), 286-294 (2005).
-
(2005)
Nat. Cell Biol
, vol.7
, Issue.3
, pp. 286-294
-
-
Ohanna, M.1
Sobering, A.K.2
Lapointe, T.3
-
7
-
-
33747819801
-
mTOR and cancer: Insights into a complex relationship
-
Sabatini DM. mTOR and cancer: insights into a complex relationship. Nat. Rev. Cancer 6(9), 729-734 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.9
, pp. 729-734
-
-
Sabatini, D.M.1
-
8
-
-
33845938611
-
A multicenter Phase 2 consortium (P2C) study of the mTOR inhibitor CCI-779 in advanced soft tissue sarcomas (STS)
-
Okuno SH, Mahoney MR, Bailey HH et al. A multicenter Phase 2 consortium (P2C) study of the mTOR inhibitor CCI-779 in advanced soft tissue sarcomas (STS). J. Clin. Oncol. 24(S18), 9504 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.S18
, pp. 9504
-
-
Okuno, S.H.1
Mahoney, M.R.2
Bailey, H.H.3
-
9
-
-
33750238350
-
Updated results of a Phase II trial of AP23573, a novel mTOR inhibitor, in patients (pts) with advanced soft tissue or bone sarcomas
-
Chawla SP, Tolcher AW, Staddon AP et al. Updated results of a Phase II trial of AP23573, a novel mTOR inhibitor, in patients (pts) with advanced soft tissue or bone sarcomas. J. Clin. Oncol. 24(S18), 9505 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.S18
, pp. 9505
-
-
Chawla, S.P.1
Tolcher, A.W.2
Staddon, A.P.3
-
10
-
-
0031039243
-
The biology of vascular endothelial growth factor
-
Ferrara N, Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr. Rev. 18(1), 4-25 (1997).
-
(1997)
Endocr. Rev
, vol.18
, Issue.1
, pp. 4-25
-
-
Ferrara, N.1
Davis-Smyth, T.2
-
11
-
-
0036785468
-
Characterization of 11 human sarcoma cell strains: Evaluation of cytogenetics, tumorigenicity, metastasis, and production of angiogenic factors
-
Hu M, Nicolson GL, Trent JC et al. Characterization of 11 human sarcoma cell strains: evaluation of cytogenetics, tumorigenicity, metastasis, and production of angiogenic factors. Cancer 95(7), 1569-1576 (2002).
-
(2002)
Cancer
, vol.95
, Issue.7
, pp. 1569-1576
-
-
Hu, M.1
Nicolson, G.L.2
Trent, J.C.3
-
12
-
-
0032884917
-
Serum levels of vascular endothelial growth factor and basic fibroblast growth factor in patients with soft-tissue sarcoma
-
Graeven U, Andre N, Achilles E et al. Serum levels of vascular endothelial growth factor and basic fibroblast growth factor in patients with soft-tissue sarcoma. J. Cancer Res. Clin. Oncol. 125(10), 577-581 (1999).
-
(1999)
J. Cancer Res. Clin. Oncol
, vol.125
, Issue.10
, pp. 577-581
-
-
Graeven, U.1
Andre, N.2
Achilles, E.3
-
13
-
-
0034073190
-
Patterns of expression and secretion of vascular endothelial growth factor in malignant soft-tissue tumours
-
Kuhnen C, Lehnhardt M, Tolnay E et al. Patterns of expression and secretion of vascular endothelial growth factor in malignant soft-tissue tumours. J. Cancer Res. Clin. Oncol. 126(4), 219-225 (2000).
-
(2000)
J. Cancer Res. Clin. Oncol
, vol.126
, Issue.4
, pp. 219-225
-
-
Kuhnen, C.1
Lehnhardt, M.2
Tolnay, E.3
-
14
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362(6423), 841-844 (1993).
-
(1993)
Nature
, vol.362
, Issue.6423
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
-
15
-
-
13444278498
-
Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies
-
Gerber HP, Ferrara N. Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies. Cancer Res. 65, 671-680 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 671-680
-
-
Gerber, H.P.1
Ferrara, N.2
-
16
-
-
0038327794
-
Efficacy and toxicity of the angiogenesis inhibitor SU5416 as a single agent in patients with advanced renal cell carcinoma, melanoma, and soft tissue sarcoma
-
Kuenen BC, Tabernero J, Baselga J et al. Efficacy and toxicity of the angiogenesis inhibitor SU5416 as a single agent in patients with advanced renal cell carcinoma, melanoma, and soft tissue sarcoma. Clin. Cancer Res. 9, 1648-1655 (2003).
-
(2003)
Clin. Cancer Res
, vol.9
, pp. 1648-1655
-
-
Kuenen, B.C.1
Tabernero, J.2
Baselga, J.3
-
17
-
-
4444250452
-
Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas
-
Heymach JV, Desai J, Manola J et al. Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas. Clin. Cancer Res. 10, 5732-5740 (2004).
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 5732-5740
-
-
Heymach, J.V.1
Desai, J.2
Manola, J.3
-
18
-
-
14544305077
-
Combination of antiangiogenic therapy with other anticancer therapies: Results, challenges, and open questions
-
Gasparini G, Longo R, Fanelli M et al. Combination of antiangiogenic therapy with other anticancer therapies: results, challenges, and open questions. J. Clin. Oncol. 23(6), 1295-1311 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.6
, pp. 1295-1311
-
-
Gasparini, G.1
Longo, R.2
Fanelli, M.3
-
19
-
-
27244450145
-
Phase II study of doxorubicin and bevacizumab for patients with metastatic soft-tissue sarcomas
-
D'Adamo DR, Anderson SE, Albritton K et al. Phase II study of doxorubicin and bevacizumab for patients with metastatic soft-tissue sarcomas. J. Clin. Oncol. 23(28), 7135-7142 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.28
, pp. 7135-7142
-
-
D'Adamo, D.R.1
Anderson, S.E.2
Albritton, K.3
-
20
-
-
0036249764
-
Altered expression of G1 regulatory proteins in human soft tissue sarcomas
-
Yoo J, Park SY, Kang SJ et al. Altered expression of G1 regulatory proteins in human soft tissue sarcomas. Arch. Pathol. Lab. Med. 26(5), 567-573 (2002).
-
(2002)
Arch. Pathol. Lab. Med
, vol.26
, Issue.5
, pp. 567-573
-
-
Yoo, J.1
Park, S.Y.2
Kang, S.J.3
-
21
-
-
0029665778
-
Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells
-
Carlson BA, Dubay MM, Sausville EA et al. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. Cancer Res. 56(13), 2973-2978 (1996).
-
(1996)
Cancer Res
, vol.56
, Issue.13
, pp. 2973-2978
-
-
Carlson, B.A.1
Dubay, M.M.2
Sausville, E.A.3
-
22
-
-
0034019911
-
Flavopiridol, a cyclin-dependent kinase inhibitor, prevents spindle inhibitor-induced endoreduplication in human cancer cells
-
Motwani M, Li X, Schwartz G. Flavopiridol, a cyclin-dependent kinase inhibitor, prevents spindle inhibitor-induced endoreduplication in human cancer cells. Clin. Cancer Res. 6, 924-932 (2000).
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 924-932
-
-
Motwani, M.1
Li, X.2
Schwartz, G.3
-
23
-
-
33749513203
-
A Phase II study of flavopiridol in patients with previously untreated advanced soft tissue sarcoma
-
Morris DG, Bramwell VHC, Turcotte R et al. A Phase II study of flavopiridol in patients with previously untreated advanced soft tissue sarcoma. Sarcoma 2006, 1-7 (2006).
-
(2006)
Sarcoma
, vol.2006
, pp. 1-7
-
-
Morris, D.G.1
Bramwell, V.H.C.2
Turcotte, R.3
-
24
-
-
0035866789
-
Selective sensitization of retinoblastoma protein-deficient sarcoma cells to doxorubicin by flavopiridol-mediated inhibition of cyclin-dependent kinase 2 kinase activity
-
Li W, Fan J, Bertino JR. Selective sensitization of retinoblastoma protein-deficient sarcoma cells to doxorubicin by flavopiridol-mediated inhibition of cyclin-dependent kinase 2 kinase activity. Cancer Res. 61(6), 2579-2582 (2001).
-
(2001)
Cancer Res
, vol.61
, Issue.6
, pp. 2579-2582
-
-
Li, W.1
Fan, J.2
Bertino, J.R.3
-
25
-
-
33947402995
-
A Phase I trial of doxorubicin and flavopiridol in soft tissue sarcoma
-
D'Adamo DR, Scheu K, Singer S et al. A Phase I trial of doxorubicin and flavopiridol in soft tissue sarcoma. J. Clin. Oncol. 24(S18), 9523 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.S18
, pp. 9523
-
-
D'Adamo, D.R.1
Scheu, K.2
Singer, S.3
-
26
-
-
33751581196
-
Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics
-
Chen Z, Xia Z, Gu WZ et al. Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics. Int. J. Cancer 119(12), 2784-2794 (2006).
-
(2006)
Int. J. Cancer
, vol.119
, Issue.12
, pp. 2784-2794
-
-
Chen, Z.1
Xia, Z.2
Gu, W.Z.3
-
27
-
-
33746388284
-
Modulation of cell cycle progression in human tumors: A pharmacokinetic and tumor molecular pharmacodynamic study of cisplatin plus the Chk1 inhibitor UCN-01 (NSC 638850)
-
Perez RP, Lewis LD, Beelen AP et al. Modulation of cell cycle progression in human tumors: a pharmacokinetic and tumor molecular pharmacodynamic study of cisplatin plus the Chk1 inhibitor UCN-01 (NSC 638850). Clin. Cancer Res. 12(23), 7079-7085 (2006).
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.23
, pp. 7079-7085
-
-
Perez, R.P.1
Lewis, L.D.2
Beelen, A.P.3
-
28
-
-
0344406759
-
Selective killing of cancer cells by β-lapachone: Direct checkpoint activation as a strategy against cancer
-
Li Y, Sun X, LaMont JT et al. Selective killing of cancer cells by β-lapachone: direct checkpoint activation as a strategy against cancer. Proc. Natl Acad. Sci. 100(5), 2674-2678 (2003).
-
(2003)
Proc. Natl Acad. Sci
, vol.100
, Issue.5
, pp. 2674-2678
-
-
Li, Y.1
Sun, X.2
LaMont, J.T.3
-
29
-
-
33748927997
-
A Phase Ib trial of ARQ 501, a selective checkpoint activator, in combination with docetaxel in patients with advanced solid tumors
-
Li C, Nemunaitis J, Senzer N et al. A Phase Ib trial of ARQ 501, a selective checkpoint activator, in combination with docetaxel in patients with advanced solid tumors. J. Clin. Oncol. 24(S18), 13053 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.S18
, pp. 13053
-
-
Li, C.1
Nemunaitis, J.2
Senzer, N.3
-
30
-
-
0033212968
-
Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5
-
Hymowitz SG, Christmyer HW, Fuh G et al. Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5. Mol. Cell 4(4), 563-571 (1999).
-
(1999)
Mol. Cell
, vol.4
, Issue.4
, pp. 563-571
-
-
Hymowitz, S.G.1
Christmyer, H.W.2
Fuh, G.3
-
31
-
-
33847167668
-
A Phase I safety and pharmacokinetic (PK) study of recombinant. Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer
-
Herbst RS, Mendolson DS, Ebbinghaus S et al. A Phase I safety and pharmacokinetic (PK) study of recombinant. Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer. J. Clin. Oncol. 24(S18), 3013 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.S18
, pp. 3013
-
-
Herbst, R.S.1
Mendolson, D.S.2
Ebbinghaus, S.3
-
32
-
-
33845913216
-
Intracellular and extracellular functions of heat shock proteins: Repercussions in cancer therapy
-
Schmitt E, Gehrmann M, Brunet M et al. Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy. J. Leuk. Biol. 81(1), 15-27 (2007).
-
(2007)
J. Leuk. Biol
, vol.81
, Issue.1
, pp. 15-27
-
-
Schmitt, E.1
Gehrmann, M.2
Brunet, M.3
-
33
-
-
23044509650
-
Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin prevents synovial sarcoma proliferation via apoptosis in in vitro models
-
Terry J, Lubieniecka JM, Kwan W et al. Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin prevents synovial sarcoma proliferation via apoptosis in in vitro models. Clin. Cancer Res. 11(15), 5631-5638 (2005).
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.15
, pp. 5631-5638
-
-
Terry, J.1
Lubieniecka, J.M.2
Kwan, W.3
-
34
-
-
33745156302
-
Phase 1/2 study of STA-4783, a novel heat shock protein 70 (hsp70) inducer, in combination with paclitaxel in patient with soft tissue sarcomas (STS)
-
Sherman ML, Ryan C, Blackstein M et al. Phase 1/2 study of STA-4783, a novel heat shock protein 70 (hsp70) inducer, in combination with paclitaxel in patient with soft tissue sarcomas (STS). J. Clin. Oncol. 23(S16), 9069 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.S16
, pp. 9069
-
-
Sherman, M.L.1
Ryan, C.2
Blackstein, M.3
-
36
-
-
18044375060
-
Phase I vaccination trial of SYT-SSX junction peptide in patients with disseminated synovial sarcoma
-
Kawaguchi S, Wada T, Ida K et al. Phase I vaccination trial of SYT-SSX junction peptide in patients with disseminated synovial sarcoma. J. Transl. Med. 3(1), 1 (2005).
-
(2005)
J. Transl. Med
, vol.3
, Issue.1
, pp. 1
-
-
Kawaguchi, S.1
Wada, T.2
Ida, K.3
-
37
-
-
0344873125
-
Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene
-
Xie Y, Tornkvist M, Aalto Y. Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene. Oncogene 22, 7628-7631 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 7628-7631
-
-
Xie, Y.1
Tornkvist, M.2
Aalto, Y.3
-
38
-
-
28844448329
-
Therapeutic potential of antibodies against FZD10, a cell surface protein, for synovial sarcomas
-
Nagayama S, Fukukawa C, Katagiri T et al. Therapeutic potential of antibodies against FZD10, a cell surface protein, for synovial sarcomas. Oncogene 24, 6201-6212 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 6201-6212
-
-
Nagayama, S.1
Fukukawa, C.2
Katagiri, T.3
-
39
-
-
22144456041
-
The promise of molecular targeted therapies: Protein kinase inhibitors in the treatment of cutaneous malignancies
-
Kondapalli L, Soltani K, Lacouture ME. The promise of molecular targeted therapies: protein kinase inhibitors in the treatment of cutaneous malignancies. J. Am. Acad. Dermatol. 53, 291-302 (2005).
-
(2005)
J. Am. Acad. Dermatol
, vol.53
, pp. 291-302
-
-
Kondapalli, L.1
Soltani, K.2
Lacouture, M.E.3
-
40
-
-
14144256775
-
Molecular and clinical analysis of locally advanced dermatofibrosarcoma protuberans treated with imatinib: Imatinib target exploration consortium study B2225
-
McArthur GA, Demetri GD, Oosterom A et al. Molecular and clinical analysis of locally advanced dermatofibrosarcoma protuberans treated with imatinib: imatinib target exploration consortium study B2225. J. Clin. Oncol. 23, 866-873 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 866-873
-
-
McArthur, G.A.1
Demetri, G.D.2
Oosterom, A.3
-
41
-
-
20844459809
-
Imatinib mesylate in chordoma
-
Casali PG, Messina A, Stacchiotti S et al. Imatinib mesylate in chordoma. Cancer 101(9), 2086-2097 (2004).
-
(2004)
Cancer
, vol.101
, Issue.9
, pp. 2086-2097
-
-
Casali, P.G.1
Messina, A.2
Stacchiotti, S.3
-
42
-
-
34249286769
-
Imatinib mesylate in 18 advanced chordoma patients
-
Casali PG, Stacchiotti S, Messina A et al. Imatinib mesylate in 18 advanced chordoma patients. J. Clin. Oncol. 23(S16), 9012 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.S16
, pp. 9012
-
-
Casali, P.G.1
Stacchiotti, S.2
Messina, A.3
-
43
-
-
0030884089
-
The role of adjuvant radiotherapy in the treatment of resectable desmoid tumors
-
Goy BW, Lee SP, Eilber F et al. The role of adjuvant radiotherapy in the treatment of resectable desmoid tumors. Int. J. Radiat. Oncol. Biol. Phys. 39(3), 659-665 (1997).
-
(1997)
Int. J. Radiat. Oncol. Biol. Phys
, vol.39
, Issue.3
, pp. 659-665
-
-
Goy, B.W.1
Lee, S.P.2
Eilber, F.3
-
44
-
-
0031736788
-
Treatment results of unresected or partially resected desmoid tumors
-
Goy BW, Lee SP, Fu YS et al. Treatment results of unresected or partially resected desmoid tumors. Am. J. Clin. Oncol. 21(6), 584-590 (1998).
-
(1998)
Am. J. Clin. Oncol
, vol.21
, Issue.6
, pp. 584-590
-
-
Goy, B.W.1
Lee, S.P.2
Fu, Y.S.3
-
45
-
-
33644977853
-
Clinical and molecular studies of the effect of imatinib on advanced aggressive fibromatosis (desmoid tumor)
-
Heinrich MC, McArthur GA, Demetri GD et al. Clinical and molecular studies of the effect of imatinib on advanced aggressive fibromatosis (desmoid tumor). J. Clin. Oncol. 24(7), 1195-1203 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.7
, pp. 1195-1203
-
-
Heinrich, M.C.1
McArthur, G.A.2
Demetri, G.D.3
-
46
-
-
34249300612
-
-
Evilevitch V, Weber W, Tap W et al. Change in quantitative FDG-PET was significantly more accurate than change in size at predicting histopathologic response to neoadjuvant therapy in high grade soft tissue sarcomas. Presented at: Am. Soc. Clin. Oncol. Chicago, IL, USA 1-5 June, 2007.
-
Evilevitch V, Weber W, Tap W et al. Change in quantitative FDG-PET was significantly more accurate than change in size at predicting histopathologic response to neoadjuvant therapy in high grade soft tissue sarcomas. Presented at: Am. Soc. Clin. Oncol. Chicago, IL, USA 1-5 June, 2007.
-
-
-
-
47
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
Ventura A, Kirsch DG, McLaughlin ME et al. Restoration of p53 function leads to tumour regression in vivo. Nature 445, 661-665 (2007).
-
(2007)
Nature
, vol.445
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
-
48
-
-
33745679352
-
Telomerase therapeutics for cancer: Challenges and new directions
-
Shay JW, Wright WE. Telomerase therapeutics for cancer: challenges and new directions. Nat. Rev. Drug Disc. 5(7), 577-584 (2006).
-
(2006)
Nat. Rev. Drug Disc
, vol.5
, Issue.7
, pp. 577-584
-
-
Shay, J.W.1
Wright, W.E.2
-
49
-
-
33947313218
-
HDACs, histone deacetylation and gene transcription: From molecular biology to cancer therapeutics
-
Gallinari P, Di Marco S, Jones P et al. HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics. Cell Res. 17, 195-211 (2007).
-
(2007)
Cell Res
, vol.17
, pp. 195-211
-
-
Gallinari, P.1
Di Marco, S.2
Jones, P.3
-
50
-
-
33846673934
-
An antagonist of dishevelled protein-protein interaction suppresses β-catenin-dependent tumor cell growth
-
Fuji N, You L, Xu Z et al. An antagonist of dishevelled protein-protein interaction suppresses β-catenin-dependent tumor cell growth. Cancer Res. 67(2), 573-579 (2007).
-
(2007)
Cancer Res
, vol.67
, Issue.2
, pp. 573-579
-
-
Fuji, N.1
You, L.2
Xu, Z.3
-
51
-
-
31544464616
-
In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I /insulin receptor inhibitor, BMS-554417
-
Haluska P, Carboni JM, Loegering DA et al. In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I /insulin receptor inhibitor, BMS-554417. Cancer Res. 66(1), 362-371 (2006).
-
(2006)
Cancer Res
, vol.66
, Issue.1
, pp. 362-371
-
-
Haluska, P.1
Carboni, J.M.2
Loegering, D.A.3
-
52
-
-
34047265691
-
Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on Src kinase for survival
-
Shor AS, Keschman EA, Lee FY et al. Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on Src kinase for survival. Cancer Res. 67(6), 2800-2808 (2007).
-
(2007)
Cancer Res
, vol.67
, Issue.6
, pp. 2800-2808
-
-
Shor, A.S.1
Keschman, E.A.2
Lee, F.Y.3
-
53
-
-
33749538874
-
The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models
-
Ying H, Biroc SL, Li W et al. The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models. Mol. Cancer Ther. 5(9), 2158-2164 (2006).
-
(2006)
Mol. Cancer Ther
, vol.5
, Issue.9
, pp. 2158-2164
-
-
Ying, H.1
Biroc, S.L.2
Li, W.3
-
54
-
-
33646878087
-
Efficacy of siRNA nanocapsules targeted against the EWS-FLI1 oncogene in Ewing sarcoma
-
Toub N, Bertrand JR, Tamaddon A et al. Efficacy of siRNA nanocapsules targeted against the EWS-FLI1 oncogene in Ewing sarcoma. Pharm. Res. 23(5), 892-900 (2006).
-
(2006)
Pharm. Res
, vol.23
, Issue.5
, pp. 892-900
-
-
Toub, N.1
Bertrand, J.R.2
Tamaddon, A.3
-
55
-
-
0029826488
-
Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins
-
Bernasconi M, Remppis, Fredericks WJ et al. Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins. Proc. Natl Acad. Sci. USA 93(23), 13164-13169 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, Issue.23
, pp. 13164-13169
-
-
Bernasconi, M.1
-
56
-
-
2942622488
-
Targeting of EWS/FLI-1 RNA intererference attenuates tumor phenotype of Ewing's sarcoma cells in vitro
-
Chansky HA, Barahmand-Pour F, Mei Q et al. Targeting of EWS/FLI-1 RNA intererference attenuates tumor phenotype of Ewing's sarcoma cells in vitro. J. Orthop. Res. 22(4), 910-917 (2004).
-
(2004)
J. Orthop. Res
, vol.22
, Issue.4
, pp. 910-917
-
-
Chansky, H.A.1
Barahmand-Pour, F.2
Mei, Q.3
-
57
-
-
0038489117
-
Small interfering RNAs expressed from a Pol II promoter suppress the EWS/Fli-1 transcript in an Ewing sarcoma cell line
-
Dohjima T, Lee NS, Li H et al. Small interfering RNAs expressed from a Pol II promoter suppress the EWS/Fli-1 transcript in an Ewing sarcoma cell line. Mol. Ther. 7(6), 811-816 (2003).
-
(2003)
Mol. Ther
, vol.7
, Issue.6
, pp. 811-816
-
-
Dohjima, T.1
Lee, N.S.2
Li, H.3
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